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The map label for this gene is yqjC [H]

Identifier: 160902028

GI number: 160902028

Start: 606877

End: 607281

Strand: Direct

Name: yqjC [H]

Synonym: Pmob_0552

Alternate gene names: 160902028

Gene position: 606877-607281 (Clockwise)

Preceding gene: 160902027

Following gene: 160902029

Centisome position: 27.97

GC content: 35.06

Gene sequence:

>405_bases
ATGGAGCCAAAAATTGACCACATCGGAATTGCTGTCAATTCCATAGAAGAAGCATTCAAGTTGTATAGGGACCTACTTCA
CATTGAAAAGAGCACTGAAGAGATCCTTGAAGATAGGGGTATAAAAGTTACCTTTTTGTACATAAAAGATGTTAGAATAG
AACTTATGGAGCCTATGAGAGAAGACTCTGAAATATCAAATTTTTTAAAAAAACGAGGCGAGGGATTCCACCACATCGCA
TTTCAAGTAGATAACATTAAAATGGTCTTAGAAAACGCAAAAAAAATGGGTTACAAAACCTTATCTGATGAGCCTAATCG
AGGAGCAGGTGGAAGTTTAGTTTTCTTTTTACATCCAAAATCTGCTAACGGTATTTTAACCGAGTTTGTTGAATATCAAA
AATAG

Upstream 100 bases:

>100_bases
CTGATAGAAAATTACTTGGAAGGTTATTCTTTAGAAAATCAAGATGCCGATTCCCTTAAAAAAGACGTTATAGCATTCAT
CTGTGAAGAGGAGGGAAACG

Downstream 100 bases:

>100_bases
CAATTTATGGAACGAAGGGGCGCTGACACGACGTTTTAGAGTTTTCAATTATAGTATAAATATCGCAAATGAGGAGGTCT
TATATATGCCAGATGAAGAA

Product: methylmalonyl-CoA epimerase

Products: glutathione; methylglyoxal

Alternate protein names: NA

Number of amino acids: Translated: 134; Mature: 134

Protein sequence:

>134_residues
MEPKIDHIGIAVNSIEEAFKLYRDLLHIEKSTEEILEDRGIKVTFLYIKDVRIELMEPMREDSEISNFLKKRGEGFHHIA
FQVDNIKMVLENAKKMGYKTLSDEPNRGAGGSLVFFLHPKSANGILTEFVEYQK

Sequences:

>Translated_134_residues
MEPKIDHIGIAVNSIEEAFKLYRDLLHIEKSTEEILEDRGIKVTFLYIKDVRIELMEPMREDSEISNFLKKRGEGFHHIA
FQVDNIKMVLENAKKMGYKTLSDEPNRGAGGSLVFFLHPKSANGILTEFVEYQK
>Mature_134_residues
MEPKIDHIGIAVNSIEEAFKLYRDLLHIEKSTEEILEDRGIKVTFLYIKDVRIELMEPMREDSEISNFLKKRGEGFHHIA
FQVDNIKMVLENAKKMGYKTLSDEPNRGAGGSLVFFLHPKSANGILTEFVEYQK

Specific function: Unknown

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyoxalase I family [H]

Homologues:

Organism=Homo sapiens, GI188035928, Length=127, Percent_Identity=37.007874015748, Blast_Score=97, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17506387, Length=128, Percent_Identity=33.59375, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360
- InterPro:   IPR018146
- InterPro:   IPR017515 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 4.4.1.5

Molecular weight: Translated: 15471; Mature: 15471

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPKIDHIGIAVNSIEEAFKLYRDLLHIEKSTEEILEDRGIKVTFLYIKDVRIELMEPMR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEHHHHHHHHHCC
EDSEISNFLKKRGEGFHHIAFQVDNIKMVLENAKKMGYKTLSDEPNRGAGGSLVFFLHPK
CCHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCC
SANGILTEFVEYQK
CCCCHHHHHHHHCC
>Mature Secondary Structure
MEPKIDHIGIAVNSIEEAFKLYRDLLHIEKSTEEILEDRGIKVTFLYIKDVRIELMEPMR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEHHHHHHHHHCC
EDSEISNFLKKRGEGFHHIAFQVDNIKMVLENAKKMGYKTLSDEPNRGAGGSLVFFLHPK
CCHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCC
SANGILTEFVEYQK
CCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]