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The map label for this gene is aaeR [H]

Identifier: 160876413

GI number: 160876413

Start: 3898807

End: 3899751

Strand: Reverse

Name: aaeR [H]

Synonym: Sbal195_3307

Alternate gene names: 160876413

Gene position: 3899751-3898807 (Counterclockwise)

Preceding gene: 160876421

Following gene: 160876411

Centisome position: 72.93

GC content: 52.59

Gene sequence:

>945_bases
ATGGATAGACTAGAAGCGGCTAAAGTGTTTGTCACTATTGTCGAGCGCGGCAGCATGATCAGCGCCGCTAATGCTTTAGA
TATGTCGCGTTCTATGGTGACCCGTTACTTGAGCGAAATGGAAGAATGGTCCGGTGCTAGATTGTTGCATCGTTCGACGC
GCAGCCTCAGCTTAACGCCAGCGGGTGAGCAAGTGCTGGATTACTGCCATCGACTGCTCGAACTGGCGAACGAAGTGCCA
GCGGTGAGTCATGCTTCGGTGGCGATTCCGCGCGGATTATTGCGCATTAGCTGCTCCCAGTTTTTGGCGCATCAGATTTT
AGCGCCCGTGGTGCGCCAATACTTAGCCAGTTATCCGCAGGCGAGTGTGAATATCCACGTGAGTAGCCAAACTGTCGATC
TGGTCGCCGAGCGGATTGATCTTGCGATTCGCATCACCAATGAACTCGATCCCAATCTTATCGCAAGGCGCTTGGGGGAA
TGTGAATCTGTGGTGTGCGCTGCACCGAGTTATCTTGCCGCGCGTGCCGCCGTGGTGCATCCCGAGGATTTAACTCAGCA
TAATTGCTTAACCTATTCCTACTTTGGCGATGTGATGTGGCGGTTTTATCAAGCCGATGTGGCTGCGAAACAGGCTCAGG
CGCCGAACTCCGATCCTAAGTTAAACCAAGGGCAGGCGTTTAATGTGCCTGTGAATGGTAATTTTAGCGCCAATGATTCC
ATGGTGGTGCTCAATGCCACGCTGGCAGGTGAGGGGATTGCAATGCAACCGCTGTGGGCGGCGAAACCCTATTTAGATTC
GGGTCAGTTAGTGCCTTTGTTAACTGAGTTCATGCCGCAGTCACTGGGTGTGTATGGCGTGTATCAATCCCGCAAACATA
TGCAGCCTGCACTCAGGGTGATGATGGACATGCTGGTGGCCTATTTTGCCAGCTTGAAAAGCTGA

Upstream 100 bases:

>100_bases
GCCGGGTGTACTCTTAGTTATTATTCATGTGGGGCGCGAGTATGTGAGTGAGCCTTCGAGTGATTGAAAGTTATTGATTG
AACGTGAGTGGAGATAAACC

Downstream 100 bases:

>100_bases
GTTGTTTTATCGGAACTATTCGACAGCATCCAATAAAAACAAGTCGATAAAGCGAGTCCAGAAAAACTATTCATAAAAAC
TTCCCCATAAAAAGCATCCA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MDRLEAAKVFVTIVERGSMISAANALDMSRSMVTRYLSEMEEWSGARLLHRSTRSLSLTPAGEQVLDYCHRLLELANEVP
AVSHASVAIPRGLLRISCSQFLAHQILAPVVRQYLASYPQASVNIHVSSQTVDLVAERIDLAIRITNELDPNLIARRLGE
CESVVCAAPSYLAARAAVVHPEDLTQHNCLTYSYFGDVMWRFYQADVAAKQAQAPNSDPKLNQGQAFNVPVNGNFSANDS
MVVLNATLAGEGIAMQPLWAAKPYLDSGQLVPLLTEFMPQSLGVYGVYQSRKHMQPALRVMMDMLVAYFASLKS

Sequences:

>Translated_314_residues
MDRLEAAKVFVTIVERGSMISAANALDMSRSMVTRYLSEMEEWSGARLLHRSTRSLSLTPAGEQVLDYCHRLLELANEVP
AVSHASVAIPRGLLRISCSQFLAHQILAPVVRQYLASYPQASVNIHVSSQTVDLVAERIDLAIRITNELDPNLIARRLGE
CESVVCAAPSYLAARAAVVHPEDLTQHNCLTYSYFGDVMWRFYQADVAAKQAQAPNSDPKLNQGQAFNVPVNGNFSANDS
MVVLNATLAGEGIAMQPLWAAKPYLDSGQLVPLLTEFMPQSLGVYGVYQSRKHMQPALRVMMDMLVAYFASLKS
>Mature_314_residues
MDRLEAAKVFVTIVERGSMISAANALDMSRSMVTRYLSEMEEWSGARLLHRSTRSLSLTPAGEQVLDYCHRLLELANEVP
AVSHASVAIPRGLLRISCSQFLAHQILAPVVRQYLASYPQASVNIHVSSQTVDLVAERIDLAIRITNELDPNLIARRLGE
CESVVCAAPSYLAARAAVVHPEDLTQHNCLTYSYFGDVMWRFYQADVAAKQAQAPNSDPKLNQGQAFNVPVNGNFSANDS
MVVLNATLAGEGIAMQPLWAAKPYLDSGQLVPLLTEFMPQSLGVYGVYQSRKHMQPALRVMMDMLVAYFASLKS

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=312, Percent_Identity=33.0128205128205, Blast_Score=154, Evalue=9e-39,
Organism=Escherichia coli, GI87081978, Length=312, Percent_Identity=29.4871794871795, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1789440, Length=306, Percent_Identity=29.4117647058824, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1787589, Length=308, Percent_Identity=25.974025974026, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1786401, Length=306, Percent_Identity=27.4509803921569, Blast_Score=111, Evalue=8e-26,
Organism=Escherichia coli, GI145693193, Length=308, Percent_Identity=26.9480519480519, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787128, Length=300, Percent_Identity=25.3333333333333, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789173, Length=269, Percent_Identity=25.2788104089219, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786448, Length=295, Percent_Identity=25.0847457627119, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34572; Mature: 34572

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRLEAAKVFVTIVERGSMISAANALDMSRSMVTRYLSEMEEWSGARLLHRSTRSLSLTP
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEECCC
AGEQVLDYCHRLLELANEVPAVSHASVAIPRGLLRISCSQFLAHQILAPVVRQYLASYPQ
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ASVNIHVSSQTVDLVAERIDLAIRITNELDPNLIARRLGECESVVCAAPSYLAARAAVVH
CEEEEEECCHHHHHHHHHHHEEEEECCCCCHHHHHHHHCCHHHHHHCCCHHHHHHHHEEC
PEDLTQHNCLTYSYFGDVMWRFYQADVAAKQAQAPNSDPKLNQGQAFNVPVNGNFSANDS
CHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCC
MVVLNATLAGEGIAMQPLWAAKPYLDSGQLVPLLTEFMPQSLGVYGVYQSRKHMQPALRV
EEEEEEEECCCCCEECCHHCCCCCCCCCCHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHH
MMDMLVAYFASLKS
HHHHHHHHHHHHCC
>Mature Secondary Structure
MDRLEAAKVFVTIVERGSMISAANALDMSRSMVTRYLSEMEEWSGARLLHRSTRSLSLTP
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEECCC
AGEQVLDYCHRLLELANEVPAVSHASVAIPRGLLRISCSQFLAHQILAPVVRQYLASYPQ
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ASVNIHVSSQTVDLVAERIDLAIRITNELDPNLIARRLGECESVVCAAPSYLAARAAVVH
CEEEEEECCHHHHHHHHHHHEEEEECCCCCHHHHHHHHCCHHHHHHCCCHHHHHHHHEEC
PEDLTQHNCLTYSYFGDVMWRFYQADVAAKQAQAPNSDPKLNQGQAFNVPVNGNFSANDS
CHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCC
MVVLNATLAGEGIAMQPLWAAKPYLDSGQLVPLLTEFMPQSLGVYGVYQSRKHMQPALRV
EEEEEEEECCCCCEECCHHCCCCCCCCCCHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHH
MMDMLVAYFASLKS
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]