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The map label for this gene is ykuC [H]

Identifier: 160902975

GI number: 160902975

Start: 1656816

End: 1658087

Strand: Direct

Name: ykuC [H]

Synonym: Pmob_1532

Alternate gene names: 160902975

Gene position: 1656816-1658087 (Clockwise)

Preceding gene: 160902974

Following gene: 160902981

Centisome position: 76.37

GC content: 34.2

Gene sequence:

>1272_bases
ATGACAAATGAGCAAAAAAGAAACTTTTTGCTATATTCTGCAGGTAGGCTTGTATCTTTAATAGGAACTGGCGTACAAAT
GATTGCTTTACCTCTTTATATTCTTGATCTTACAGGCTCTGGAACCCTTATGGGTACATTTGCTCTTTTAAGCATGCTTC
CAGGATTAATTTTTTCACCGATAGCAGGGGTTTTGGGAGATCGAAGAAATCGAAAGAAAATTATGGTGAATATGGACTAT
TTACGTGGGATAATTATACTTTTTATGGCATATTCAGCCTATCAAGGTTGGATGAACATCGCCTTTATCTTCACTGCTCA
AGTATTTATTTCTATATTAGACAGTGTTTTCGGCGGCTCAACCAATGCGATGCTTCCAGACTTAGTCCCTATTGAATTCC
TCACAAAAGCTAATTCATTAAATTCTTCAATAAATGGTATTTCTAATATTATAGGACCAATTCTTGGAGGAATCATATAT
GGATTTGGCGGAATAAAAGTTGTGTTTCTTATAAATGGAATTTCCTTCGTTATTTCTGCTATAAGCGAAATGTTTATTAC
TTACGTACCACATTTTGAAGGTAAGCAGAAAATATCCTTTAAATCCATGTTTTCAGACATCAAAGAAGGCTTAGTTTTTA
TAAGAGGAAGAAAGGGTTTGAAAGAACTGCTTTTATTTGCATTGGTTGTCAATTTTTTAATGGCTCCTATTCTTACGATT
GTGCTCCCTTATGTATTAAGGCAAGAAATTGGGTTTACGAGCGAACAGTATGGAATCACACAATCATCTTTTACCGTGGG
AATACTAATTGGCAGTATTTTAATTGGTACTATTTTTTCTAAAAGTAATCCAAAAAAATCTATGACACTCGGTTTAACAG
TAGAGGCTGTCATGTTTTTCATCATTTCAGGTTTATTTTTTCCTAATATCGTTACCAAATTCGGAGGTGCCTCATGGACC
TTCTTAATAATTTTGTACATAAACCTTATGATAATAGGTGTGAGCAATGCTTTTATAAATATACCTATTGATACCAACAT
GCAAAAAATGACACCAACCAACGTAAGATCTCGTGTTTTTACAGTTTTGGGGTTGATTGCTCAAGGAGCTGTACCTGTTG
GTATGCAGATATATGGTATTCTTTTAGATTTAATGAAGGGATATCAAATTGCACTGTTTGCGAGCATAGTATCAGTTATT
GTAATTATCCTCTTTTTAAAAATTGCACCAGAAGAAACGTTCAATCCTAAACCTGTTAGTGAAGAAGCGTGA

Upstream 100 bases:

>100_bases
TGTGACAGAACAGTCTAACGGCATACTTTTATGGATATTGTTAGGAGTAGGGATATTTTTACGTTTCACATCTATACATA
TTATACGAGGGGGAAATTCA

Downstream 100 bases:

>100_bases
AAGTCGAACCTAGATAAAATCAATTTATTATTTAGTGTTTTTTGAATATATATGTTTTTCCACAATCTTTATTTCTTCTT
CTGTTAAACCATATAACGAA

Product: major facilitator transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MTNEQKRNFLLYSAGRLVSLIGTGVQMIALPLYILDLTGSGTLMGTFALLSMLPGLIFSPIAGVLGDRRNRKKIMVNMDY
LRGIIILFMAYSAYQGWMNIAFIFTAQVFISILDSVFGGSTNAMLPDLVPIEFLTKANSLNSSINGISNIIGPILGGIIY
GFGGIKVVFLINGISFVISAISEMFITYVPHFEGKQKISFKSMFSDIKEGLVFIRGRKGLKELLLFALVVNFLMAPILTI
VLPYVLRQEIGFTSEQYGITQSSFTVGILIGSILIGTIFSKSNPKKSMTLGLTVEAVMFFIISGLFFPNIVTKFGGASWT
FLIILYINLMIIGVSNAFINIPIDTNMQKMTPTNVRSRVFTVLGLIAQGAVPVGMQIYGILLDLMKGYQIALFASIVSVI
VIILFLKIAPEETFNPKPVSEEA

Sequences:

>Translated_423_residues
MTNEQKRNFLLYSAGRLVSLIGTGVQMIALPLYILDLTGSGTLMGTFALLSMLPGLIFSPIAGVLGDRRNRKKIMVNMDY
LRGIIILFMAYSAYQGWMNIAFIFTAQVFISILDSVFGGSTNAMLPDLVPIEFLTKANSLNSSINGISNIIGPILGGIIY
GFGGIKVVFLINGISFVISAISEMFITYVPHFEGKQKISFKSMFSDIKEGLVFIRGRKGLKELLLFALVVNFLMAPILTI
VLPYVLRQEIGFTSEQYGITQSSFTVGILIGSILIGTIFSKSNPKKSMTLGLTVEAVMFFIISGLFFPNIVTKFGGASWT
FLIILYINLMIIGVSNAFINIPIDTNMQKMTPTNVRSRVFTVLGLIAQGAVPVGMQIYGILLDLMKGYQIALFASIVSVI
VIILFLKIAPEETFNPKPVSEEA
>Mature_422_residues
TNEQKRNFLLYSAGRLVSLIGTGVQMIALPLYILDLTGSGTLMGTFALLSMLPGLIFSPIAGVLGDRRNRKKIMVNMDYL
RGIIILFMAYSAYQGWMNIAFIFTAQVFISILDSVFGGSTNAMLPDLVPIEFLTKANSLNSSINGISNIIGPILGGIIYG
FGGIKVVFLINGISFVISAISEMFITYVPHFEGKQKISFKSMFSDIKEGLVFIRGRKGLKELLLFALVVNFLMAPILTIV
LPYVLRQEIGFTSEQYGITQSSFTVGILIGSILIGTIFSKSNPKKSMTLGLTVEAVMFFIISGLFFPNIVTKFGGASWTF
LIILYINLMIIGVSNAFINIPIDTNMQKMTPTNVRSRVFTVLGLIAQGAVPVGMQIYGILLDLMKGYQIALFASIVSVIV
IILFLKIAPEETFNPKPVSEEA

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004751
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46299; Mature: 46168

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNEQKRNFLLYSAGRLVSLIGTGVQMIALPLYILDLTGSGTLMGTFALLSMLPGLIFSP
CCCCCCCCEEEEEHHHHHHHHHCCHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHH
IAGVLGDRRNRKKIMVNMDYLRGIIILFMAYSAYQGWMNIAFIFTAQVFISILDSVFGGS
HHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TNAMLPDLVPIEFLTKANSLNSSINGISNIIGPILGGIIYGFGGIKVVFLINGISFVISA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHHHH
ISEMFITYVPHFEGKQKISFKSMFSDIKEGLVFIRGRKGLKELLLFALVVNFLMAPILTI
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHH
VLPYVLRQEIGFTSEQYGITQSSFTVGILIGSILIGTIFSKSNPKKSMTLGLTVEAVMFF
HHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHH
IISGLFFPNIVTKFGGASWTFLIILYINLMIIGVSNAFINIPIDTNMQKMTPTNVRSRVF
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEECCCEEEECCCCCCCCCCCHHHHHHHH
TVLGLIAQGAVPVGMQIYGILLDLMKGYQIALFASIVSVIVIILFLKIAPEETFNPKPVS
HHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
EEA
CCC
>Mature Secondary Structure 
TNEQKRNFLLYSAGRLVSLIGTGVQMIALPLYILDLTGSGTLMGTFALLSMLPGLIFSP
CCCCCCCEEEEEHHHHHHHHHCCHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHH
IAGVLGDRRNRKKIMVNMDYLRGIIILFMAYSAYQGWMNIAFIFTAQVFISILDSVFGGS
HHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TNAMLPDLVPIEFLTKANSLNSSINGISNIIGPILGGIIYGFGGIKVVFLINGISFVISA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHHHH
ISEMFITYVPHFEGKQKISFKSMFSDIKEGLVFIRGRKGLKELLLFALVVNFLMAPILTI
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHH
VLPYVLRQEIGFTSEQYGITQSSFTVGILIGSILIGTIFSKSNPKKSMTLGLTVEAVMFF
HHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHH
IISGLFFPNIVTKFGGASWTFLIILYINLMIIGVSNAFINIPIDTNMQKMTPTNVRSRVF
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEECCCEEEECCCCCCCCCCCHHHHHHHH
TVLGLIAQGAVPVGMQIYGILLDLMKGYQIALFASIVSVIVIILFLKIAPEETFNPKPVS
HHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
EEA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]