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The map label for this gene is dinB [H]

Identifier: 160876658

GI number: 160876658

Start: 4175883

End: 4176959

Strand: Reverse

Name: dinB [H]

Synonym: Sbal195_3552

Alternate gene names: 160876658

Gene position: 4176959-4175883 (Counterclockwise)

Preceding gene: 160876659

Following gene: 160876656

Centisome position: 78.11

GC content: 49.58

Gene sequence:

>1077_bases
GTGCGAAAAATTATTCACATCGATATGGACTGCTATTTTGCGGCAGTGGAAATGCGCGACTTTCCCGAATACCGTGGCAA
GCCTTTAGCTGTGGGCGGCAGCAGCGATCGTCGTGGTGTTATCAGCACTTGCAGTTACGAGGCACGTAAATTCGGTGTGC
GTTCGGCGATGGCGACCGCTTATGCCTTTAAGTTGTGTCCCGATCTCATTTTGGTTCCTGGGCGGATGCAGGTTTATAAA
GAGGTGTCGCTGCAAATTCGTGAAATTTTCTCCCGCTATACCCCATTGATTGAGCCGCTTTCTTTAGATGAAGCCTATTT
AGACGTGAGTGAGTGCCAACAATATAAGGGCTCGGCGACCTTGATTGCGCAGGCCATTCGCCGCGATATCTTAGCCGAAA
CTGGGTTAACCGCTTCGGCAGGCATAGCACCGGTGAAGTTTTTGGCTAAAGTTGCCTCGGATTTGAATAAGCCAAACGGC
CAATATGTGATTACCCCAGAGACACTCCCTGATTTTGTTAAAACCTTATCGCTGCGTAAAATTCCCGGTGTTGGCAAAGT
CACCGCCGAAAAGCTCTCCTCGCTTGGTCTCAATACCTGTGGTGATGTGCAAGCCTATTCTAAACCTGAGTTATTGGCGC
GATTCGGCAAGTTTGGTGGTGTCTTGATTGAGCGTTCCCAAGGAATTGATGAGCGGGGCATTTCCGCCGATAGGGAGCGT
AAATCAGTCGGTGTTGAAACTACGCTGGCGAAGGATATTTATAGTCTAGAGCAGTGCCAGCAAGTGATGCCAGGGTTGAT
CCAAGAATTAGCCCTACGTTTGAGCCGCAGCGCTAAAGAGCGCAAAATTCACAAGCAAGTGGTCAAGCTCAAGTTTAATG
ATTTCAAGCAAACCACTATCGAGCATCGTAGCGATGAAGTCTCGATTGTGATGTTTTATGATCTACTCGCACAGGCGATG
GCAAGGCAAGAGGGCCGCGGCATTCGCCTATTAGGTATTTCGGTCGGCCTCGCCGATTCTATCCTCGCAGTGCCCGAAAT
CCCAAATGCCCAGACTCAGCTTGATTTAGCGCTCTAG

Upstream 100 bases:

>100_bases
CCTTTTTATTTTAGGTTTCCCGCCTGATCCTCGCTAAATTGATGACGAACACTTGATTACTGTTTTTATATACAGTATTT
TGGCGTTGGAGGAATTCAAC

Downstream 100 bases:

>100_bases
CGTTTACTGAGTCGATACGCCGCAGACTCATGTCTGAATGGCTCAATAAGCCTCGGGTGGATTTGCCAACATAAAATCAA
TTAACAGTCTGACCCGCAAG

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MRKIIHIDMDCYFAAVEMRDFPEYRGKPLAVGGSSDRRGVISTCSYEARKFGVRSAMATAYAFKLCPDLILVPGRMQVYK
EVSLQIREIFSRYTPLIEPLSLDEAYLDVSECQQYKGSATLIAQAIRRDILAETGLTASAGIAPVKFLAKVASDLNKPNG
QYVITPETLPDFVKTLSLRKIPGVGKVTAEKLSSLGLNTCGDVQAYSKPELLARFGKFGGVLIERSQGIDERGISADRER
KSVGVETTLAKDIYSLEQCQQVMPGLIQELALRLSRSAKERKIHKQVVKLKFNDFKQTTIEHRSDEVSIVMFYDLLAQAM
ARQEGRGIRLLGISVGLADSILAVPEIPNAQTQLDLAL

Sequences:

>Translated_358_residues
MRKIIHIDMDCYFAAVEMRDFPEYRGKPLAVGGSSDRRGVISTCSYEARKFGVRSAMATAYAFKLCPDLILVPGRMQVYK
EVSLQIREIFSRYTPLIEPLSLDEAYLDVSECQQYKGSATLIAQAIRRDILAETGLTASAGIAPVKFLAKVASDLNKPNG
QYVITPETLPDFVKTLSLRKIPGVGKVTAEKLSSLGLNTCGDVQAYSKPELLARFGKFGGVLIERSQGIDERGISADRER
KSVGVETTLAKDIYSLEQCQQVMPGLIQELALRLSRSAKERKIHKQVVKLKFNDFKQTTIEHRSDEVSIVMFYDLLAQAM
ARQEGRGIRLLGISVGLADSILAVPEIPNAQTQLDLAL
>Mature_358_residues
MRKIIHIDMDCYFAAVEMRDFPEYRGKPLAVGGSSDRRGVISTCSYEARKFGVRSAMATAYAFKLCPDLILVPGRMQVYK
EVSLQIREIFSRYTPLIEPLSLDEAYLDVSECQQYKGSATLIAQAIRRDILAETGLTASAGIAPVKFLAKVASDLNKPNG
QYVITPETLPDFVKTLSLRKIPGVGKVTAEKLSSLGLNTCGDVQAYSKPELLARFGKFGGVLIERSQGIDERGISADRER
KSVGVETTLAKDIYSLEQCQQVMPGLIQELALRLSRSAKERKIHKQVVKLKFNDFKQTTIEHRSDEVSIVMFYDLLAQAM
ARQEGRGIRLLGISVGLADSILAVPEIPNAQTQLDLAL

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI7706681, Length=325, Percent_Identity=32, Blast_Score=170, Evalue=1e-42,
Organism=Homo sapiens, GI84043967, Length=324, Percent_Identity=32.0987654320988, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI154350220, Length=249, Percent_Identity=33.3333333333333, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI7705344, Length=108, Percent_Identity=50, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI5729982, Length=141, Percent_Identity=41.1347517730496, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1786425, Length=362, Percent_Identity=58.5635359116022, Blast_Score=406, Evalue=1e-114,
Organism=Escherichia coli, GI1787432, Length=207, Percent_Identity=25.1207729468599, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17537959, Length=282, Percent_Identity=29.0780141843972, Blast_Score=131, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI193205700, Length=394, Percent_Identity=28.4263959390863, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI115534089, Length=359, Percent_Identity=24.7910863509749, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193205702, Length=332, Percent_Identity=26.2048192771084, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324921, Length=207, Percent_Identity=29.4685990338164, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19923006, Length=323, Percent_Identity=30.6501547987616, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI21355641, Length=284, Percent_Identity=29.9295774647887, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24644984, Length=284, Percent_Identity=29.9295774647887, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24668444, Length=123, Percent_Identity=36.5853658536585, Blast_Score=81, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 39581; Mature: 39581

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIIHIDMDCYFAAVEMRDFPEYRGKPLAVGGSSDRRGVISTCSYEARKFGVRSAMATA
CCEEEEECCCCEEEHHHHHHCHHHCCCEEEECCCCCCCCCHHHCCHHHHHHHHHHHHHHH
YAFKLCPDLILVPGRMQVYKEVSLQIREIFSRYTPLIEPLSLDEAYLDVSECQQYKGSAT
HHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHCCCHHH
LIAQAIRRDILAETGLTASAGIAPVKFLAKVASDLNKPNGQYVITPETLPDFVKTLSLRK
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHC
IPGVGKVTAEKLSSLGLNTCGDVQAYSKPELLARFGKFGGVLIERSQGIDERGISADRER
CCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCCCCCCCCCHHH
KSVGVETTLAKDIYSLEQCQQVMPGLIQELALRLSRSAKERKIHKQVVKLKFNDFKQTTI
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EHRSDEVSIVMFYDLLAQAMARQEGRGIRLLGISVGLADSILAVPEIPNAQTQLDLAL
HCCCCCEEEHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHEECCCCCCCCCCEEECC
>Mature Secondary Structure
MRKIIHIDMDCYFAAVEMRDFPEYRGKPLAVGGSSDRRGVISTCSYEARKFGVRSAMATA
CCEEEEECCCCEEEHHHHHHCHHHCCCEEEECCCCCCCCCHHHCCHHHHHHHHHHHHHHH
YAFKLCPDLILVPGRMQVYKEVSLQIREIFSRYTPLIEPLSLDEAYLDVSECQQYKGSAT
HHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHCCCHHH
LIAQAIRRDILAETGLTASAGIAPVKFLAKVASDLNKPNGQYVITPETLPDFVKTLSLRK
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHC
IPGVGKVTAEKLSSLGLNTCGDVQAYSKPELLARFGKFGGVLIERSQGIDERGISADRER
CCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCCCCCCCCCHHH
KSVGVETTLAKDIYSLEQCQQVMPGLIQELALRLSRSAKERKIHKQVVKLKFNDFKQTTI
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EHRSDEVSIVMFYDLLAQAMARQEGRGIRLLGISVGLADSILAVPEIPNAQTQLDLAL
HCCCCCEEEHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHEECCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA