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The map label for this gene is yggV [C]

Identifier: 160903338

GI number: 160903338

Start: 2114192

End: 2114815

Strand: Direct

Name: yggV [C]

Synonym: Pmob_1909

Alternate gene names: 160903338

Gene position: 2114192-2114815 (Clockwise)

Preceding gene: 160903337

Following gene: 160903339

Centisome position: 97.45

GC content: 31.57

Gene sequence:

>624_bases
TTGAGTGACGTCTATTTGGCTACATCAAACAGAAACAAGGTAAGAGAAATCAATGAAATCTTGCAAAATATTGATATAAA
TGGAAGTATCAATGTTAAATATATATTTGATGAGATAAAAGAGGATAATTTTGAAGTAGAAGAGTACGGCGAAACTTATG
TAGAAAATTCTGTTATTAAAGCTTGGGCTTATTCAAAATTAATAAAAAAACCAGTTTTTTCAGATGATTCTGGTTTGTCT
ATAATCTCTCTCGGAGGATTTCCTGGCGTGAACTCTGCAAGGTTCATGGAAAATCATTCCTATGAGCAAAAGATGAAGGA
ATTATTATCAATGCTGGAAAATGAAAAAGATAGAACCGCTTATTTTGCCTGTGCGGCGACGTATTTTGACCCTCAAAAAA
ATATTTTAGTTACTTGTCAAGAAGAAGTTTATGGTAAAATAGCATTTGAGATAAGAGGAAAGAATGGTTTCGGTTACGAT
CCTATTTTTATTCCCGATGGATACGATTATACATTTGGAGAACTGACCAAAGACGTAAAAAATAGCATAAGTCATAGGGC
AAAGGCTATAAAAAAGTTGCTTCTTTTTTTAAAAAGTGCTAAAATATTAGAAAATAAAGAGTAA

Upstream 100 bases:

>100_bases
CACCAAAGTGGCGTTAACACTTTTATCATTGGTGCCAGTGTGTTTTATTCAGAAAATCCTTCACAAGAGATAATCGAACT
AAAAAAGGTGGCAGAAGATT

Downstream 100 bases:

>100_bases
TTTTTCATAATATTGATTCAAAAGTGGATATTTTTTTGGTTTTATGGTATAATTTCGTTGAAGTTCCGTAGAATCAGGAT
TTAAGAATCTTTATCTGTTG

Product: RdgB/HAM1 family non-canonical purine NTP pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MSDVYLATSNRNKVREINEILQNIDINGSINVKYIFDEIKEDNFEVEEYGETYVENSVIKAWAYSKLIKKPVFSDDSGLS
IISLGGFPGVNSARFMENHSYEQKMKELLSMLENEKDRTAYFACAATYFDPQKNILVTCQEEVYGKIAFEIRGKNGFGYD
PIFIPDGYDYTFGELTKDVKNSISHRAKAIKKLLLFLKSAKILENKE

Sequences:

>Translated_207_residues
MSDVYLATSNRNKVREINEILQNIDINGSINVKYIFDEIKEDNFEVEEYGETYVENSVIKAWAYSKLIKKPVFSDDSGLS
IISLGGFPGVNSARFMENHSYEQKMKELLSMLENEKDRTAYFACAATYFDPQKNILVTCQEEVYGKIAFEIRGKNGFGYD
PIFIPDGYDYTFGELTKDVKNSISHRAKAIKKLLLFLKSAKILENKE
>Mature_206_residues
SDVYLATSNRNKVREINEILQNIDINGSINVKYIFDEIKEDNFEVEEYGETYVENSVIKAWAYSKLIKKPVFSDDSGLSI
ISLGGFPGVNSARFMENHSYEQKMKELLSMLENEKDRTAYFACAATYFDPQKNILVTCQEEVYGKIAFEIRGKNGFGYDP
IFIPDGYDYTFGELTKDVKNSISHRAKAIKKLLLFLKSAKILENKE

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=192, Percent_Identity=29.6875, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI31657144, Length=151, Percent_Identity=33.112582781457, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1789324, Length=208, Percent_Identity=36.0576923076923, Blast_Score=120, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI17556833, Length=194, Percent_Identity=34.020618556701, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6322529, Length=202, Percent_Identity=30.6930693069307, Blast_Score=68, Evalue=8e-13,
Organism=Drosophila melanogaster, GI19920712, Length=194, Percent_Identity=27.8350515463918, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 23725; Mature: 23594

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVYLATSNRNKVREINEILQNIDINGSINVKYIFDEIKEDNFEVEEYGETYVENSVIK
CCCEEEEECCCHHHHHHHHHHHCCCCCCCEEEEEEEHHHCCCCCCHHHHHHHHHHHHHHH
AWAYSKLIKKPVFSDDSGLSIISLGGFPGVNSARFMENHSYEQKMKELLSMLENEKDRTA
HHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCCE
YFACAATYFDPQKNILVTCQEEVYGKIAFEIRGKNGFGYDPIFIPDGYDYTFGELTKDVK
EEEEEEHEECCCCCEEEEECHHHCEEEEEEEECCCCCCCCCEECCCCCCCCHHHHHHHHH
NSISHRAKAIKKLLLFLKSAKILENKE
HHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SDVYLATSNRNKVREINEILQNIDINGSINVKYIFDEIKEDNFEVEEYGETYVENSVIK
CCEEEEECCCHHHHHHHHHHHCCCCCCCEEEEEEEHHHCCCCCCHHHHHHHHHHHHHHH
AWAYSKLIKKPVFSDDSGLSIISLGGFPGVNSARFMENHSYEQKMKELLSMLENEKDRTA
HHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCCE
YFACAATYFDPQKNILVTCQEEVYGKIAFEIRGKNGFGYDPIFIPDGYDYTFGELTKDVK
EEEEEEHEECCCCCEEEEECHHHCEEEEEEEECCCCCCCCCEECCCCCCCCHHHHHHHHH
NSISHRAKAIKKLLLFLKSAKILENKE
HHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]