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The map label for this gene is dck [H]

Identifier: 161508796

GI number: 161508796

Start: 607846

End: 608508

Strand: Reverse

Name: dck [H]

Synonym: USA300HOU_0550

Alternate gene names: 161508796

Gene position: 608508-607846 (Counterclockwise)

Preceding gene: 161508797

Following gene: 161508788

Centisome position: 21.18

GC content: 32.13

Gene sequence:

>663_bases
ATGAATAATTACGGTATTCCACAAAATGCCATTATAACCATTGCAGGTACAGTTGGTGTTGGAAAATCAACACTAACGCA
AGCACTTGCAGATAAATTAAACTTTAAAACGTCTTTTGAAAATGTCGAACATAATCCATATTTAGATAAATTTTACAGCG
ATTTTGAACGATGGAGTTTCCATTTGCAAATTTACTTCTTAGCTGAACGTTTTAAAGAACAAAAGCGTATGTTTGAATAT
GGTGGTGGCTTTGTCCAAGATCGATCAATTTATGAAGATGTTGATATTTTTGCAAAAATGCATGAAGAAGAAGGCACAAT
GAGTAAAGAAGATTTCAAAACATATTCAGACTTATTTAATGCCATGGTCATGACACCTTATTTTCCTAAACCTGATGTAA
TGATTTATTTAGAATGTAACTATGATGAGGTCATTGATCGTATTATTGAACGTGGTCGCGAAATGGAAATTAATACAGAC
CCTGAATACTGGAAAAAGCTATTTAAACGCTATGACGATTGGATTAATAGCTTTAATGCATGTCCAGTTGTACGTATCAA
TATTAATGAATATGATATCCATAAGGACCCCGAATCTTTAAATCCTATGATAAACAAAATTGCTCGAATTATTCAAACAT
ATCGACAAGTAGATACACGATAA

Upstream 100 bases:

>100_bases
GTAGTTTTAATCGATACAACTTCTATTGATTTTCTTAAAAATGAACAAGATTACGAAGATATATTACATATTATATTACC
TATGATAGGAGATATTACCA

Downstream 100 bases:

>100_bases
AAGACTAAAGACATAGCGTATATGTTTATATTCAATGTATATTCCATAGATATTATCGATTATTTTATCAATTCTATCGA
ATACATTAATTCACATATAC

Product: deoxynucleoside kinase

Products: NA

Alternate protein names: dAK/dCK [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MNNYGIPQNAIITIAGTVGVGKSTLTQALADKLNFKTSFENVEHNPYLDKFYSDFERWSFHLQIYFLAERFKEQKRMFEY
GGGFVQDRSIYEDVDIFAKMHEEEGTMSKEDFKTYSDLFNAMVMTPYFPKPDVMIYLECNYDEVIDRIIERGREMEINTD
PEYWKKLFKRYDDWINSFNACPVVRININEYDIHKDPESLNPMINKIARIIQTYRQVDTR

Sequences:

>Translated_220_residues
MNNYGIPQNAIITIAGTVGVGKSTLTQALADKLNFKTSFENVEHNPYLDKFYSDFERWSFHLQIYFLAERFKEQKRMFEY
GGGFVQDRSIYEDVDIFAKMHEEEGTMSKEDFKTYSDLFNAMVMTPYFPKPDVMIYLECNYDEVIDRIIERGREMEINTD
PEYWKKLFKRYDDWINSFNACPVVRININEYDIHKDPESLNPMINKIARIIQTYRQVDTR
>Mature_220_residues
MNNYGIPQNAIITIAGTVGVGKSTLTQALADKLNFKTSFENVEHNPYLDKFYSDFERWSFHLQIYFLAERFKEQKRMFEY
GGGFVQDRSIYEDVDIFAKMHEEEGTMSKEDFKTYSDLFNAMVMTPYFPKPDVMIYLECNYDEVIDRIIERGREMEINTD
PEYWKKLFKRYDDWINSFNACPVVRININEYDIHKDPESLNPMINKIARIIQTYRQVDTR

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dATP AND dCTP for DNA metabolism. The phosphate acceptor specificity is strict toward deoxyadenosine (dAdo) and deoxycytidine (dCyd). The specificity toward the sugar moiety of the n

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.74; =2.7.1.76 [H]

Molecular weight: Translated: 26228; Mature: 26228

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNYGIPQNAIITIAGTVGVGKSTLTQALADKLNFKTSFENVEHNPYLDKFYSDFERWSF
CCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHH
HLQIYFLAERFKEQKRMFEYGGGFVQDRSIYEDVDIFAKMHEEEGTMSKEDFKTYSDLFN
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
AMVMTPYFPKPDVMIYLECNYDEVIDRIIERGREMEINTDPEYWKKLFKRYDDWINSFNA
HHHHCCCCCCCCEEEEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
CPVVRININEYDIHKDPESLNPMINKIARIIQTYRQVDTR
CCEEEEECCCCCCCCCHHHCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNNYGIPQNAIITIAGTVGVGKSTLTQALADKLNFKTSFENVEHNPYLDKFYSDFERWSF
CCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHH
HLQIYFLAERFKEQKRMFEYGGGFVQDRSIYEDVDIFAKMHEEEGTMSKEDFKTYSDLFN
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
AMVMTPYFPKPDVMIYLECNYDEVIDRIIERGREMEINTDPEYWKKLFKRYDDWINSFNA
HHHHCCCCCCCCEEEEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
CPVVRININEYDIHKDPESLNPMINKIARIIQTYRQVDTR
CCEEEEECCCCCCCCCHHHCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]