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The map label for this gene is ndhS [H]

Identifier: 160903170

GI number: 160903170

Start: 1901045

End: 1901518

Strand: Direct

Name: ndhS [H]

Synonym: Pmob_1735

Alternate gene names: 160903170

Gene position: 1901045-1901518 (Clockwise)

Preceding gene: 160903169

Following gene: 160903171

Centisome position: 87.62

GC content: 37.13

Gene sequence:

>474_bases
ATGAGAAAAATTGAAGTAACTCTCTATGTGAACAATACAAAAGAGACATTACAAGTGGAACCAACGGAGCGACTTCTTGA
TACTCTACGCAATCAGTTGAAATTAACAAGTGTAAAAGAAGGATGTGCAGTAGGCGAATGTGGAGCTTGTACTGTTATTT
TAAATGGTGAAGCTGTTCATTCATGTTTGATATTAACAGCTCAAATTGATGGTTATGAAGTTCTCACGACTGAGGGGTTG
GAAGTTAATGGAAAATTAGATCCAATTCAACAATCTTTTATTGATCATCAAGCCGTTCAATGTGGTTTTTGTACACCTGG
AATGATTATGTCCGCCAAGGCTTTGTTGAATAAAAATCCCAGCCCCTCAAAGGAAGAAATAAAAACTGCAATAGAAGGAA
ATCTCTGTAGATGTACTGGATATCAGCAAATAGTCGAAGCAATAGAAGCAGTCACACAAATGAAGGAAGGCTGA

Upstream 100 bases:

>100_bases
TAGATACACTCCGTCTTCCATTCTACAACACAATTGGAAGCAAAGAAACAAGCAGTGTACAAAATTGATCGAAACTTATG
TTTATGGAGGTATTCAAAAA

Downstream 100 bases:

>100_bases
TATATATGTCAAGCATATTGATTAAAAAAGCTAAAGTTATAACCACTATGAACGCTAATAAGGATCAATTGAAGGATCAC
GATATTTTAATTAAAGATAA

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: NDH; Nicotinic acid hydroxylase small FeS subunit; NAH [H]

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MRKIEVTLYVNNTKETLQVEPTERLLDTLRNQLKLTSVKEGCAVGECGACTVILNGEAVHSCLILTAQIDGYEVLTTEGL
EVNGKLDPIQQSFIDHQAVQCGFCTPGMIMSAKALLNKNPSPSKEEIKTAIEGNLCRCTGYQQIVEAIEAVTQMKEG

Sequences:

>Translated_157_residues
MRKIEVTLYVNNTKETLQVEPTERLLDTLRNQLKLTSVKEGCAVGECGACTVILNGEAVHSCLILTAQIDGYEVLTTEGL
EVNGKLDPIQQSFIDHQAVQCGFCTPGMIMSAKALLNKNPSPSKEEIKTAIEGNLCRCTGYQQIVEAIEAVTQMKEG
>Mature_157_residues
MRKIEVTLYVNNTKETLQVEPTERLLDTLRNQLKLTSVKEGCAVGECGACTVILNGEAVHSCLILTAQIDGYEVLTTEGL
EVNGKLDPIQQSFIDHQAVQCGFCTPGMIMSAKALLNKNPSPSKEEIKTAIEGNLCRCTGYQQIVEAIEAVTQMKEG

Specific function: Catalyzes the hydroxylation of nicotinate to 6- hydroxynicotinate. Also active against 2-pyrazinecarboxylic acid, but inactive against other nicotinate analogs [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=158, Percent_Identity=34.8101265822785, Blast_Score=91, Evalue=3e-19,
Organism=Homo sapiens, GI91823271, Length=165, Percent_Identity=36.969696969697, Blast_Score=89, Evalue=2e-18,
Organism=Escherichia coli, GI1789232, Length=147, Percent_Identity=47.6190476190476, Blast_Score=129, Evalue=7e-32,
Organism=Escherichia coli, GI1786480, Length=161, Percent_Identity=40.3726708074534, Blast_Score=123, Evalue=6e-30,
Organism=Escherichia coli, GI1789246, Length=147, Percent_Identity=29.9319727891156, Blast_Score=71, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17540638, Length=153, Percent_Identity=42.483660130719, Blast_Score=124, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17539860, Length=141, Percent_Identity=43.9716312056738, Blast_Score=120, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI32566215, Length=150, Percent_Identity=40, Blast_Score=117, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17737937, Length=160, Percent_Identity=38.75, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24647197, Length=144, Percent_Identity=35.4166666666667, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24647195, Length=144, Percent_Identity=35.4166666666667, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24647199, Length=138, Percent_Identity=36.231884057971, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24647201, Length=139, Percent_Identity=35.9712230215827, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24647193, Length=158, Percent_Identity=35.4430379746835, Blast_Score=81, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.17.1.5 [H]

Molecular weight: Translated: 17117; Mature: 17117

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
5.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIEVTLYVNNTKETLQVEPTERLLDTLRNQLKLTSVKEGCAVGECGACTVILNGEAVH
CCEEEEEEEECCCCCEEEECCHHHHHHHHHHHHEHHHHHCCCCCCCCCEEEEEECCHHHE
SCLILTAQIDGYEVLTTEGLEVNGKLDPIQQSFIDHQAVQCGFCTPGMIMSAKALLNKNP
EEEEEEEECCCEEEEEECCEEECCCCCHHHHHHHHHHHEEECCCCCCHHHHHHHHHCCCC
SPSKEEIKTAIEGNLCRCTGYQQIVEAIEAVTQMKEG
CCCHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRKIEVTLYVNNTKETLQVEPTERLLDTLRNQLKLTSVKEGCAVGECGACTVILNGEAVH
CCEEEEEEEECCCCCEEEECCHHHHHHHHHHHHEHHHHHCCCCCCCCCEEEEEECCHHHE
SCLILTAQIDGYEVLTTEGLEVNGKLDPIQQSFIDHQAVQCGFCTPGMIMSAKALLNKNP
EEEEEEEECCCEEEEEECCEEECCCCCHHHHHHHHHHHEEECCCCCCHHHHHHHHHCCCC
SPSKEEIKTAIEGNLCRCTGYQQIVEAIEAVTQMKEG
CCCHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA