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The map label for this gene is nadA [H]

Identifier: 160875315

GI number: 160875315

Start: 2615712

End: 2616794

Strand: Direct

Name: nadA [H]

Synonym: Sbal195_2202

Alternate gene names: 160875315

Gene position: 2615712-2616794 (Clockwise)

Preceding gene: 160875314

Following gene: 160875318

Centisome position: 48.92

GC content: 49.49

Gene sequence:

>1083_bases
ATGAGTCAGTTTGCCCCCAGCCCATTTGCTCCAACAATAGAAACCATTGATTACCCGTTTCCGCCTAAGCCAGTTCCTTT
GTCCGATGCGCAAAAAGCCGATTACAAGACGCGTATCAAACAACTGCTCATTGAAAAAGATGCCGTTCTGGTTGCCCACT
ATTATACCGATCCTGAAATCCAAGCCCTTGCCGAAGAAACCGGCGGCTGCGTTTCAGACTCCTTAGAAATGGCGCGCTTT
GGCCGCGATCACCCAGCAAAAACCTTAATCGTTGCTGGGGTCAAGTTTATGGGCGAAACCGCCAAGATTTTGAGCCCAGA
AAAAACCATTTTAATGCCGACCTTAGAAGCCACTTGTTCATTGGACTTAGGTTGTCCAATCGATAAGTTCAGTGCTTTCT
GCGACGCGCACCCAGATCATACTGTGGTGGTTTACGCCAATACTTCGGCAGCCGTTAAAGCGCGCGCCGACTGGGTGGTG
ACCTCTAGTATTGCCCTCGAAATCGTTGAGCACTTAGACAGCGAAAGTAAAAAGATCATTTGGGGACCAGACCGTCATTT
AGGCAGTTATATTGCTAAACAGACGGGCGCCGAAATGTTGATGTGGCAGGGCGATTGTATCGTTCACGACGAGTTTAAAT
CGAACGCGCTGCGCGATATGAAAAGCGTTTACCCAGATGCAGCTATCCTTGTGCATCCTGAGTCACCAGCCAATGTGGTG
GCGATGGCCGATGCCGTTGGCTCGACCAGTCAATTGATCAAAGCGGCGCAGACTATGCCTAATGAGCGTTTTATTGTGGC
AACCGATCGCGGCATCTTCTATAAAATGCAGCAGGCGGCGCCAGGTAAAATCTTAATCGAAGCGCCAACAGGCGGAAATG
GCGCAACCTGTAAGAGTTGCGCTCACTGTCCTTGGATGGCGATGAACGGTCTACAGGCGATTGAAGCATCACTCGCCGAC
AGCGATAAAACCACCCATGAGATTTTTGTGGATGAAGACTTAAGAGTTAAAGCGCTGATCCCGCTGACGCGCATGTTGGA
TTTTGCTCAGACACTGAATATGAAAGTGAAGGGTAATGCCTAA

Upstream 100 bases:

>100_bases
GCTTTAGAGCGTCCTTTTTTATTTGCTTTGCACAAATGGGTTAATCTTTTGATCCCGATTACGTATAATTCCCGGACGTA
GTTATCCTGATGGATGTGTT

Downstream 100 bases:

>100_bases
ACATGGCTAAGTCCCTTCTTTAGCTGTTCTCCAGTGTCATAAAAATCCCCGCCATAGAGTGGGGATTTTTTATGGCTGGA
ATTTAAGGCAATAAAAAGCC

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MSQFAPSPFAPTIETIDYPFPPKPVPLSDAQKADYKTRIKQLLIEKDAVLVAHYYTDPEIQALAEETGGCVSDSLEMARF
GRDHPAKTLIVAGVKFMGETAKILSPEKTILMPTLEATCSLDLGCPIDKFSAFCDAHPDHTVVVYANTSAAVKARADWVV
TSSIALEIVEHLDSESKKIIWGPDRHLGSYIAKQTGAEMLMWQGDCIVHDEFKSNALRDMKSVYPDAAILVHPESPANVV
AMADAVGSTSQLIKAAQTMPNERFIVATDRGIFYKMQQAAPGKILIEAPTGGNGATCKSCAHCPWMAMNGLQAIEASLAD
SDKTTHEIFVDEDLRVKALIPLTRMLDFAQTLNMKVKGNA

Sequences:

>Translated_360_residues
MSQFAPSPFAPTIETIDYPFPPKPVPLSDAQKADYKTRIKQLLIEKDAVLVAHYYTDPEIQALAEETGGCVSDSLEMARF
GRDHPAKTLIVAGVKFMGETAKILSPEKTILMPTLEATCSLDLGCPIDKFSAFCDAHPDHTVVVYANTSAAVKARADWVV
TSSIALEIVEHLDSESKKIIWGPDRHLGSYIAKQTGAEMLMWQGDCIVHDEFKSNALRDMKSVYPDAAILVHPESPANVV
AMADAVGSTSQLIKAAQTMPNERFIVATDRGIFYKMQQAAPGKILIEAPTGGNGATCKSCAHCPWMAMNGLQAIEASLAD
SDKTTHEIFVDEDLRVKALIPLTRMLDFAQTLNMKVKGNA
>Mature_359_residues
SQFAPSPFAPTIETIDYPFPPKPVPLSDAQKADYKTRIKQLLIEKDAVLVAHYYTDPEIQALAEETGGCVSDSLEMARFG
RDHPAKTLIVAGVKFMGETAKILSPEKTILMPTLEATCSLDLGCPIDKFSAFCDAHPDHTVVVYANTSAAVKARADWVVT
SSIALEIVEHLDSESKKIIWGPDRHLGSYIAKQTGAEMLMWQGDCIVHDEFKSNALRDMKSVYPDAAILVHPESPANVVA
MADAVGSTSQLIKAAQTMPNERFIVATDRGIFYKMQQAAPGKILIEAPTGGNGATCKSCAHCPWMAMNGLQAIEASLADS
DKTTHEIFVDEDLRVKALIPLTRMLDFAQTLNMKVKGNA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=340, Percent_Identity=73.2352941176471, Blast_Score=533, Evalue=1e-153,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 39167; Mature: 39036

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQFAPSPFAPTIETIDYPFPPKPVPLSDAQKADYKTRIKQLLIEKDAVLVAHYYTDPEI
CCCCCCCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCHHH
QALAEETGGCVSDSLEMARFGRDHPAKTLIVAGVKFMGETAKILSPEKTILMPTLEATCS
HHHHHHHCCCHHHHHHHHHCCCCCCCCEEEEEHHHHHCCHHHHCCCCCEEEEEECHHHEE
LDLGCPIDKFSAFCDAHPDHTVVVYANTSAAVKARADWVVTSSIALEIVEHLDSESKKII
ECCCCCHHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEEHHHHHHHHHHCCCCCCEEE
WGPDRHLGSYIAKQTGAEMLMWQGDCIVHDEFKSNALRDMKSVYPDAAILVHPESPANVV
ECCCHHHHHHHHHHCCCCEEEECCCEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCCEE
AMADAVGSTSQLIKAAQTMPNERFIVATDRGIFYKMQQAAPGKILIEAPTGGNGATCKSC
EEEHHCCCHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCCCEEEEECCCCCCCCCCHHH
AHCPWMAMNGLQAIEASLADSDKTTHEIFVDEDLRVKALIPLTRMLDFAQTLNMKVKGNA
CCCCHHHHCCHHHHHHHHCCCCCCCEEEEECCCCEEEEEHHHHHHHHHHHHCCEEEECCC
>Mature Secondary Structure 
SQFAPSPFAPTIETIDYPFPPKPVPLSDAQKADYKTRIKQLLIEKDAVLVAHYYTDPEI
CCCCCCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCHHH
QALAEETGGCVSDSLEMARFGRDHPAKTLIVAGVKFMGETAKILSPEKTILMPTLEATCS
HHHHHHHCCCHHHHHHHHHCCCCCCCCEEEEEHHHHHCCHHHHCCCCCEEEEEECHHHEE
LDLGCPIDKFSAFCDAHPDHTVVVYANTSAAVKARADWVVTSSIALEIVEHLDSESKKII
ECCCCCHHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEEHHHHHHHHHHCCCCCCEEE
WGPDRHLGSYIAKQTGAEMLMWQGDCIVHDEFKSNALRDMKSVYPDAAILVHPESPANVV
ECCCHHHHHHHHHHCCCCEEEECCCEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCCEE
AMADAVGSTSQLIKAAQTMPNERFIVATDRGIFYKMQQAAPGKILIEAPTGGNGATCKSC
EEEHHCCCHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCCCEEEEECCCCCCCCCCHHH
AHCPWMAMNGLQAIEASLADSDKTTHEIFVDEDLRVKALIPLTRMLDFAQTLNMKVKGNA
CCCCHHHHCCHHHHHHHHCCCCCCCEEEEECCCCEEEEEHHHHHHHHHHHHCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]