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The map label for this gene is umuC [H]

Identifier: 160875396

GI number: 160875396

Start: 2706012

End: 2706782

Strand: Direct

Name: umuC [H]

Synonym: Sbal195_2284

Alternate gene names: 160875396

Gene position: 2706012-2706782 (Clockwise)

Preceding gene: 160875393

Following gene: 160875397

Centisome position: 50.61

GC content: 45.65

Gene sequence:

>771_bases
GTGTGTGTTATCGATAATGAACAAGACCGAATTTCAATTTTACAATCAATGAATGTGAATGATGTCTGGGGCATTGGGCG
CAGGATAAGCAAAAAACTTGAATTGATGAACGTCAAGACCGCCTATGACTTAGCCAAAATCCCTGCAGGTTTAGCGCGAA
AGCAATTTAGTATTGAAATAGAACGCACTGTGCGTGAACTCAATGGGCAAGCGTGCAAAGTGTGGGACGAGGCGAGGGCG
GATAAGAAGCAAATATTCTCAACTCGTAGTGTGGGTGAGCGTATTACTGAGTATGAGGATTTACTGCAAGCCTTAAGTAA
ACATGTGGCGATTGCTGCAGCGAAAGCGCGTAAGCAAGGCTCAAGCTGTAAAACCATGTTGTTGTTTGCTAGCAATTCTC
CCTACGATGAACGCCCAACAGGCTTTAAGACCTTAGTGCACTTTGCTTGTGCCACCGATTGCAGCATTGAACTCACTCAG
GGTATGACACAAGCAGCATCTCAACTTTTCCGCGCAGGCGTACGTTATTATAAAATCGGTGTCGGCCTGATTGATTTGGT
CAGCACCCAGCATGGCCAGTTAGATTTATTCAATGTTTCAAAAGCTAAACCCGCGTTAATGAAGACTCTTGATGGCATCA
ATCAACGTTATGGCACAGACACCTTATTCATTGCCGCCCAAGGTATCGAGCAAAAATGGGCCATGCGCCGCGACCTACTC
ACACCGCAATACACGACTAAGTGGAAATGTCTGCCAGAGATAAAGTGCTGA

Upstream 100 bases:

>100_bases
GTCGATCTCATGTGTTCACCTAAAGTCATCTACGAGGCAATAATATCACCTCTATTTAGGTGGCCAAAATTAGTGTGCCA
CTACACCTGGCTATCAGGGT

Downstream 100 bases:

>100_bases
TATCCGGCAGTAGATGGAGTAACACGTTTATGCCTCAAAGCGTGTCAGTATTGCTTAGACCCAATTTTTAGTCATACTAC
AGAGTGGCTACTGTAACTGT

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MCVIDNEQDRISILQSMNVNDVWGIGRRISKKLELMNVKTAYDLAKIPAGLARKQFSIEIERTVRELNGQACKVWDEARA
DKKQIFSTRSVGERITEYEDLLQALSKHVAIAAAKARKQGSSCKTMLLFASNSPYDERPTGFKTLVHFACATDCSIELTQ
GMTQAASQLFRAGVRYYKIGVGLIDLVSTQHGQLDLFNVSKAKPALMKTLDGINQRYGTDTLFIAAQGIEQKWAMRRDLL
TPQYTTKWKCLPEIKC

Sequences:

>Translated_256_residues
MCVIDNEQDRISILQSMNVNDVWGIGRRISKKLELMNVKTAYDLAKIPAGLARKQFSIEIERTVRELNGQACKVWDEARA
DKKQIFSTRSVGERITEYEDLLQALSKHVAIAAAKARKQGSSCKTMLLFASNSPYDERPTGFKTLVHFACATDCSIELTQ
GMTQAASQLFRAGVRYYKIGVGLIDLVSTQHGQLDLFNVSKAKPALMKTLDGINQRYGTDTLFIAAQGIEQKWAMRRDLL
TPQYTTKWKCLPEIKC
>Mature_256_residues
MCVIDNEQDRISILQSMNVNDVWGIGRRISKKLELMNVKTAYDLAKIPAGLARKQFSIEIERTVRELNGQACKVWDEARA
DKKQIFSTRSVGERITEYEDLLQALSKHVAIAAAKARKQGSSCKTMLLFASNSPYDERPTGFKTLVHFACATDCSIELTQ
GMTQAASQLFRAGVRYYKIGVGLIDLVSTQHGQLDLFNVSKAKPALMKTLDGINQRYGTDTLFIAAQGIEQKWAMRRDLL
TPQYTTKWKCLPEIKC

Specific function: Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template [H]

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Escherichia coli, GI1787432, Length=257, Percent_Identity=38.1322957198444, Blast_Score=179, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: NA

Molecular weight: Translated: 28789; Mature: 28789

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCVIDNEQDRISILQSMNVNDVWGIGRRISKKLELMNVKTAYDLAKIPAGLARKQFSIEI
CCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ERTVRELNGQACKVWDEARADKKQIFSTRSVGERITEYEDLLQALSKHVAIAAAKARKQG
HHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SSCKTMLLFASNSPYDERPTGFKTLVHFACATDCSIELTQGMTQAASQLFRAGVRYYKIG
CCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHEEHH
VGLIDLVSTQHGQLDLFNVSKAKPALMKTLDGINQRYGTDTLFIAAQGIEQKWAMRRDLL
HHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHCC
TPQYTTKWKCLPEIKC
CCCCCCCCCCCCCCCC
>Mature Secondary Structure
MCVIDNEQDRISILQSMNVNDVWGIGRRISKKLELMNVKTAYDLAKIPAGLARKQFSIEI
CCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ERTVRELNGQACKVWDEARADKKQIFSTRSVGERITEYEDLLQALSKHVAIAAAKARKQG
HHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SSCKTMLLFASNSPYDERPTGFKTLVHFACATDCSIELTQGMTQAASQLFRAGVRYYKIG
CCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHEEHH
VGLIDLVSTQHGQLDLFNVSKAKPALMKTLDGINQRYGTDTLFIAAQGIEQKWAMRRDLL
HHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHCC
TPQYTTKWKCLPEIKC
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2989817; 2989816; 8905232; 9278503; 1320188 [H]