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The map label for this gene is umuD [H]

Identifier: 160875153

GI number: 160875153

Start: 2420344

End: 2420751

Strand: Direct

Name: umuD [H]

Synonym: Sbal195_2039

Alternate gene names: 160875153

Gene position: 2420344-2420751 (Clockwise)

Preceding gene: 160875151

Following gene: 160875154

Centisome position: 45.26

GC content: 44.61

Gene sequence:

>408_bases
ATGCGTATTATCCCCATCTATGCCAGTGCCGGTATTACTGGCTTCGAAAGCCCTGCGGCTGAATATAGTCAGCTGGGTCT
CAGCCTTGATGAGTTGTTAGTTGTTCATCCCAGCGCGACTTTTATTGGTGTCGCAAAAGGTGACTCAATGCAGGGCGTGG
GCATTTTTTATGGCGATATATTGATTGTTGACCGTCAGGAAACTGCGCGTCATGGTGATGTGATTGTTGCCAATTTCAAC
GGTGAATTTGTATGTAAAATCCTCGATAAAACGCATCGCATGCTGCTGTCATCGAATGAACAGCACCAACCTCAGCCTAT
TCATGATTACGATAACTTTACCATTGAAGGTGTTGTTATTCGTTCTGTTCGTTGTCATCGCCAAAGTCCATTATTAGCGG
ATATCTGA

Upstream 100 bases:

>100_bases
AGAAAAGAACCAATGGTGTTACATCGAAACATCACAATAATTCTTGCCAGTTATCTAACAACGCCTATAATTACTGTATA
TAAAAACAGTGGTGTTAACT

Downstream 100 bases:

>100_bases
TGTTTGCCTTGGTTGACGCCAACAGTTTTTATTGCAGTGCCGAGCAGGTATTTAGACCTGATTGGCGTGGTAAGCCAATG
ATTGTGTTGAGCAACAATGA

Product: peptidase S24/S26 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 135; Mature: 135

Protein sequence:

>135_residues
MRIIPIYASAGITGFESPAAEYSQLGLSLDELLVVHPSATFIGVAKGDSMQGVGIFYGDILIVDRQETARHGDVIVANFN
GEFVCKILDKTHRMLLSSNEQHQPQPIHDYDNFTIEGVVIRSVRCHRQSPLLADI

Sequences:

>Translated_135_residues
MRIIPIYASAGITGFESPAAEYSQLGLSLDELLVVHPSATFIGVAKGDSMQGVGIFYGDILIVDRQETARHGDVIVANFN
GEFVCKILDKTHRMLLSSNEQHQPQPIHDYDNFTIEGVVIRSVRCHRQSPLLADI
>Mature_135_residues
MRIIPIYASAGITGFESPAAEYSQLGLSLDELLVVHPSATFIGVAKGDSMQGVGIFYGDILIVDRQETARHGDVIVANFN
GEFVCKILDKTHRMLLSSNEQHQPQPIHDYDNFTIEGVVIRSVRCHRQSPLLADI

Specific function: Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template [H]

COG id: COG1974

COG function: function code KT; SOS-response transcriptional repressors (RecA-mediated autopeptidases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S24 family [H]

Homologues:

Organism=Escherichia coli, GI1787431, Length=124, Percent_Identity=41.1290322580645, Blast_Score=92, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006197
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 14893; Mature: 14893

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIIPIYASAGITGFESPAAEYSQLGLSLDELLVVHPSATFIGVAKGDSMQGVGIFYGDI
CEEEEEEECCCCCCCCCCHHHHHHHCCCHHHEEEECCCCEEEEEECCCCCCCEEEEEEEE
LIVDRQETARHGDVIVANFNGEFVCKILDKTHRMLLSSNEQHQPQPIHDYDNFTIEGVVI
EEEECCCCCCCCCEEEEECCCCEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEE
RSVRCHRQSPLLADI
EEEECCCCCCCCCCC
>Mature Secondary Structure
MRIIPIYASAGITGFESPAAEYSQLGLSLDELLVVHPSATFIGVAKGDSMQGVGIFYGDI
CEEEEEEECCCCCCCCCCHHHHHHHCCCHHHEEEECCCCEEEEEECCCCCCCEEEEEEEE
LIVDRQETARHGDVIVANFNGEFVCKILDKTHRMLLSSNEQHQPQPIHDYDNFTIEGVVI
EEEECCCCCCCCCEEEEECCCCEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEE
RSVRCHRQSPLLADI
EEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]