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The map label for this gene is ahpC [C]

Identifier: 160874892

GI number: 160874892

Start: 2130998

End: 2131603

Strand: Direct

Name: ahpC [C]

Synonym: Sbal195_1777

Alternate gene names: 160874892

Gene position: 2130998-2131603 (Clockwise)

Preceding gene: 160874890

Following gene: 160874894

Centisome position: 39.85

GC content: 47.03

Gene sequence:

>606_bases
ATGAGCGTATTAGTAGGCCGTCAGGCTCCTGATTTTACTGCTGCAGCTGTATTAGGTTCTGGCGAAATCGTTGATAGCTT
CAACTTAACTGCAGCCATCAAAGGCAAACCAGCAGTCGTATTCTTCTATCCACTTGACTTCACTTTCGTTTGTCCATCAG
AGTTGATCGCATTTGATCACCGCATGGAAGAGTTCACTAAGCGTGGCGTAGAAGTGATCGGTGTGTCTATCGATTCTCAG
TTCACTCACAACGCATGGCGCAACACCCCAGTTGAAAAAGGCGGTATTGGCCAAGTTAAGTACACGCTAGTGGCTGACGT
TAAACATGAAATCTGTAAAGCATACGATGTTGAGCATCCAGAAGCGGGTGTGGCTTTCCGTGGTTCATTCCTGATCGACA
AAGAAGGCATGGTTCGTCACCAAGTTGTTAACGATCTGCCATTAGGCCGTAACGTTGATGAAATGCTACGTATGATCGAC
GCACTGCAATTCCACGAAGAGCACGGCGATGTATGTCCTGCTGGCTGGGAAAAAGGCGATAAAGGTATGAATGCAAGCAC
TGAAGGTGTTGCTGCTTACCTGTCTGAAAACGCAAGCTCACTGTAA

Upstream 100 bases:

>100_bases
TTAATCAGTAAAGATTTAACTCGACCTAGGTTGAGGTGAGCATACTGGCGAAAGGGCATCTTGCCTTACACTTAGTTCAA
CTCATAGATGGAGATATAAA

Downstream 100 bases:

>100_bases
TTAGTATTTACTAATCACAGTTGCTCGTTAAATGAAAAAAGCTGCCAATGGCAGCTTTTTTGTTTTTAAATGGCTTAAGA
TCTAGTGTGAACCGCTAAAT

Product: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MSVLVGRQAPDFTAAAVLGSGEIVDSFNLTAAIKGKPAVVFFYPLDFTFVCPSELIAFDHRMEEFTKRGVEVIGVSIDSQ
FTHNAWRNTPVEKGGIGQVKYTLVADVKHEICKAYDVEHPEAGVAFRGSFLIDKEGMVRHQVVNDLPLGRNVDEMLRMID
ALQFHEEHGDVCPAGWEKGDKGMNASTEGVAAYLSENASSL

Sequences:

>Translated_201_residues
MSVLVGRQAPDFTAAAVLGSGEIVDSFNLTAAIKGKPAVVFFYPLDFTFVCPSELIAFDHRMEEFTKRGVEVIGVSIDSQ
FTHNAWRNTPVEKGGIGQVKYTLVADVKHEICKAYDVEHPEAGVAFRGSFLIDKEGMVRHQVVNDLPLGRNVDEMLRMID
ALQFHEEHGDVCPAGWEKGDKGMNASTEGVAAYLSENASSL
>Mature_200_residues
SVLVGRQAPDFTAAAVLGSGEIVDSFNLTAAIKGKPAVVFFYPLDFTFVCPSELIAFDHRMEEFTKRGVEVIGVSIDSQF
THNAWRNTPVEKGGIGQVKYTLVADVKHEICKAYDVEHPEAGVAFRGSFLIDKEGMVRHQVVNDLPLGRNVDEMLRMIDA
LQFHEEHGDVCPAGWEKGDKGMNASTEGVAAYLSENASSL

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32189392, Length=194, Percent_Identity=48.9690721649485, Blast_Score=199, Evalue=2e-51,
Organism=Homo sapiens, GI4505591, Length=193, Percent_Identity=47.6683937823834, Blast_Score=195, Evalue=2e-50,
Organism=Homo sapiens, GI32455266, Length=193, Percent_Identity=47.6683937823834, Blast_Score=195, Evalue=2e-50,
Organism=Homo sapiens, GI32455264, Length=193, Percent_Identity=47.6683937823834, Blast_Score=195, Evalue=2e-50,
Organism=Homo sapiens, GI5453549, Length=192, Percent_Identity=45.3125, Blast_Score=181, Evalue=5e-46,
Organism=Homo sapiens, GI32483377, Length=189, Percent_Identity=44.4444444444444, Blast_Score=171, Evalue=5e-43,
Organism=Homo sapiens, GI5802974, Length=192, Percent_Identity=43.75, Blast_Score=170, Evalue=7e-43,
Organism=Homo sapiens, GI33188454, Length=83, Percent_Identity=57.8313253012048, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI4758638, Length=199, Percent_Identity=29.1457286432161, Blast_Score=70, Evalue=9e-13,
Organism=Escherichia coli, GI1786822, Length=158, Percent_Identity=36.7088607594937, Blast_Score=115, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI32565831, Length=194, Percent_Identity=44.8453608247423, Blast_Score=179, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI193204376, Length=194, Percent_Identity=44.8453608247423, Blast_Score=179, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17554494, Length=173, Percent_Identity=47.3988439306358, Blast_Score=171, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI25153706, Length=186, Percent_Identity=27.4193548387097, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6323613, Length=194, Percent_Identity=40.7216494845361, Blast_Score=160, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6320661, Length=179, Percent_Identity=40.2234636871508, Blast_Score=146, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6319407, Length=184, Percent_Identity=29.3478260869565, Blast_Score=87, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24656348, Length=194, Percent_Identity=47.4226804123711, Blast_Score=188, Evalue=3e-48,
Organism=Drosophila melanogaster, GI17864676, Length=194, Percent_Identity=47.4226804123711, Blast_Score=188, Evalue=3e-48,
Organism=Drosophila melanogaster, GI17738015, Length=177, Percent_Identity=48.0225988700565, Blast_Score=180, Evalue=6e-46,
Organism=Drosophila melanogaster, GI17157991, Length=192, Percent_Identity=44.7916666666667, Blast_Score=174, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24641739, Length=192, Percent_Identity=44.7916666666667, Blast_Score=174, Evalue=3e-44,
Organism=Drosophila melanogaster, GI21357347, Length=191, Percent_Identity=42.9319371727749, Blast_Score=169, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24581278, Length=189, Percent_Identity=31.7460317460317, Blast_Score=95, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17975518, Length=155, Percent_Identity=32.258064516129, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24652436, Length=155, Percent_Identity=32.258064516129, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24652434, Length=155, Percent_Identity=32.258064516129, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 21990; Mature: 21859

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLVGRQAPDFTAAAVLGSGEIVDSFNLTAAIKGKPAVVFFYPLDFTFVCPSELIAFDH
CCEECCCCCCCCCEEEEECCCCEEECCCEEEEECCCCEEEEEECCCEEEECHHHHHHHHH
RMEEFTKRGVEVIGVSIDSQFTHNAWRNTPVEKGGIGQVKYTLVADVKHEICKAYDVEHP
HHHHHHHCCEEEEEEECCCCHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCC
EAGVAFRGSFLIDKEGMVRHQVVNDLPLGRNVDEMLRMIDALQFHEEHGDVCPAGWEKGD
CCCEEEECEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
KGMNASTEGVAAYLSENASSL
CCCCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SVLVGRQAPDFTAAAVLGSGEIVDSFNLTAAIKGKPAVVFFYPLDFTFVCPSELIAFDH
CEECCCCCCCCCEEEEECCCCEEECCCEEEEECCCCEEEEEECCCEEEECHHHHHHHHH
RMEEFTKRGVEVIGVSIDSQFTHNAWRNTPVEKGGIGQVKYTLVADVKHEICKAYDVEHP
HHHHHHHCCEEEEEEECCCCHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCC
EAGVAFRGSFLIDKEGMVRHQVVNDLPLGRNVDEMLRMIDALQFHEEHGDVCPAGWEKGD
CCCEEEECEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
KGMNASTEGVAAYLSENASSL
CCCCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]