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The map label for this gene is ptsG [H]

Identifier: 161508454

GI number: 161508454

Start: 221228

End: 223288

Strand: Reverse

Name: ptsG [H]

Synonym: USA300HOU_0203

Alternate gene names: 161508454

Gene position: 223288-221228 (Counterclockwise)

Preceding gene: 161508463

Following gene: 161508452

Centisome position: 7.77

GC content: 37.89

Gene sequence:

>2061_bases
TTGGAGGTTGGACAAGTGAGGAAGAAACTTTTCGGTCAATTGCAACGTATTGGTAAAGCGCTAATGTTACCTGTTGCGAT
TTTACCAGCAGCTGGTCTGTTATTAGCTATCGGTACAGCTATGCAAGGTGAATCATTACAACACTACTTGCCGTTTATAC
AAAATGGTGGCGTACAAACTGTCGCTAAATTAATGACAGGTGCTGGTGGTATCATTTTTGATAACTTGCCTATGATTTTC
GCATTAGGTGTCGCAATCGGATTAGCTGGCGGTGATGGCGTAGCAGCTATCGCAGCATTCGTCGGTTACATAATCATGAA
CAAAACAATGGGCGACTTTTTACAAGTTACACCTAAGAATATTGGTGATCCAGCGAGTGGTTACGCTAGCATTTTAGGTA
TCCCAACATTACAAACAGGTGTGTTCGGCGGTATTATAATCGGGGCCCTGGCAGCTTGGTGTTATAACAAGTTCTATAAC
ATTAACTTACCATCTTATTTAGGTTTCTTCGCTGGTAAGCGTTTCGTACCTATTATGATGGCTACAACATCATTTATTTT
AGCATTCCCAATGGCATTAATTTGGCCAACGATTCAATCAGGATTAAATGCATTCAGTACAGGATTATTAGATTCAAATA
CTGGTGTTGCCGTATTCTTATTTGGTTTCATCAAGCGTTTATTAATTCCATTCGGTCTACATCACATTTTCCACGCACCG
TTCTGGTTCGAGTTTGGTTCATGGAAAAATGCAGCTGGTGAAATTATTCACGGTGACCAACGTATCTTTATCGAACAAAT
TCGTGAAGGCGCACATTTGACAGCTGGTAAATTCATGCAAGGTGAATTCCCTGTTATGATGTTCGGTTTACCTGCAGCAG
CTTTAGCAATTTATCACACAGCTAAACCTGAAAATAAGAAAGTAGTAGCAGGTTTAATGGGTTCTGCTGCTTTAACATCA
TTCTTAACTGGTATTACAGAACCATTAGAATTCTCATTCTTATTTGTAGCACCATTATTATTCTTTATTCACGCAGTACT
TGATGGTTTATCATTCTTAACATTGTACTTATTAGATCTTCATCTAGGTTATACATTCTCAGGTGGTTTCATCGACTACT
TCTTACTCGGTATACTACCTAATAAGACACAATGGTGGTTAGTCATTCCTGTAGGTCTTGTATACGCAGTTATTTACTAC
TTCGTATTCCGATTCTTAATTGTAAAATTAAAATACAAAACACCAGGTCGTGAAGATAAACAATCACAAGCGGCTACTGC
TTCAGCAACTGAATTACCATATGCAGTATTAGAAGCTATGGGTGGCAAAGCAAACATTAAACATTTAGACGCTTGTATCA
CACGTCTACGTGTTGAAGTTAACGACAAATCTAAAGTTGATGTTCCTGGTTTGAAAGATTTAGGCGCATCTGGTGTATTA
GAAGTCGGCAATAATATGCAAGCAATTTTTGGTCCTAAATCTGACCAAATCAAACATGAAATGCAACAGATTATGAATGG
TCAAGTAGTAGAAAATCCTACTACTATGGAAGACGATAAAGACGAAACTGTTGTTGTTGCAGAAGATAAATCTGCAACAA
GCGAATTGAGCCATATCGTGCATGCACCATTAACTGGTGAAGTAACACCATTATCAGAAGTGCCTGATCAAGTGTTCAGC
GAAAAAATGATGGGTGACGGTATCGCTATCAAACCTTCACAAGGTGAAGTTCGTGCACCATTCAACGGTAAAGTACAAAT
GATTTTCCCAACAAAACATGCAATTGGTCTTGTATCAGATAGTGGTTTAGAACTATTAATCCACATCGGTTTAGACACTG
TTAAATTAAACGGAGAAGGCTTTACTTTACATGTTGAGGAAGGTCAAGAAGTTAAACAAGGTGATTTATTAATCAACTTT
GATTTAGACTACATCCGCAATCATGCAAAGAGTGATATTACGCCTATTATCGTGACACAAGGAAACATTACAAACCTTGA
TTTTAAACAAGGTGAACATGGCAACATTTCATTTGGCGATCAATTATTTGAAGCTAAATAA

Upstream 100 bases:

>100_bases
AAGTAAGATTAGGCATGAGTTAAATTAAGCTGTGATGGTTACCAACACAGTCTATTTGCTCGTGTCTTTTTTTATTGAAT
CTTAAATAATAAATACAACT

Downstream 100 bases:

>100_bases
TGCTTACTATAAACAGGTGCGTATACCTTCATAAGGTGACGCGCCTGTTTTTTCTTTGCTATTGTATTTTGCAGCATCAT
TGATAGTTCGCTCTCCCCTT

Product: PTS family glucose/glucoside (glc) porter component IIABC

Products: NA

Alternate protein names: EIICBA-Glc; EII-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 686; Mature: 686

Protein sequence:

>686_residues
MEVGQVRKKLFGQLQRIGKALMLPVAILPAAGLLLAIGTAMQGESLQHYLPFIQNGGVQTVAKLMTGAGGIIFDNLPMIF
ALGVAIGLAGGDGVAAIAAFVGYIIMNKTMGDFLQVTPKNIGDPASGYASILGIPTLQTGVFGGIIIGALAAWCYNKFYN
INLPSYLGFFAGKRFVPIMMATTSFILAFPMALIWPTIQSGLNAFSTGLLDSNTGVAVFLFGFIKRLLIPFGLHHIFHAP
FWFEFGSWKNAAGEIIHGDQRIFIEQIREGAHLTAGKFMQGEFPVMMFGLPAAALAIYHTAKPENKKVVAGLMGSAALTS
FLTGITEPLEFSFLFVAPLLFFIHAVLDGLSFLTLYLLDLHLGYTFSGGFIDYFLLGILPNKTQWWLVIPVGLVYAVIYY
FVFRFLIVKLKYKTPGREDKQSQAATASATELPYAVLEAMGGKANIKHLDACITRLRVEVNDKSKVDVPGLKDLGASGVL
EVGNNMQAIFGPKSDQIKHEMQQIMNGQVVENPTTMEDDKDETVVVAEDKSATSELSHIVHAPLTGEVTPLSEVPDQVFS
EKMMGDGIAIKPSQGEVRAPFNGKVQMIFPTKHAIGLVSDSGLELLIHIGLDTVKLNGEGFTLHVEEGQEVKQGDLLINF
DLDYIRNHAKSDITPIIVTQGNITNLDFKQGEHGNISFGDQLFEAK

Sequences:

>Translated_686_residues
MEVGQVRKKLFGQLQRIGKALMLPVAILPAAGLLLAIGTAMQGESLQHYLPFIQNGGVQTVAKLMTGAGGIIFDNLPMIF
ALGVAIGLAGGDGVAAIAAFVGYIIMNKTMGDFLQVTPKNIGDPASGYASILGIPTLQTGVFGGIIIGALAAWCYNKFYN
INLPSYLGFFAGKRFVPIMMATTSFILAFPMALIWPTIQSGLNAFSTGLLDSNTGVAVFLFGFIKRLLIPFGLHHIFHAP
FWFEFGSWKNAAGEIIHGDQRIFIEQIREGAHLTAGKFMQGEFPVMMFGLPAAALAIYHTAKPENKKVVAGLMGSAALTS
FLTGITEPLEFSFLFVAPLLFFIHAVLDGLSFLTLYLLDLHLGYTFSGGFIDYFLLGILPNKTQWWLVIPVGLVYAVIYY
FVFRFLIVKLKYKTPGREDKQSQAATASATELPYAVLEAMGGKANIKHLDACITRLRVEVNDKSKVDVPGLKDLGASGVL
EVGNNMQAIFGPKSDQIKHEMQQIMNGQVVENPTTMEDDKDETVVVAEDKSATSELSHIVHAPLTGEVTPLSEVPDQVFS
EKMMGDGIAIKPSQGEVRAPFNGKVQMIFPTKHAIGLVSDSGLELLIHIGLDTVKLNGEGFTLHVEEGQEVKQGDLLINF
DLDYIRNHAKSDITPIIVTQGNITNLDFKQGEHGNISFGDQLFEAK
>Mature_686_residues
MEVGQVRKKLFGQLQRIGKALMLPVAILPAAGLLLAIGTAMQGESLQHYLPFIQNGGVQTVAKLMTGAGGIIFDNLPMIF
ALGVAIGLAGGDGVAAIAAFVGYIIMNKTMGDFLQVTPKNIGDPASGYASILGIPTLQTGVFGGIIIGALAAWCYNKFYN
INLPSYLGFFAGKRFVPIMMATTSFILAFPMALIWPTIQSGLNAFSTGLLDSNTGVAVFLFGFIKRLLIPFGLHHIFHAP
FWFEFGSWKNAAGEIIHGDQRIFIEQIREGAHLTAGKFMQGEFPVMMFGLPAAALAIYHTAKPENKKVVAGLMGSAALTS
FLTGITEPLEFSFLFVAPLLFFIHAVLDGLSFLTLYLLDLHLGYTFSGGFIDYFLLGILPNKTQWWLVIPVGLVYAVIYY
FVFRFLIVKLKYKTPGREDKQSQAATASATELPYAVLEAMGGKANIKHLDACITRLRVEVNDKSKVDVPGLKDLGASGVL
EVGNNMQAIFGPKSDQIKHEMQQIMNGQVVENPTTMEDDKDETVVVAEDKSATSELSHIVHAPLTGEVTPLSEVPDQVFS
EKMMGDGIAIKPSQGEVRAPFNGKVQMIFPTKHAIGLVSDSGLELLIHIGLDTVKLNGEGFTLHVEEGQEVKQGDLLINF
DLDYIRNHAKSDITPIIVTQGNITNLDFKQGEHGNISFGDQLFEAK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787343, Length=501, Percent_Identity=49.500998003992, Blast_Score=441, Evalue=1e-124,
Organism=Escherichia coli, GI1786894, Length=669, Percent_Identity=38.7144992526158, Blast_Score=410, Evalue=1e-115,
Organism=Escherichia coli, GI1787908, Length=521, Percent_Identity=37.0441458733205, Blast_Score=322, Evalue=4e-89,
Organism=Escherichia coli, GI1788757, Length=143, Percent_Identity=48.2517482517483, Blast_Score=133, Evalue=4e-32,
Organism=Escherichia coli, GI1790159, Length=123, Percent_Identity=46.3414634146341, Blast_Score=125, Evalue=9e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 74439; Mature: 74439

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVGQVRKKLFGQLQRIGKALMLPVAILPAAGLLLAIGTAMQGESLQHYLPFIQNGGVQT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHH
VAKLMTGAGGIIFDNLPMIFALGVAIGLAGGDGVAAIAAFVGYIIMNKTMGDFLQVTPKN
HHHHHHCCCCEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHEECCCC
IGDPASGYASILGIPTLQTGVFGGIIIGALAAWCYNKFYNINLPSYLGFFAGKRFVPIMM
CCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHH
ATTSFILAFPMALIWPTIQSGLNAFSTGLLDSNTGVAVFLFGFIKRLLIPFGLHHIFHAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
FWFEFGSWKNAAGEIIHGDQRIFIEQIREGAHLTAGKFMQGEFPVMMFGLPAAALAIYHT
CEEECCCCCCCCCCEEECCHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCHHHHHHHCC
AKPENKKVVAGLMGSAALTSFLTGITEPLEFSFLFVAPLLFFIHAVLDGLSFLTLYLLDL
CCCCCCEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLGYTFSGGFIDYFLLGILPNKTQWWLVIPVGLVYAVIYYFVFRFLIVKLKYKTPGREDK
HHCCEECCHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHEEECCCCCCCCH
QSQAATASATELPYAVLEAMGGKANIKHLDACITRLRVEVNDKSKVDVPGLKDLGASGVL
HHHHHCCCHHHCCHHHHHHCCCCCCHHHHHHHHHHHEEEECCCCCCCCCCHHHCCCCCHH
EVGNNMQAIFGPKSDQIKHEMQQIMNGQVVENPTTMEDDKDETVVVAEDKSATSELSHIV
HCCCCCEEEECCCHHHHHHHHHHHHCCEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHH
HAPLTGEVTPLSEVPDQVFSEKMMGDGIAIKPSQGEVRAPFNGKVQMIFPTKHAIGLVSD
CCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCEECCCCCEEEEEECCCHHEEEECC
SGLELLIHIGLDTVKLNGEGFTLHVEEGQEVKQGDLLINFDLDYIRNHAKSDITPIIVTQ
CCCEEEEEECCEEEEECCCEEEEEECCCCCCCCCCEEEEECHHHHHHHHCCCCCEEEEEC
GNITNLDFKQGEHGNISFGDQLFEAK
CCEEECCCCCCCCCCCCCCCHHHCCC
>Mature Secondary Structure
MEVGQVRKKLFGQLQRIGKALMLPVAILPAAGLLLAIGTAMQGESLQHYLPFIQNGGVQT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHH
VAKLMTGAGGIIFDNLPMIFALGVAIGLAGGDGVAAIAAFVGYIIMNKTMGDFLQVTPKN
HHHHHHCCCCEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHEECCCC
IGDPASGYASILGIPTLQTGVFGGIIIGALAAWCYNKFYNINLPSYLGFFAGKRFVPIMM
CCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHH
ATTSFILAFPMALIWPTIQSGLNAFSTGLLDSNTGVAVFLFGFIKRLLIPFGLHHIFHAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
FWFEFGSWKNAAGEIIHGDQRIFIEQIREGAHLTAGKFMQGEFPVMMFGLPAAALAIYHT
CEEECCCCCCCCCCEEECCHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCHHHHHHHCC
AKPENKKVVAGLMGSAALTSFLTGITEPLEFSFLFVAPLLFFIHAVLDGLSFLTLYLLDL
CCCCCCEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLGYTFSGGFIDYFLLGILPNKTQWWLVIPVGLVYAVIYYFVFRFLIVKLKYKTPGREDK
HHCCEECCHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHEEECCCCCCCCH
QSQAATASATELPYAVLEAMGGKANIKHLDACITRLRVEVNDKSKVDVPGLKDLGASGVL
HHHHHCCCHHHCCHHHHHHCCCCCCHHHHHHHHHHHEEEECCCCCCCCCCHHHCCCCCHH
EVGNNMQAIFGPKSDQIKHEMQQIMNGQVVENPTTMEDDKDETVVVAEDKSATSELSHIV
HCCCCCEEEECCCHHHHHHHHHHHHCCEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHH
HAPLTGEVTPLSEVPDQVFSEKMMGDGIAIKPSQGEVRAPFNGKVQMIFPTKHAIGLVSD
CCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCEECCCCCEEEEEECCCHHEEEECC
SGLELLIHIGLDTVKLNGEGFTLHVEEGQEVKQGDLLINFDLDYIRNHAKSDITPIIVTQ
CCCEEEEEECCEEEEECCCEEEEEECCCCCCCCCCEEEEECHHHHHHHHCCCCCEEEEEC
GNITNLDFKQGEHGNISFGDQLFEAK
CCEEECCCCCCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA