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The map label for this gene is csrD [H]

Identifier: 160875226

GI number: 160875226

Start: 2522727

End: 2524631

Strand: Reverse

Name: csrD [H]

Synonym: Sbal195_2113

Alternate gene names: 160875226

Gene position: 2524631-2522727 (Counterclockwise)

Preceding gene: 160875227

Following gene: 160875225

Centisome position: 47.21

GC content: 43.57

Gene sequence:

>1905_bases
ATGGCCATGTCAAAATCATATCCAATTTTTTTACTGCTTATTTTCTTAGGTCTCTTTGCTTGGGTGTATCAAAGCGAAAA
CAGCCAATTGCAAGTCCAACAGCAGCAAGAACTCGATAGCTTTAAATCTAGCTTAAGCCGCTACCAACAATGGCAGGGTA
ACGGTGTAGAACTCTTTAAAAAACTTTCTGAAAACTACTCATTCCAGTTCTTCCAATATATTGATGATACCGACGGCCAA
CTGAGCCATACCGAAGGAAGCTTAGACAGTCAACATCCCCATCCTTTAGCGAGTTTATTTTCCATCGAACTCAGCCACAC
ACAAAAATTGGCATCGGGTCGTTTACAGGTCAAGCTCAGTGCAAACCAAGCCATTGATACTGCAATTAGTAACACTCAAA
AACTCGGTGTCATGTTGCTAGTGACTTACCTTATTTTGCTATTAGTGTTTATTCTATTAATGTCGAAACTCAGAGCTGCG
GTACGTTATGCTGCTGATTATATTTCAAAAATACCCGAGTTAGGCTTTTCTGCCGTCGCAGCATCGAAACTCACTGGCGA
GCTCACCCCTATTGGTATCTCACTCGAAGAATGTCGCCTGCAACTTAAAGCCCAAATCGATAAGCTCAATCAAGAAAATG
AAAAACTGCATAAAGCAGCCTATCAAGACGCCGTCACAGGTTTTGGTAGTCGCCAACGTTTCACCCAAAAATTAGAAACC
ATTAGTCATCCCGATATTCCTCAACTTGGGCTGATGGCAATGGTTAAAGCGACTGAGCTGACCCTCATTAACCAAAAACA
AGGCCGTTCAGCGGGTGATGATTATCTCGCAAGAGTCGCAAATTGCATTCGTAAAGCCTGTAGCAAATATCCAGATGCTG
AGTGTTTTAGGGTATCAAGTGCCGATTTTGCAGTGTTTATTCCCGATGTCATGCTAAAAGATGCACCGAAATTTTTGGAC
CAATTAAAAATTTACCTCGATGAATATCTGCAAATGACAAAAGCAGAATCCGTCGCCCATATTGGCTTAGTTCCTTATAG
TCAAGGGATTGACCCTGTAAATTTACTGACTATAGCCGATACCGCGGTCAGCATAGCTCAGACCCTTGGCCCCAATAGCT
ATCACATCCAAGAGAAACTCAATGGGGATGAACAGTTTGGTGACGATCGTTGGAAGATGGCAATCCATGATTTAGTGACA
CGCCAAGCATTGAAATTCTACCAGCAGCCTATTCAGCCGTGTCGTACCGATGTAGAGGTTTACCGTGAGTTGTTGGCGCG
CTTTTACAATAGCGAAGGCAAGTTCTTACCTACCACCACTGTGATTGCTATGGCTGAACGTCACGGTATGAGTTCGGAAT
TGGATAAACTGGTTGTGATCAGTGCATTAAAGATACTTAAGGAAAACCCGACTATTTCCGGTAACTTTGGTATCAATATC
AGCGCATTTTCAGCCCATCAAGACATGTTTGTCGCTTGGCTAAAAGACATACTAGGTAAGCAAAAATACATAGCATCGCG
TTTAGTCTTTGAGATCAACGAGTCCGGCATGCAGTCTAACTTAGGGGCGAGTTATAAGTTTGTCCGCGAAGTGCACAGTG
TCGGTTCGCGAGTGTCGATTGAGCGTTTTGGCATGAGCTTTACCTCCTTCAAATTCTTCAGCGAAGTGCGCCCCGACTAC
ATTAAGCTCGATGGCAGCTACACGTCTAACATCGATGAAGACAGCAATAATAAGTTCTTTGTGCGTATGATGGTGGATGT
CGCCAGACGAATTGGCATTCGGGTCATCGCAACCAGTGTCGAACGCCAAGAAGAAAAATTAACCCTCGAAAAACTCTTAG
TCGATGGATTGCAGGGCTATTACATCGCACAACCCCAAGCCATGGCCATTACAGATCAGATTTAA

Upstream 100 bases:

>100_bases
TGAACAAATTTATGAGTATCTTCACACAGATAGCGGTTTTTAAGTATTCTTGGCTTAAACTTATCTTGTTCGAACTCACC
AAAATCTAGAGCGGATTTTT

Downstream 100 bases:

>100_bases
TACTTTAACGGGTTAATTCATCGCCAAAATTTACAGTAAAGATGGTTAACCCTGCATTCTATATGTTGTTTATGCATACG
GAAAAGTCGATAATACGGCC

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: Regulator of CsrB and CsrC decay CsrD [H]

Number of amino acids: Translated: 634; Mature: 633

Protein sequence:

>634_residues
MAMSKSYPIFLLLIFLGLFAWVYQSENSQLQVQQQQELDSFKSSLSRYQQWQGNGVELFKKLSENYSFQFFQYIDDTDGQ
LSHTEGSLDSQHPHPLASLFSIELSHTQKLASGRLQVKLSANQAIDTAISNTQKLGVMLLVTYLILLLVFILLMSKLRAA
VRYAADYISKIPELGFSAVAASKLTGELTPIGISLEECRLQLKAQIDKLNQENEKLHKAAYQDAVTGFGSRQRFTQKLET
ISHPDIPQLGLMAMVKATELTLINQKQGRSAGDDYLARVANCIRKACSKYPDAECFRVSSADFAVFIPDVMLKDAPKFLD
QLKIYLDEYLQMTKAESVAHIGLVPYSQGIDPVNLLTIADTAVSIAQTLGPNSYHIQEKLNGDEQFGDDRWKMAIHDLVT
RQALKFYQQPIQPCRTDVEVYRELLARFYNSEGKFLPTTTVIAMAERHGMSSELDKLVVISALKILKENPTISGNFGINI
SAFSAHQDMFVAWLKDILGKQKYIASRLVFEINESGMQSNLGASYKFVREVHSVGSRVSIERFGMSFTSFKFFSEVRPDY
IKLDGSYTSNIDEDSNNKFFVRMMVDVARRIGIRVIATSVERQEEKLTLEKLLVDGLQGYYIAQPQAMAITDQI

Sequences:

>Translated_634_residues
MAMSKSYPIFLLLIFLGLFAWVYQSENSQLQVQQQQELDSFKSSLSRYQQWQGNGVELFKKLSENYSFQFFQYIDDTDGQ
LSHTEGSLDSQHPHPLASLFSIELSHTQKLASGRLQVKLSANQAIDTAISNTQKLGVMLLVTYLILLLVFILLMSKLRAA
VRYAADYISKIPELGFSAVAASKLTGELTPIGISLEECRLQLKAQIDKLNQENEKLHKAAYQDAVTGFGSRQRFTQKLET
ISHPDIPQLGLMAMVKATELTLINQKQGRSAGDDYLARVANCIRKACSKYPDAECFRVSSADFAVFIPDVMLKDAPKFLD
QLKIYLDEYLQMTKAESVAHIGLVPYSQGIDPVNLLTIADTAVSIAQTLGPNSYHIQEKLNGDEQFGDDRWKMAIHDLVT
RQALKFYQQPIQPCRTDVEVYRELLARFYNSEGKFLPTTTVIAMAERHGMSSELDKLVVISALKILKENPTISGNFGINI
SAFSAHQDMFVAWLKDILGKQKYIASRLVFEINESGMQSNLGASYKFVREVHSVGSRVSIERFGMSFTSFKFFSEVRPDY
IKLDGSYTSNIDEDSNNKFFVRMMVDVARRIGIRVIATSVERQEEKLTLEKLLVDGLQGYYIAQPQAMAITDQI
>Mature_633_residues
AMSKSYPIFLLLIFLGLFAWVYQSENSQLQVQQQQELDSFKSSLSRYQQWQGNGVELFKKLSENYSFQFFQYIDDTDGQL
SHTEGSLDSQHPHPLASLFSIELSHTQKLASGRLQVKLSANQAIDTAISNTQKLGVMLLVTYLILLLVFILLMSKLRAAV
RYAADYISKIPELGFSAVAASKLTGELTPIGISLEECRLQLKAQIDKLNQENEKLHKAAYQDAVTGFGSRQRFTQKLETI
SHPDIPQLGLMAMVKATELTLINQKQGRSAGDDYLARVANCIRKACSKYPDAECFRVSSADFAVFIPDVMLKDAPKFLDQ
LKIYLDEYLQMTKAESVAHIGLVPYSQGIDPVNLLTIADTAVSIAQTLGPNSYHIQEKLNGDEQFGDDRWKMAIHDLVTR
QALKFYQQPIQPCRTDVEVYRELLARFYNSEGKFLPTTTVIAMAERHGMSSELDKLVVISALKILKENPTISGNFGINIS
AFSAHQDMFVAWLKDILGKQKYIASRLVFEINESGMQSNLGASYKFVREVHSVGSRVSIERFGMSFTSFKFFSEVRPDYI
KLDGSYTSNIDEDSNNKFFVRMMVDVARRIGIRVIATSVERQEEKLTLEKLLVDGLQGYYIAQPQAMAITDQI

Specific function: Serves as a specificity factor required for RNase E- mediated decay of the small global regulatory RNAs CsrB and CsrC, it is probably not a nuclease. Nor does its activity involve c-di- GMP, despite its domain composition. Positively modulates motility ge

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1789650, Length=419, Percent_Identity=24.8210023866348, Blast_Score=144, Evalue=3e-35,
Organism=Escherichia coli, GI1788849, Length=222, Percent_Identity=29.2792792792793, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI87081980, Length=234, Percent_Identity=26.4957264957265, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI87082096, Length=233, Percent_Identity=28.3261802575107, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1787541, Length=422, Percent_Identity=23.4597156398104, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787055, Length=230, Percent_Identity=26.9565217391304, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1788502, Length=207, Percent_Identity=26.0869565217391, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1790496, Length=226, Percent_Identity=21.2389380530973, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI87081845, Length=254, Percent_Identity=24.0157480314961, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786507, Length=249, Percent_Identity=24.0963855421687, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI87081921, Length=414, Percent_Identity=19.5652173913043, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 71465; Mature: 71334

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMSKSYPIFLLLIFLGLFAWVYQSENSQLQVQQQQELDSFKSSLSRYQQWQGNGVELFK
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
KLSENYSFQFFQYIDDTDGQLSHTEGSLDSQHPHPLASLFSIELSHTQKLASGRLQVKLS
HHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEC
ANQAIDTAISNTQKLGVMLLVTYLILLLVFILLMSKLRAAVRYAADYISKIPELGFSAVA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ASKLTGELTPIGISLEECRLQLKAQIDKLNQENEKLHKAAYQDAVTGFGSRQRFTQKLET
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ISHPDIPQLGLMAMVKATELTLINQKQGRSAGDDYLARVANCIRKACSKYPDAECFRVSS
CCCCCCCHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECC
ADFAVFIPDVMLKDAPKFLDQLKIYLDEYLQMTKAESVAHIGLVPYSQGIDPVNLLTIAD
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCEEEEEHHH
TAVSIAQTLGPNSYHIQEKLNGDEQFGDDRWKMAIHDLVTRQALKFYQQPIQPCRTDVEV
HHHHHHHHCCCCCEEHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRELLARFYNSEGKFLPTTTVIAMAERHGMSSELDKLVVISALKILKENPTISGNFGINI
HHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
SAFSAHQDMFVAWLKDILGKQKYIASRLVFEINESGMQSNLGASYKFVREVHSVGSRVSI
EEECCHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEH
ERFGMSFTSFKFFSEVRPDYIKLDGSYTSNIDEDSNNKFFVRMMVDVARRIGIRVIATSV
HHHCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEHHHHHHHHHHCCCEEEEHHH
ERQEEKLTLEKLLVDGLQGYYIAQPQAMAITDQI
HHHHHHHHHHHHHHHCCCCEEECCCCCEECCCCC
>Mature Secondary Structure 
AMSKSYPIFLLLIFLGLFAWVYQSENSQLQVQQQQELDSFKSSLSRYQQWQGNGVELFK
CCCCCCHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
KLSENYSFQFFQYIDDTDGQLSHTEGSLDSQHPHPLASLFSIELSHTQKLASGRLQVKLS
HHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEC
ANQAIDTAISNTQKLGVMLLVTYLILLLVFILLMSKLRAAVRYAADYISKIPELGFSAVA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ASKLTGELTPIGISLEECRLQLKAQIDKLNQENEKLHKAAYQDAVTGFGSRQRFTQKLET
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ISHPDIPQLGLMAMVKATELTLINQKQGRSAGDDYLARVANCIRKACSKYPDAECFRVSS
CCCCCCCHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECC
ADFAVFIPDVMLKDAPKFLDQLKIYLDEYLQMTKAESVAHIGLVPYSQGIDPVNLLTIAD
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCEEEEEHHH
TAVSIAQTLGPNSYHIQEKLNGDEQFGDDRWKMAIHDLVTRQALKFYQQPIQPCRTDVEV
HHHHHHHHCCCCCEEHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRELLARFYNSEGKFLPTTTVIAMAERHGMSSELDKLVVISALKILKENPTISGNFGINI
HHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
SAFSAHQDMFVAWLKDILGKQKYIASRLVFEINESGMQSNLGASYKFVREVHSVGSRVSI
EEECCHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEH
ERFGMSFTSFKFFSEVRPDYIKLDGSYTSNIDEDSNNKFFVRMMVDVARRIGIRVIATSV
HHHCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEHHHHHHHHHHCCCEEEEHHH
ERQEEKLTLEKLLVDGLQGYYIAQPQAMAITDQI
HHHHHHHHHHHHHHHCCCCEEECCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 3049542 [H]