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The map label for this gene is pgcA [H]

Identifier: 160903193

GI number: 160903193

Start: 1926772

End: 1928505

Strand: Direct

Name: pgcA [H]

Synonym: Pmob_1761

Alternate gene names: 160903193

Gene position: 1926772-1928505 (Clockwise)

Preceding gene: 160903192

Following gene: 160903194

Centisome position: 88.81

GC content: 33.39

Gene sequence:

>1734_bases
TTGAGAGATTACAAAAAAATCTACTACGAGTGGTTAAATAATCCATATATTGATGAAAGAGCAAAAGAAGAATTAAAAAG
TATTGAAAACAATCCTGAAGAGATAAAAGAAAGATTCTACAAAGATCTCGAGTTTGGAACAGCTGGATTGAGAGGAAAAC
TGGGTATAGGTTCGAATATGATGAATATATACACTGTGGGCAGAGCATCTCAAGCCCTTGCTGATTATATAACAGACTTT
GGTGAAGAAAGGATGAAGATGGGTGTTGTGATAGCCTACGACGTACGCCACTTTTCAAAGGAGTTTGCAAAAGAATCTGC
ATTAATCCTTGCGGCTAATGGTATAAAAACTTACTTATTTGACGATATTAGGCCTACGCCCGTTTTATCCTTTGCTGTCA
GATATCTGAAAACTACTGCTGGAATAGTCGTTACCGCTAGTCACAATCCGAAAGATTACAACGGTTACAAGGTTTATTGG
GATCAAGGGTCTCAAATATTAGATGATGTTGCCAATGGAATAATAGAAAAGATCGAAAAAATAGGATACGATTTTAGTAA
AATAAAAAAAATAAGCGAAGAAGAAGCGCTTAACAAGAATTTACTTCAATACATTTCAAAAGAAGTCGATGAAGAATACA
TTCAAAGAGTGGAAGGTTTGGCGTTAAGGGACGAAGATTTAGATAAAAATATAAAAATAGTTTACACACCTTTGAATGGA
ACATCAAATAATTTTGTCAGAAGGGTACTTAAAGATAGAGGTTTTAAAAATGTATTCATAGTTAAAGAACAAGAACTACC
CGATCCAGATTTCAAAAGCGTTGCCAACCCAAATCCAGAATACGAAGTAGCTTTTGAAGAGGCAAAAAAATTAGGTTATG
AAAAAAATGCCCAATTACTTTTAGCAAATGATCCCGATGGAGATAGAACCGCTTTAGAAATTTTAGATGGCAACAATTAC
AAAATGTTAAACGGTAACCAAGTTGGAGCCCTTTTGGTTAATTACATACTAGAAAGCAAGAGTAAAAAAGGTAGTTTGGA
AGAAAACTCTGTTATCATAAAATCGATAGTTACGGGAGATCTCACAAAAAGGATTGCAAAAAAATATGGTGTATCCGTTC
TTGAAACACTTACTGGATTTAAAAATATTTGTGGAAAAGAAAACGAATTAGAAAAAGAAGGTAAGAGTAAGTTTCTCTTT
GGTTTCGAAGAAAGTATTGGTTATATATACGGCACCTTTGTGAGAGATAAGGATGGAACTATTGCCTCTATGCTTATATC
AGAGATGGTTGGATACTACTCTAAAAAAAATAAGAATTTAATTGAGGTATTAGAAGATATTTATCAGGAGTATGGTTACG
AGTTGGAAAACAATTATTCTCTTGTGCTTGAAGGAGTTGAAGGCCAAGAAAGAATTAAAAGGATAATGGAGAAATTCAGA
AACAACTTTCCCAAAGAAATGGGGGATCTCAAACTTGAACAATACGCGGATTATTTAAAAAGAAAAATATACAATTTAAC
AACAGGTGAAATTAACGATATAACCGATATACCTTCTTCTGATGTTTTAAGATTCTGGTTTAGCGATGGTTCATGGTATG
CAATTAGGCCCTCCGGTACTGAACCAAAACTTAAAATATACATATATTCAAACGATAAAGAAAAAGAAAAATCAAAAGCA
AAACTCGATCTGATTAGAAATACCGTTGATAGCATCATAGAACATGTTGTTTAG

Upstream 100 bases:

>100_bases
TTAAATGTCTTACTATTGAAAGTTTTAGAAAATAGTCAAATGCTTGCTTTTACAGTTTCCAAAAATAGTAAAAAACCCAA
AACTAAGGAGGAAATTAAAT

Downstream 100 bases:

>100_bases
CGTTTCACACCTTATTGGGGGAAAAAACTATGATGGATATAGATAATACATCAGACTCTATAAAAGATAAAGACAAAATC
GAAGGATATATCTCAGAATT

Product: phosphoglucomutase/phosphomannomutase alpha/beta/subunit

Products: NA

Alternate protein names: PGM; Alpha-phosphoglucomutase; Glucose phosphomutase [H]

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MRDYKKIYYEWLNNPYIDERAKEELKSIENNPEEIKERFYKDLEFGTAGLRGKLGIGSNMMNIYTVGRASQALADYITDF
GEERMKMGVVIAYDVRHFSKEFAKESALILAANGIKTYLFDDIRPTPVLSFAVRYLKTTAGIVVTASHNPKDYNGYKVYW
DQGSQILDDVANGIIEKIEKIGYDFSKIKKISEEEALNKNLLQYISKEVDEEYIQRVEGLALRDEDLDKNIKIVYTPLNG
TSNNFVRRVLKDRGFKNVFIVKEQELPDPDFKSVANPNPEYEVAFEEAKKLGYEKNAQLLLANDPDGDRTALEILDGNNY
KMLNGNQVGALLVNYILESKSKKGSLEENSVIIKSIVTGDLTKRIAKKYGVSVLETLTGFKNICGKENELEKEGKSKFLF
GFEESIGYIYGTFVRDKDGTIASMLISEMVGYYSKKNKNLIEVLEDIYQEYGYELENNYSLVLEGVEGQERIKRIMEKFR
NNFPKEMGDLKLEQYADYLKRKIYNLTTGEINDITDIPSSDVLRFWFSDGSWYAIRPSGTEPKLKIYIYSNDKEKEKSKA
KLDLIRNTVDSIIEHVV

Sequences:

>Translated_577_residues
MRDYKKIYYEWLNNPYIDERAKEELKSIENNPEEIKERFYKDLEFGTAGLRGKLGIGSNMMNIYTVGRASQALADYITDF
GEERMKMGVVIAYDVRHFSKEFAKESALILAANGIKTYLFDDIRPTPVLSFAVRYLKTTAGIVVTASHNPKDYNGYKVYW
DQGSQILDDVANGIIEKIEKIGYDFSKIKKISEEEALNKNLLQYISKEVDEEYIQRVEGLALRDEDLDKNIKIVYTPLNG
TSNNFVRRVLKDRGFKNVFIVKEQELPDPDFKSVANPNPEYEVAFEEAKKLGYEKNAQLLLANDPDGDRTALEILDGNNY
KMLNGNQVGALLVNYILESKSKKGSLEENSVIIKSIVTGDLTKRIAKKYGVSVLETLTGFKNICGKENELEKEGKSKFLF
GFEESIGYIYGTFVRDKDGTIASMLISEMVGYYSKKNKNLIEVLEDIYQEYGYELENNYSLVLEGVEGQERIKRIMEKFR
NNFPKEMGDLKLEQYADYLKRKIYNLTTGEINDITDIPSSDVLRFWFSDGSWYAIRPSGTEPKLKIYIYSNDKEKEKSKA
KLDLIRNTVDSIIEHVV
>Mature_577_residues
MRDYKKIYYEWLNNPYIDERAKEELKSIENNPEEIKERFYKDLEFGTAGLRGKLGIGSNMMNIYTVGRASQALADYITDF
GEERMKMGVVIAYDVRHFSKEFAKESALILAANGIKTYLFDDIRPTPVLSFAVRYLKTTAGIVVTASHNPKDYNGYKVYW
DQGSQILDDVANGIIEKIEKIGYDFSKIKKISEEEALNKNLLQYISKEVDEEYIQRVEGLALRDEDLDKNIKIVYTPLNG
TSNNFVRRVLKDRGFKNVFIVKEQELPDPDFKSVANPNPEYEVAFEEAKKLGYEKNAQLLLANDPDGDRTALEILDGNNY
KMLNGNQVGALLVNYILESKSKKGSLEENSVIIKSIVTGDLTKRIAKKYGVSVLETLTGFKNICGKENELEKEGKSKFLF
GFEESIGYIYGTFVRDKDGTIASMLISEMVGYYSKKNKNLIEVLEDIYQEYGYELENNYSLVLEGVEGQERIKRIMEKFR
NNFPKEMGDLKLEQYADYLKRKIYNLTTGEINDITDIPSSDVLRFWFSDGSWYAIRPSGTEPKLKIYIYSNDKEKEKSKA
KLDLIRNTVDSIIEHVV

Specific function: Catalyzes the interconversion between glucose-6- phosphate and alpha-glucose-1-phosphate. This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI63055049, Length=548, Percent_Identity=34.6715328467153, Blast_Score=301, Evalue=1e-81,
Organism=Homo sapiens, GI31377548, Length=598, Percent_Identity=32.2742474916388, Blast_Score=280, Evalue=3e-75,
Organism=Caenorhabditis elegans, GI71993870, Length=542, Percent_Identity=32.1033210332103, Blast_Score=228, Evalue=8e-60,
Organism=Caenorhabditis elegans, GI71993878, Length=293, Percent_Identity=33.7883959044369, Blast_Score=149, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6323934, Length=610, Percent_Identity=30.327868852459, Blast_Score=225, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6323752, Length=588, Percent_Identity=24.1496598639456, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322722, Length=578, Percent_Identity=23.1833910034602, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI20129809, Length=578, Percent_Identity=33.3910034602076, Blast_Score=266, Evalue=3e-71,
Organism=Drosophila melanogaster, GI24651977, Length=531, Percent_Identity=32.7683615819209, Blast_Score=238, Evalue=1e-62,
Organism=Drosophila melanogaster, GI24653722, Length=563, Percent_Identity=30.7282415630551, Blast_Score=226, Evalue=3e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 66261; Mature: 66261

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDYKKIYYEWLNNPYIDERAKEELKSIENNPEEIKERFYKDLEFGTAGLRGKLGIGSNM
CCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
MNIYTVGRASQALADYITDFGEERMKMGVVIAYDVRHFSKEFAKESALILAANGIKTYLF
EEEEEECCHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHCCEEEEEECCCEEEHC
DDIRPTPVLSFAVRYLKTTAGIVVTASHNPKDYNGYKVYWDQGSQILDDVANGIIEKIEK
CCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
IGYDFSKIKKISEEEALNKNLLQYISKEVDEEYIQRVEGLALRDEDLDKNIKIVYTPLNG
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCC
TSNNFVRRVLKDRGFKNVFIVKEQELPDPDFKSVANPNPEYEVAFEEAKKLGYEKNAQLL
CCHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHCCCCCCCEEHHHHHHHHCCCCCCCEEE
LANDPDGDRTALEILDGNNYKMLNGNQVGALLVNYILESKSKKGSLEENSVIIKSIVTGD
EECCCCCCCEEEEEEECCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
LTKRIAKKYGVSVLETLTGFKNICGKENELEKEGKSKFLFGFEESIGYIYGTFVRDKDGT
HHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEHHHCCCEEEEEEEECCCCH
IASMLISEMVGYYSKKNKNLIEVLEDIYQEYGYELENNYSLVLEGVEGQERIKRIMEKFR
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEECCCCEEEEECCCCHHHHHHHHHHHH
NNFPKEMGDLKLEQYADYLKRKIYNLTTGEINDITDIPSSDVLRFWFSDGSWYAIRPSGT
HCCCHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCC
EPKLKIYIYSNDKEKEKSKAKLDLIRNTVDSIIEHVV
CCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRDYKKIYYEWLNNPYIDERAKEELKSIENNPEEIKERFYKDLEFGTAGLRGKLGIGSNM
CCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
MNIYTVGRASQALADYITDFGEERMKMGVVIAYDVRHFSKEFAKESALILAANGIKTYLF
EEEEEECCHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHCCEEEEEECCCEEEHC
DDIRPTPVLSFAVRYLKTTAGIVVTASHNPKDYNGYKVYWDQGSQILDDVANGIIEKIEK
CCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
IGYDFSKIKKISEEEALNKNLLQYISKEVDEEYIQRVEGLALRDEDLDKNIKIVYTPLNG
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCC
TSNNFVRRVLKDRGFKNVFIVKEQELPDPDFKSVANPNPEYEVAFEEAKKLGYEKNAQLL
CCHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHCCCCCCCEEHHHHHHHHCCCCCCCEEE
LANDPDGDRTALEILDGNNYKMLNGNQVGALLVNYILESKSKKGSLEENSVIIKSIVTGD
EECCCCCCCEEEEEEECCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
LTKRIAKKYGVSVLETLTGFKNICGKENELEKEGKSKFLFGFEESIGYIYGTFVRDKDGT
HHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEHHHCCCEEEEEEEECCCCH
IASMLISEMVGYYSKKNKNLIEVLEDIYQEYGYELENNYSLVLEGVEGQERIKRIMEKFR
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEECCCCEEEEECCCCHHHHHHHHHHHH
NNFPKEMGDLKLEQYADYLKRKIYNLTTGEINDITDIPSSDVLRFWFSDGSWYAIRPSGT
HCCCHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCC
EPKLKIYIYSNDKEKEKSKAKLDLIRNTVDSIIEHVV
CCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 2127799 [H]