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The map label for this gene is tas [H]

Identifier: 160876791

GI number: 160876791

Start: 4349487

End: 4350527

Strand: Direct

Name: tas [H]

Synonym: Sbal195_3686

Alternate gene names: 160876791

Gene position: 4349487-4350527 (Clockwise)

Preceding gene: 160876784

Following gene: 160876792

Centisome position: 81.34

GC content: 49.76

Gene sequence:

>1041_bases
ATGGAATACAGACGCATACCGCATTCTAATCTCGAGGTCAGCAAAATCTGTTTGGGCACTATGACTTGGGGCGAACAAAA
TACCCAAGCCGAAGCATTTGCACAGCTGGACTACGCCATAGGAAATGGCATCAACTTTATCGATACGGCGGAAATGTATC
CCGTCCCACCTAAGCCCGAAACCCAAGGGGAAACAGAGCGTATTCTTGGGCAATATATTAAGGCTCGCGGCAACCGTGAC
GATCTAGTTATTGCCACTAAAATTGCCGCACCGGGTGGTAAGAGTGATTATATTCGCAAGAATATGGCGCTGGACTGGAA
CAACATCCATCAAGCGGTCGATGCCTCCTTAGCGCGCCTCCAAATCGACACTATCGATCTTTATCAAATCCATTGGCCCG
ACCGAAATACCAACTTCTTTGGTGAACTGTTTTACGATCAACAGGATCAAGAACATCAAACCCCGATCCTCGAAACCCTT
GAAGCCCTCGCCGAAGTCATTCGCCAAGGTAAAGTGCGCTATATCGGTGTGTCGAACGAAACACCTTGGGGCTTGATGAA
GTACCTGCAACTCGCCGAAAAACACGGTCTGCCGCGTATTGTGAGTGTGCAAAACCCTTATAACTTGCTCAATCGCAGCT
TCGAAGTCGGCATGAGCGAAATCAGCCACCGCGAAAACCTGCCGCTGCTCGCTTACTCACCACTGGCCTTTGGCGCCTTA
ACCGGCAAATACTGCAACGACCAATGGCCCGAAGGTGCACGCCTGACCTTGTTTAAGCGTTTCGCCCGTTACACAGGTTC
GCAAATGGCACTGGAGGCCACGCAAGCCTACGTCGATTTAGCCCGCGAGTTCAAACTCACGCCCGCACAAATGGCGCTAG
CCTTTGTTAACTCACGTCAGTTTGTCGGCTCCAACATTATCGGCGCCACCGACTTGTATCAACTGAAAGAAAATATCGAC
AGCCTGAAAGTCACCTTATCGTCAGAGCTATTAGTGCGATTAAACGAACTATCCGATAAATTCAGATTACCTTGCCCTTA
G

Upstream 100 bases:

>100_bases
CTATTTTTAGCGCACTAACATTTCAACCTATGGTTTAACCTTTGCTTTACAGCAAAAGCTTGGTAGCCTCAAACTAAGAG
AGTTTTCGTAGGAGAAATAG

Downstream 100 bases:

>100_bases
CCCCCGAATCTTAGCCCCTAGGCTTAGTCGGCGAGTCGTTTGAATAATCAATAGCATCAGGCCAATCCCCCTGATGCTAT
TGATTTCATTCAGCTCAACG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MEYRRIPHSNLEVSKICLGTMTWGEQNTQAEAFAQLDYAIGNGINFIDTAEMYPVPPKPETQGETERILGQYIKARGNRD
DLVIATKIAAPGGKSDYIRKNMALDWNNIHQAVDASLARLQIDTIDLYQIHWPDRNTNFFGELFYDQQDQEHQTPILETL
EALAEVIRQGKVRYIGVSNETPWGLMKYLQLAEKHGLPRIVSVQNPYNLLNRSFEVGMSEISHRENLPLLAYSPLAFGAL
TGKYCNDQWPEGARLTLFKRFARYTGSQMALEATQAYVDLAREFKLTPAQMALAFVNSRQFVGSNIIGATDLYQLKENID
SLKVTLSSELLVRLNELSDKFRLPCP

Sequences:

>Translated_346_residues
MEYRRIPHSNLEVSKICLGTMTWGEQNTQAEAFAQLDYAIGNGINFIDTAEMYPVPPKPETQGETERILGQYIKARGNRD
DLVIATKIAAPGGKSDYIRKNMALDWNNIHQAVDASLARLQIDTIDLYQIHWPDRNTNFFGELFYDQQDQEHQTPILETL
EALAEVIRQGKVRYIGVSNETPWGLMKYLQLAEKHGLPRIVSVQNPYNLLNRSFEVGMSEISHRENLPLLAYSPLAFGAL
TGKYCNDQWPEGARLTLFKRFARYTGSQMALEATQAYVDLAREFKLTPAQMALAFVNSRQFVGSNIIGATDLYQLKENID
SLKVTLSSELLVRLNELSDKFRLPCP
>Mature_346_residues
MEYRRIPHSNLEVSKICLGTMTWGEQNTQAEAFAQLDYAIGNGINFIDTAEMYPVPPKPETQGETERILGQYIKARGNRD
DLVIATKIAAPGGKSDYIRKNMALDWNNIHQAVDASLARLQIDTIDLYQIHWPDRNTNFFGELFYDQQDQEHQTPILETL
EALAEVIRQGKVRYIGVSNETPWGLMKYLQLAEKHGLPRIVSVQNPYNLLNRSFEVGMSEISHRENLPLLAYSPLAFGAL
TGKYCNDQWPEGARLTLFKRFARYTGSQMALEATQAYVDLAREFKLTPAQMALAFVNSRQFVGSNIIGATDLYQLKENID
SLKVTLSSELLVRLNELSDKFRLPCP

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=348, Percent_Identity=31.3218390804598, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI4504825, Length=346, Percent_Identity=31.2138728323699, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI27436964, Length=332, Percent_Identity=30.7228915662651, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI27436962, Length=332, Percent_Identity=30.7228915662651, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI27436966, Length=332, Percent_Identity=30.421686746988, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI27436971, Length=335, Percent_Identity=28.955223880597, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI223718702, Length=349, Percent_Identity=26.3610315186246, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI41327764, Length=321, Percent_Identity=27.7258566978193, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI41152114, Length=321, Percent_Identity=26.791277258567, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1789199, Length=347, Percent_Identity=56.4841498559078, Blast_Score=399, Evalue=1e-112,
Organism=Escherichia coli, GI87081735, Length=345, Percent_Identity=31.304347826087, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1789375, Length=353, Percent_Identity=28.0453257790368, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788070, Length=306, Percent_Identity=28.1045751633987, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788081, Length=346, Percent_Identity=27.1676300578035, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323998, Length=345, Percent_Identity=26.3768115942029, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6319958, Length=318, Percent_Identity=26.4150943396226, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6325169, Length=355, Percent_Identity=27.0422535211268, Blast_Score=96, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6319951, Length=331, Percent_Identity=25.3776435045317, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6322615, Length=271, Percent_Identity=25.4612546125461, Blast_Score=83, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24646159, Length=228, Percent_Identity=31.140350877193, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24646155, Length=243, Percent_Identity=28.8065843621399, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 39268; Mature: 39268

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYRRIPHSNLEVSKICLGTMTWGEQNTQAEAFAQLDYAIGNGINFIDTAEMYPVPPKPE
CCCCCCCCCCCCHHHEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCC
TQGETERILGQYIKARGNRDDLVIATKIAAPGGKSDYIRKNMALDWNNIHQAVDASLARL
CCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHE
QIDTIDLYQIHWPDRNTNFFGELFYDQQDQEHQTPILETLEALAEVIRQGKVRYIGVSNE
EEEEEEEEEEECCCCCCCHHEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCC
TPWGLMKYLQLAEKHGLPRIVSVQNPYNLLNRSFEVGMSEISHRENLPLLAYSPLAFGAL
CCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHH
TGKYCNDQWPEGARLTLFKRFARYTGSQMALEATQAYVDLAREFKLTPAQMALAFVNSRQ
CCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCH
FVGSNIIGATDLYQLKENIDSLKVTLSSELLVRLNELSDKFRLPCP
HHCCCCCCHHHHHHHHHCHHHEEEEEHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEYRRIPHSNLEVSKICLGTMTWGEQNTQAEAFAQLDYAIGNGINFIDTAEMYPVPPKPE
CCCCCCCCCCCCHHHEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCC
TQGETERILGQYIKARGNRDDLVIATKIAAPGGKSDYIRKNMALDWNNIHQAVDASLARL
CCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHE
QIDTIDLYQIHWPDRNTNFFGELFYDQQDQEHQTPILETLEALAEVIRQGKVRYIGVSNE
EEEEEEEEEEECCCCCCCHHEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCC
TPWGLMKYLQLAEKHGLPRIVSVQNPYNLLNRSFEVGMSEISHRENLPLLAYSPLAFGAL
CCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHH
TGKYCNDQWPEGARLTLFKRFARYTGSQMALEATQAYVDLAREFKLTPAQMALAFVNSRQ
CCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCH
FVGSNIIGATDLYQLKENIDSLKVTLSSELLVRLNELSDKFRLPCP
HHCCCCCCHHHHHHHHHCHHHEEEEEHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]