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The map label for this gene is sdhA [H]

Identifier: 160903191

GI number: 160903191

Start: 1925046

End: 1925921

Strand: Direct

Name: sdhA [H]

Synonym: Pmob_1759

Alternate gene names: 160903191

Gene position: 1925046-1925921 (Clockwise)

Preceding gene: 160903190

Following gene: 160903192

Centisome position: 88.73

GC content: 40.98

Gene sequence:

>876_bases
ATGTATAACTCTGCAAAGCAACTATTAGAACTTTGTGAAAAGCAAAAAAAGCCAATCTATCAAGTAGTTATAGAAGAAGA
ATCCAAATCATCTGGTTCAGCTCCTGAAATAATTCTTTCACAAATGAAAGAAATTTTATCTGTCATGGAGCACTCCTCTC
AAAGTACCTTGAATAAAAAGGTACCTAGTTTATCAGGAATGATGGGAGGAGATGCTCAACGGGTTAACAATTATCAAAAG
GATGGTAAAACCCTTTTAGGGGTTATTCCTAATAAAGCGATGGCTATGGCCCTTTCAACCGCAGAAGTCAATGCCTCTAT
GGGAAAAATAGTAGCAGCTCCCACTGCGGGCTCTTCTGGCATATTACCAGCAGTCTTGATGACTCTTGAGGAAAGTTTAA
ATTTGAATGAAGAGGATTTGATCCATGCCCTACTTGTAGCAGCGGGGATTGGACGAGTTATCGGTCAAAATGCAACCTTT
TCTGGTGCTGAAGGGGGATGCCAAGTAGAGTGTGGTTCAGCGGCAGCTATGGCTGCGGGAGCTGCAGTGTTTGCTTCAGA
AGGAAACAATGAACAAATCTTTCATGCAGCCTCTATTGCACTCATTAATATAATGGGGCTGGTTTGTGATCCCATTGCTG
GTTTAGTAGAATTCCCATGTATTCTGAGAAATGCTTCAGGAGCTATAAATGCCTTGTCTGCCGCAGATTTAGCTCTTGCA
GGGGTAAAATCTTTAATACCTTTTGATGAAGTGGTAAAAGCAATGTACAAAGTAGGAAAAGCTCTTCCAGAAAGCTTAAG
AGAAACAGGGCTTGGTGGTATAGCAGGTACTCCAACAGGTTGTGCTATAAAAAACTCTCTGCTTAAGAATGGTTAA

Upstream 100 bases:

>100_bases
AATATTGGATGTCCCATATCTATGTTAAAAGATGCATGCAACAATATTTACGATGCTTTTAAAAATTTATAAAAATAGAA
AAAGTAAAAGGGAGAATTTA

Downstream 100 bases:

>100_bases
ACTTTGTTACTTTCATTGCAATAATATCAGAGAGATAAAGAAAGGGATATCATATGAAAAACTTCGGTATTTTCGACGTA
ATCGGTCCCGTTATGATTGG

Product: L-serine dehydratase, iron-sulfur-dependent subunit alpha

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MYNSAKQLLELCEKQKKPIYQVVIEEESKSSGSAPEIILSQMKEILSVMEHSSQSTLNKKVPSLSGMMGGDAQRVNNYQK
DGKTLLGVIPNKAMAMALSTAEVNASMGKIVAAPTAGSSGILPAVLMTLEESLNLNEEDLIHALLVAAGIGRVIGQNATF
SGAEGGCQVECGSAAAMAAGAAVFASEGNNEQIFHAASIALINIMGLVCDPIAGLVEFPCILRNASGAINALSAADLALA
GVKSLIPFDEVVKAMYKVGKALPESLRETGLGGIAGTPTGCAIKNSLLKNG

Sequences:

>Translated_291_residues
MYNSAKQLLELCEKQKKPIYQVVIEEESKSSGSAPEIILSQMKEILSVMEHSSQSTLNKKVPSLSGMMGGDAQRVNNYQK
DGKTLLGVIPNKAMAMALSTAEVNASMGKIVAAPTAGSSGILPAVLMTLEESLNLNEEDLIHALLVAAGIGRVIGQNATF
SGAEGGCQVECGSAAAMAAGAAVFASEGNNEQIFHAASIALINIMGLVCDPIAGLVEFPCILRNASGAINALSAADLALA
GVKSLIPFDEVVKAMYKVGKALPESLRETGLGGIAGTPTGCAIKNSLLKNG
>Mature_291_residues
MYNSAKQLLELCEKQKKPIYQVVIEEESKSSGSAPEIILSQMKEILSVMEHSSQSTLNKKVPSLSGMMGGDAQRVNNYQK
DGKTLLGVIPNKAMAMALSTAEVNASMGKIVAAPTAGSSGILPAVLMTLEESLNLNEEDLIHALLVAAGIGRVIGQNATF
SGAEGGCQVECGSAAAMAAGAAVFASEGNNEQIFHAASIALINIMGLVCDPIAGLVEFPCILRNASGAINALSAADLALA
GVKSLIPFDEVVKAMYKVGKALPESLRETGLGGIAGTPTGCAIKNSLLKNG

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI48994925, Length=284, Percent_Identity=32.7464788732394, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1789161, Length=188, Percent_Identity=41.4893617021277, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1788116, Length=182, Percent_Identity=41.2087912087912, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005130
- InterPro:   IPR004642 [H]

Pfam domain/function: PF03313 SDH_alpha [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 29960; Mature: 29960

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNSAKQLLELCEKQKKPIYQVVIEEESKSSGSAPEIILSQMKEILSVMEHSSQSTLNKK
CCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
VPSLSGMMGGDAQRVNNYQKDGKTLLGVIPNKAMAMALSTAEVNASMGKIVAAPTAGSSG
CCHHHCCCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCEEECCCCCCCC
ILPAVLMTLEESLNLNEEDLIHALLVAAGIGRVIGQNATFSGAEGGCQVECGSAAAMAAG
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCHHHHHHH
AAVFASEGNNEQIFHAASIALINIMGLVCDPIAGLVEFPCILRNASGAINALSAADLALA
HHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
GVKSLIPFDEVVKAMYKVGKALPESLRETGLGGIAGTPTGCAIKNSLLKNG
HHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MYNSAKQLLELCEKQKKPIYQVVIEEESKSSGSAPEIILSQMKEILSVMEHSSQSTLNKK
CCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
VPSLSGMMGGDAQRVNNYQKDGKTLLGVIPNKAMAMALSTAEVNASMGKIVAAPTAGSSG
CCHHHCCCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCEEECCCCCCCC
ILPAVLMTLEESLNLNEEDLIHALLVAAGIGRVIGQNATFSGAEGGCQVECGSAAAMAAG
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCHHHHHHH
AAVFASEGNNEQIFHAASIALINIMGLVCDPIAGLVEFPCILRNASGAINALSAADLALA
HHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
GVKSLIPFDEVVKAMYKVGKALPESLRETGLGGIAGTPTGCAIKNSLLKNG
HHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9244285; 2065681 [H]