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The map label for this gene is dtd

Identifier: 160903363

GI number: 160903363

Start: 2140614

End: 2141066

Strand: Direct

Name: dtd

Synonym: Pmob_1934

Alternate gene names: 160903363

Gene position: 2140614-2141066 (Clockwise)

Preceding gene: 160903362

Following gene: 160903364

Centisome position: 98.67

GC content: 33.55

Gene sequence:

>453_bases
TTGAGGGCAGTGGTTCAAAGAGTATCACAAGCTTCCGTAACCATTTCTGATAACATTGTTGCTCAAATAGAAAAAGGTCT
CCTGGTTTTCTTGGGCATTTCGAAAATTGATCAAGTATCAGATATTAGTTGGATGGCTGATAAGATTGTAAATCTTAGAA
TTTTTGAAGATGATCAAAATAAAATGAATAGATCTTTATTAGATATTATGGGGGATATGATCGTTGTCTCTCAATTCACT
TTATATGGTGATTGTAGAAAAGGAAGGAGACCATCCTTCACTGATTCGGCAACTCCTGAGAAAGCTAAAGTTCTTTACGA
TAATTTTCTTTCCTATCTTAAAGAAAAATACCCTATAAACGTTCAACAAGGTGAGTTTCAAGCTCATATGAAAGTAAATA
TTGTCAACGATGGTCCAGTGACTTTACTTTTAGATTCTCAAAAGTTGTTTTGA

Upstream 100 bases:

>100_bases
ATTAGGATATATTTAGCTGTTCAGAATTTAAAGCATCTGAGTCTTTTGAGTAATAAATTGAAAAATTCTAAAGGTGTTTA
TTCTGTTAGGAGGGTATAAT

Downstream 100 bases:

>100_bases
ATTTAACAAATATCTTTGATTGGAGGGATTTTATGAAAGAGTTAGAAGTTACCGTTTTTGTCTACAACGAAGATCCTTTT
GAAGCACACATTTCATCGGA

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MRAVVQRVSQASVTISDNIVAQIEKGLLVFLGISKIDQVSDISWMADKIVNLRIFEDDQNKMNRSLLDIMGDMIVVSQFT
LYGDCRKGRRPSFTDSATPEKAKVLYDNFLSYLKEKYPINVQQGEFQAHMKVNIVNDGPVTLLLDSQKLF

Sequences:

>Translated_150_residues
MRAVVQRVSQASVTISDNIVAQIEKGLLVFLGISKIDQVSDISWMADKIVNLRIFEDDQNKMNRSLLDIMGDMIVVSQFT
LYGDCRKGRRPSFTDSATPEKAKVLYDNFLSYLKEKYPINVQQGEFQAHMKVNIVNDGPVTLLLDSQKLF
>Mature_150_residues
MRAVVQRVSQASVTISDNIVAQIEKGLLVFLGISKIDQVSDISWMADKIVNLRIFEDDQNKMNRSLLDIMGDMIVVSQFT
LYGDCRKGRRPSFTDSATPEKAKVLYDNFLSYLKEKYPINVQQGEFQAHMKVNIVNDGPVTLLLDSQKLF

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=149, Percent_Identity=42.9530201342282, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1790320, Length=144, Percent_Identity=42.3611111111111, Blast_Score=129, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI115533292, Length=150, Percent_Identity=40, Blast_Score=116, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6319982, Length=148, Percent_Identity=37.8378378378378, Blast_Score=108, Evalue=4e-25,
Organism=Drosophila melanogaster, GI281361569, Length=147, Percent_Identity=41.4965986394558, Blast_Score=117, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_PETMO (A9BIE9)

Other databases:

- EMBL:   CP000879
- RefSeq:   YP_001568944.1
- ProteinModelPortal:   A9BIE9
- SMR:   A9BIE9
- GeneID:   5757218
- GenomeReviews:   CP000879_GR
- KEGG:   pmo:Pmob_1934
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- BioCyc:   PMOB403833:PMOB_1934-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 17019; Mature: 17019

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVVQRVSQASVTISDNIVAQIEKGLLVFLGISKIDQVSDISWMADKIVNLRIFEDDQN
CCHHHHHHHHCEEEECCHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHEEEEEEECCHH
KMNRSLLDIMGDMIVVSQFTLYGDCRKGRRPSFTDSATPEKAKVLYDNFLSYLKEKYPIN
HHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
VQQGEFQAHMKVNIVNDGPVTLLLDSQKLF
CCCCCEEEEEEEEEECCCCEEEEECCCCCC
>Mature Secondary Structure
MRAVVQRVSQASVTISDNIVAQIEKGLLVFLGISKIDQVSDISWMADKIVNLRIFEDDQN
CCHHHHHHHHCEEEECCHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHEEEEEEECCHH
KMNRSLLDIMGDMIVVSQFTLYGDCRKGRRPSFTDSATPEKAKVLYDNFLSYLKEKYPIN
HHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
VQQGEFQAHMKVNIVNDGPVTLLLDSQKLF
CCCCCEEEEEEEEEECCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA