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The map label for this gene is dinB [H]

Identifier: 161510117

GI number: 161510117

Start: 2036511

End: 2037551

Strand: Reverse

Name: dinB [H]

Synonym: USA300HOU_1894

Alternate gene names: 161510117

Gene position: 2037551-2036511 (Counterclockwise)

Preceding gene: 161510118

Following gene: 161510115

Centisome position: 70.92

GC content: 34.58

Gene sequence:

>1041_bases
ATGGACTATTTTTTTGCACAAGTCGAAATGAGAGATAACCCCAAATTGAAAGGGAAACCAGTCATTGTTGGTGGTAAAGC
AAGCAGTAGGGGTGTTGTCTCTACGGCATCCTATGAAGCACGAAAATACGGCGTCCATTCAGCAATGCCTATGTCACAAG
CGCATAAATTATGTCCAAATGGATACTTTGTCACAAGTAATTTTGGTGCTTACCGAGAAACATCTGCGCAGATTATGTCT
ATTTTCCGAAGTTATACAGATAAGGTAGAACCGATGTCATTGGATGAAGCGTATTTAGATATTACAGAATTAGTGAGACC
AGACCTTCCTGCTTCGAAAATTGCTCAGTATATTAGAAAAGATATTCTAGAGCAGACACATTTAACAGCATCTGCAGGTG
TTTCTTATAACAAATTTTTAGCTAAATTAGCGAGTGGTATGAATAAACCTGATGGTATGACTGTGATTGATTATCAAAAT
GTCCATGATATTTTGATGACATTGGATATTGGAGATTTTCCAGGCGTAGGTAAAGCTTCCAAAAAAGTAATGCATGATAA
TGGTATTTTTAACGGTAGAGATTTATATGAGAAAACGGAATTTGAATTAATACGTTTGTTTGGAAAAAGAGGTCGGGGTT
TATATAACAAGGCACGCGGTATTGACCATAGTGAAGTGAAATCATCAAGAGTAAGAAAATCAGTAGGGACTGAACGCACA
TTTGCAACAGACGTGAATGATGATGAAGAGATTTTAAGAAAAGTATGGGAATTGTCAGGTAAAACAGCTGAACGTCTAAA
TAAATTACAGAAGTCAGCTAAAACTGTAACGGTTAAAATTAAAACTTATCAATTTGAAACGCTATCTAAACAGATGAGTT
TAAGAGATTCGGTTAGTTCTGAAGAAGATATTTATAATATTGCATATTTACTTTATAACGATTTAAAAGACCCTGATGTA
CCAATTCGACTTATTGGTGTCACTGTAGGTAATTTAGAACAATCAACTTATAAAAATATGACGATATATGACTTTATATA
A

Upstream 100 bases:

>100_bases
ACACAGCGTATAATTATGTTGAGATATTTTTGTGCGTTATAAAAGTAAAAATTAGTAGGGAGGTGAGCACTTGACTGAGA
GACGAATTATTCATATAGAT

Downstream 100 bases:

>100_bases
AATAAAGCTCCCTGCAAAGTTTACATTTTTACAATGCTTACTTTTGAAGGGAGTATTTTATTTAGTCCTAGCCTTTATCT
TTTAGATTTTTACCATAAAT

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGAYRETSAQIMS
IFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKPDGMTVIDYQN
VHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSRVRKSVGTERT
FATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYLLYNDLKDPDV
PIRLIGVTVGNLEQSTYKNMTIYDFI

Sequences:

>Translated_346_residues
MDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGAYRETSAQIMS
IFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKPDGMTVIDYQN
VHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSRVRKSVGTERT
FATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYLLYNDLKDPDV
PIRLIGVTVGNLEQSTYKNMTIYDFI
>Mature_346_residues
MDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGAYRETSAQIMS
IFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKPDGMTVIDYQN
VHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSRVRKSVGTERT
FATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYLLYNDLKDPDV
PIRLIGVTVGNLEQSTYKNMTIYDFI

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI7706681, Length=334, Percent_Identity=30.5389221556886, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI84043967, Length=333, Percent_Identity=30.6306306306306, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI5729982, Length=341, Percent_Identity=29.9120234604106, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI154350220, Length=323, Percent_Identity=29.4117647058824, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI7705344, Length=246, Percent_Identity=31.7073170731707, Blast_Score=105, Evalue=9e-23,
Organism=Escherichia coli, GI1786425, Length=291, Percent_Identity=45.360824742268, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI1787432, Length=296, Percent_Identity=26.6891891891892, Blast_Score=86, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI193205700, Length=412, Percent_Identity=29.126213592233, Blast_Score=136, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17537959, Length=369, Percent_Identity=27.3712737127371, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI115534089, Length=385, Percent_Identity=26.2337662337662, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI193205702, Length=364, Percent_Identity=26.6483516483516, Blast_Score=92, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6324921, Length=201, Percent_Identity=28.8557213930348, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19923006, Length=404, Percent_Identity=25.990099009901, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI21355641, Length=277, Percent_Identity=28.5198555956679, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24644984, Length=277, Percent_Identity=28.5198555956679, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24668444, Length=348, Percent_Identity=26.1494252873563, Blast_Score=95, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 39050; Mature: 39050

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPN
CCEEEEEEEECCCCCCCCCCEEEECCCCCCCCEEECCHHHHHHCCCCCCCHHHHHHHCCC
GYFVTSNFGAYRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRK
CEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
DILEQTHLTASAGVSYNKFLAKLASGMNKPDGMTVIDYQNVHDILMTLDIGDFPGVGKAS
HHHHHHHCHHHCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEECCCCCCCCHHH
KKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSRVRKSVGTERT
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCE
FATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSS
EECCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEEEEEHHHHHHHHHHHHCCCC
EEDIYNIAYLLYNDLKDPDVPIRLIGVTVGNLEQSTYKNMTIYDFI
HHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCHHHHCCCEEEECC
>Mature Secondary Structure
MDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPN
CCEEEEEEEECCCCCCCCCCEEEECCCCCCCCEEECCHHHHHHCCCCCCCHHHHHHHCCC
GYFVTSNFGAYRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRK
CEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
DILEQTHLTASAGVSYNKFLAKLASGMNKPDGMTVIDYQNVHDILMTLDIGDFPGVGKAS
HHHHHHHCHHHCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEECCCCCCCCHHH
KKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSRVRKSVGTERT
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCE
FATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSS
EECCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEEEEEHHHHHHHHHHHHCCCC
EEDIYNIAYLLYNDLKDPDVPIRLIGVTVGNLEQSTYKNMTIYDFI
HHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA