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The map label for this gene is eryC1 [H]

Identifier: 160876135

GI number: 160876135

Start: 3595867

End: 3596970

Strand: Reverse

Name: eryC1 [H]

Synonym: Sbal195_3026

Alternate gene names: 160876135

Gene position: 3596970-3595867 (Counterclockwise)

Preceding gene: 160876136

Following gene: 160876134

Centisome position: 67.27

GC content: 43.48

Gene sequence:

>1104_bases
ATGATTAACTTCCTTGATTTAAAAGCTATTAACAACCAATACCAGCAAGAGCTAAAAGAAGCTTGTGCACGAGTGATAGA
TTCTGGTTGGTATATTATGGGCAATGAGCTTGCCCAATTTGAAACCGAATTTGCCGCTTATTGCGGCACAAAGCATTCAA
TTGGCGTGGCCAATGGTCTCGATGCACTTATTCTCACTTTGCGCGCTTGGAAGGTGCTGGGCAAACTGCAAGCCGGCGAT
GAAGTGATTGTGCAGGCTAATACTTATATTGCCTCTGTGTTGGCAATTACCGAGAATGATCTCGTGCCAGTATTGGTAGA
GCCAAACCCTGGTAGCTATAACCTCGACCCCGAAACGCTCGCCGCGGCTATTACTCCCAAGACTAAGGTGATTTTACCAG
TTCATCTTTATGGACAGTTGTCGCCGATGCCAGAAATTATGGCGATAGCCTGTGCACATAATCTACTCGTATTGGAAGAT
TGTGCCCAATCACACGGTGCTGAAATTAACGGTAAACGCGCCGGAAACTGGGGTGATGCGGCAGGCTTTAGCTTTTATCC
GGGTAAAAACTTGGGAGCACTCGGTGATGCTGGTGCAATTACCACAAATGATGATGAGTTAGCGCAAACTCTTAAAGCCT
TAAGGAATTATGGTTCTCATAAAAAGTACGAGAACCTCTATCAAGGGGTTAATAGCCGTCTTGATGAAATTCAAGCTGCA
ATGTTACGAGTTAAATTGCGCCATTTAGATAGCGAAACCGCTCGCCGTCAGCATATTGCTCAAACTTATCGCACTAATAT
CAGCAACCCATTAATTACGCTGCCACAAGTGAATGAAGAACTTGCTCACGTTTGGCATTTATTTGTTGTGAGTTGTGAAC
AGCGAGAAGTTTTGCAACAATTTTTAGCTTCAAGAGGTATTCAAACTTTAATTCATTATCCAATCCCCCCACATAAACAG
CACGCTTATAGTCATTATGCTGATTTGCAATTGCCACTAACTGAGTTAATTCATCAGCAAGTACTTTCTATTCCGCTTGA
TCCTACCATGAGTGATGCGGCGGTTAAGCAAGTTATTGCCGCAATGAATGAGTTTGCTGGATGA

Upstream 100 bases:

>100_bases
GCTATGGTGGGTGCAGGTTCTGTAGTGACTAAAGATGTGCCAGCATACGCTGTAGTTGTTGGTAACCCAGCCAGAATCAT
TAAATATATAGAGCAGTAAC

Downstream 100 bases:

>100_bases
AGCGTTTGCTCAAAGTCACCGCCATGACCGGGTTATTAACCTTATTGCGCATGGCGATGGGATTTGTGATTGCCAAGGTA
GTGGCCATCTATACCGGCCC

Product: DegT/DnrJ/EryC1/StrS aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MINFLDLKAINNQYQQELKEACARVIDSGWYIMGNELAQFETEFAAYCGTKHSIGVANGLDALILTLRAWKVLGKLQAGD
EVIVQANTYIASVLAITENDLVPVLVEPNPGSYNLDPETLAAAITPKTKVILPVHLYGQLSPMPEIMAIACAHNLLVLED
CAQSHGAEINGKRAGNWGDAAGFSFYPGKNLGALGDAGAITTNDDELAQTLKALRNYGSHKKYENLYQGVNSRLDEIQAA
MLRVKLRHLDSETARRQHIAQTYRTNISNPLITLPQVNEELAHVWHLFVVSCEQREVLQQFLASRGIQTLIHYPIPPHKQ
HAYSHYADLQLPLTELIHQQVLSIPLDPTMSDAAVKQVIAAMNEFAG

Sequences:

>Translated_367_residues
MINFLDLKAINNQYQQELKEACARVIDSGWYIMGNELAQFETEFAAYCGTKHSIGVANGLDALILTLRAWKVLGKLQAGD
EVIVQANTYIASVLAITENDLVPVLVEPNPGSYNLDPETLAAAITPKTKVILPVHLYGQLSPMPEIMAIACAHNLLVLED
CAQSHGAEINGKRAGNWGDAAGFSFYPGKNLGALGDAGAITTNDDELAQTLKALRNYGSHKKYENLYQGVNSRLDEIQAA
MLRVKLRHLDSETARRQHIAQTYRTNISNPLITLPQVNEELAHVWHLFVVSCEQREVLQQFLASRGIQTLIHYPIPPHKQ
HAYSHYADLQLPLTELIHQQVLSIPLDPTMSDAAVKQVIAAMNEFAG
>Mature_367_residues
MINFLDLKAINNQYQQELKEACARVIDSGWYIMGNELAQFETEFAAYCGTKHSIGVANGLDALILTLRAWKVLGKLQAGD
EVIVQANTYIASVLAITENDLVPVLVEPNPGSYNLDPETLAAAITPKTKVILPVHLYGQLSPMPEIMAIACAHNLLVLED
CAQSHGAEINGKRAGNWGDAAGFSFYPGKNLGALGDAGAITTNDDELAQTLKALRNYGSHKKYENLYQGVNSRLDEIQAA
MLRVKLRHLDSETARRQHIAQTYRTNISNPLITLPQVNEELAHVWHLFVVSCEQREVLQQFLASRGIQTLIHYPIPPHKQ
HAYSHYADLQLPLTELIHQQVLSIPLDPTMSDAAVKQVIAAMNEFAG

Specific function: Sensor protein that transfers the signal of environmental stimuli to the regulatory region of target genes to activate or repress transcription of erythromycin biosynthesis genes (Potential) [H]

COG id: COG0399

COG function: function code M; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the degT/dnrJ/eryC1 family [H]

Homologues:

Organism=Escherichia coli, GI145693159, Length=368, Percent_Identity=30.7065217391304, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI2367285, Length=316, Percent_Identity=30.379746835443, Blast_Score=125, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000653
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01041 DegT_DnrJ_EryC1 [H]

EC number: NA

Molecular weight: Translated: 40495; Mature: 40495

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINFLDLKAINNQYQQELKEACARVIDSGWYIMGNELAQFETEFAAYCGTKHSIGVANGL
CCCEEHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHCCCCCCCCCCCCH
DALILTLRAWKVLGKLQAGDEVIVQANTYIASVLAITENDLVPVLVEPNPGSYNLDPETL
HHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHEECCCCEEEEECCCCCCCCCCHHHH
AAAITPKTKVILPVHLYGQLSPMPEIMAIACAHNLLVLEDCAQSHGAEINGKRAGNWGDA
HHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCCCCC
AGFSFYPGKNLGALGDAGAITTNDDELAQTLKALRNYGSHKKYENLYQGVNSRLDEIQAA
CCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
MLRVKLRHLDSETARRQHIAQTYRTNISNPLITLPQVNEELAHVWHLFVVSCEQREVLQQ
HHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHCCHHHHHHHH
FLASRGIQTLIHYPIPPHKQHAYSHYADLQLPLTELIHQQVLSIPLDPTMSDAAVKQVIA
HHHHCCCHHEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHH
AMNEFAG
HHHHHCC
>Mature Secondary Structure
MINFLDLKAINNQYQQELKEACARVIDSGWYIMGNELAQFETEFAAYCGTKHSIGVANGL
CCCEEHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHCCCCCCCCCCCCH
DALILTLRAWKVLGKLQAGDEVIVQANTYIASVLAITENDLVPVLVEPNPGSYNLDPETL
HHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHEECCCCEEEEECCCCCCCCCCHHHH
AAAITPKTKVILPVHLYGQLSPMPEIMAIACAHNLLVLEDCAQSHGAEINGKRAGNWGDA
HHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCCCCC
AGFSFYPGKNLGALGDAGAITTNDDELAQTLKALRNYGSHKKYENLYQGVNSRLDEIQAA
CCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
MLRVKLRHLDSETARRQHIAQTYRTNISNPLITLPQVNEELAHVWHLFVVSCEQREVLQQ
HHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHCCHHHHHHHH
FLASRGIQTLIHYPIPPHKQHAYSHYADLQLPLTELIHQQVLSIPLDPTMSDAAVKQVIA
HHHHCCCHHEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHH
AMNEFAG
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2575703 [H]