Click here to switch to the map view.

The map label for this gene is efp

Identifier: 160901502

GI number: 160901502

Start: 8317

End: 8874

Strand: Direct

Name: efp

Synonym: Pmob_0011

Alternate gene names: 160901502

Gene position: 8317-8874 (Clockwise)

Preceding gene: 160901500

Following gene: 160901506

Centisome position: 0.38

GC content: 36.56

Gene sequence:

>558_bases
ATGATCGATGTAGGAGACTTAAGAAAAGGAGATATGATAGTTTATCAAAACGAAATGTACCGTGTAATTGAAGCCAATAA
GCATTTTATGGGAAGAGGCAGCGGACTGATTAGAACCCGCCTAAAAAGTGTCATAACGGGATTAATAAAAGAGGTTAGTT
TTTCTAGTGGTGAGAAGGTTGAAGAAGCTGATATAAGTTTTAGGAAAGCCCAGTATTTATACAACGATGGCGATCATTAT
TACTTTATGCTACTCGACACCTATGAACAATATTCTTTGCCTGCTCAAGAGTTAGAAGATGAAAAATTTTATTTAACCGA
AAATTTAGAAGTAGATCTAATCTTTTTTAATGGAAATCCTGTTTCTATTCAACTTCCCACAGTTGTGGTTCTAACCGTTA
TTGACACAGAACCTAACTTTAAAGGAAACACAGTGTCGGGTGGTGGCAAACCAGCAACATTAGAAACAGGATTGAAAACC
ACTGTCCCTTTTTTTGTGGAAAGAGGCCAAAAAATAAAAGTAGACACTCGCACTGGAGATTACCTAGAAAGGGCATAA

Upstream 100 bases:

>100_bases
TTCACCTATTTTTAAACATCATTAAATTCTAATAATGATTTTAGGACGTTAGTTTTTATTGCCAATCGGTGATTAACGAA
AAATGCAAGGAGGAAATTGA

Downstream 100 bases:

>100_bases
AAAGTGCATATATTAAAGGCTCGATATATTTTTATCGAGCCTTTTTATTTTTCTTGGGGTTGGTATTCATGTTTGCCTTC
GGATGTATAAGATTCTTCGA

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MIDVGDLRKGDMIVYQNEMYRVIEANKHFMGRGSGLIRTRLKSVITGLIKEVSFSSGEKVEEADISFRKAQYLYNDGDHY
YFMLLDTYEQYSLPAQELEDEKFYLTENLEVDLIFFNGNPVSIQLPTVVVLTVIDTEPNFKGNTVSGGGKPATLETGLKT
TVPFFVERGQKIKVDTRTGDYLERA

Sequences:

>Translated_185_residues
MIDVGDLRKGDMIVYQNEMYRVIEANKHFMGRGSGLIRTRLKSVITGLIKEVSFSSGEKVEEADISFRKAQYLYNDGDHY
YFMLLDTYEQYSLPAQELEDEKFYLTENLEVDLIFFNGNPVSIQLPTVVVLTVIDTEPNFKGNTVSGGGKPATLETGLKT
TVPFFVERGQKIKVDTRTGDYLERA
>Mature_185_residues
MIDVGDLRKGDMIVYQNEMYRVIEANKHFMGRGSGLIRTRLKSVITGLIKEVSFSSGEKVEEADISFRKAQYLYNDGDHY
YFMLLDTYEQYSLPAQELEDEKFYLTENLEVDLIFFNGNPVSIQLPTVVVLTVIDTEPNFKGNTVSGGGKPATLETGLKT
TVPFFVERGQKIKVDTRTGDYLERA

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=179, Percent_Identity=39.6648044692737, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI87082061, Length=189, Percent_Identity=28.5714285714286, Blast_Score=88, Evalue=4e-19,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_PETMO (A9BEN2)

Other databases:

- EMBL:   CP000879
- RefSeq:   YP_001567083.1
- GeneID:   5757335
- GenomeReviews:   CP000879_GR
- KEGG:   pmo:Pmob_0011
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- ProtClustDB:   PRK00529
- BioCyc:   PMOB403833:PMOB_0011-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 21000; Mature: 21000

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDVGDLRKGDMIVYQNEMYRVIEANKHFMGRGSGLIRTRLKSVITGLIKEVSFSSGEKV
CCCCCCCCCCCEEEEECCEEEEEECCCCEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
EEADISFRKAQYLYNDGDHYYFMLLDTYEQYSLPAQELEDEKFYLTENLEVDLIFFNGNP
CHHCCCEEEEEEEEECCCEEEEEEEECCHHHCCCHHHCCCCEEEEECCCEEEEEEECCCE
VSIQLPTVVVLTVIDTEPNFKGNTVSGGGKPATLETGLKTTVPFFVERGQKIKVDTRTGD
EEEEECEEEEEEEEECCCCCCCCEECCCCCCCEEECCCCCCCHHHHCCCCEEEEECCCCC
YLERA
HHHCC
>Mature Secondary Structure
MIDVGDLRKGDMIVYQNEMYRVIEANKHFMGRGSGLIRTRLKSVITGLIKEVSFSSGEKV
CCCCCCCCCCCEEEEECCEEEEEECCCCEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
EEADISFRKAQYLYNDGDHYYFMLLDTYEQYSLPAQELEDEKFYLTENLEVDLIFFNGNP
CHHCCCEEEEEEEEECCCEEEEEEEECCHHHCCCHHHCCCCEEEEECCCEEEEEEECCCE
VSIQLPTVVVLTVIDTEPNFKGNTVSGGGKPATLETGLKTTVPFFVERGQKIKVDTRTGD
EEEEECEEEEEEEEECCCCCCCCEECCCCCCCEEECCCCCCCHHHHCCCCEEEEECCCCC
YLERA
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA