Click here to switch to the map view.

The map label for this gene is clpB [H]

Identifier: 160903065

GI number: 160903065

Start: 1786547

End: 1789027

Strand: Direct

Name: clpB [H]

Synonym: Pmob_1629

Alternate gene names: 160903065

Gene position: 1786547-1789027 (Clockwise)

Preceding gene: 160903060

Following gene: 160903070

Centisome position: 82.35

GC content: 35.19

Gene sequence:

>2481_bases
ATGGATGGAGGTGACTTAATGAGATTCAATCCGAATGATTTTACTGAAAAATCTTTAAAAGCATTTCAAGAAGCTCAAAA
TGTTCTAGGTTATTCAGGAGGTAATATTCTCAAACCTGAGCATTTGTTGTTAGCAATTTTAAATGTTGAAGATGAAAATG
TGGGGAAAATTTTTCAAGGTACCAATACTAATTCTATAAAAAGCAAACTTGAAGAAGCTTTATCCGAAGAAATGGGAGTT
TATTACTCAATGTCCTATGGTAGTGCACAAGGTATTTATCTATCAACTAGTTTAGCAAATGCTTTACAAATAGCTAAATC
AGAATCCGACAGGATGGGTTTTAAAAAAATTCCTTTACTAGCCTTATTGTTAGGGATTTTAAAGGAAGGTACATCTTACG
CTTCCAAACTTCTGTCTGCTTATACTACGGAAGCTTTAATTAGAGAACGGCTACAAGAGATGTTAGAAAACGGAGACGAA
GAAATAGAATCAGGTATGGGAGATCCTTTGAAAAAATTTACTGTTGATTTAACCAAAGAGGCAAAGAAAGGAAAGCTTAC
GCCTGTGATAGGAAGAGAAAAAGAAATAAATAGAATGATTGAAATATTATCAAGAAAGTCTAAAAATAATCCAGTATTAG
TTGGCGACGCTGGAGTTGGGAAAACAGCCGTAGTAGAAGGTTTAGCGCAGTTGATAGTAGATGAAAATCCTCCTTCTTAT
TTGAAAAATAAGAAAATTTTACAATTAGACATGGCCGCCTTGTTGGCAGGTTCTAAATTTAGAGGTGAATTTGAAGAAAG
GCTTAAATCAGTTATCGATACTGTAAAAGAAAAGAGCGACGAAATTATTCTTTTTATCGATGAACTTCACAATATAATAG
GGGCTGGAGTGGCTGAAGGAAATGCAATGGATGCCGCAAATATTTTGAAGCCAGCTTTAGCTAGAGGTGAAATAAAGGTT
ATTGGAGCAACAACCTATGAAGAATATAAAAAATACATTGAAAAGGACAAAGCATTAGCGAGAAGGTTTCAACCGGTGTA
TGTACAAGAACCTACCCCTGAGCAGGCTATTGAAATACTTAAGGGTATAAAAGAAACTTACGAAAAACATCATAAGGTCG
AAATATTGAATGAAGCTTTAATCGCAGCAGTTAATCTTTCTCATAGATATATTAACGACAGATTCTTACCCGATAAAGCC
ATAGATTTGATAGATGAAGCTTGTGCCAGAGTGAAGTTGAGAAACTCAGCCAAACCAGAGAAAATTAGAGAATTGGAAAA
GAAATTGTCAAAATTAGAAGAAGAGATTAATAAACTAACTTTAGAGGAAAAATATGAAGAAGCCTCCAAAAAAAAGGCAG
AGTATTTTGACCTTCAAAAGGAATTAGAACAAGCACAAAAAGCTGCTAAACGAGTACAAAGCGAAATAAGCAATGTTGTA
GATGAAGACATAATAGCCTCTTTGGTACAAGAATGGACTGGAATCCCTGTTACACGAATGGTTGAAGATGAAAAGAAAAA
ACTTGCCAACCTTGAAAACGAAATACACAAAAGACTCGTTGACCAAGATGAAGCGGTTAACACTGTTGCAGATCATATTA
AAAAGGCCAGAGCGGGATTGAAAGATCCTAAGAAACCAGTTGGTTCATTCTTGTTCCTTGGTCCAACTGGAGTAGGAAAG
ACTGAACTAGCAAAAACATTAGCCGAGATATTATTTGGTACTGAAGACGCACTCGTGAGAATAGATATGAGTGAATACAT
GGAAAAATTCAACGTTTCTAGGTTAGTAGGTGCAGCACCAGGTTACGTAGGTTTCGAACAAGGTGGACAACTAACAGAAA
TGATCAGAAGGCGACCCTATTCCGTTGTATTATTCGATGAAGTTGAAAAAGCTCATCCCGATGTATTCAACATATTGTTA
CAGATCTTAGACGATGGTAGGTTAACAGATTCTCAAGGTAGGACCGTCAATTTCAGTAATACCATCATAATACTAACTTC
CAACTTAGGTTCAGAGTTACTAAATAAAACCAAGAAAAGTGTTGGTTTTGTTGGAGAAACAGAAGAAGAATCTTATGAAA
ACACAAAAAATGAAATTATGAGCCAAGTAAAATTGGCATTTAGACCTGAGTTTATTAACAGGCTCGACGATATTATAGTT
TTCAAACCCTTGGGTATCTCCCAGATAAAGAGAATAGTCGATATAATGATTTCAAGGTTAGAAGAGAGATTGAAGGAGAA
ACATATTAGTATTCAAATAACAGAAGCAGCGAAGGACGTTATAGCAAAAGAAGGATTTGATCCAGTTTATGGGGCTAGAC
CGTTGAGAAGAGTCATAGAAAGAAAAATAGAGTCTCCTTTGGCAACTATGATCATTGAAGATACTATAAAAGAAGGAGAT
ACGGTTATAGTTGACTCAAAAGATGGTGAAAATTTAGAAATAAGAAAATCTGGAGGAGAATTATTAAAAAAGCGGGATTA
A

Upstream 100 bases:

>100_bases
TTTACATTGAAAAGGATATAATGAAAATAGAATTAGCAAATAAAAGTAACGAGTGATAAAATACTTTATTACGTAGAAAA
AAACTCCCTGAAAGGGATCT

Downstream 100 bases:

>100_bases
CATCCCGCTTTTTATTCTTCAAGTAATTCAAAGTCTTCTTTAGCTGCACCACAAACTGGGCAAGTCCAATCATCGGGCAA
ATCTTCAAAAGAGGTTCCTG

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 826; Mature: 826

Protein sequence:

>826_residues
MDGGDLMRFNPNDFTEKSLKAFQEAQNVLGYSGGNILKPEHLLLAILNVEDENVGKIFQGTNTNSIKSKLEEALSEEMGV
YYSMSYGSAQGIYLSTSLANALQIAKSESDRMGFKKIPLLALLLGILKEGTSYASKLLSAYTTEALIRERLQEMLENGDE
EIESGMGDPLKKFTVDLTKEAKKGKLTPVIGREKEINRMIEILSRKSKNNPVLVGDAGVGKTAVVEGLAQLIVDENPPSY
LKNKKILQLDMAALLAGSKFRGEFEERLKSVIDTVKEKSDEIILFIDELHNIIGAGVAEGNAMDAANILKPALARGEIKV
IGATTYEEYKKYIEKDKALARRFQPVYVQEPTPEQAIEILKGIKETYEKHHKVEILNEALIAAVNLSHRYINDRFLPDKA
IDLIDEACARVKLRNSAKPEKIRELEKKLSKLEEEINKLTLEEKYEEASKKKAEYFDLQKELEQAQKAAKRVQSEISNVV
DEDIIASLVQEWTGIPVTRMVEDEKKKLANLENEIHKRLVDQDEAVNTVADHIKKARAGLKDPKKPVGSFLFLGPTGVGK
TELAKTLAEILFGTEDALVRIDMSEYMEKFNVSRLVGAAPGYVGFEQGGQLTEMIRRRPYSVVLFDEVEKAHPDVFNILL
QILDDGRLTDSQGRTVNFSNTIIILTSNLGSELLNKTKKSVGFVGETEEESYENTKNEIMSQVKLAFRPEFINRLDDIIV
FKPLGISQIKRIVDIMISRLEERLKEKHISIQITEAAKDVIAKEGFDPVYGARPLRRVIERKIESPLATMIIEDTIKEGD
TVIVDSKDGENLEIRKSGGELLKKRD

Sequences:

>Translated_826_residues
MDGGDLMRFNPNDFTEKSLKAFQEAQNVLGYSGGNILKPEHLLLAILNVEDENVGKIFQGTNTNSIKSKLEEALSEEMGV
YYSMSYGSAQGIYLSTSLANALQIAKSESDRMGFKKIPLLALLLGILKEGTSYASKLLSAYTTEALIRERLQEMLENGDE
EIESGMGDPLKKFTVDLTKEAKKGKLTPVIGREKEINRMIEILSRKSKNNPVLVGDAGVGKTAVVEGLAQLIVDENPPSY
LKNKKILQLDMAALLAGSKFRGEFEERLKSVIDTVKEKSDEIILFIDELHNIIGAGVAEGNAMDAANILKPALARGEIKV
IGATTYEEYKKYIEKDKALARRFQPVYVQEPTPEQAIEILKGIKETYEKHHKVEILNEALIAAVNLSHRYINDRFLPDKA
IDLIDEACARVKLRNSAKPEKIRELEKKLSKLEEEINKLTLEEKYEEASKKKAEYFDLQKELEQAQKAAKRVQSEISNVV
DEDIIASLVQEWTGIPVTRMVEDEKKKLANLENEIHKRLVDQDEAVNTVADHIKKARAGLKDPKKPVGSFLFLGPTGVGK
TELAKTLAEILFGTEDALVRIDMSEYMEKFNVSRLVGAAPGYVGFEQGGQLTEMIRRRPYSVVLFDEVEKAHPDVFNILL
QILDDGRLTDSQGRTVNFSNTIIILTSNLGSELLNKTKKSVGFVGETEEESYENTKNEIMSQVKLAFRPEFINRLDDIIV
FKPLGISQIKRIVDIMISRLEERLKEKHISIQITEAAKDVIAKEGFDPVYGARPLRRVIERKIESPLATMIIEDTIKEGD
TVIVDSKDGENLEIRKSGGELLKKRD
>Mature_826_residues
MDGGDLMRFNPNDFTEKSLKAFQEAQNVLGYSGGNILKPEHLLLAILNVEDENVGKIFQGTNTNSIKSKLEEALSEEMGV
YYSMSYGSAQGIYLSTSLANALQIAKSESDRMGFKKIPLLALLLGILKEGTSYASKLLSAYTTEALIRERLQEMLENGDE
EIESGMGDPLKKFTVDLTKEAKKGKLTPVIGREKEINRMIEILSRKSKNNPVLVGDAGVGKTAVVEGLAQLIVDENPPSY
LKNKKILQLDMAALLAGSKFRGEFEERLKSVIDTVKEKSDEIILFIDELHNIIGAGVAEGNAMDAANILKPALARGEIKV
IGATTYEEYKKYIEKDKALARRFQPVYVQEPTPEQAIEILKGIKETYEKHHKVEILNEALIAAVNLSHRYINDRFLPDKA
IDLIDEACARVKLRNSAKPEKIRELEKKLSKLEEEINKLTLEEKYEEASKKKAEYFDLQKELEQAQKAAKRVQSEISNVV
DEDIIASLVQEWTGIPVTRMVEDEKKKLANLENEIHKRLVDQDEAVNTVADHIKKARAGLKDPKKPVGSFLFLGPTGVGK
TELAKTLAEILFGTEDALVRIDMSEYMEKFNVSRLVGAAPGYVGFEQGGQLTEMIRRRPYSVVLFDEVEKAHPDVFNILL
QILDDGRLTDSQGRTVNFSNTIIILTSNLGSELLNKTKKSVGFVGETEEESYENTKNEIMSQVKLAFRPEFINRLDDIIV
FKPLGISQIKRIVDIMISRLEERLKEKHISIQITEAAKDVIAKEGFDPVYGARPLRRVIERKIESPLATMIIEDTIKEGD
TVIVDSKDGENLEIRKSGGELLKKRD

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=321, Percent_Identity=33.9563862928349, Blast_Score=195, Evalue=2e-49,
Organism=Escherichia coli, GI1788943, Length=855, Percent_Identity=45.2631578947368, Blast_Score=716, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=327, Percent_Identity=42.8134556574924, Blast_Score=271, Evalue=1e-73,
Organism=Saccharomyces cerevisiae, GI6320464, Length=702, Percent_Identity=46.1538461538462, Blast_Score=600, Evalue=1e-172,
Organism=Saccharomyces cerevisiae, GI6323002, Length=890, Percent_Identity=36.2921348314607, Blast_Score=516, Evalue=1e-147,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 92544; Mature: 92544

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00870 CLPAB_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGGDLMRFNPNDFTEKSLKAFQEAQNVLGYSGGNILKPEHLLLAILNVEDENVGKIFQG
CCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHEEEEEECCCCCCCHHCCC
TNTNSIKSKLEEALSEEMGVYYSMSYGSAQGIYLSTSLANALQIAKSESDRMGFKKIPLL
CCCHHHHHHHHHHHHHHCCEEEEECCCCCCCEEEEHHHHHHHHHHHCCHHCCCHHHHHHH
ALLLGILKEGTSYASKLLSAYTTEALIRERLQEMLENGDEEIESGMGDPLKKFTVDLTKE
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHH
AKKGKLTPVIGREKEINRMIEILSRKSKNNPVLVGDAGVGKTAVVEGLAQLIVDENPPSY
HCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCHHH
LKNKKILQLDMAALLAGSKFRGEFEERLKSVIDTVKEKSDEIILFIDELHNIIGAGVAEG
HCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCC
NAMDAANILKPALARGEIKVIGATTYEEYKKYIEKDKALARRFQPVYVQEPTPEQAIEIL
CCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHH
KGIKETYEKHHKVEILNEALIAAVNLSHRYINDRFLPDKAIDLIDEACARVKLRNSAKPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHH
KIRELEKKLSKLEEEINKLTLEEKYEEASKKKAEYFDLQKELEQAQKAAKRVQSEISNVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DEDIIASLVQEWTGIPVTRMVEDEKKKLANLENEIHKRLVDQDEAVNTVADHIKKARAGL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
KDPKKPVGSFLFLGPTGVGKTELAKTLAEILFGTEDALVRIDMSEYMEKFNVSRLVGAAP
CCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCHHEEEECHHHHHHHHHHHHHHHCCC
GYVGFEQGGQLTEMIRRRPYSVVLFDEVEKAHPDVFNILLQILDDGRLTDSQGRTVNFSN
CCCCCCCCCHHHHHHHHCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECC
TIIILTSNLGSELLNKTKKSVGFVGETEEESYENTKNEIMSQVKLAFRPEFINRLDDIIV
EEEEEECCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHEEE
FKPLGISQIKRIVDIMISRLEERLKEKHISIQITEAAKDVIAKEGFDPVYGARPLRRVIE
ECCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHH
RKIESPLATMIIEDTIKEGDTVIVDSKDGENLEIRKSGGELLKKRD
HHHHCHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCHHHHHCCC
>Mature Secondary Structure
MDGGDLMRFNPNDFTEKSLKAFQEAQNVLGYSGGNILKPEHLLLAILNVEDENVGKIFQG
CCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHEEEEEECCCCCCCHHCCC
TNTNSIKSKLEEALSEEMGVYYSMSYGSAQGIYLSTSLANALQIAKSESDRMGFKKIPLL
CCCHHHHHHHHHHHHHHCCEEEEECCCCCCCEEEEHHHHHHHHHHHCCHHCCCHHHHHHH
ALLLGILKEGTSYASKLLSAYTTEALIRERLQEMLENGDEEIESGMGDPLKKFTVDLTKE
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHH
AKKGKLTPVIGREKEINRMIEILSRKSKNNPVLVGDAGVGKTAVVEGLAQLIVDENPPSY
HCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCHHH
LKNKKILQLDMAALLAGSKFRGEFEERLKSVIDTVKEKSDEIILFIDELHNIIGAGVAEG
HCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCC
NAMDAANILKPALARGEIKVIGATTYEEYKKYIEKDKALARRFQPVYVQEPTPEQAIEIL
CCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHH
KGIKETYEKHHKVEILNEALIAAVNLSHRYINDRFLPDKAIDLIDEACARVKLRNSAKPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHH
KIRELEKKLSKLEEEINKLTLEEKYEEASKKKAEYFDLQKELEQAQKAAKRVQSEISNVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DEDIIASLVQEWTGIPVTRMVEDEKKKLANLENEIHKRLVDQDEAVNTVADHIKKARAGL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
KDPKKPVGSFLFLGPTGVGKTELAKTLAEILFGTEDALVRIDMSEYMEKFNVSRLVGAAP
CCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCHHEEEECHHHHHHHHHHHHHHHCCC
GYVGFEQGGQLTEMIRRRPYSVVLFDEVEKAHPDVFNILLQILDDGRLTDSQGRTVNFSN
CCCCCCCCCHHHHHHHHCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECC
TIIILTSNLGSELLNKTKKSVGFVGETEEESYENTKNEIMSQVKLAFRPEFINRLDDIIV
EEEEEECCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHEEE
FKPLGISQIKRIVDIMISRLEERLKEKHISIQITEAAKDVIAKEGFDPVYGARPLRRVIE
ECCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHH
RKIESPLATMIIEDTIKEGDTVIVDSKDGENLEIRKSGGELLKKRD
HHHHCHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]