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The map label for this gene is argD [H]

Identifier: 160903133

GI number: 160903133

Start: 1857410

End: 1858594

Strand: Direct

Name: argD [H]

Synonym: Pmob_1698

Alternate gene names: 160903133

Gene position: 1857410-1858594 (Clockwise)

Preceding gene: 160903132

Following gene: 160903134

Centisome position: 85.61

GC content: 37.05

Gene sequence:

>1185_bases
ATGATAATCTCTGAAGATAAAAAGTATGTAATGAATACTTACTCAAGATTTCCAATAACTTTGGTACAAGGGAAAGGTAC
AAAGGTGTGGGATGAAAACGGTAAAGAATACTTAGATTTTGTTGCTGGGATCGCTGTCAATGTTTTGGGCCATTCTCACC
CCGTAATTGTAGAAGCAGTGAAATCTCAAGTTGACAAATTAGTTCATGTTTCTAACCTCTATTGGAATGGTAATCAAGTA
CAGTTAGCCAAGATGATTTGTGAAAAATCTTTTGGGAAAAGTGCCTTTTTTTGCAACAGTGGAACAGAAGCGAACGAAGC
TGCGATTAAGTTAGCAAGAAAATATGGAAACACTAAATACAATGGGCGAAGGTACAAAATCATCACCGCAAAGAACTCAT
TTCATGGAAGAACCTACGGTGCATTGACGGCAACAGCCCAGCCAAAATATCACAAGAATTTCGAACCTCTATTGGAAGGA
TTTGAAAGCGTAGAGTACAACGATATAAATTCACTAAAGTCGGCTGTTGATAAAAATACATGTGCTGTAATGTTGGAGGT
TATCCAAGGTGAAGGGGGAATAAACGAAGCAAAAAATGAATATCTTCAACAAGTTAGAAAACTTTGTGATGAGAACGACC
TTCTTTTGATTTTTGACGAAGTCCAAACAGGGATAGGAAGAACTGGAAAACTTTTTGCCTATGAACATTCTGGAGTGGTA
CCCGATGTGATGACCCTTGCAAAAGCCTTAGGTGGTGGTTTCCCTATCGGTGTGCTTGTTGTGAATGAAAAAGCTGACGT
ATTTACACCAGGGGATCATGGATCAACATTTGGTGGGAACCCGTTAGCCTGTGCAGTTGGCATGGCTGTGATGAAAAACG
TTGCACAAGAATCTTTTCTGAATATGGTGAAAGAAAATGGTGAATTTTTCAAAAATCAATTATTAGCAATGAAGGAAAAA
CATTCAATAATTGACAAAGTTAAGGGAAAAGGTTTGATGATCGGAGTCAAGTTAGACATAGAAGATGGCAGTGATATAGT
AAAAAAAGCTATGGAAAAAGGACTTTTGATAAATCTTTTAAATCACAATGTTTTAAGATTCGTCCCTCCTCTTATAATCA
CAAAAGAAGAGATAGCCAAGGGTATGAATATTCTCGAAGAAGTTTTTTTAGAAATGGGGTATTAA

Upstream 100 bases:

>100_bases
AGGGCACATATAATAGATGGAAGAATTCCCCATGCCTTACTTTTAGAAATCTACACAGACAAAGGTGTGGGAACAATGAT
AGCGAAGGAGGTATACGATA

Downstream 100 bases:

>100_bases
GATGAAAGGATTTATAAAGTTAAATGATTCTACCATTTTTGAAGGAGAAATTATCAGTAAAAAAGATTTTGGACAAGGCG
AAGTTGTCTTTAACACGTCT

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MIISEDKKYVMNTYSRFPITLVQGKGTKVWDENGKEYLDFVAGIAVNVLGHSHPVIVEAVKSQVDKLVHVSNLYWNGNQV
QLAKMICEKSFGKSAFFCNSGTEANEAAIKLARKYGNTKYNGRRYKIITAKNSFHGRTYGALTATAQPKYHKNFEPLLEG
FESVEYNDINSLKSAVDKNTCAVMLEVIQGEGGINEAKNEYLQQVRKLCDENDLLLIFDEVQTGIGRTGKLFAYEHSGVV
PDVMTLAKALGGGFPIGVLVVNEKADVFTPGDHGSTFGGNPLACAVGMAVMKNVAQESFLNMVKENGEFFKNQLLAMKEK
HSIIDKVKGKGLMIGVKLDIEDGSDIVKKAMEKGLLINLLNHNVLRFVPPLIITKEEIAKGMNILEEVFLEMGY

Sequences:

>Translated_394_residues
MIISEDKKYVMNTYSRFPITLVQGKGTKVWDENGKEYLDFVAGIAVNVLGHSHPVIVEAVKSQVDKLVHVSNLYWNGNQV
QLAKMICEKSFGKSAFFCNSGTEANEAAIKLARKYGNTKYNGRRYKIITAKNSFHGRTYGALTATAQPKYHKNFEPLLEG
FESVEYNDINSLKSAVDKNTCAVMLEVIQGEGGINEAKNEYLQQVRKLCDENDLLLIFDEVQTGIGRTGKLFAYEHSGVV
PDVMTLAKALGGGFPIGVLVVNEKADVFTPGDHGSTFGGNPLACAVGMAVMKNVAQESFLNMVKENGEFFKNQLLAMKEK
HSIIDKVKGKGLMIGVKLDIEDGSDIVKKAMEKGLLINLLNHNVLRFVPPLIITKEEIAKGMNILEEVFLEMGY
>Mature_394_residues
MIISEDKKYVMNTYSRFPITLVQGKGTKVWDENGKEYLDFVAGIAVNVLGHSHPVIVEAVKSQVDKLVHVSNLYWNGNQV
QLAKMICEKSFGKSAFFCNSGTEANEAAIKLARKYGNTKYNGRRYKIITAKNSFHGRTYGALTATAQPKYHKNFEPLLEG
FESVEYNDINSLKSAVDKNTCAVMLEVIQGEGGINEAKNEYLQQVRKLCDENDLLLIFDEVQTGIGRTGKLFAYEHSGVV
PDVMTLAKALGGGFPIGVLVVNEKADVFTPGDHGSTFGGNPLACAVGMAVMKNVAQESFLNMVKENGEFFKNQLLAMKEK
HSIIDKVKGKGLMIGVKLDIEDGSDIVKKAMEKGLLINLLNHNVLRFVPPLIITKEEIAKGMNILEEVFLEMGY

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=399, Percent_Identity=35.3383458646617, Blast_Score=257, Evalue=1e-68,
Organism=Homo sapiens, GI284507298, Length=300, Percent_Identity=36.3333333333333, Blast_Score=202, Evalue=3e-52,
Organism=Homo sapiens, GI13994255, Length=448, Percent_Identity=27.0089285714286, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI37574042, Length=418, Percent_Identity=27.7511961722488, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI24119277, Length=418, Percent_Identity=26.7942583732057, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI226442705, Length=418, Percent_Identity=27.0334928229665, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI226442709, Length=383, Percent_Identity=27.4151436031332, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI188536080, Length=429, Percent_Identity=23.3100233100233, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI38679950, Length=429, Percent_Identity=23.3100233100233, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI38679946, Length=429, Percent_Identity=23.3100233100233, Blast_Score=101, Evalue=1e-21,
Organism=Escherichia coli, GI1788044, Length=380, Percent_Identity=44.4736842105263, Blast_Score=359, Evalue=1e-100,
Organism=Escherichia coli, GI1789759, Length=378, Percent_Identity=41.7989417989418, Blast_Score=333, Evalue=9e-93,
Organism=Escherichia coli, GI145693181, Length=365, Percent_Identity=37.8082191780822, Blast_Score=244, Evalue=5e-66,
Organism=Escherichia coli, GI1789016, Length=409, Percent_Identity=36.6748166259169, Blast_Score=234, Evalue=9e-63,
Organism=Escherichia coli, GI1787560, Length=391, Percent_Identity=36.8286445012788, Blast_Score=195, Evalue=4e-51,
Organism=Escherichia coli, GI1786991, Length=415, Percent_Identity=28.1927710843373, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1786349, Length=337, Percent_Identity=30.5637982195846, Blast_Score=124, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI25144271, Length=393, Percent_Identity=34.0966921119593, Blast_Score=246, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI32564660, Length=428, Percent_Identity=32.0093457943925, Blast_Score=191, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI25144274, Length=263, Percent_Identity=36.5019011406844, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI71992977, Length=432, Percent_Identity=26.8518518518519, Blast_Score=144, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI71981843, Length=178, Percent_Identity=29.7752808988764, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17541228, Length=447, Percent_Identity=24.6085011185682, Blast_Score=92, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6324432, Length=402, Percent_Identity=42.2885572139304, Blast_Score=300, Evalue=4e-82,
Organism=Saccharomyces cerevisiae, GI6323470, Length=406, Percent_Identity=35.4679802955665, Blast_Score=239, Evalue=5e-64,
Organism=Saccharomyces cerevisiae, GI6324386, Length=459, Percent_Identity=28.5403050108932, Blast_Score=128, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6321456, Length=369, Percent_Identity=24.1192411924119, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21357415, Length=399, Percent_Identity=35.0877192982456, Blast_Score=268, Evalue=4e-72,
Organism=Drosophila melanogaster, GI161085790, Length=427, Percent_Identity=30.9133489461358, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI28574759, Length=429, Percent_Identity=30.5361305361305, Blast_Score=181, Evalue=7e-46,
Organism=Drosophila melanogaster, GI21356575, Length=408, Percent_Identity=27.6960784313726, Blast_Score=145, Evalue=5e-35,
Organism=Drosophila melanogaster, GI281366494, Length=405, Percent_Identity=27.4074074074074, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24667139, Length=405, Percent_Identity=27.4074074074074, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24667143, Length=405, Percent_Identity=27.4074074074074, Blast_Score=107, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43514; Mature: 43514

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIISEDKKYVMNTYSRFPITLVQGKGTKVWDENGKEYLDFVAGIAVNVLGHSHPVIVEAV
CCCCCCHHHHHHHHCCCCEEEEECCCCEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHH
KSQVDKLVHVSNLYWNGNQVQLAKMICEKSFGKSAFFCNSGTEANEAAIKLARKYGNTKY
HHHHHHHHHHHHEEECCCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCCC
NGRRYKIITAKNSFHGRTYGALTATAQPKYHKNFEPLLEGFESVEYNDINSLKSAVDKNT
CCEEEEEEEECCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCHH
CAVMLEVIQGEGGINEAKNEYLQQVRKLCDENDLLLIFDEVQTGIGRTGKLFAYEHSGVV
HHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCCCCCEEEEECCCCC
PDVMTLAKALGGGFPIGVLVVNEKADVFTPGDHGSTFGGNPLACAVGMAVMKNVAQESFL
HHHHHHHHHHCCCCCEEEEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
NMVKENGEFFKNQLLAMKEKHSIIDKVKGKGLMIGVKLDIEDGSDIVKKAMEKGLLINLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHCCCEEEHH
NHNVLRFVPPLIITKEEIAKGMNILEEVFLEMGY
HCCHHHHCCCCEEEHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIISEDKKYVMNTYSRFPITLVQGKGTKVWDENGKEYLDFVAGIAVNVLGHSHPVIVEAV
CCCCCCHHHHHHHHCCCCEEEEECCCCEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHH
KSQVDKLVHVSNLYWNGNQVQLAKMICEKSFGKSAFFCNSGTEANEAAIKLARKYGNTKY
HHHHHHHHHHHHEEECCCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCCC
NGRRYKIITAKNSFHGRTYGALTATAQPKYHKNFEPLLEGFESVEYNDINSLKSAVDKNT
CCEEEEEEEECCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCHH
CAVMLEVIQGEGGINEAKNEYLQQVRKLCDENDLLLIFDEVQTGIGRTGKLFAYEHSGVV
HHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCCCCCEEEEECCCCC
PDVMTLAKALGGGFPIGVLVVNEKADVFTPGDHGSTFGGNPLACAVGMAVMKNVAQESFL
HHHHHHHHHHCCCCCEEEEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
NMVKENGEFFKNQLLAMKEKHSIIDKVKGKGLMIGVKLDIEDGSDIVKKAMEKGLLINLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHCCCEEEHH
NHNVLRFVPPLIITKEEIAKGMNILEEVFLEMGY
HCCHHHHCCCCEEEHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]