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The map label for this gene is gpwA [H]

Identifier: 160876286

GI number: 160876286

Start: 3752211

End: 3752750

Strand: Reverse

Name: gpwA [H]

Synonym: Sbal195_3180

Alternate gene names: 160876286

Gene position: 3752750-3752211 (Counterclockwise)

Preceding gene: 160876287

Following gene: 160876285

Centisome position: 70.18

GC content: 42.41

Gene sequence:

>540_bases
ATGAAAAAATTACCTATGATATTCGCTATGACTGCGAGCTTGATGAGTGTTAGCGCTATGGCGGCCACTTGTCCCGAGTA
TTTGAACCTTGAAGTACGAAAATTACATTCTGAAGAGACAGTTAATCTGTGTGAATTGACTCAGGGAAAGCCAGTGTTGA
TTGTTAACACTGCAAGTAACTGTGGTTACACCCCGCAGTTTAAAGCGCTCGAAGCATTGCATGAAAACTATAAAGACAAA
GGCTTAGTGGTTATTGGTTTCCCATCGGATGATTTTTTCCAAGAAGAAAATGATGAGAAAGACACGGCTAAGGTGTGTTA
CATCAATTACGGTGTCACTTTCACTATGTTGTCGACTTCGGCTGTGCGTGGCAGTGACGCCAATAGCGTATTTAAATACT
TAGCCGAGAAAACCGGTGCGCCTAAGTGGAATTTCTACAAGTATGTCGTTAGCGGCGATGGCGCGGTTGTGCAACAGTTC
AATTCTAAAGTGAAGCCAGATAGCGAAGAGCTTAAGCAAGCAATAGAATCTGTACTTTAA

Upstream 100 bases:

>100_bases
ACTTCATCGCTATGCGGTCGTTAACCATAGCTTTTATTTTTTAATTCAATATGATCTTTACCTAGTACGTTTACGTAATG
TACCGGTAAAGGAGAAAGCA

Downstream 100 bases:

>100_bases
TCTTATAAGTATTTATTAATTAAGAGGCTGTTTTGGCTAAATTTTCAGGCTTATCCAAAGAAGTTGGACACGGACAACGC
GGCAAAGTGGGCGTGCTGTT

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MKKLPMIFAMTASLMSVSAMAATCPEYLNLEVRKLHSEETVNLCELTQGKPVLIVNTASNCGYTPQFKALEALHENYKDK
GLVVIGFPSDDFFQEENDEKDTAKVCYINYGVTFTMLSTSAVRGSDANSVFKYLAEKTGAPKWNFYKYVVSGDGAVVQQF
NSKVKPDSEELKQAIESVL

Sequences:

>Translated_179_residues
MKKLPMIFAMTASLMSVSAMAATCPEYLNLEVRKLHSEETVNLCELTQGKPVLIVNTASNCGYTPQFKALEALHENYKDK
GLVVIGFPSDDFFQEENDEKDTAKVCYINYGVTFTMLSTSAVRGSDANSVFKYLAEKTGAPKWNFYKYVVSGDGAVVQQF
NSKVKPDSEELKQAIESVL
>Mature_179_residues
MKKLPMIFAMTASLMSVSAMAATCPEYLNLEVRKLHSEETVNLCELTQGKPVLIVNTASNCGYTPQFKALEALHENYKDK
GLVVIGFPSDDFFQEENDEKDTAKVCYINYGVTFTMLSTSAVRGSDANSVFKYLAEKTGAPKWNFYKYVVSGDGAVVQQF
NSKVKPDSEELKQAIESVL

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=138, Percent_Identity=37.6811594202899, Blast_Score=89, Evalue=1e-18,
Organism=Homo sapiens, GI192455698, Length=145, Percent_Identity=31.0344827586207, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI4557629, Length=141, Percent_Identity=31.2056737588652, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1788003, Length=165, Percent_Identity=31.5151515151515, Blast_Score=87, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17535473, Length=139, Percent_Identity=33.8129496402878, Blast_Score=73, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17506887, Length=137, Percent_Identity=32.8467153284672, Blast_Score=67, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6319721, Length=139, Percent_Identity=47.4820143884892, Blast_Score=124, Evalue=7e-30,
Organism=Saccharomyces cerevisiae, GI6322228, Length=139, Percent_Identity=43.8848920863309, Blast_Score=117, Evalue=9e-28,
Organism=Saccharomyces cerevisiae, GI6322826, Length=139, Percent_Identity=42.4460431654676, Blast_Score=100, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24656772, Length=146, Percent_Identity=32.1917808219178, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24656767, Length=146, Percent_Identity=32.1917808219178, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24656777, Length=146, Percent_Identity=32.1917808219178, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 19849; Mature: 19849

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLPMIFAMTASLMSVSAMAATCPEYLNLEVRKLHSEETVNLCELTQGKPVLIVNTASN
CCCCCHHHHHHHHHHHHHHHHHHCHHHHCHHHHHHCCCCCCHHHHCCCCCCEEEEECCCC
CGYTPQFKALEALHENYKDKGLVVIGFPSDDFFQEENDEKDTAKVCYINYGVTFTMLSTS
CCCCCCHHHHHHHHHCCCCCCEEEEECCCCHHHCCCCCCCCCEEEEEEECCEEEEEEEHH
AVRGSDANSVFKYLAEKTGAPKWNFYKYVVSGDGAVVQQFNSKVKPDSEELKQAIESVL
HCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKKLPMIFAMTASLMSVSAMAATCPEYLNLEVRKLHSEETVNLCELTQGKPVLIVNTASN
CCCCCHHHHHHHHHHHHHHHHHHCHHHHCHHHHHHCCCCCCHHHHCCCCCCEEEEECCCC
CGYTPQFKALEALHENYKDKGLVVIGFPSDDFFQEENDEKDTAKVCYINYGVTFTMLSTS
CCCCCCHHHHHHHHHCCCCCCEEEEECCCCHHHCCCCCCCCCEEEEEEECCEEEEEEEHH
AVRGSDANSVFKYLAEKTGAPKWNFYKYVVSGDGAVVQQFNSKVKPDSEELKQAIESVL
HCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA