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The map label for this gene is cisA [H]

Identifier: 160901910

GI number: 160901910

Start: 462395

End: 463963

Strand: Direct

Name: cisA [H]

Synonym: Pmob_0428

Alternate gene names: 160901910

Gene position: 462395-463963 (Clockwise)

Preceding gene: 160901909

Following gene: 160901911

Centisome position: 21.31

GC content: 38.43

Gene sequence:

>1569_bases
GTGAGAAAGGTAACAAGGATTGATGGAAACAATGCTCTCCAAGCTTTCAAGCCAAAGGTGAGGGTAGCGGCTTATTGCAG
GGTTTCAACAGACAGTGATGAACAAATGGCAAGCCTGGAAGCACAAAAAGACCATTATGAATCCTATATAAGAGCAAATC
CTGATTGGGAGTTTGCAGGGATCTACTATGATGAAGGCATATCAGGCACAAAAAAGGAAAACCGAACTGGACTTTTGAGA
CTGCTTGCAGATTGTGAAAACAAGAAAATTGACTTTATTATAACCAAGTCAGTCAGCAGATTTGCCAGAAACACAACCGA
CTGCATTGAAATGGTGAGAAAACTTACCGATCTCGGTGTTTTCATCTATTTCGAGAAAGAGAATATAAACACACAGCGCA
TGGAAGGCGAATTGGTGCTGACAATTTTGGGCAGTCTTGCAGAAAACGAGTCATTATCCATTGCAGAAAATAGTAAGTGG
TCTATCAGACGTAGGTTCCAAAACGGATCATACAAAATTTCGTATCCTCCCTATGGTTACGATTATGTGGATGGAAAGCT
ATTTATCAATAAAGAACAGGCTGAAATCATAAAGCGGATTTTTTCCGAGGCTTTGGCTGGTAAAGGCACACAGAAAATTG
CAGATGGGTTAAATTTGGATAAAATCCCAACAAAGAGAGGTTCACACTGGACAGCGACCACTATCCGCGGTATCCTTAGC
AATGAAAAATATACCGGGGATGTCCTTCTGCAAAAAACATATACAGATGAGAATTTTAAGCGGCATTATAATCGTGGTGA
AAAGGATCAATACATGATAAAGGATCATCATGAAGCCATTATATCCCATGAGGAATTTGAAGCCGCCCAAGAGATATTAA
AGCAAAGAGGAAAAGAAAAAGGTGTAATTAAGGGAAGCAGCAAATATCAAAACCGCTACCTGTTCTCAGGGAAAATCAAA
TGCGCAGAATGTGGCAGCAATTTTAAACGTCGAATTCATGGCAGCGGTAACCGTAAATATATTGCCTGGTGCTGCACAAA
GCATATAAAGGACGCATCAAGCTGTTCCATGAAGTTTGTCAGAGAGGATGCAATTCATCAGGCCTTTGCTGTAATGATCA
ATAAGCTTATTTTCGGTCATAAATTCATTATAAGACCATTGCTACAAAGCTTAAAGAAAGCAAATTACTCAGATAATATA
GCGAAGATTCAAGAACTGGAAACAAAAATCAAAGAAAATACAGAGCGGGTTCAGGTAATTATGGGACTTATAGCTAAGGG
ATACCTGGAACCCGCTCTTTTTAATACACAGAAAAATGAGCTGCTTAAAGAAGCGGCTTTATTAAAAGAACAAAAAGAAA
CCTTAAAACGCGAAATTGATGGAGGCATAACTACTCTTGTTGAGGCAGAAAAGATTCTTAAATTTGCAACGAAAGCTGAA
AAGCAGATTAATGCATTTGAAAGTGAAATATTTGAGAATTTTATTGAAGAAATCATTGTGTTTTCTCAGGAGGAAATTGG
TTTCAAAATGAAATGCGGGTTGAACTTAAGGGATAGGCTGGTGAAATAA

Upstream 100 bases:

>100_bases
AAAACTTTCTCGCCGATGTATGCACAGCTTATGGCCTAATTGGCTTGCTATTAGCGGCACACAGAGGTAACATGTCACAT
ACCCAAAGGAGGTGAAAACA

Downstream 100 bases:

>100_bases
TGAGCCATATACCTTTTGGATATACCATTCAAAACGGCAGGGCTGTAGTTAATGAAGAGGAAGCAGTTAAAATTAAGAAG
CTATTTAGGTTTATCTTTCA

Product: resolvase domain-containing protein

Products: NA

Alternate protein names: Stage IV sporulation protein CA [H]

Number of amino acids: Translated: 522; Mature: 522

Protein sequence:

>522_residues
MRKVTRIDGNNALQAFKPKVRVAAYCRVSTDSDEQMASLEAQKDHYESYIRANPDWEFAGIYYDEGISGTKKENRTGLLR
LLADCENKKIDFIITKSVSRFARNTTDCIEMVRKLTDLGVFIYFEKENINTQRMEGELVLTILGSLAENESLSIAENSKW
SIRRRFQNGSYKISYPPYGYDYVDGKLFINKEQAEIIKRIFSEALAGKGTQKIADGLNLDKIPTKRGSHWTATTIRGILS
NEKYTGDVLLQKTYTDENFKRHYNRGEKDQYMIKDHHEAIISHEEFEAAQEILKQRGKEKGVIKGSSKYQNRYLFSGKIK
CAECGSNFKRRIHGSGNRKYIAWCCTKHIKDASSCSMKFVREDAIHQAFAVMINKLIFGHKFIIRPLLQSLKKANYSDNI
AKIQELETKIKENTERVQVIMGLIAKGYLEPALFNTQKNELLKEAALLKEQKETLKREIDGGITTLVEAEKILKFATKAE
KQINAFESEIFENFIEEIIVFSQEEIGFKMKCGLNLRDRLVK

Sequences:

>Translated_522_residues
MRKVTRIDGNNALQAFKPKVRVAAYCRVSTDSDEQMASLEAQKDHYESYIRANPDWEFAGIYYDEGISGTKKENRTGLLR
LLADCENKKIDFIITKSVSRFARNTTDCIEMVRKLTDLGVFIYFEKENINTQRMEGELVLTILGSLAENESLSIAENSKW
SIRRRFQNGSYKISYPPYGYDYVDGKLFINKEQAEIIKRIFSEALAGKGTQKIADGLNLDKIPTKRGSHWTATTIRGILS
NEKYTGDVLLQKTYTDENFKRHYNRGEKDQYMIKDHHEAIISHEEFEAAQEILKQRGKEKGVIKGSSKYQNRYLFSGKIK
CAECGSNFKRRIHGSGNRKYIAWCCTKHIKDASSCSMKFVREDAIHQAFAVMINKLIFGHKFIIRPLLQSLKKANYSDNI
AKIQELETKIKENTERVQVIMGLIAKGYLEPALFNTQKNELLKEAALLKEQKETLKREIDGGITTLVEAEKILKFATKAE
KQINAFESEIFENFIEEIIVFSQEEIGFKMKCGLNLRDRLVK
>Mature_522_residues
MRKVTRIDGNNALQAFKPKVRVAAYCRVSTDSDEQMASLEAQKDHYESYIRANPDWEFAGIYYDEGISGTKKENRTGLLR
LLADCENKKIDFIITKSVSRFARNTTDCIEMVRKLTDLGVFIYFEKENINTQRMEGELVLTILGSLAENESLSIAENSKW
SIRRRFQNGSYKISYPPYGYDYVDGKLFINKEQAEIIKRIFSEALAGKGTQKIADGLNLDKIPTKRGSHWTATTIRGILS
NEKYTGDVLLQKTYTDENFKRHYNRGEKDQYMIKDHHEAIISHEEFEAAQEILKQRGKEKGVIKGSSKYQNRYLFSGKIK
CAECGSNFKRRIHGSGNRKYIAWCCTKHIKDASSCSMKFVREDAIHQAFAVMINKLIFGHKFIIRPLLQSLKKANYSDNI
AKIQELETKIKENTERVQVIMGLIAKGYLEPALFNTQKNELLKEAALLKEQKETLKREIDGGITTLVEAEKILKFATKAE
KQINAFESEIFENFIEEIIVFSQEEIGFKMKCGLNLRDRLVK

Specific function: Putative site-specific recombinase having a very important role in sporulation. It probably plays a role in the recombination of spoIIIC and spoIVCB to form sigma K factor [H]

COG id: COG1961

COG function: function code L; Site-specific recombinases, DNA invertase Pin homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 recombinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011109
- InterPro:   IPR006118
- InterPro:   IPR006119 [H]

Pfam domain/function: PF07508 Recombinase; PF00239 Resolvase [H]

EC number: NA

Molecular weight: Translated: 60037; Mature: 60037

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKVTRIDGNNALQAFKPKVRVAAYCRVSTDSDEQMASLEAQKDHYESYIRANPDWEFAG
CCCEEEECCCCCHHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEE
IYYDEGISGTKKENRTGLLRLLADCENKKIDFIITKSVSRFARNTTDCIEMVRKLTDLGV
EEECCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEHHHHHHHCCCHHHHHHHHHHHHCEE
FIYFEKENINTQRMEGELVLTILGSLAENESLSIAENSKWSIRRRFQNGSYKISYPPYGY
EEEEECCCCCCHHHCCHHHHHHHHHHCCCCCCEEECCCCHHHHHHHCCCCEEEECCCCCC
DYVDGKLFINKEQAEIIKRIFSEALAGKGTQKIADGLNLDKIPTKRGSHWTATTIRGILS
CCCCCEEEECCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHC
NEKYTGDVLLQKTYTDENFKRHYNRGEKDQYMIKDHHEAIISHEEFEAAQEILKQRGKEK
CCCCCCCEEEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GVIKGSSKYQNRYLFSGKIKCAECGSNFKRRIHGSGNRKYIAWCCTKHIKDASSCSMKFV
CCCCCCCHHCCEEEEECCEEHHHHCCHHHHHHCCCCCCEEEEEEHHHHHCCHHHHHHHHH
REDAIHQAFAVMINKLIFGHKFIIRPLLQSLKKANYSDNIAKIQELETKIKENTERVQVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
MGLIAKGYLEPALFNTQKNELLKEAALLKEQKETLKREIDGGITTLVEAEKILKFATKAE
HHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
KQINAFESEIFENFIEEIIVFSQEEIGFKMKCGLNLRDRLVK
HHHHHHHHHHHHHHHHHHHHHCHHHCCEEEECCCCHHHHCCC
>Mature Secondary Structure
MRKVTRIDGNNALQAFKPKVRVAAYCRVSTDSDEQMASLEAQKDHYESYIRANPDWEFAG
CCCEEEECCCCCHHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEE
IYYDEGISGTKKENRTGLLRLLADCENKKIDFIITKSVSRFARNTTDCIEMVRKLTDLGV
EEECCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEHHHHHHHCCCHHHHHHHHHHHHCEE
FIYFEKENINTQRMEGELVLTILGSLAENESLSIAENSKWSIRRRFQNGSYKISYPPYGY
EEEEECCCCCCHHHCCHHHHHHHHHHCCCCCCEEECCCCHHHHHHHCCCCEEEECCCCCC
DYVDGKLFINKEQAEIIKRIFSEALAGKGTQKIADGLNLDKIPTKRGSHWTATTIRGILS
CCCCCEEEECCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHC
NEKYTGDVLLQKTYTDENFKRHYNRGEKDQYMIKDHHEAIISHEEFEAAQEILKQRGKEK
CCCCCCCEEEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GVIKGSSKYQNRYLFSGKIKCAECGSNFKRRIHGSGNRKYIAWCCTKHIKDASSCSMKFV
CCCCCCCHHCCEEEEECCEEHHHHCCHHHHHHCCCCCCEEEEEEHHHHHCCHHHHHHHHH
REDAIHQAFAVMINKLIFGHKFIIRPLLQSLKKANYSDNIAKIQELETKIKENTERVQVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
MGLIAKGYLEPALFNTQKNELLKEAALLKEQKETLKREIDGGITTLVEAEKILKFATKAE
HHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
KQINAFESEIFENFIEEIIVFSQEEIGFKMKCGLNLRDRLVK
HHHHHHHHHHHHHHHHHHHHHCHHHCCEEEECCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2105293; 7704261; 8969508; 9384377 [H]