Click here to switch to the map view.

The map label for this gene is pgl [H]

Identifier: 160875289

GI number: 160875289

Start: 2587070

End: 2587768

Strand: Direct

Name: pgl [H]

Synonym: Sbal195_2176

Alternate gene names: 160875289

Gene position: 2587070-2587768 (Clockwise)

Preceding gene: 160875288

Following gene: 160875290

Centisome position: 48.38

GC content: 49.36

Gene sequence:

>699_bases
ATGATTAAAGAAACCGTATTCAAATCTTTCGATACGCCAAGTGCGTTAGAACAGCAACTGGCCAGCAAGATTGCGAGCCA
GTTACAGGAAGCCGTCGATGCCCGCGGAAAAGCGAGCCTAGTGGTTTCCGGTGGTTCGACGCCGCTTAAGTTATTTCAAC
TATTGAGCATGAAGTCCATCGATTGGAGTGATGTTTATATCACTCTCGCCGATGAGCGCTGGGTTGAAGCCGACGCCGAT
GCTTCTAATGAACGTCTAGTGCGTGAACATTTATTACAAAACCGCGCGTCGAATGCCAAATTCCGCGGTTTAAAAAACAT
GTTTTCGACCGCAGAAGCGGGCGCCGATATGGCCGCCGAGTCTTTGTCTAATTTCCCGCGTCCTTTTGATGTGGTGGTAT
TAGGCATGGGTAACGATGGTCATACATGTTCTTGGTTTCCCTGTAGCGCTGAGCTTGAAAATGCGCTCACAACCCAAGCC
CTGTGCGTGGCGACTAACCCCACCACAGCGCCCCACGGCAGAATAACGCTCTCTAAGAGTGCGATTCTGAACAGCAGACA
AATTTATCTGCACTTGGTCGGGGAACAGAAATTATCCGTATATCGTCAAGCGTTAGAAAGTGATGATGTCCATGCTATGC
CTATCAGAGCCGTATTAGCGCAGCGTAAAACGCCCGTTGATGTGTTCTGGAGCGCTTAA

Upstream 100 bases:

>100_bases
CGAAAAACCAAAACCTTATCCTGCGGGTACTTGGGGTCCAGTTGCGTCAGTTGCTTTGATCACCAAAGATGGCCGTTCGT
GGGACGAGTAGGAGACTTTG

Downstream 100 bases:

>100_bases
GGAGTCAAGATGCACTCAGTAGTTCAAGCTGTTACCGACAGAATTATTGCCCGTAGCAAAGCGTCACGTGAAGGTTATCT
CGCCGCATTGAATGATGCCC

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MIKETVFKSFDTPSALEQQLASKIASQLQEAVDARGKASLVVSGGSTPLKLFQLLSMKSIDWSDVYITLADERWVEADAD
ASNERLVREHLLQNRASNAKFRGLKNMFSTAEAGADMAAESLSNFPRPFDVVVLGMGNDGHTCSWFPCSAELENALTTQA
LCVATNPTTAPHGRITLSKSAILNSRQIYLHLVGEQKLSVYRQALESDDVHAMPIRAVLAQRKTPVDVFWSA

Sequences:

>Translated_232_residues
MIKETVFKSFDTPSALEQQLASKIASQLQEAVDARGKASLVVSGGSTPLKLFQLLSMKSIDWSDVYITLADERWVEADAD
ASNERLVREHLLQNRASNAKFRGLKNMFSTAEAGADMAAESLSNFPRPFDVVVLGMGNDGHTCSWFPCSAELENALTTQA
LCVATNPTTAPHGRITLSKSAILNSRQIYLHLVGEQKLSVYRQALESDDVHAMPIRAVLAQRKTPVDVFWSA
>Mature_232_residues
MIKETVFKSFDTPSALEQQLASKIASQLQEAVDARGKASLVVSGGSTPLKLFQLLSMKSIDWSDVYITLADERWVEADAD
ASNERLVREHLLQNRASNAKFRGLKNMFSTAEAGADMAAESLSNFPRPFDVVVLGMGNDGHTCSWFPCSAELENALTTQA
LCVATNPTTAPHGRITLSKSAILNSRQIYLHLVGEQKLSVYRQALESDDVHAMPIRAVLAQRKTPVDVFWSA

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI52145310, Length=201, Percent_Identity=31.3432835820896, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI115533060, Length=202, Percent_Identity=29.7029702970297, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI115533058, Length=202, Percent_Identity=29.7029702970297, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6321957, Length=209, Percent_Identity=28.7081339712919, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 25426; Mature: 25426

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKETVFKSFDTPSALEQQLASKIASQLQEAVDARGKASLVVSGGSTPLKLFQLLSMKSI
CCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCC
DWSDVYITLADERWVEADADASNERLVREHLLQNRASNAKFRGLKNMFSTAEAGADMAAE
CCCEEEEEEECCCEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
SLSNFPRPFDVVVLGMGNDGHTCSWFPCSAELENALTTQALCVATNPTTAPHGRITLSKS
HHHCCCCCEEEEEEEECCCCCEEEEECCCHHHHHHHHHHEEEEECCCCCCCCCEEEEEHH
AILNSRQIYLHLVGEQKLSVYRQALESDDVHAMPIRAVLAQRKTPVDVFWSA
HHHCCCEEEEEEECCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEECC
>Mature Secondary Structure
MIKETVFKSFDTPSALEQQLASKIASQLQEAVDARGKASLVVSGGSTPLKLFQLLSMKSI
CCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCC
DWSDVYITLADERWVEADADASNERLVREHLLQNRASNAKFRGLKNMFSTAEAGADMAAE
CCCEEEEEEECCCEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
SLSNFPRPFDVVVLGMGNDGHTCSWFPCSAELENALTTQALCVATNPTTAPHGRITLSKS
HHHCCCCCEEEEEEEECCCCCEEEEECCCHHHHHHHHHHEEEEECCCCCCCCCEEEEEHH
AILNSRQIYLHLVGEQKLSVYRQALESDDVHAMPIRAVLAQRKTPVDVFWSA
HHHCCCEEEEEEECCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]