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The map label for this gene is ispG [H]

Identifier: 160903370

GI number: 160903370

Start: 2151942

End: 2152991

Strand: Direct

Name: ispG [H]

Synonym: Pmob_1941

Alternate gene names: 160903370

Gene position: 2151942-2152991 (Clockwise)

Preceding gene: 160903369

Following gene: 160903371

Centisome position: 99.19

GC content: 37.71

Gene sequence:

>1050_bases
ATGTTCTCAGAAAAAGTAGTGGATGTTGGCGGGGTTAAAATTGGTGGGAAGTATCCCATCGTTATTCAAAGTATGACGAA
TACGGATACCGCTAATATTGAGCAAACATTGTTTCAAGTTGAACGATTGAAAAATTCAGGTGCCCAGATTGTAAGGGTAT
CGGTGAGAAGTAAGGATGACATTCAACCTTTTGGTGAAATCGTTAAGAAATCCCAAGTGCCTTTAGTTGCAGATATTCAT
TTTGACTACAGGTTAGCTATAGAATCTATTAAGGCCGGTGCTTCGAAAGTAAGAATAAACCCAGGCAACATTGGTTCAGA
TGTTAAAATACGAGAAATAGTTAAAGTTGCTAAAGAGTACAACGTCCCAATAAGGGTCGGATCTAATTCTGGTTCGATCG
CTAAGGAATTTTCTGATTTACCTAGACATAAAGCATTGGCTGAAAGCGCTTTAAAAGAAGTTCGATTGCTAGAAAAAGAA
GGTTTTTACGATATTGTCGTCTCTGTGAAATCTGTTGATGCTAAAGAAACTTTTGTTGCCAATCAATATCTTTCGAGGTT
GATACCTTATCCTTTTCATATAGGAGTTACTGAAGCAGGTGTGTTTGAGGATGCAGTTATATTGTCATCAGCAGGTTTAG
GTTCTTTGCTTATAAACGACATCGGAGATACAATCAGAATATCCATCAGCGGGGATCCGATCAGAGAAGTTGAATTGGCA
AAAGATTTGCTAATAGCATTAGGCTTGAAAATAGGGGTAAGAGTAATAGCCTGTCCGACTTGTGCAAGGACGGAAATCGA
CGTTGAAGGATTAGCCTACGAAGTAAAAAAAATGTTAAAAGGTAAAGAGGTTAAAAAAAATATTACCGTAGCGGTCATGG
GATGTGTTGTTAACGGTCCTGGTGAAGCTAAACACTCTGATATCGCCATAGTTGGAACCAAAAATTCATCAGCGGCTATT
TTCCTTAAAGGGGAACTTTTCGGTACTTTTAAGAGAAGTGAGATAAGAGAGAAACTTTTTGAGATTATAGAAGAAATTCA
GAATTCTTAA

Upstream 100 bases:

>100_bases
GAGGCTATAGTGAATACGATAGGATTTTTATTCTTAATATTTTTGATGATCTTCGTCACTTATAACGATATAATGAGATT
TTTCTAATGAGGTGTTCTAA

Downstream 100 bases:

>100_bases
TTAAAGAAGGGAATACTATGGAGATAGATCCCATTACCGGAAAAAAAATGGATAAAGAGATGAAAAAAAAGAAGATAAAA
AAATCTAACGATCAAGATGT

Product: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase

Products: NA

Alternate protein names: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MFSEKVVDVGGVKIGGKYPIVIQSMTNTDTANIEQTLFQVERLKNSGAQIVRVSVRSKDDIQPFGEIVKKSQVPLVADIH
FDYRLAIESIKAGASKVRINPGNIGSDVKIREIVKVAKEYNVPIRVGSNSGSIAKEFSDLPRHKALAESALKEVRLLEKE
GFYDIVVSVKSVDAKETFVANQYLSRLIPYPFHIGVTEAGVFEDAVILSSAGLGSLLINDIGDTIRISISGDPIREVELA
KDLLIALGLKIGVRVIACPTCARTEIDVEGLAYEVKKMLKGKEVKKNITVAVMGCVVNGPGEAKHSDIAIVGTKNSSAAI
FLKGELFGTFKRSEIREKLFEIIEEIQNS

Sequences:

>Translated_349_residues
MFSEKVVDVGGVKIGGKYPIVIQSMTNTDTANIEQTLFQVERLKNSGAQIVRVSVRSKDDIQPFGEIVKKSQVPLVADIH
FDYRLAIESIKAGASKVRINPGNIGSDVKIREIVKVAKEYNVPIRVGSNSGSIAKEFSDLPRHKALAESALKEVRLLEKE
GFYDIVVSVKSVDAKETFVANQYLSRLIPYPFHIGVTEAGVFEDAVILSSAGLGSLLINDIGDTIRISISGDPIREVELA
KDLLIALGLKIGVRVIACPTCARTEIDVEGLAYEVKKMLKGKEVKKNITVAVMGCVVNGPGEAKHSDIAIVGTKNSSAAI
FLKGELFGTFKRSEIREKLFEIIEEIQNS
>Mature_349_residues
MFSEKVVDVGGVKIGGKYPIVIQSMTNTDTANIEQTLFQVERLKNSGAQIVRVSVRSKDDIQPFGEIVKKSQVPLVADIH
FDYRLAIESIKAGASKVRINPGNIGSDVKIREIVKVAKEYNVPIRVGSNSGSIAKEFSDLPRHKALAESALKEVRLLEKE
GFYDIVVSVKSVDAKETFVANQYLSRLIPYPFHIGVTEAGVFEDAVILSSAGLGSLLINDIGDTIRISISGDPIREVELA
KDLLIALGLKIGVRVIACPTCARTEIDVEGLAYEVKKMLKGKEVKKNITVAVMGCVVNGPGEAKHSDIAIVGTKNSSAAI
FLKGELFGTFKRSEIREKLFEIIEEIQNS

Specific function: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate [H]

COG id: COG0821

COG function: function code I; Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispG family [H]

Homologues:

Organism=Escherichia coli, GI1788863, Length=313, Percent_Identity=42.1725239616613, Blast_Score=244, Evalue=5e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011005
- InterPro:   IPR016425
- InterPro:   IPR004588 [H]

Pfam domain/function: PF04551 GcpE [H]

EC number: =1.17.7.1 [H]

Molecular weight: Translated: 37984; Mature: 37984

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSEKVVDVGGVKIGGKYPIVIQSMTNTDTANIEQTLFQVERLKNSGAQIVRVSVRSKDD
CCCCCEEECCCEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCC
IQPFGEIVKKSQVPLVADIHFDYRLAIESIKAGASKVRINPGNIGSDVKIREIVKVAKEY
CCHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHC
NVPIRVGSNSGSIAKEFSDLPRHKALAESALKEVRLLEKEGFYDIVVSVKSVDAKETFVA
CCCEEECCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHH
NQYLSRLIPYPFHIGVTEAGVFEDAVILSSAGLGSLLINDIGDTIRISISGDPIREVELA
HHHHHHHCCCCEEECCCCCCCHHHHHEEECCCCHHHHHHCCCCEEEEEECCCCCHHHHHH
KDLLIALGLKIGVRVIACPTCARTEIDVEGLAYEVKKMLKGKEVKKNITVAVMGCVVNGP
HHHHHHHHHHHCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHCCEEEEEEEEEECCC
GEAKHSDIAIVGTKNSSAAIFLKGELFGTFKRSEIREKLFEIIEEIQNS
CCCCCCCEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFSEKVVDVGGVKIGGKYPIVIQSMTNTDTANIEQTLFQVERLKNSGAQIVRVSVRSKDD
CCCCCEEECCCEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCC
IQPFGEIVKKSQVPLVADIHFDYRLAIESIKAGASKVRINPGNIGSDVKIREIVKVAKEY
CCHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHC
NVPIRVGSNSGSIAKEFSDLPRHKALAESALKEVRLLEKEGFYDIVVSVKSVDAKETFVA
CCCEEECCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHH
NQYLSRLIPYPFHIGVTEAGVFEDAVILSSAGLGSLLINDIGDTIRISISGDPIREVELA
HHHHHHHCCCCEEECCCCCCCHHHHHEEECCCCHHHHHHCCCCEEEEEECCCCCHHHHHH
KDLLIALGLKIGVRVIACPTCARTEIDVEGLAYEVKKMLKGKEVKKNITVAVMGCVVNGP
HHHHHHHHHHHCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHCCEEEEEEEEEECCC
GEAKHSDIAIVGTKNSSAAIFLKGELFGTFKRSEIREKLFEIIEEIQNS
CCCCCCCEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA