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The map label for this gene is argB

Identifier: 160903132

GI number: 160903132

Start: 1856524

End: 1857423

Strand: Direct

Name: argB

Synonym: Pmob_1697

Alternate gene names: 160903132

Gene position: 1856524-1857423 (Clockwise)

Preceding gene: 160903131

Following gene: 160903133

Centisome position: 85.57

GC content: 35.22

Gene sequence:

>900_bases
ATGATAAAAGTTGAAAAGTTCTCTGATGAGATATCTAAAGCGGAAGTTTTGGTTGAAGCATTACCCTACATAAAAAAATT
TGCGGGAAGTATAGCTGTTATTAAGTTTGGTGGTAACGCTATGAAAGATCCACAAATTAAATCGATGGTCGCAGAAGATA
TCGTACTTATGAAATATGTTGGGCTAAATCCTGTTATCGTTCATGGTGGGGGACCAGATATCAATAAAATGCTTGCGAGT
TTAAATATAGAAACAAAATTTGTAAATGGATTAAGGGTAACCGATGAAAAAGTTATGGAAATAGTAGAGATGGTGTTGGT
TGGTAAGATAAATAAAGAGATTACATCGTTGATAAATAAAACTGGGGGAAAGGCTGTTGGATTAAGTGGGAAAGATGCAA
ATTTATTGTTGGCAGAAAAAGATTTGTCCCAAGGGGATTTGGGTTACGTTGGTAAGGTAGTGAATGTAAATAGGGAAGTA
ATTTTGAATTTAATTGAAAAAGATTATATCCCTGTCATCGCACCTTGTGCAATTGGAAGAGATTGGAAAACTTATAACGT
TAATGCCGACATAGCGGCAGGTAAAATTGCTTCCTCTTTGAACGCGGATAAATTTGTTTTATTGACTGATGTGGAAGGCG
TTTTAAAAAACAAAGAAGATGAAGAAAGTGTGATTTCAAGACTGTCATATCGAGAAGCAAAAGACTTATTGAATTCTCAA
TTTATCACTGGCGGTATGATTCCTAAGTTAAAATGTTGTATCCAAGCCTTAGAAGATGGAGTAAAAAGGGCACATATAAT
AGATGGAAGAATTCCCCATGCCTTACTTTTAGAAATCTACACAGACAAAGGTGTGGGAACAATGATAGCGAAGGAGGTAT
ACGATAATGATAATCTCTGA

Upstream 100 bases:

>100_bases
TAAAAATTATTGTAGATTTAAAAGATGGTGAAGAGAGTGCTATTTCTTGGGGATGTGATCTTAGTTACAAATATGTAGAA
ATAAATGGAGGGTACAGAAC

Downstream 100 bases:

>100_bases
AGATAAAAAGTATGTAATGAATACTTACTCAAGATTTCCAATAACTTTGGTACAAGGGAAAGGTACAAAGGTGTGGGATG
AAAACGGTAAAGAATACTTA

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MIKVEKFSDEISKAEVLVEALPYIKKFAGSIAVIKFGGNAMKDPQIKSMVAEDIVLMKYVGLNPVIVHGGGPDINKMLAS
LNIETKFVNGLRVTDEKVMEIVEMVLVGKINKEITSLINKTGGKAVGLSGKDANLLLAEKDLSQGDLGYVGKVVNVNREV
ILNLIEKDYIPVIAPCAIGRDWKTYNVNADIAAGKIASSLNADKFVLLTDVEGVLKNKEDEESVISRLSYREAKDLLNSQ
FITGGMIPKLKCCIQALEDGVKRAHIIDGRIPHALLLEIYTDKGVGTMIAKEVYDNDNL

Sequences:

>Translated_299_residues
MIKVEKFSDEISKAEVLVEALPYIKKFAGSIAVIKFGGNAMKDPQIKSMVAEDIVLMKYVGLNPVIVHGGGPDINKMLAS
LNIETKFVNGLRVTDEKVMEIVEMVLVGKINKEITSLINKTGGKAVGLSGKDANLLLAEKDLSQGDLGYVGKVVNVNREV
ILNLIEKDYIPVIAPCAIGRDWKTYNVNADIAAGKIASSLNADKFVLLTDVEGVLKNKEDEESVISRLSYREAKDLLNSQ
FITGGMIPKLKCCIQALEDGVKRAHIIDGRIPHALLLEIYTDKGVGTMIAKEVYDNDNL
>Mature_299_residues
MIKVEKFSDEISKAEVLVEALPYIKKFAGSIAVIKFGGNAMKDPQIKSMVAEDIVLMKYVGLNPVIVHGGGPDINKMLAS
LNIETKFVNGLRVTDEKVMEIVEMVLVGKINKEITSLINKTGGKAVGLSGKDANLLLAEKDLSQGDLGYVGKVVNVNREV
ILNLIEKDYIPVIAPCAIGRDWKTYNVNADIAAGKIASSLNADKFVLLTDVEGVLKNKEDEESVISRLSYREAKDLLNSQ
FITGGMIPKLKCCIQALEDGVKRAHIIDGRIPHALLLEIYTDKGVGTMIAKEVYDNDNL

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI1789181, Length=288, Percent_Identity=26.7361111111111, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI145693208, Length=227, Percent_Identity=32.15859030837, Blast_Score=82, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6320913, Length=273, Percent_Identity=28.2051282051282, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGB_PETMO (A9BI99)

Other databases:

- EMBL:   CP000879
- RefSeq:   YP_001568713.1
- ProteinModelPortal:   A9BI99
- SMR:   A9BI99
- GeneID:   5757202
- GenomeReviews:   CP000879_GR
- KEGG:   pmo:Pmob_1697
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- ProtClustDB:   PRK00942
- BioCyc:   PMOB403833:PMOB_1697-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- PRINTS:   PR00474
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 32601; Mature: 32601

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: BINDING 92-92 BINDING 186-186

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVEKFSDEISKAEVLVEALPYIKKFAGSIAVIKFGGNAMKDPQIKSMVAEDIVLMKYV
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHC
GLNPVIVHGGGPDINKMLASLNIETKFVNGLRVTDEKVMEIVEMVLVGKINKEITSLINK
CCCEEEEECCCCCHHHHHHHCCCEEEEECCEECCHHHHHHHHHHHHHHHHHHHHHHHHHC
TGGKAVGLSGKDANLLLAEKDLSQGDLGYVGKVVNVNREVILNLIEKDYIPVIAPCAIGR
CCCCEEECCCCCCEEEEEECCCCCCCCCHHHHEECCCHHHHHHHHHHCCCCEEECCCCCC
DWKTYNVNADIAAGKIASSLNADKFVLLTDVEGVLKNKEDEESVISRLSYREAKDLLNSQ
CCEEEECCCCHHHHHHHHCCCCCCEEEEECCHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
FITGGMIPKLKCCIQALEDGVKRAHIIDGRIPHALLLEIYTDKGVGTMIAKEVYDNDNL
CCCCCCCHHHHHHHHHHHHHHHHEEEECCCCCCEEEEEECCCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MIKVEKFSDEISKAEVLVEALPYIKKFAGSIAVIKFGGNAMKDPQIKSMVAEDIVLMKYV
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHC
GLNPVIVHGGGPDINKMLASLNIETKFVNGLRVTDEKVMEIVEMVLVGKINKEITSLINK
CCCEEEEECCCCCHHHHHHHCCCEEEEECCEECCHHHHHHHHHHHHHHHHHHHHHHHHHC
TGGKAVGLSGKDANLLLAEKDLSQGDLGYVGKVVNVNREVILNLIEKDYIPVIAPCAIGR
CCCCEEECCCCCCEEEEEECCCCCCCCCHHHHEECCCHHHHHHHHHHCCCCEEECCCCCC
DWKTYNVNADIAAGKIASSLNADKFVLLTDVEGVLKNKEDEESVISRLSYREAKDLLNSQ
CCEEEECCCCHHHHHHHHCCCCCCEEEEECCHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
FITGGMIPKLKCCIQALEDGVKRAHIIDGRIPHALLLEIYTDKGVGTMIAKEVYDNDNL
CCCCCCCHHHHHHHHHHHHHHHHEEEECCCCCCEEEEEECCCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA