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The map label for this gene is chvG [H]

Identifier: 160874989

GI number: 160874989

Start: 2239992

End: 2242160

Strand: Reverse

Name: chvG [H]

Synonym: Sbal195_1874

Alternate gene names: 160874989

Gene position: 2242160-2239992 (Counterclockwise)

Preceding gene: 160874990

Following gene: 160874988

Centisome position: 41.93

GC content: 50.35

Gene sequence:

>2169_bases
ATGACACGTTTCCCCTTTGGTCTACGCACTAAAGTCATCGGCCTTAGCCTATTTTTGCTCTGCCTACCTTGGCTGGGGTA
CCAATATGTGTGGGAGATGGAAAAGTATCTTCGCCACGGTCAAGAACGCACCTTAGAAGGCACCACTCAGGCATTGGCCA
CCGCACTGCACGAACGGCCGAAATTGTTCGATGGACAAGCGAGCTTTTTAAAGCAAGTGGAAAAGAGTCGCGATCTGTAC
GCCTATCAACTCAATGGGGCGATTCTGCTCGACGGCAAACTTAACGAATGGGAAGAGTATCAGCACAGATTTATCCAGTA
CGGTGAGGCGCATCAGATCATGCGCGCCGAGCCTAACGCGCCGCTGACCTTAAGCTTTACCCACATGGTCGGCCAGTACG
ATGGTTATCTGTATGCCTTCTTTCAAGTGACCGACCCAACTGTGGTGCTGCGTGGCAAAAATGCGTTAAGTGTCGATAGA
AACGATCATCTCTCGATTGCGACACTCGCGCCCGACAATAAATTCAAGCGCTATATCGTTGCCACCACGCAACCCGGCTG
GATCAGTGCCTTCGAGTTACCTGCCAATCCTAAGCAAACCGTGCCCGTCAAACCTGAAGTGCGCATACAAGGACAATGGG
CGACCACAGATGTGGGCTACAATGTCGAGCTGCGTATTCCCTTAGACATGGTCGGCAGCAAACTCGGTTTTGCCATTTCC
GATGTTAACGACAGCAAAAACCGCGATGTGGCAGCCGTTGTCGGCACCTCGGCCTTAGATACGGTCGATAATCTCGGCAC
TGTGTTGGTGCCATCGCCAGAAATTGAAAACATTATCAAAGGCATGAGCCACTATAGCTCACGCATTTGGGTAGTCGATA
AGCACGGCCGCGTACTGGCAAAATCGGGCGATATTCGTGCCAATGATAGCGTGTGGACCCGCACCTTAGAAGATGAAAAG
AGCACCACGCTATGGGAAACCTTCAAGCGCGATTACTTGCATCCGCTGTACTATAAAATCCTCACTAAGCCGCCCAAAGA
CTTTATCGACTCCTTGCAAGACTCCACCGAGCTTGATGGCAGTCATATCCAAAAAGCACTAGCTGGTCAGCAAAGTTCAA
CTTGGCGCTTAACCCCAGACAATAAAGCTGTGGTACTTGCCGCCGCCAGCCCTATTTGGATAGATAACAATGTGATGGGC
GCCGTTGTCGCCGAAGAAACCACCCACGGGATCCGTACCCTGCGTAACCGCGCGCTGGAAAAACTCTTTAACGTGATTTT
GACCATTATGAGCATGGGCACTTTGGCGCTGTTCTTTTTCGCTTCGAGCATTTCTAACCGTATCCGTAAACTGCGCGATG
AGGCCGAAAATGCCATTGATAGCCAAGGCCGCGTTCGTAATCACCTCAAACCGTCTAAAGCTCGGGATGAAATTGGCGAT
CTGTCCCGCAGTTTCTCCAACATTGTCGGACGGCTTGGTCAATACACACATTATCTGGAAAATATGTCGTCGCGCCTGTC
CCATGAGCTGCGCACGCCCGTGGCGGTTGTGCGATCATCCCTTGAGCATTTAAACCTGCAAACCTTAGATAAAGACACGC
AGAAATATGTCGACCGCGCCCAAGAAGGTGTCAGCCGCTTAAGCATGATTTTAAATAACATGAGCGAAGCAACGCGCTTA
GAGCAGAGTTTAACGCAGGCCGATATCACTAAATTCCCACTCTCCCAAGTGGTTAGCGGTTGTATGCAAGGTTATCAAAT
GACCTATCCAGAACAAGGCTTTAGCGTAAAAGTGCCCGAGCAACCTCTGATGATGCAAGGTGTGCCGGAATATATCGCCC
AGTTGATGGACAAACTTATCGCTAACGCGATTGAATTTTGCGATAAAGGCAGCGCCATCGAAGTCACGCTCACCCAAGTC
GGTAAGCAAGCAACTTTGCTTATCAGTAACTTAGGACCAGAACTGCCCGTTGATATGTCGGAGCAGATTTTCGACTCCAT
GGTGTCGGTGCGGATAAATCAAGCCCAAGACAAACCTCATCTCGGTTTAGGTCTGTATATCGCACGATTGGTCGCCGAGT
TCCACCAAGGACAAATCCTCGCCCGCAATCGCAGCGAGCATAATGGCGTCGATATCCTAGTAACCTTGCCTTTGAGCCCT
GCTTCATAA

Upstream 100 bases:

>100_bases
GTTATCGCTGGGACAGCTTAGCCTGAACTCTCGCGATACCTTGATGCACGTAACCTTGAGCCAATACACTTTTGATCCCA
TTGATGCTGATCCCTAACTT

Downstream 100 bases:

>100_bases
TCTAAAGACCGAAGGGACAGGAGCCAATAACATGAGTCAAACTCATCATCGCGCCTCCTGTCATTTCTGCGTGCAGATGC
TAAGATGACCGCCATAACAA

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Histidine kinase sensory protein ExoS [H]

Number of amino acids: Translated: 722; Mature: 721

Protein sequence:

>722_residues
MTRFPFGLRTKVIGLSLFLLCLPWLGYQYVWEMEKYLRHGQERTLEGTTQALATALHERPKLFDGQASFLKQVEKSRDLY
AYQLNGAILLDGKLNEWEEYQHRFIQYGEAHQIMRAEPNAPLTLSFTHMVGQYDGYLYAFFQVTDPTVVLRGKNALSVDR
NDHLSIATLAPDNKFKRYIVATTQPGWISAFELPANPKQTVPVKPEVRIQGQWATTDVGYNVELRIPLDMVGSKLGFAIS
DVNDSKNRDVAAVVGTSALDTVDNLGTVLVPSPEIENIIKGMSHYSSRIWVVDKHGRVLAKSGDIRANDSVWTRTLEDEK
STTLWETFKRDYLHPLYYKILTKPPKDFIDSLQDSTELDGSHIQKALAGQQSSTWRLTPDNKAVVLAAASPIWIDNNVMG
AVVAEETTHGIRTLRNRALEKLFNVILTIMSMGTLALFFFASSISNRIRKLRDEAENAIDSQGRVRNHLKPSKARDEIGD
LSRSFSNIVGRLGQYTHYLENMSSRLSHELRTPVAVVRSSLEHLNLQTLDKDTQKYVDRAQEGVSRLSMILNNMSEATRL
EQSLTQADITKFPLSQVVSGCMQGYQMTYPEQGFSVKVPEQPLMMQGVPEYIAQLMDKLIANAIEFCDKGSAIEVTLTQV
GKQATLLISNLGPELPVDMSEQIFDSMVSVRINQAQDKPHLGLGLYIARLVAEFHQGQILARNRSEHNGVDILVTLPLSP
AS

Sequences:

>Translated_722_residues
MTRFPFGLRTKVIGLSLFLLCLPWLGYQYVWEMEKYLRHGQERTLEGTTQALATALHERPKLFDGQASFLKQVEKSRDLY
AYQLNGAILLDGKLNEWEEYQHRFIQYGEAHQIMRAEPNAPLTLSFTHMVGQYDGYLYAFFQVTDPTVVLRGKNALSVDR
NDHLSIATLAPDNKFKRYIVATTQPGWISAFELPANPKQTVPVKPEVRIQGQWATTDVGYNVELRIPLDMVGSKLGFAIS
DVNDSKNRDVAAVVGTSALDTVDNLGTVLVPSPEIENIIKGMSHYSSRIWVVDKHGRVLAKSGDIRANDSVWTRTLEDEK
STTLWETFKRDYLHPLYYKILTKPPKDFIDSLQDSTELDGSHIQKALAGQQSSTWRLTPDNKAVVLAAASPIWIDNNVMG
AVVAEETTHGIRTLRNRALEKLFNVILTIMSMGTLALFFFASSISNRIRKLRDEAENAIDSQGRVRNHLKPSKARDEIGD
LSRSFSNIVGRLGQYTHYLENMSSRLSHELRTPVAVVRSSLEHLNLQTLDKDTQKYVDRAQEGVSRLSMILNNMSEATRL
EQSLTQADITKFPLSQVVSGCMQGYQMTYPEQGFSVKVPEQPLMMQGVPEYIAQLMDKLIANAIEFCDKGSAIEVTLTQV
GKQATLLISNLGPELPVDMSEQIFDSMVSVRINQAQDKPHLGLGLYIARLVAEFHQGQILARNRSEHNGVDILVTLPLSP
AS
>Mature_721_residues
TRFPFGLRTKVIGLSLFLLCLPWLGYQYVWEMEKYLRHGQERTLEGTTQALATALHERPKLFDGQASFLKQVEKSRDLYA
YQLNGAILLDGKLNEWEEYQHRFIQYGEAHQIMRAEPNAPLTLSFTHMVGQYDGYLYAFFQVTDPTVVLRGKNALSVDRN
DHLSIATLAPDNKFKRYIVATTQPGWISAFELPANPKQTVPVKPEVRIQGQWATTDVGYNVELRIPLDMVGSKLGFAISD
VNDSKNRDVAAVVGTSALDTVDNLGTVLVPSPEIENIIKGMSHYSSRIWVVDKHGRVLAKSGDIRANDSVWTRTLEDEKS
TTLWETFKRDYLHPLYYKILTKPPKDFIDSLQDSTELDGSHIQKALAGQQSSTWRLTPDNKAVVLAAASPIWIDNNVMGA
VVAEETTHGIRTLRNRALEKLFNVILTIMSMGTLALFFFASSISNRIRKLRDEAENAIDSQGRVRNHLKPSKARDEIGDL
SRSFSNIVGRLGQYTHYLENMSSRLSHELRTPVAVVRSSLEHLNLQTLDKDTQKYVDRAQEGVSRLSMILNNMSEATRLE
QSLTQADITKFPLSQVVSGCMQGYQMTYPEQGFSVKVPEQPLMMQGVPEYIAQLMDKLIANAIEFCDKGSAIEVTLTQVG
KQATLLISNLGPELPVDMSEQIFDSMVSVRINQAQDKPHLGLGLYIARLVAEFHQGQILARNRSEHNGVDILVTLPLSPA
S

Specific function: Member of a two-component regulatory system ChvG(ExoS)/ChvI involved in regulating the production of succinoglycan. Activates ChvI by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=250, Percent_Identity=24.8, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1786912, Length=216, Percent_Identity=25.9259259259259, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790346, Length=276, Percent_Identity=25, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 81085; Mature: 80953

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRFPFGLRTKVIGLSLFLLCLPWLGYQYVWEMEKYLRHGQERTLEGTTQALATALHERP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCHHHHHHHHHHHHHHCC
KLFDGQASFLKQVEKSRDLYAYQLNGAILLDGKLNEWEEYQHRFIQYGEAHQIMRAEPNA
CCCCCHHHHHHHHHHCCCEEEEEECCEEEECCCCCHHHHHHHHHHHCCCHHHHHCCCCCC
PLTLSFTHMVGQYDGYLYAFFQVTDPTVVLRGKNALSVDRNDHLSIATLAPDNKFKRYIV
CEEEEHHHHHHCCCCEEEEEEEECCCEEEEECCCEEECCCCCCEEEEEECCCCCCCEEEE
ATTQPGWISAFELPANPKQTVPVKPEVRIQGQWATTDVGYNVELRIPLDMVGSKLGFAIS
EECCCCCEEEEECCCCCCCCCCCCCCEEEECEEEEECCCEEEEEEECHHHHCCHHCEEEE
DVNDSKNRDVAAVVGTSALDTVDNLGTVLVPSPEIENIIKGMSHYSSRIWVVDKHGRVLA
CCCCCCCCCEEEEECCHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCEEEEEECCCEEEE
KSGDIRANDSVWTRTLEDEKSTTLWETFKRDYLHPLYYKILTKPPKDFIDSLQDSTELDG
ECCCCCCCCCHHHEECCCCCCHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHCCCCCCH
SHIQKALAGQQSSTWRLTPDNKAVVLAAASPIWIDNNVMGAVVAEETTHGIRTLRNRALE
HHHHHHHCCCCCCCEEECCCCCEEEEEECCCEEECCCCEEEEEEHHHHHHHHHHHHHHHH
KLFNVILTIMSMGTLALFFFASSISNRIRKLRDEAENAIDSQGRVRNHLKPSKARDEIGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHH
LSRSFSNIVGRLGQYTHYLENMSSRLSHELRTPVAVVRSSLEHLNLQTLDKDTQKYVDRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
QEGVSRLSMILNNMSEATRLEQSLTQADITKFPLSQVVSGCMQGYQMTYPEQGFSVKVPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEECCCCCCCEEECCC
QPLMMQGVPEYIAQLMDKLIANAIEFCDKGSAIEVTLTQVGKQATLLISNLGPELPVDMS
CCHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHCCCHHEEEEECCCCCCCCCHH
EQIFDSMVSVRINQAQDKPHLGLGLYIARLVAEFHQGQILARNRSEHNGVDILVTLPLSP
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCEEEEEEECCCC
AS
CC
>Mature Secondary Structure 
TRFPFGLRTKVIGLSLFLLCLPWLGYQYVWEMEKYLRHGQERTLEGTTQALATALHERP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCHHHHHHHHHHHHHHCC
KLFDGQASFLKQVEKSRDLYAYQLNGAILLDGKLNEWEEYQHRFIQYGEAHQIMRAEPNA
CCCCCHHHHHHHHHHCCCEEEEEECCEEEECCCCCHHHHHHHHHHHCCCHHHHHCCCCCC
PLTLSFTHMVGQYDGYLYAFFQVTDPTVVLRGKNALSVDRNDHLSIATLAPDNKFKRYIV
CEEEEHHHHHHCCCCEEEEEEEECCCEEEEECCCEEECCCCCCEEEEEECCCCCCCEEEE
ATTQPGWISAFELPANPKQTVPVKPEVRIQGQWATTDVGYNVELRIPLDMVGSKLGFAIS
EECCCCCEEEEECCCCCCCCCCCCCCEEEECEEEEECCCEEEEEEECHHHHCCHHCEEEE
DVNDSKNRDVAAVVGTSALDTVDNLGTVLVPSPEIENIIKGMSHYSSRIWVVDKHGRVLA
CCCCCCCCCEEEEECCHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCEEEEEECCCEEEE
KSGDIRANDSVWTRTLEDEKSTTLWETFKRDYLHPLYYKILTKPPKDFIDSLQDSTELDG
ECCCCCCCCCHHHEECCCCCCHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHCCCCCCH
SHIQKALAGQQSSTWRLTPDNKAVVLAAASPIWIDNNVMGAVVAEETTHGIRTLRNRALE
HHHHHHHCCCCCCCEEECCCCCEEEEEECCCEEECCCCEEEEEEHHHHHHHHHHHHHHHH
KLFNVILTIMSMGTLALFFFASSISNRIRKLRDEAENAIDSQGRVRNHLKPSKARDEIGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHH
LSRSFSNIVGRLGQYTHYLENMSSRLSHELRTPVAVVRSSLEHLNLQTLDKDTQKYVDRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
QEGVSRLSMILNNMSEATRLEQSLTQADITKFPLSQVVSGCMQGYQMTYPEQGFSVKVPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEECCCCCCCEEECCC
QPLMMQGVPEYIAQLMDKLIANAIEFCDKGSAIEVTLTQVGKQATLLISNLGPELPVDMS
CCHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHCCCHHEEEEECCCCCCCCCHH
EQIFDSMVSVRINQAQDKPHLGLGLYIARLVAEFHQGQILARNRSEHNGVDILVTLPLSP
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCEEEEEEECCCC
AS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9422587; 11481430; 7559334 [H]