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The map label for this gene is malZ [C]

Identifier: 160875196

GI number: 160875196

Start: 2475573

End: 2477909

Strand: Reverse

Name: malZ [C]

Synonym: Sbal195_2083

Alternate gene names: 160875196

Gene position: 2477909-2475573 (Counterclockwise)

Preceding gene: 160875197

Following gene: 160875195

Centisome position: 46.34

GC content: 47.71

Gene sequence:

>2337_bases
ATGATATTAAACCTGCGGACTCTTACCACTTCCTTAGTGATTATGCTTAGCCTAGGCACCTCTGCCAACACAGCGCAGGC
AAGTTCAAGCAGTCTCTCTTTACCACTTCAAGACACATCAAGCCAGCCTCAAGACCTGACACTTGAACCCGCTTTTTGGT
GGGCGGGGATGCACAATCCTGAGTTACAGTTGATGCTGTATAGCCGCGATTTTCCTAGCTTACCGCAGCAGCTTAAGGTT
GATATCCAAGGGCAAGGCATTACGCTAAAAAGCCTTGAATACACTGATAACCCTCACTATCTGTTTATCAATTTAGATCT
GAGCCAAGCTGCGCCGCAAACCTTTGAGCTAATAATTTCCAGCACTGACTTGGCTTCAAAAACCAGCGCTTCAAAAACCA
ACACGCCTCTTTATCGCCTGCCCTATACGTTGCAAGCGCGTGCTGAGGGCAGCCGTGAACGCAAAGGGTTTAGCAATAAA
GATGTGATTTACCTTATCACGCCTGACAGATTCGCCAATGGCGACACGAGCAATGACAATCAGGCCGATATGCTAGAGCA
AGTTGCGGCTAACTCTCCTAGCAATCTTAGCAATCCCAGCCCCCCCTATTATCCCGATGCTCGCCATGGCGGCGATATCG
CAGGGATCAGCCAGCACTTAGCATATCTGGCAAAACTCGGGGTGACTCAGTTATGGATCAATCCACTGCTTGAGAATAAT
CAAGCCCAATATTCATACCACGGATACTCGATTACCAATTTGTACCGCGTCGATCCCCGCTTTGGCAGCAACGAAGATTA
TAAAGCCTTAGTCGCTAAGGCAAACAAGCTTGGCCTTGGGGTGATTAAAGATGTTGTCGTGAATCATATCGGCTCTAATC
ATTGGTGGCTCAACGATTTACCTAGCCAAGACTGGCTCAATGGCGCCACAAAAACGCCGCTAAACAATCACGAATCCAAG
CCTGACTTGATTCAGTCTGCCGATACTAAATCCAGCACTATTAAATCCAGCGTTACCAGCCCCCGTTTCACCAGCCATAG
GCGCACTACAGTGCAAGATCCCTACGCGGCAGCGCAAGATCATATTGATTTTGTCGACGGCTGGTTTACCGACACTATGC
CGGATCTGAATCAAAGCAATCCCAAACTGGCAACCTATCTTATCCAAAACAGTATTTGGTGGGTCGAGTACGCAGGACTT
TCAGGGATCCGCGAAGATACTTATTCCTACGCCGACAAAGGGTTTCTCGCTAAATGGTCTAAGGCCGTAATGGCTGAGTA
CCCGAATTTTAATATTGTGGGCGAAGAATGGACGGCAAACCCCATCACAGTGTCCTATTGGCAAAAGGGCAAAATCAATG
CCGATGGCTATACCTCAGATTTACCCAGTTTGATGGACTTCCCGCTATATGAAAAATTGATTGCCAGCCTCAATGAGCCA
GAAAGCTGGGACACAGGTTTTATCAAGCTTTATGAGATGTTAGCCAACGATGTTGTGTATGCCGACCCCAGTAAACTAGT
GCTATTTGAAGGCAATCACGACACCAATCGTATCTTCAGTTTAGTTAAAGAAAATATAGACTTATACAAGATGGCACTCA
CCTATGTGCTGACCGCCAAACGCATTCCGCAGCTGTTCTACGGTACTGAAGTGTTAATGACCAGCCCGACAGAAGGCCGT
CACGATGGTGTTGTGCGCAGTGATTTCCCCGGTGGGTTTGCCAACAGTGCCACTAACGCCTTTACCGGCCAAGGACTGAG
TGAACCCCAGCGACAAGCACAGCACTTTGTCCGTACCCTACTGAATTACCGTAAACAATCTCCTGCGCTACAATCGGGCG
ATTTACTGCACTTTGTACCGCAAGATGGTGTCTATGTGCAATTTCGTTGCGCATTAAATGCGCCATTATCAGCTGAACAG
AAAGCCGAGGCGCTCAAGTCACGAATACAAAACAATTCTCTAACCCAACACAATGCCTGCACTCAGCCCTCGGCCGATAA
AGTCATGGTGATTTACAATAAGAATGACAAGGCAGTCACGCTAGATATAAACCGCTTTGCCAGTGTACTTGGCGATAGCG
GCGCCGCTACAGATATCATCAGTGGCAAAACAGTTTCACTCAATCAAGCGATAACATTGCCCCACGCAGGGGTTACTATC
CTTGAGCTTAAGCCTAATTCTAAGACTAAGACTAAGTCGCCGCAGAATGCTGGCTTGCCGAGCCGCCAAGATTCAATGTA
CCCGGGGAACCAAACTAACGCTTTAACGCGCGCTCATACTAACAACAGTGCTAACAACCTAGCCAAACACTCAACTCAAA
AAGGAACTCAGTCTTGA

Upstream 100 bases:

>100_bases
TAAATACGGCTTAAGAGTTACGACCGACGTTAATAGTGTACTAACTCATCGATTTATAAATTGAATTTGCAGTTTAAATT
TGAATCAACAAGGAAAGAAT

Downstream 100 bases:

>100_bases
GCTTTTTATCACCTATCGATTCCAGAGTGACTCAGATCCAACAAGCGGCTAAATTTCCCATCGTAGCTTTACTGACCAAA
GCAGCGAAAGCCCCGCAGCG

Product: alpha amylase catalytic subunit

Products: NA

Alternate protein names: Beta-amylase; Alpha-amylase [H]

Number of amino acids: Translated: 778; Mature: 778

Protein sequence:

>778_residues
MILNLRTLTTSLVIMLSLGTSANTAQASSSSLSLPLQDTSSQPQDLTLEPAFWWAGMHNPELQLMLYSRDFPSLPQQLKV
DIQGQGITLKSLEYTDNPHYLFINLDLSQAAPQTFELIISSTDLASKTSASKTNTPLYRLPYTLQARAEGSRERKGFSNK
DVIYLITPDRFANGDTSNDNQADMLEQVAANSPSNLSNPSPPYYPDARHGGDIAGISQHLAYLAKLGVTQLWINPLLENN
QAQYSYHGYSITNLYRVDPRFGSNEDYKALVAKANKLGLGVIKDVVVNHIGSNHWWLNDLPSQDWLNGATKTPLNNHESK
PDLIQSADTKSSTIKSSVTSPRFTSHRRTTVQDPYAAAQDHIDFVDGWFTDTMPDLNQSNPKLATYLIQNSIWWVEYAGL
SGIREDTYSYADKGFLAKWSKAVMAEYPNFNIVGEEWTANPITVSYWQKGKINADGYTSDLPSLMDFPLYEKLIASLNEP
ESWDTGFIKLYEMLANDVVYADPSKLVLFEGNHDTNRIFSLVKENIDLYKMALTYVLTAKRIPQLFYGTEVLMTSPTEGR
HDGVVRSDFPGGFANSATNAFTGQGLSEPQRQAQHFVRTLLNYRKQSPALQSGDLLHFVPQDGVYVQFRCALNAPLSAEQ
KAEALKSRIQNNSLTQHNACTQPSADKVMVIYNKNDKAVTLDINRFASVLGDSGAATDIISGKTVSLNQAITLPHAGVTI
LELKPNSKTKTKSPQNAGLPSRQDSMYPGNQTNALTRAHTNNSANNLAKHSTQKGTQS

Sequences:

>Translated_778_residues
MILNLRTLTTSLVIMLSLGTSANTAQASSSSLSLPLQDTSSQPQDLTLEPAFWWAGMHNPELQLMLYSRDFPSLPQQLKV
DIQGQGITLKSLEYTDNPHYLFINLDLSQAAPQTFELIISSTDLASKTSASKTNTPLYRLPYTLQARAEGSRERKGFSNK
DVIYLITPDRFANGDTSNDNQADMLEQVAANSPSNLSNPSPPYYPDARHGGDIAGISQHLAYLAKLGVTQLWINPLLENN
QAQYSYHGYSITNLYRVDPRFGSNEDYKALVAKANKLGLGVIKDVVVNHIGSNHWWLNDLPSQDWLNGATKTPLNNHESK
PDLIQSADTKSSTIKSSVTSPRFTSHRRTTVQDPYAAAQDHIDFVDGWFTDTMPDLNQSNPKLATYLIQNSIWWVEYAGL
SGIREDTYSYADKGFLAKWSKAVMAEYPNFNIVGEEWTANPITVSYWQKGKINADGYTSDLPSLMDFPLYEKLIASLNEP
ESWDTGFIKLYEMLANDVVYADPSKLVLFEGNHDTNRIFSLVKENIDLYKMALTYVLTAKRIPQLFYGTEVLMTSPTEGR
HDGVVRSDFPGGFANSATNAFTGQGLSEPQRQAQHFVRTLLNYRKQSPALQSGDLLHFVPQDGVYVQFRCALNAPLSAEQ
KAEALKSRIQNNSLTQHNACTQPSADKVMVIYNKNDKAVTLDINRFASVLGDSGAATDIISGKTVSLNQAITLPHAGVTI
LELKPNSKTKTKSPQNAGLPSRQDSMYPGNQTNALTRAHTNNSANNLAKHSTQKGTQS
>Mature_778_residues
MILNLRTLTTSLVIMLSLGTSANTAQASSSSLSLPLQDTSSQPQDLTLEPAFWWAGMHNPELQLMLYSRDFPSLPQQLKV
DIQGQGITLKSLEYTDNPHYLFINLDLSQAAPQTFELIISSTDLASKTSASKTNTPLYRLPYTLQARAEGSRERKGFSNK
DVIYLITPDRFANGDTSNDNQADMLEQVAANSPSNLSNPSPPYYPDARHGGDIAGISQHLAYLAKLGVTQLWINPLLENN
QAQYSYHGYSITNLYRVDPRFGSNEDYKALVAKANKLGLGVIKDVVVNHIGSNHWWLNDLPSQDWLNGATKTPLNNHESK
PDLIQSADTKSSTIKSSVTSPRFTSHRRTTVQDPYAAAQDHIDFVDGWFTDTMPDLNQSNPKLATYLIQNSIWWVEYAGL
SGIREDTYSYADKGFLAKWSKAVMAEYPNFNIVGEEWTANPITVSYWQKGKINADGYTSDLPSLMDFPLYEKLIASLNEP
ESWDTGFIKLYEMLANDVVYADPSKLVLFEGNHDTNRIFSLVKENIDLYKMALTYVLTAKRIPQLFYGTEVLMTSPTEGR
HDGVVRSDFPGGFANSATNAFTGQGLSEPQRQAQHFVRTLLNYRKQSPALQSGDLLHFVPQDGVYVQFRCALNAPLSAEQ
KAEALKSRIQNNSLTQHNACTQPSADKVMVIYNKNDKAVTLDINRFASVLGDSGAATDIISGKTVSLNQAITLPHAGVTI
LELKPNSKTKTKSPQNAGLPSRQDSMYPGNQTNALTRAHTNNSANNLAKHSTQKGTQS

Specific function: The precursor protein is proteolytically cleaved to produce multiform beta-amylases and a 48 kDa alpha-amylase after secretion [H]

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Escherichia coli, GI1786604, Length=488, Percent_Identity=24.5901639344262, Blast_Score=90, Evalue=6e-19,
Organism=Escherichia coli, GI1790687, Length=211, Percent_Identity=27.0142180094787, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1789995, Length=145, Percent_Identity=30.3448275862069, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321726, Length=204, Percent_Identity=28.921568627451, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324416, Length=204, Percent_Identity=28.4313725490196, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322241, Length=204, Percent_Identity=28.4313725490196, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322021, Length=204, Percent_Identity=28.4313725490196, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322245, Length=102, Percent_Identity=37.2549019607843, Blast_Score=81, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6321731, Length=102, Percent_Identity=36.2745098039216, Blast_Score=78, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6319776, Length=102, Percent_Identity=36.2745098039216, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24586587, Length=271, Percent_Identity=24.7232472324723, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24583745, Length=217, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24586589, Length=92, Percent_Identity=36.9565217391304, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24586591, Length=84, Percent_Identity=39.2857142857143, Blast_Score=74, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24586599, Length=204, Percent_Identity=25, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45549022, Length=200, Percent_Identity=25, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24586597, Length=87, Percent_Identity=35.632183908046, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24583749, Length=209, Percent_Identity=24.8803827751196, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24583747, Length=209, Percent_Identity=24.8803827751196, Blast_Score=70, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006048
- InterPro:   IPR005085
- InterPro:   IPR008985
- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR001554
- InterPro:   IPR018238
- InterPro:   IPR000125
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase; PF03423 CBM_25; PF01373 Glyco_hydro_14 [H]

EC number: =3.2.1.2; =3.2.1.1 [H]

Molecular weight: Translated: 86158; Mature: 86158

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILNLRTLTTSLVIMLSLGTSANTAQASSSSLSLPLQDTSSQPQDLTLEPAFWWAGMHNP
CEEEEHHHHHHEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCCCEEECCHHEECCCCCC
ELQLMLYSRDFPSLPQQLKVDIQGQGITLKSLEYTDNPHYLFINLDLSQAAPQTFELIIS
CEEEEEEECCCCCCCCCEEEEECCCCEEEEEEEECCCCCEEEEEECHHHCCCCEEEEEEE
STDLASKTSASKTNTPLYRLPYTLQARAEGSRERKGFSNKDVIYLITPDRFANGDTSNDN
CCCCCCCCCCCCCCCCEEECCEEEEECCCCCHHHCCCCCCCEEEEECCCCCCCCCCCCCC
QADMLEQVAANSPSNLSNPSPPYYPDARHGGDIAGISQHLAYLAKLGVTQLWINPLLENN
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHCCC
QAQYSYHGYSITNLYRVDPRFGSNEDYKALVAKANKLGLGVIKDVVVNHIGSNHWWLNDL
CCEEEECCEEEEEEEEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCC
PSQDWLNGATKTPLNNHESKPDLIQSADTKSSTIKSSVTSPRFTSHRRTTVQDPYAAAQD
CCHHHCCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
HIDFVDGWFTDTMPDLNQSNPKLATYLIQNSIWWVEYAGLSGIREDTYSYADKGFLAKWS
CCHHHCCCCCCCCCCCCCCCCCEEEEEECCCEEEEEECCCCCCHHHHHHHHCCCHHHHHH
KAVMAEYPNFNIVGEEWTANPITVSYWQKGKINADGYTSDLPSLMDFPLYEKLIASLNEP
HHHHHCCCCCEEECCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHCCHHHHHHHHHCCCC
ESWDTGFIKLYEMLANDVVYADPSKLVLFEGNHDTNRIFSLVKENIDLYKMALTYVLTAK
CCCCHHHHHHHHHHHCCEEEECCCEEEEEECCCCHHHHHHHHHHCHHHHHHHHHHHHHHH
RIPQLFYGTEVLMTSPTEGRHDGVVRSDFPGGFANSATNAFTGQGLSEPQRQAQHFVRTL
HHHHHHCCCEEEEECCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
LNYRKQSPALQSGDLLHFVPQDGVYVQFRCALNAPLSAEQKAEALKSRIQNNSLTQHNAC
HHHHHCCCCCCCCCEEEECCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCC
TQPSADKVMVIYNKNDKAVTLDINRFASVLGDSGAATDIISGKTVSLNQAITLPHAGVTI
CCCCCCCEEEEEECCCCEEEEEHHHHHHHHCCCCCCCCCCCCCEEECCCEEECCCCCEEE
LELKPNSKTKTKSPQNAGLPSRQDSMYPGNQTNALTRAHTNNSANNLAKHSTQKGTQS
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHCCCCCCCC
>Mature Secondary Structure
MILNLRTLTTSLVIMLSLGTSANTAQASSSSLSLPLQDTSSQPQDLTLEPAFWWAGMHNP
CEEEEHHHHHHEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCCCEEECCHHEECCCCCC
ELQLMLYSRDFPSLPQQLKVDIQGQGITLKSLEYTDNPHYLFINLDLSQAAPQTFELIIS
CEEEEEEECCCCCCCCCEEEEECCCCEEEEEEEECCCCCEEEEEECHHHCCCCEEEEEEE
STDLASKTSASKTNTPLYRLPYTLQARAEGSRERKGFSNKDVIYLITPDRFANGDTSNDN
CCCCCCCCCCCCCCCCEEECCEEEEECCCCCHHHCCCCCCCEEEEECCCCCCCCCCCCCC
QADMLEQVAANSPSNLSNPSPPYYPDARHGGDIAGISQHLAYLAKLGVTQLWINPLLENN
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHCCC
QAQYSYHGYSITNLYRVDPRFGSNEDYKALVAKANKLGLGVIKDVVVNHIGSNHWWLNDL
CCEEEECCEEEEEEEEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCC
PSQDWLNGATKTPLNNHESKPDLIQSADTKSSTIKSSVTSPRFTSHRRTTVQDPYAAAQD
CCHHHCCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
HIDFVDGWFTDTMPDLNQSNPKLATYLIQNSIWWVEYAGLSGIREDTYSYADKGFLAKWS
CCHHHCCCCCCCCCCCCCCCCCEEEEEECCCEEEEEECCCCCCHHHHHHHHCCCHHHHHH
KAVMAEYPNFNIVGEEWTANPITVSYWQKGKINADGYTSDLPSLMDFPLYEKLIASLNEP
HHHHHCCCCCEEECCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHCCHHHHHHHHHCCCC
ESWDTGFIKLYEMLANDVVYADPSKLVLFEGNHDTNRIFSLVKENIDLYKMALTYVLTAK
CCCCHHHHHHHHHHHCCEEEECCCEEEEEECCCCHHHHHHHHHHCHHHHHHHHHHHHHHH
RIPQLFYGTEVLMTSPTEGRHDGVVRSDFPGGFANSATNAFTGQGLSEPQRQAQHFVRTL
HHHHHHCCCEEEEECCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
LNYRKQSPALQSGDLLHFVPQDGVYVQFRCALNAPLSAEQKAEALKSRIQNNSLTQHNAC
HHHHHCCCCCCCCCEEEECCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCC
TQPSADKVMVIYNKNDKAVTLDINRFASVLGDSGAATDIISGKTVSLNQAITLPHAGVTI
CCCCCCCEEEEEECCCCEEEEEHHHHHHHHCCCCCCCCCCCCCEEECCCEEECCCCCEEE
LELKPNSKTKTKSPQNAGLPSRQDSMYPGNQTNALTRAHTNNSANNLAKHSTQKGTQS
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2435707; 2464578; 2438660; 1827035 [H]