Click here to switch to the map view.

The map label for this gene is tadA [H]

Identifier: 160876246

GI number: 160876246

Start: 3712315

End: 3712842

Strand: Reverse

Name: tadA [H]

Synonym: Sbal195_3140

Alternate gene names: 160876246

Gene position: 3712842-3712315 (Counterclockwise)

Preceding gene: 160876247

Following gene: 160876244

Centisome position: 69.43

GC content: 51.14

Gene sequence:

>528_bases
GTGGATCAAACGCAGCAAAATGAACAATCGCAGCAAGACGAGCAATGGATGCAAGTCGCGATGCTGATGGCCGAGAAAGC
CGAAGCTGAGGGCGAAGTGCCTGTGGGGGCGGTATTGGTCAAAGACGGCCAGCAAATTGCGACCGGTTACAATTTATCCA
TTAGTCAGCACGATCCTAGCGCCCATGCGGAAATTTTATGTTTACGGGAAGCGGGGCGTTTGGTCGAAAACTATCGCCTG
TTAGACGCGACTTTATATGTCACGCTTGAACCTTGTGCTATGTGTGCAGGTGCCATGGTGCACAGCCGGATCGCGCGGGT
GGTTTTTGGTGCTCGGGATGAAAAAACCGGTGCAGCGGGGACTGTAGTGAATTTACTGCAACACCCGGCATTTAATCATC
AAGTTGAAGTGACATCGGGTGTATTGGCCGACGCCTGTAGCGCGCAATTGAGTCGTTTTTTTAAACGGCGTAGAAAGGAG
AAAAAAGCCCTGAAACAGGCTCAAAAGGCGCAGCAAGCGATTGAGTAA

Upstream 100 bases:

>100_bases
TTTGATAGATTAACTTAAGTTGAATGACTCAACCGTGAAATATCTGTGTTTGACTGATATAATCCGGCATTATTTTTTGG
CTAATCGGTAGAGGGCATGA

Downstream 100 bases:

>100_bases
ACAGCGGTAAAAGCGACAGGATTAATCCTGAGACTGAATAAAAGTAAAGAACAGTTTCTGACGATTCAAAATACGACGAT
GGCGAACTTTAAGTAAAGTA

Product: zinc-binding CMP/dCMP deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MDQTQQNEQSQQDEQWMQVAMLMAEKAEAEGEVPVGAVLVKDGQQIATGYNLSISQHDPSAHAEILCLREAGRLVENYRL
LDATLYVTLEPCAMCAGAMVHSRIARVVFGARDEKTGAAGTVVNLLQHPAFNHQVEVTSGVLADACSAQLSRFFKRRRKE
KKALKQAQKAQQAIE

Sequences:

>Translated_175_residues
MDQTQQNEQSQQDEQWMQVAMLMAEKAEAEGEVPVGAVLVKDGQQIATGYNLSISQHDPSAHAEILCLREAGRLVENYRL
LDATLYVTLEPCAMCAGAMVHSRIARVVFGARDEKTGAAGTVVNLLQHPAFNHQVEVTSGVLADACSAQLSRFFKRRRKE
KKALKQAQKAQQAIE
>Mature_175_residues
MDQTQQNEQSQQDEQWMQVAMLMAEKAEAEGEVPVGAVLVKDGQQIATGYNLSISQHDPSAHAEILCLREAGRLVENYRL
LDATLYVTLEPCAMCAGAMVHSRIARVVFGARDEKTGAAGTVVNLLQHPAFNHQVEVTSGVLADACSAQLSRFFKRRRKE
KKALKQAQKAQQAIE

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=174, Percent_Identity=29.8850574712644, Blast_Score=81, Evalue=5e-16,
Organism=Escherichia coli, GI145693172, Length=157, Percent_Identity=61.1464968152866, Blast_Score=213, Evalue=4e-57,
Organism=Escherichia coli, GI1786616, Length=155, Percent_Identity=31.6129032258064, Blast_Score=60, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17541138, Length=169, Percent_Identity=32.5443786982249, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17554608, Length=107, Percent_Identity=36.4485981308411, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6325319, Length=103, Percent_Identity=38.8349514563107, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322425, Length=172, Percent_Identity=30.8139534883721, Blast_Score=67, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21355527, Length=147, Percent_Identity=32.6530612244898, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 19264; Mature: 19264

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQTQQNEQSQQDEQWMQVAMLMAEKAEAEGEVPVGAVLVKDGQQIATGYNLSISQHDPS
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHCCCCEEECCCCCC
AHAEILCLREAGRLVENYRLLDATLYVTLEPCAMCAGAMVHSRIARVVFGARDEKTGAAG
CHHHHHHHHHHHHHHHHHHHHHEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
TVVNLLQHPAFNHQVEVTSGVLADACSAQLSRFFKRRRKEKKALKQAQKAQQAIE
HHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDQTQQNEQSQQDEQWMQVAMLMAEKAEAEGEVPVGAVLVKDGQQIATGYNLSISQHDPS
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHCCCCEEECCCCCC
AHAEILCLREAGRLVENYRLLDATLYVTLEPCAMCAGAMVHSRIARVVFGARDEKTGAAG
CHHHHHHHHHHHHHHHHHHHHHEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
TVVNLLQHPAFNHQVEVTSGVLADACSAQLSRFFKRRRKEKKALKQAQKAQQAIE
HHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]