Click here to switch to the map view.

The map label for this gene is flhF [H]

Identifier: 160902845

GI number: 160902845

Start: 1505431

End: 1506747

Strand: Direct

Name: flhF [H]

Synonym: Pmob_1399

Alternate gene names: 160902845

Gene position: 1505431-1506747 (Clockwise)

Preceding gene: 160902844

Following gene: 160902846

Centisome position: 69.39

GC content: 31.44

Gene sequence:

>1317_bases
ATGCAAATTAAAAAACTTACAGTAAAAACAATTTCTGAAGCGATGGAAAAGATAAGAAGAGAATTTGGAGAAGACGCATA
TATTTTAGACACAAAAAAAGTAAAAAAGGGGGGCTTCTTTGGAATCGGTGGAGAAAAATACCTTGAAGTAACTGTTTTGA
GTGAGGAAAATAAAAATTCTCAATACAAGCCTCAAAAAACAAAAAAATACCCGCAAGAATCTGAAAATACCTATACGCTA
AACGATCTAATAAAAAGGAATACACCCGAATTTTATAGAAAAAAAGAAAGAGAAGAAAAAATATCAACACCTTCGTATTT
AAAAAGTGATAAAGAACCTAATTATAAGGATTCGAACGACGATTTAACAGAGTTTATAAAAACGAGTAGAGAAATATCCT
CTAAGATAGACAAAAGTGTAGAATCATTTTATCATCAACACATCCAAAAGGAACCTACTGAAAGTGACATCAAAGATAGT
TTGAAATTACAAGATCTGATGAATATGGTTGAAAAGTTGAACAAAAAAATGGAAGCGAACGATCTCTATCTTCAAGATAT
AAAGGATAAATTGTACGAAAAATCGTATTCAAGGATTTTTATCGAATCCTTTTTAAACCAATTGAACGATTTAAAAGTTG
AAGAAAATTGGCAAAACCAAGAAATTATAAGAACCAGATTTGAAAAAAAACTTTATCAAAGCTTCGAAATTTTGAATTTT
GGTGATATAAAGAATAAAGTTATGTTTATAGGTCCTACAGGAGTTGGAAAAACGACAACGTTGGCAAAAATAGCCGCTAA
CTTAAAAAAATTGAATAAAAAAATTGCACTAATTACAATCGACACGTACAGAATAGCTGCAACAGATCAGTTAAAAACTT
ATGCAGATATACTAGGTGTTTCGCTTCACATTTGTTATACCCCGTCTGACCTTAAAATTGCTTTGGAATCACTTTTGAAT
TTTGATGTGATTCTAATAGACACAGCTGGAAGAAGCCATAAGAACAATTTACAGATGGGGGAACTAAAAGTGTTCAAAGA
CGTAGTTGAGCCTGATTACAATATAATGCTGGTATCCTCCAACACAAATTGTGAAGATATGATGCATATTTACGATAATT
TTTCTTATCTAAAACCCAACGCATTAATTTTTACAAAGATGGATGAAACGTCATCATATGGGCAATTATTTTCTTTTCTG
GAATATTCTAAATTACCTTTGTTGGGGATAACAGATGGTCAAAGAGTTCCTGAAGATTTGAAGTTTCCTTCTAAAGAATG
GCTGACTCATGCAGCAGTGGAGGAGGTATTTAAATGA

Upstream 100 bases:

>100_bases
AAATTTGTTCAAAACATCAGTATTGTAGCATACGAAGAGATACCTTCAGATACCTCTCTCAACGTAAATGAAATAGTGAA
AATAGAAGGTGTGGGATCCA

Downstream 100 bases:

>100_bases
ACCGGATATATCGTGATCAAGCAACTGGTTTAAGAGAAGAGTTTTCTAATACACAAACAAAAATTATAACAATCGTAAGC
GGAAAGGGAGGAGTCGGCAA

Product: GTP-binding signal recognition particle

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MQIKKLTVKTISEAMEKIRREFGEDAYILDTKKVKKGGFFGIGGEKYLEVTVLSEENKNSQYKPQKTKKYPQESENTYTL
NDLIKRNTPEFYRKKEREEKISTPSYLKSDKEPNYKDSNDDLTEFIKTSREISSKIDKSVESFYHQHIQKEPTESDIKDS
LKLQDLMNMVEKLNKKMEANDLYLQDIKDKLYEKSYSRIFIESFLNQLNDLKVEENWQNQEIIRTRFEKKLYQSFEILNF
GDIKNKVMFIGPTGVGKTTTLAKIAANLKKLNKKIALITIDTYRIAATDQLKTYADILGVSLHICYTPSDLKIALESLLN
FDVILIDTAGRSHKNNLQMGELKVFKDVVEPDYNIMLVSSNTNCEDMMHIYDNFSYLKPNALIFTKMDETSSYGQLFSFL
EYSKLPLLGITDGQRVPEDLKFPSKEWLTHAAVEEVFK

Sequences:

>Translated_438_residues
MQIKKLTVKTISEAMEKIRREFGEDAYILDTKKVKKGGFFGIGGEKYLEVTVLSEENKNSQYKPQKTKKYPQESENTYTL
NDLIKRNTPEFYRKKEREEKISTPSYLKSDKEPNYKDSNDDLTEFIKTSREISSKIDKSVESFYHQHIQKEPTESDIKDS
LKLQDLMNMVEKLNKKMEANDLYLQDIKDKLYEKSYSRIFIESFLNQLNDLKVEENWQNQEIIRTRFEKKLYQSFEILNF
GDIKNKVMFIGPTGVGKTTTLAKIAANLKKLNKKIALITIDTYRIAATDQLKTYADILGVSLHICYTPSDLKIALESLLN
FDVILIDTAGRSHKNNLQMGELKVFKDVVEPDYNIMLVSSNTNCEDMMHIYDNFSYLKPNALIFTKMDETSSYGQLFSFL
EYSKLPLLGITDGQRVPEDLKFPSKEWLTHAAVEEVFK
>Mature_438_residues
MQIKKLTVKTISEAMEKIRREFGEDAYILDTKKVKKGGFFGIGGEKYLEVTVLSEENKNSQYKPQKTKKYPQESENTYTL
NDLIKRNTPEFYRKKEREEKISTPSYLKSDKEPNYKDSNDDLTEFIKTSREISSKIDKSVESFYHQHIQKEPTESDIKDS
LKLQDLMNMVEKLNKKMEANDLYLQDIKDKLYEKSYSRIFIESFLNQLNDLKVEENWQNQEIIRTRFEKKLYQSFEILNF
GDIKNKVMFIGPTGVGKTTTLAKIAANLKKLNKKIALITIDTYRIAATDQLKTYADILGVSLHICYTPSDLKIALESLLN
FDVILIDTAGRSHKNNLQMGELKVFKDVVEPDYNIMLVSSNTNCEDMMHIYDNFSYLKPNALIFTKMDETSSYGQLFSFL
EYSKLPLLGITDGQRVPEDLKFPSKEWLTHAAVEEVFK

Specific function: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum [H]

COG id: COG1419

COG function: function code N; Flagellar GTP-binding protein

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI226371618, Length=194, Percent_Identity=28.3505154639175, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI4507215, Length=194, Percent_Identity=28.3505154639175, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1789874, Length=189, Percent_Identity=30.1587301587302, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788963, Length=248, Percent_Identity=27.0161290322581, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17539958, Length=182, Percent_Identity=30.2197802197802, Blast_Score=76, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6325345, Length=193, Percent_Identity=29.5336787564767, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17647949, Length=194, Percent_Identity=28.3505154639175, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000897
- InterPro:   IPR020006 [H]

Pfam domain/function: PF00448 SRP54 [H]

EC number: NA

Molecular weight: Translated: 50930; Mature: 50930

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIKKLTVKTISEAMEKIRREFGEDAYILDTKKVKKGGFFGIGGEKYLEVTVLSEENKNS
CCCHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHCCCCEEECCCCCEEEEEEEECCCCCC
QYKPQKTKKYPQESENTYTLNDLIKRNTPEFYRKKEREEKISTPSYLKSDKEPNYKDSND
CCCCHHHHCCCCCCCCCEEHHHHHHCCCHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCH
DLTEFIKTSREISSKIDKSVESFYHQHIQKEPTESDIKDSLKLQDLMNMVEKLNKKMEAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
DLYLQDIKDKLYEKSYSRIFIESFLNQLNDLKVEENWQNQEIIRTRFEKKLYQSFEILNF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
GDIKNKVMFIGPTGVGKTTTLAKIAANLKKLNKKIALITIDTYRIAATDQLKTYADILGV
CCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEEEEEEEEEEEHHHHHHHHHHHCC
SLHICYTPSDLKIALESLLNFDVILIDTAGRSHKNNLQMGELKVFKDVVEPDYNIMLVSS
EEEEEECCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEC
NTNCEDMMHIYDNFSYLKPNALIFTKMDETSSYGQLFSFLEYSKLPLLGITDGQRVPEDL
CCCHHHHHHHHHCCCEECCCEEEEEECCCCCHHHHHHHHHHHCCCCEEECCCCCCCCHHC
KFPSKEWLTHAAVEEVFK
CCCCHHHHHHHHHHHHHC
>Mature Secondary Structure
MQIKKLTVKTISEAMEKIRREFGEDAYILDTKKVKKGGFFGIGGEKYLEVTVLSEENKNS
CCCHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHCCCCEEECCCCCEEEEEEEECCCCCC
QYKPQKTKKYPQESENTYTLNDLIKRNTPEFYRKKEREEKISTPSYLKSDKEPNYKDSND
CCCCHHHHCCCCCCCCCEEHHHHHHCCCHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCH
DLTEFIKTSREISSKIDKSVESFYHQHIQKEPTESDIKDSLKLQDLMNMVEKLNKKMEAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
DLYLQDIKDKLYEKSYSRIFIESFLNQLNDLKVEENWQNQEIIRTRFEKKLYQSFEILNF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
GDIKNKVMFIGPTGVGKTTTLAKIAANLKKLNKKIALITIDTYRIAATDQLKTYADILGV
CCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEEEEEEEEEEEHHHHHHHHHHHCC
SLHICYTPSDLKIALESLLNFDVILIDTAGRSHKNNLQMGELKVFKDVVEPDYNIMLVSS
EEEEEECCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEC
NTNCEDMMHIYDNFSYLKPNALIFTKMDETSSYGQLFSFLEYSKLPLLGITDGQRVPEDL
CCCHHHHHHHHHCCCEECCCEEEEEECCCCCHHHHHHHHHHHCCCCEEECCCCCCCCHHC
KFPSKEWLTHAAVEEVFK
CCCCHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1447978; 9384377 [H]