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The map label for this gene is cysM [C]

Identifier: 160875276

GI number: 160875276

Start: 2569857

End: 2570978

Strand: Reverse

Name: cysM [C]

Synonym: Sbal195_2163

Alternate gene names: 160875276

Gene position: 2570978-2569857 (Counterclockwise)

Preceding gene: 160875280

Following gene: 160875274

Centisome position: 48.08

GC content: 49.55

Gene sequence:

>1122_bases
ATGATATCTAACACAATTCAACCGCCAGTGGACTCACACAGCGCTCACAGACTCTGCCCAACGTGGGAAGCCCATGCGAT
AGGCAAGATTGAAGCGGATTTTCAGCGCAGCGCCGATACCCATTTGATTAAACTTGAATTACCTATGCTCGATGGCATAG
ATATTTATCTTAAAGATGAAAGTACCCACCCGACAGGCAGCTTAAAGCATCGCCTCGCCCGCTCACTCTTCCTCTATGCC
CTGTGTAACGGCTGGATTAAGCAAGGCACACCCATTATCGAATCCTCATCTGGCAGCACGGCGATTTCTGAAGCCTATTT
TGCCCGCTTACTCGGTTTACCTTTTATTGCCGTGATGCCTAAAAGTACGGCTAAAAAGAAGATTGAACAGATCACTTTCT
ATGGCGGCCAATGTCATTTTGTCGATCATTCCAGTGAGATTTACGCCGAATCGGCACGCCTCGCCGCAGAGCTTGGCGGC
CATTATATGGATCAATTCACCTACGCCGAGCGCGCGACCGACTGGCGCGGTAATAATAATATCGCCAATTCGATTTTCAA
TCAGATGGAGCGCGAGCCACACACTATCCCGCGTTGGATAGTGATGAGTCCGGGCACAGGCGGCACATCGGCGACCATAG
GCCGTTACATTCGCTATCAAAGGTTGGCGACCCAGCTTTGCGTGGTCGATCCGCAAAACTCGGTGTTTTTTGATTTCTAT
CAGAGCGGCGATGCCAGCTTAACCTGTTGCAATGGCAGTAAGATTGAAGGCATAGGTCGACCAAGAGTTGAGCCATCCTT
TATTCCTGGCGTTGTCGATACTATGCTGCAAATCCCCGACGCAGCTTCCGTAGCGACAATTCATTGGTTAGAACAACTGA
TTGGCCGTAAAACCGGCGCATCGACGGGCACTAACCTGTACGGTGCATTGCAACTTGCCGTACAAATGCAAGCGCGCGGA
GAGCAAGGCTCAATCGTGACCCTAATTTGTGATTCGGGTGAGCGTTATCTCGATACTTATTACGATGCTGATTGGATTGC
GGCTAATATTGGTGATATTGCCCCCTATCAGCGCCAACTTGCGGCATTCAATCATTTTGGTCAACTAAGCGAGCTTGATT
AA

Upstream 100 bases:

>100_bases
GCTAATGCCCCCAAGCGAGTAACGCCAAGCAGATCCAATAAAACCGCTTTGCCCGTCCCTGTGATATGCTCTAAAAATGA
TCCCTTTCGAAGTGACTATG

Downstream 100 bases:

>100_bases
CCGACTCGATTAAATCCCTTGAGTTGACGGTTTTAAAGTCCACCGCTAAACGTCAGCCATAAAAAACGCCCCACAGTTGT
GAGGCGTTTTTTATCGTTGG

Product: pyridoxal-5'-phosphate-dependent protein subunit beta

Products: NA

Alternate protein names: O-acetylserine (Thiol)-lyase; O-acetylserine sulfhydrylase; CSase [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MISNTIQPPVDSHSAHRLCPTWEAHAIGKIEADFQRSADTHLIKLELPMLDGIDIYLKDESTHPTGSLKHRLARSLFLYA
LCNGWIKQGTPIIESSSGSTAISEAYFARLLGLPFIAVMPKSTAKKKIEQITFYGGQCHFVDHSSEIYAESARLAAELGG
HYMDQFTYAERATDWRGNNNIANSIFNQMEREPHTIPRWIVMSPGTGGTSATIGRYIRYQRLATQLCVVDPQNSVFFDFY
QSGDASLTCCNGSKIEGIGRPRVEPSFIPGVVDTMLQIPDAASVATIHWLEQLIGRKTGASTGTNLYGALQLAVQMQARG
EQGSIVTLICDSGERYLDTYYDADWIAANIGDIAPYQRQLAAFNHFGQLSELD

Sequences:

>Translated_373_residues
MISNTIQPPVDSHSAHRLCPTWEAHAIGKIEADFQRSADTHLIKLELPMLDGIDIYLKDESTHPTGSLKHRLARSLFLYA
LCNGWIKQGTPIIESSSGSTAISEAYFARLLGLPFIAVMPKSTAKKKIEQITFYGGQCHFVDHSSEIYAESARLAAELGG
HYMDQFTYAERATDWRGNNNIANSIFNQMEREPHTIPRWIVMSPGTGGTSATIGRYIRYQRLATQLCVVDPQNSVFFDFY
QSGDASLTCCNGSKIEGIGRPRVEPSFIPGVVDTMLQIPDAASVATIHWLEQLIGRKTGASTGTNLYGALQLAVQMQARG
EQGSIVTLICDSGERYLDTYYDADWIAANIGDIAPYQRQLAAFNHFGQLSELD
>Mature_373_residues
MISNTIQPPVDSHSAHRLCPTWEAHAIGKIEADFQRSADTHLIKLELPMLDGIDIYLKDESTHPTGSLKHRLARSLFLYA
LCNGWIKQGTPIIESSSGSTAISEAYFARLLGLPFIAVMPKSTAKKKIEQITFYGGQCHFVDHSSEIYAESARLAAELGG
HYMDQFTYAERATDWRGNNNIANSIFNQMEREPHTIPRWIVMSPGTGGTSATIGRYIRYQRLATQLCVVDPQNSVFFDFY
QSGDASLTCCNGSKIEGIGRPRVEPSFIPGVVDTMLQIPDAASVATIHWLEQLIGRKTGASTGTNLYGALQLAVQMQARG
EQGSIVTLICDSGERYLDTYYDADWIAANIGDIAPYQRQLAAFNHFGQLSELD

Specific function: As it is highly similar to bacterial and plant cysteine synthases, it is possible that it catalyzes a related reaction [H]

COG id: COG0031

COG function: function code E; Cysteine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cysteine synthase/cystathionine beta- synthase family [H]

Homologues:

Organism=Homo sapiens, GI295821202, Length=300, Percent_Identity=24, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI295821200, Length=300, Percent_Identity=24, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI4557415, Length=300, Percent_Identity=24, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI2367138, Length=317, Percent_Identity=29.6529968454259, Blast_Score=90, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71996324, Length=350, Percent_Identity=33.1428571428571, Blast_Score=167, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI17539800, Length=355, Percent_Identity=31.5492957746479, Blast_Score=154, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI17539640, Length=355, Percent_Identity=29.2957746478873, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI32566674, Length=302, Percent_Identity=27.1523178807947, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562970, Length=311, Percent_Identity=26.6881028938907, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI115535073, Length=294, Percent_Identity=25.8503401360544, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17534315, Length=329, Percent_Identity=27.0516717325228, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6321449, Length=330, Percent_Identity=24.2424242424242, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24643623, Length=324, Percent_Identity=26.8518518518519, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI20129101, Length=324, Percent_Identity=26.8518518518519, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001216
- InterPro:   IPR001926 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =2.5.1.47 [H]

Molecular weight: Translated: 41232; Mature: 41232

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISNTIQPPVDSHSAHRLCPTWEAHAIGKIEADFQRSADTHLIKLELPMLDGIDIYLKDE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCEEEEEEECCCCCEEEEEECC
STHPTGSLKHRLARSLFLYALCNGWIKQGTPIIESSSGSTAISEAYFARLLGLPFIAVMP
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHCCCEEEECC
KSTAKKKIEQITFYGGQCHFVDHSSEIYAESARLAAELGGHYMDQFTYAERATDWRGNNN
CHHHHHHHHHEEEECCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCH
IANSIFNQMEREPHTIPRWIVMSPGTGGTSATIGRYIRYQRLATQLCVVDPQNSVFFDFY
HHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHEEEECCCCCEEEEEE
QSGDASLTCCNGSKIEGIGRPRVEPSFIPGVVDTMLQIPDAASVATIHWLEQLIGRKTGA
CCCCCEEEEECCCEECCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCC
STGTNLYGALQLAVQMQARGEQGSIVTLICDSGERYLDTYYDADWIAANIGDIAPYQRQL
CCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHCCCCCEEECCCCCCHHHHHH
AAFNHFGQLSELD
HHHHHCCCCCCCC
>Mature Secondary Structure
MISNTIQPPVDSHSAHRLCPTWEAHAIGKIEADFQRSADTHLIKLELPMLDGIDIYLKDE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCEEEEEEECCCCCEEEEEECC
STHPTGSLKHRLARSLFLYALCNGWIKQGTPIIESSSGSTAISEAYFARLLGLPFIAVMP
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHCCCEEEECC
KSTAKKKIEQITFYGGQCHFVDHSSEIYAESARLAAELGGHYMDQFTYAERATDWRGNNN
CHHHHHHHHHEEEECCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCH
IANSIFNQMEREPHTIPRWIVMSPGTGGTSATIGRYIRYQRLATQLCVVDPQNSVFFDFY
HHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHEEEECCCCCEEEEEE
QSGDASLTCCNGSKIEGIGRPRVEPSFIPGVVDTMLQIPDAASVATIHWLEQLIGRKTGA
CCCCCEEEEECCCEECCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCC
STGTNLYGALQLAVQMQARGEQGSIVTLICDSGERYLDTYYDADWIAANIGDIAPYQRQL
CCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHCCCCCEEECCCCCCHHHHHH
AAFNHFGQLSELD
HHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]