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The map label for this gene is dgk [H]

Identifier: 161508797

GI number: 161508797

Start: 608501

End: 609163

Strand: Reverse

Name: dgk [H]

Synonym: USA300HOU_0551

Alternate gene names: 161508797

Gene position: 609163-608501 (Counterclockwise)

Preceding gene: 161508805

Following gene: 161508796

Centisome position: 21.2

GC content: 26.7

Gene sequence:

>663_bases
ATGGTACAATACTCAATGTCTATTTTAACATTTGGAGATGTGAATATGAACAAACCTTTTATAGCAATTGAAGGTCCTAT
TGGCGTAGGTAAATCTTCACTTGCACACAAATTAAGTCAAACTTTAGATTTTTATGAAGAAAAAGAAATCATCACAGAAA
ATCCATTTTTATCAGACTTTTATGAAGATATCTCTAAATGGAGTTTTCAAACTGAAATGTTCTTTTTATGCAATAGATAT
AAGCAATTTCAAGATGTAACACAACTAAATCAAGGTGTAGTTAGTGATTATCATATACATAAAAATAAGATATTTGCTAA
AAATACTTTGAGTTCTGTTGAATTTCAGAAATTCAGTAAAATTTATGATATTTTAACTGAAGATATGATTATGCCGAATA
TGATTATCTTTTTAGATGCAGACCTTGATGTGTTAAAATCTAGAATTGCTAAACGTAACCGTAGTTTTGAGCATCAAATA
GAAGATGAATATCTGTTAAAGTTAAAAAAAGATTATCGTGAGTATTATGAGTCCTTACAAAGTAATGGTTCAAATGTAGT
TTTAATCGATACAACTTCTATTGATTTTCTTAAAAATGAACAAGATTACGAAGATATATTACATATTATATTACCTATGA
TAGGAGATATTACCAATGAATAA

Upstream 100 bases:

>100_bases
CTATAGGTACTTCGCCTAGTTGAGCTGCTTTTTTAGCTTCTTCAATCGCTAATGTCATAAAATATATATCATTTGTCATT
TATGTCCAGATACCTCACTT

Downstream 100 bases:

>100_bases
TTACGGTATTCCACAAAATGCCATTATAACCATTGCAGGTACAGTTGGTGTTGGAAAATCAACACTAACGCAAGCACTTG
CAGATAAATTAAACTTTAAA

Product: deoxynucleoside kinase

Products: NA

Alternate protein names: DGUO kinase; dGK [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MVQYSMSILTFGDVNMNKPFIAIEGPIGVGKSSLAHKLSQTLDFYEEKEIITENPFLSDFYEDISKWSFQTEMFFLCNRY
KQFQDVTQLNQGVVSDYHIHKNKIFAKNTLSSVEFQKFSKIYDILTEDMIMPNMIIFLDADLDVLKSRIAKRNRSFEHQI
EDEYLLKLKKDYREYYESLQSNGSNVVLIDTTSIDFLKNEQDYEDILHIILPMIGDITNE

Sequences:

>Translated_220_residues
MVQYSMSILTFGDVNMNKPFIAIEGPIGVGKSSLAHKLSQTLDFYEEKEIITENPFLSDFYEDISKWSFQTEMFFLCNRY
KQFQDVTQLNQGVVSDYHIHKNKIFAKNTLSSVEFQKFSKIYDILTEDMIMPNMIIFLDADLDVLKSRIAKRNRSFEHQI
EDEYLLKLKKDYREYYESLQSNGSNVVLIDTTSIDFLKNEQDYEDILHIILPMIGDITNE
>Mature_220_residues
MVQYSMSILTFGDVNMNKPFIAIEGPIGVGKSSLAHKLSQTLDFYEEKEIITENPFLSDFYEDISKWSFQTEMFFLCNRY
KQFQDVTQLNQGVVSDYHIHKNKIFAKNTLSSVEFQKFSKIYDILTEDMIMPNMIIFLDADLDVLKSRIAKRNRSFEHQI
EDEYLLKLKKDYREYYESLQSNGSNVVLIDTTSIDFLKNEQDYEDILHIILPMIGDITNE

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as ph

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 25841; Mature: 25841

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQYSMSILTFGDVNMNKPFIAIEGPIGVGKSSLAHKLSQTLDFYEEKEIITENPFLSDF
CCEEEEEEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
YEDISKWSFQTEMFFLCNRYKQFQDVTQLNQGVVSDYHIHKNKIFAKNTLSSVEFQKFSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEECCCEEEHHHHHHHHHHHHHHH
IYDILTEDMIMPNMIIFLDADLDVLKSRIAKRNRSFEHQIEDEYLLKLKKDYREYYESLQ
HHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SNGSNVVLIDTTSIDFLKNEQDYEDILHIILPMIGDITNE
CCCCEEEEEECCCHHHHCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVQYSMSILTFGDVNMNKPFIAIEGPIGVGKSSLAHKLSQTLDFYEEKEIITENPFLSDF
CCEEEEEEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
YEDISKWSFQTEMFFLCNRYKQFQDVTQLNQGVVSDYHIHKNKIFAKNTLSSVEFQKFSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEECCCEEEHHHHHHHHHHHHHHH
IYDILTEDMIMPNMIIFLDADLDVLKSRIAKRNRSFEHQIEDEYLLKLKKDYREYYESLQ
HHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SNGSNVVLIDTTSIDFLKNEQDYEDILHIILPMIGDITNE
CCCCEEEEEECCCHHHHCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]