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The map label for this gene is dnaA [H]

Identifier: 160901492

GI number: 160901492

Start: 53

End: 1417

Strand: Direct

Name: dnaA [H]

Synonym: Pmob_0001

Alternate gene names: 160901492

Gene position: 53-1417 (Clockwise)

Preceding gene: NA

Following gene: 160901497

Centisome position: 0.0

GC content: 32.6

Gene sequence:

>1365_bases
ATGGAAAAGCATGAACTAATAGAAAAACTACGTTCCAACATGTCTAGAGATACCTGGAATAATTGGCTAACAACGGCTCA
AATTTTGGAATTAGACAACAAAAAAGTCGTTGTTGGATTAGGAAATTTATTTATTAAAGAAGCTGTCGAGAAAAGATTCG
GTTCAATAATAAAAGAAACTATAAACAATATCCTAGGCAAACCTGTAGAGGTTGTTTTTAAGGAAATCCCTATTAGCAAA
GAACAAAAAAATGCAGTAAATGGCCCAATAATAAAAAACAGGCCTTTGAAACTATCAGAGTTTAATCCTGAGTTCACCTT
TGACAGCTTTGTTACAGGAAATTCCAATAGAATAGCTTATTATTCAGCCTTGGAAGTTTGTAAAAATCCTGGCAAATATA
ATCCTTTATTTATATATGGAGATGTTGGACTAGGTAAAACTCATCTTTTACATGCAATAGGGAACTTTTTGATGGAAAAT
GCTCCTGATTTGAAGGTTAAGTATGTAACCGCTGAGGATTTTATGAATCAAATGATGGATGGAATAAGAGCTAGTGATAT
GGAGAACTTCCGAGAACGGTTTAGAAGGAATGTTGATTTTTTATTGATAGATGATGTTCAATTTTTAATTGGGAAAAATA
CCGTACAAAGCGAACTTTTTCATACCTTTAATTCTCTTTTTAACTCAAGAAAACAGATAGTAATATGCTCCGATAGAACG
CCCGATGAATTGGCAACCTTTCATCCTAGATTGATTAGTAGGTTTGAAATGGGTTTGATAACTGATATACAAGCACCTGA
TAAGGCAACAAAGTACCTAATAGCTAAGAAAATGGCACAAATGATTTCTCTTCAACTTACCGATGATGTTGCTTATTATT
TGGCTGAACATGTCGATACAAACTTAAGAAAACTTCGGGGCGCAATTATGAACCTTCTGTTGCAAAGTCAAATTTCAGGT
GCACCAGCAAATATCGAATCTGCAAAAACGATAGTGAATTCAATGATGAGAATGAACGCGAACAAAGTTAGGTTCCAATC
ACCAGAAGTTCTTGAAACTGTGAAAATAGATACCGTTATAGATTTGGTTGCTGCTGAATTTGATATAAATAGAAAGGATA
TCTTCTCATCATCTAGAAAAAAAGAAATAGCATTAGCACGTCAAGTTTTAGCTTATCTTTTTAAGACCACTATGAAGTTG
AAAACCAAAGATATCTCCGAAAAATTAGATAAAAATCATTCTACTATTATTCATTCCATCAAAAAAATAGAACATTCTTT
GTTGATGGGAAATGAAATGATAAAAAATAAGATCAACAACATCAAGAACAAATTGGAAGATGAAAAAGGGATTCTTACTT
TATAA

Upstream 100 bases:

>100_bases
TAAATAGCCTTTAATCAGATTTTTAATCAAAAATTTTCTTGATTAAGTTCACCCCTTATGATAAAGTATATATTGGGTTT
TATTCCAAGGGGTGAAAATA

Downstream 100 bases:

>100_bases
AAATAGAAGAAATCGGCCTCAAATTATGATTTAAACAAGAACAAATTGAGGCCGATTTTTTTATTTATAATAATCAGGTT
GTTGCAACAAATGTTTTTTA

Product: chromosomal replication initiator protein DnaA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MEKHELIEKLRSNMSRDTWNNWLTTAQILELDNKKVVVGLGNLFIKEAVEKRFGSIIKETINNILGKPVEVVFKEIPISK
EQKNAVNGPIIKNRPLKLSEFNPEFTFDSFVTGNSNRIAYYSALEVCKNPGKYNPLFIYGDVGLGKTHLLHAIGNFLMEN
APDLKVKYVTAEDFMNQMMDGIRASDMENFRERFRRNVDFLLIDDVQFLIGKNTVQSELFHTFNSLFNSRKQIVICSDRT
PDELATFHPRLISRFEMGLITDIQAPDKATKYLIAKKMAQMISLQLTDDVAYYLAEHVDTNLRKLRGAIMNLLLQSQISG
APANIESAKTIVNSMMRMNANKVRFQSPEVLETVKIDTVIDLVAAEFDINRKDIFSSSRKKEIALARQVLAYLFKTTMKL
KTKDISEKLDKNHSTIIHSIKKIEHSLLMGNEMIKNKINNIKNKLEDEKGILTL

Sequences:

>Translated_454_residues
MEKHELIEKLRSNMSRDTWNNWLTTAQILELDNKKVVVGLGNLFIKEAVEKRFGSIIKETINNILGKPVEVVFKEIPISK
EQKNAVNGPIIKNRPLKLSEFNPEFTFDSFVTGNSNRIAYYSALEVCKNPGKYNPLFIYGDVGLGKTHLLHAIGNFLMEN
APDLKVKYVTAEDFMNQMMDGIRASDMENFRERFRRNVDFLLIDDVQFLIGKNTVQSELFHTFNSLFNSRKQIVICSDRT
PDELATFHPRLISRFEMGLITDIQAPDKATKYLIAKKMAQMISLQLTDDVAYYLAEHVDTNLRKLRGAIMNLLLQSQISG
APANIESAKTIVNSMMRMNANKVRFQSPEVLETVKIDTVIDLVAAEFDINRKDIFSSSRKKEIALARQVLAYLFKTTMKL
KTKDISEKLDKNHSTIIHSIKKIEHSLLMGNEMIKNKINNIKNKLEDEKGILTL
>Mature_454_residues
MEKHELIEKLRSNMSRDTWNNWLTTAQILELDNKKVVVGLGNLFIKEAVEKRFGSIIKETINNILGKPVEVVFKEIPISK
EQKNAVNGPIIKNRPLKLSEFNPEFTFDSFVTGNSNRIAYYSALEVCKNPGKYNPLFIYGDVGLGKTHLLHAIGNFLMEN
APDLKVKYVTAEDFMNQMMDGIRASDMENFRERFRRNVDFLLIDDVQFLIGKNTVQSELFHTFNSLFNSRKQIVICSDRT
PDELATFHPRLISRFEMGLITDIQAPDKATKYLIAKKMAQMISLQLTDDVAYYLAEHVDTNLRKLRGAIMNLLLQSQISG
APANIESAKTIVNSMMRMNANKVRFQSPEVLETVKIDTVIDLVAAEFDINRKDIFSSSRKKEIALARQVLAYLFKTTMKL
KTKDISEKLDKNHSTIIHSIKKIEHSLLMGNEMIKNKINNIKNKLEDEKGILTL

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family [H]

Homologues:

Organism=Escherichia coli, GI2367267, Length=354, Percent_Identity=34.180790960452, Blast_Score=216, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921 [H]

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C [H]

EC number: NA

Molecular weight: Translated: 51939; Mature: 51939

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKHELIEKLRSNMSRDTWNNWLTTAQILELDNKKVVVGLGNLFIKEAVEKRFGSIIKET
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHH
INNILGKPVEVVFKEIPISKEQKNAVNGPIIKNRPLKLSEFNPEFTFDSFVTGNSNRIAY
HHHHHCCHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEH
YSALEVCKNPGKYNPLFIYGDVGLGKTHLLHAIGNFLMENAPDLKVKYVTAEDFMNQMMD
HHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHH
GIRASDMENFRERFRRNVDFLLIDDVQFLIGKNTVQSELFHTFNSLFNSRKQIVICSDRT
HHHHHHHHHHHHHHHCCCCEEEECCHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEECCCC
PDELATFHPRLISRFEMGLITDIQAPDKATKYLIAKKMAQMISLQLTDDVAYYLAEHVDT
CHHHHHHHHHHHHHHHHCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLRKLRGAIMNLLLQSQISGAPANIESAKTIVNSMMRMNANKVRFQSPEVLETVKIDTVI
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHH
DLVAAEFDINRKDIFSSSRKKEIALARQVLAYLFKTTMKLKTKDISEKLDKNHSTIIHSI
HHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
KKIEHSLLMGNEMIKNKINNIKNKLEDEKGILTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEKHELIEKLRSNMSRDTWNNWLTTAQILELDNKKVVVGLGNLFIKEAVEKRFGSIIKET
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHH
INNILGKPVEVVFKEIPISKEQKNAVNGPIIKNRPLKLSEFNPEFTFDSFVTGNSNRIAY
HHHHHCCHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEH
YSALEVCKNPGKYNPLFIYGDVGLGKTHLLHAIGNFLMENAPDLKVKYVTAEDFMNQMMD
HHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHH
GIRASDMENFRERFRRNVDFLLIDDVQFLIGKNTVQSELFHTFNSLFNSRKQIVICSDRT
HHHHHHHHHHHHHHHCCCCEEEECCHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEECCCC
PDELATFHPRLISRFEMGLITDIQAPDKATKYLIAKKMAQMISLQLTDDVAYYLAEHVDT
CHHHHHHHHHHHHHHHHCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLRKLRGAIMNLLLQSQISGAPANIESAKTIVNSMMRMNANKVRFQSPEVLETVKIDTVI
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHH
DLVAAEFDINRKDIFSSSRKKEIALARQVLAYLFKTTMKLKTKDISEKLDKNHSTIIHSI
HHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
KKIEHSLLMGNEMIKNKINNIKNKLEDEKGILTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA