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The map label for this gene is menB [H]

Identifier: 160877601

GI number: 160877601

Start: 5322467

End: 5323372

Strand: Direct

Name: menB [H]

Synonym: Sbal195_4500

Alternate gene names: 160877601

Gene position: 5322467-5323372 (Clockwise)

Preceding gene: 160877600

Following gene: 160877602

Centisome position: 99.54

GC content: 50.0

Gene sequence:

>906_bases
ATGACCCAACAAGTATCAGACATTTTTGATCCCACCCTATGGGATGAAGTCAGTGGATTTCAATTCGACGACATCACCTA
CCACAGAGCTAAAGCCCACGGCACAGTTCGCATTGCCATTAACCGCCCTGAGTGCCGCAACGCCTTCAGACCTAAAACCG
TTGATGAGTTATTTATCGCACTCGATCATGCGCGCCAATGGTCTGATGTAGGTTGTGTACTGCTAACAGGTAATGGTCCT
TCGGCAAAAGATGGTGGCTGGGCGTTCTGTTCGGGTGGCGATCAACGTATTCGCGGCAAAGATGGCTATAAATATGAAGG
CGCCGAAGAAGGTAAAGCCGATCAAGCCAGAATGGGCCGCTTACATATATTAGAAGTGCAACGCTTGATCCGCTTTATGC
CTAAAGTGGTCATCGCCGTTGTGCCGGGTTGGGCGGTAGGTGGCGGCCATAGCTTACACGTAGTATGCGACTTAACCTTA
GCCTCGAAAGAACACGCGATATTTAAGCAGACTGATCCCGACGTAGCGAGCTTCGACTCAGGTTATGGCAGCGCATATCT
TGCCAAGATGATAGGTCAAAAACGTGCCCGCGAAATCTTCTTCTGTGGTTTTAACTACAGCGCCGATGAAGCCTTCGACA
TGGGTATGGTCAATAAATCCGTTCCCCATGCAGAGCTAGAAACCGAGGCATTAATGTGGGCCAAAGAGATTAACTCTAAG
TCGCCTACGGCAATGCGTATGCTTAAATACGGTTTTAACATGACAGATGATGGTATGGTCGGTCAGCAATTATTCGCCGG
TGAAGCGACGCGTTTAGCCTATGCGAGCGCCGAAGCGCAGGAAGGGCGCGATGCCTTCCTCGAGAAACGCGATCAAGATT
TCTCCGCCTTCCCTTGGCATTACTAG

Upstream 100 bases:

>100_bases
GGATTTTGCTATATAGCGCTAAGCTTTAGGCTTAGGTGATTGACCTTATATATGATTCCGCCTAGCCTTTGAGGCATTAC
AGCACAAAGGCCTATGAATC

Downstream 100 bases:

>100_bases
TTTATTAGCAGTGCTTTAATTTACTGCTAGCAGCCCAAAGCCCTCCAGAGTGAGGGCTTTATGTTTTTTACAACGGATAA
ATAGATAAAACCGTTTAAAC

Product: naphthoate synthase

Products: NA

Alternate protein names: DHNA-CoA synthase [H]

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MTQQVSDIFDPTLWDEVSGFQFDDITYHRAKAHGTVRIAINRPECRNAFRPKTVDELFIALDHARQWSDVGCVLLTGNGP
SAKDGGWAFCSGGDQRIRGKDGYKYEGAEEGKADQARMGRLHILEVQRLIRFMPKVVIAVVPGWAVGGGHSLHVVCDLTL
ASKEHAIFKQTDPDVASFDSGYGSAYLAKMIGQKRAREIFFCGFNYSADEAFDMGMVNKSVPHAELETEALMWAKEINSK
SPTAMRMLKYGFNMTDDGMVGQQLFAGEATRLAYASAEAQEGRDAFLEKRDQDFSAFPWHY

Sequences:

>Translated_301_residues
MTQQVSDIFDPTLWDEVSGFQFDDITYHRAKAHGTVRIAINRPECRNAFRPKTVDELFIALDHARQWSDVGCVLLTGNGP
SAKDGGWAFCSGGDQRIRGKDGYKYEGAEEGKADQARMGRLHILEVQRLIRFMPKVVIAVVPGWAVGGGHSLHVVCDLTL
ASKEHAIFKQTDPDVASFDSGYGSAYLAKMIGQKRAREIFFCGFNYSADEAFDMGMVNKSVPHAELETEALMWAKEINSK
SPTAMRMLKYGFNMTDDGMVGQQLFAGEATRLAYASAEAQEGRDAFLEKRDQDFSAFPWHY
>Mature_300_residues
TQQVSDIFDPTLWDEVSGFQFDDITYHRAKAHGTVRIAINRPECRNAFRPKTVDELFIALDHARQWSDVGCVLLTGNGPS
AKDGGWAFCSGGDQRIRGKDGYKYEGAEEGKADQARMGRLHILEVQRLIRFMPKVVIAVVPGWAVGGGHSLHVVCDLTLA
SKEHAIFKQTDPDVASFDSGYGSAYLAKMIGQKRAREIFFCGFNYSADEAFDMGMVNKSVPHAELETEALMWAKEINSKS
PTAMRMLKYGFNMTDDGMVGQQLFAGEATRLAYASAEAQEGRDAFLEKRDQDFSAFPWHY

Specific function: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) [H]

COG id: COG0447

COG function: function code H; Dihydroxynaphthoic acid synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=288, Percent_Identity=29.5138888888889, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI31542718, Length=266, Percent_Identity=29.3233082706767, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI1788597, Length=290, Percent_Identity=46.551724137931, Blast_Score=255, Evalue=2e-69,
Organism=Escherichia coli, GI1787659, Length=264, Percent_Identity=27.2727272727273, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI87082183, Length=254, Percent_Identity=26.3779527559055, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787660, Length=265, Percent_Identity=27.9245283018868, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI221142681, Length=271, Percent_Identity=25.4612546125461, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17554946, Length=254, Percent_Identity=27.5590551181102, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25145438, Length=268, Percent_Identity=27.9850746268657, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI20129971, Length=261, Percent_Identity=26.8199233716475, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24653477, Length=261, Percent_Identity=26.8199233716475, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24653139, Length=269, Percent_Identity=26.0223048327138, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR010198 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.1.3.36 [H]

Molecular weight: Translated: 33557; Mature: 33426

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQQVSDIFDPTLWDEVSGFQFDDITYHRAKAHGTVRIAINRPECRNAFRPKTVDELFIA
CCCCHHHHCCCHHHHHCCCCEECCCEEEEECCCCEEEEEEECCHHHCCCCCCHHHHHHHH
LDHARQWSDVGCVLLTGNGPSAKDGGWAFCSGGDQRIRGKDGYKYEGAEEGKADQARMGR
HHHHCCCCCCCEEEEECCCCCCCCCCEEEECCCCCEECCCCCCCCCCCCCCCCHHHHHCC
LHILEVQRLIRFMPKVVIAVVPGWAVGGGHSLHVVCDLTLASKEHAIFKQTDPDVASFDS
CHHHHHHHHHHHHHHHEEEECCCCEECCCCEEEEEEEEEECCCCCEEEECCCCCHHHCCC
GYGSAYLAKMIGQKRAREIFFCGFNYSADEAFDMGMVNKSVPHAELETEALMWAKEINSK
CCCHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHCCC
SPTAMRMLKYGFNMTDDGMVGQQLFAGEATRLAYASAEAQEGRDAFLEKRDQDFSAFPWH
CHHHHHHHHHCCCCCCCCCHHHHHHCCCHHHEEECCCHHHCCHHHHHHHCCCCCCCCCCC
Y
C
>Mature Secondary Structure 
TQQVSDIFDPTLWDEVSGFQFDDITYHRAKAHGTVRIAINRPECRNAFRPKTVDELFIA
CCCHHHHCCCHHHHHCCCCEECCCEEEEECCCCEEEEEEECCHHHCCCCCCHHHHHHHH
LDHARQWSDVGCVLLTGNGPSAKDGGWAFCSGGDQRIRGKDGYKYEGAEEGKADQARMGR
HHHHCCCCCCCEEEEECCCCCCCCCCEEEECCCCCEECCCCCCCCCCCCCCCCHHHHHCC
LHILEVQRLIRFMPKVVIAVVPGWAVGGGHSLHVVCDLTLASKEHAIFKQTDPDVASFDS
CHHHHHHHHHHHHHHHEEEECCCCEECCCCEEEEEEEEEECCCCCEEEECCCCCHHHCCC
GYGSAYLAKMIGQKRAREIFFCGFNYSADEAFDMGMVNKSVPHAELETEALMWAKEINSK
CCCHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHCCC
SPTAMRMLKYGFNMTDDGMVGQQLFAGEATRLAYASAEAQEGRDAFLEKRDQDFSAFPWH
CHHHHHHHHHCCCCCCCCCHHHHHHCCCHHHEEECCCHHHCCHHHHHHHCCCCCCCCCCC
Y
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]