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The map label for this gene is fabD [H]

Identifier: 160874873

GI number: 160874873

Start: 2106522

End: 2107448

Strand: Direct

Name: fabD [H]

Synonym: Sbal195_1758

Alternate gene names: 160874873

Gene position: 2106522-2107448 (Clockwise)

Preceding gene: 160874872

Following gene: 160874874

Centisome position: 39.39

GC content: 49.3

Gene sequence:

>927_bases
ATGGAAAATGTTGCTTTTGTATTTCCAGGCCAAGGTTCACAAGCCCTAGGCATGTTAGCCGAGCTTGCCGAATCACACGC
CGTTGTCGGGCAAACCTTTGCCGAAGCGAGTGACGTCTTAGGTTATGATTTGTGGGCATTGGTTCAGCAAGGTCCAGTTG
AAAGCTTAAATGAAACCGATAAAACCCAGCCAGCTCTATTAGCGGCGAGCGTGGCGATTTGGCGTGCCTATGTGGCTTCA
GGCAAACCTATGCCAGCCATGTTAGCGGGTCACAGCTTAGGCGAGTATTCTGCTTTAGTGTGCGCCGGAGTCATGGATTT
TAAAGACGCGATTAAGTTGGTGGAGTTACGCGGTCAACTGATGCAGCAAGCGGTTCCTGCTGGCACAGGCGCCATGTATG
CCATTATCGGTTTAGATAACGAGGGTATCGCGAATGCTTGCGCCGAAGCGGCTCAAGGCGACGTGGTGAGCCCAGTTAAC
TTCAACAGCCCTGGTCAAGTCGTTATCGCGGGTCAAAAAGACGCGGTTGAGCGTGCAGCTGCGGCGTGTAAAGCAGCGGG
CGCTAAAATGGCAGTTGCTTTACCTGTCAGCGTGCCATCACACTGCGCATTAATGAAACCAGCGGCGGATAAACTGGCCG
TGGCATTAAACGATGTACAGTTTAATGCCCCAACGATTACTGTGATTAACAACGTTGATGTGGCATCACCAACGTCTGCT
GATGACATTAAAGATGCATTAGTACGTCAGTTATATTGTCCTGTCCGCTGGAGCGAAACTGTTGAGCTAATGGCCCAAAA
AGGCATTACCCAACTGGTGGAATGTGGTCCTGGTAAAGTATTGACAGGATTAGCAAAACGAATTAATAAATCACTATCAG
CCCAAGCGGTTAATGATGTCGCTTCATTAGCAGCATTAACTGAGTAA

Upstream 100 bases:

>100_bases
CCGGTTTTGCGTGGGGCAGTGCGCTCATTCGCTTCTAAGTTCTACATGTGTTTTCCACATGATTTTTCAATAAATTAAGT
TAGCCATAGGTAATTTGAAT

Downstream 100 bases:

>100_bases
GGAGTTTGTATGAGTTTCAACCTGAATTTAACAGGCAAAGTGGCTTTGGTGACTGGTGCGAGCCGCGGTATTGGCCGTGC
GATCGCTGAGACACTGGTCG

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MENVAFVFPGQGSQALGMLAELAESHAVVGQTFAEASDVLGYDLWALVQQGPVESLNETDKTQPALLAASVAIWRAYVAS
GKPMPAMLAGHSLGEYSALVCAGVMDFKDAIKLVELRGQLMQQAVPAGTGAMYAIIGLDNEGIANACAEAAQGDVVSPVN
FNSPGQVVIAGQKDAVERAAAACKAAGAKMAVALPVSVPSHCALMKPAADKLAVALNDVQFNAPTITVINNVDVASPTSA
DDIKDALVRQLYCPVRWSETVELMAQKGITQLVECGPGKVLTGLAKRINKSLSAQAVNDVASLAALTE

Sequences:

>Translated_308_residues
MENVAFVFPGQGSQALGMLAELAESHAVVGQTFAEASDVLGYDLWALVQQGPVESLNETDKTQPALLAASVAIWRAYVAS
GKPMPAMLAGHSLGEYSALVCAGVMDFKDAIKLVELRGQLMQQAVPAGTGAMYAIIGLDNEGIANACAEAAQGDVVSPVN
FNSPGQVVIAGQKDAVERAAAACKAAGAKMAVALPVSVPSHCALMKPAADKLAVALNDVQFNAPTITVINNVDVASPTSA
DDIKDALVRQLYCPVRWSETVELMAQKGITQLVECGPGKVLTGLAKRINKSLSAQAVNDVASLAALTE
>Mature_308_residues
MENVAFVFPGQGSQALGMLAELAESHAVVGQTFAEASDVLGYDLWALVQQGPVESLNETDKTQPALLAASVAIWRAYVAS
GKPMPAMLAGHSLGEYSALVCAGVMDFKDAIKLVELRGQLMQQAVPAGTGAMYAIIGLDNEGIANACAEAAQGDVVSPVN
FNSPGQVVIAGQKDAVERAAAACKAAGAKMAVALPVSVPSHCALMKPAADKLAVALNDVQFNAPTITVINNVDVASPTSA
DDIKDALVRQLYCPVRWSETVELMAQKGITQLVECGPGKVLTGLAKRINKSLSAQAVNDVASLAALTE

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=311, Percent_Identity=33.1189710610932, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI27477045, Length=110, Percent_Identity=40.9090909090909, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1787334, Length=308, Percent_Identity=68.1818181818182, Blast_Score=404, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI71984332, Length=296, Percent_Identity=30.4054054054054, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17550940, Length=292, Percent_Identity=29.1095890410959, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24665753, Length=318, Percent_Identity=31.7610062893082, Blast_Score=136, Evalue=2e-32,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 31815; Mature: 31815

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENVAFVFPGQGSQALGMLAELAESHAVVGQTFAEASDVLGYDLWALVQQGPVESLNETD
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCC
KTQPALLAASVAIWRAYVASGKPMPAMLAGHSLGEYSALVCAGVMDFKDAIKLVELRGQL
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MQQAVPAGTGAMYAIIGLDNEGIANACAEAAQGDVVSPVNFNSPGQVVIAGQKDAVERAA
HHHHCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEECCHHHHHHHH
AACKAAGAKMAVALPVSVPSHCALMKPAADKLAVALNDVQFNAPTITVINNVDVASPTSA
HHHHHCCCCEEEEEECCCCCCHHCCCCCHHHHEEEEECEEECCCEEEEEECCCCCCCCCH
DDIKDALVRQLYCPVRWSETVELMAQKGITQLVECGPGKVLTGLAKRINKSLSAQAVNDV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ASLAALTE
HHHHHHCC
>Mature Secondary Structure
MENVAFVFPGQGSQALGMLAELAESHAVVGQTFAEASDVLGYDLWALVQQGPVESLNETD
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCC
KTQPALLAASVAIWRAYVASGKPMPAMLAGHSLGEYSALVCAGVMDFKDAIKLVELRGQL
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MQQAVPAGTGAMYAIIGLDNEGIANACAEAAQGDVVSPVNFNSPGQVVIAGQKDAVERAA
HHHHCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEECCHHHHHHHH
AACKAAGAKMAVALPVSVPSHCALMKPAADKLAVALNDVQFNAPTITVINNVDVASPTSA
HHHHHCCCCEEEEEECCCCCCHHCCCCCHHHHEEEEECEEECCCEEEEEECCCCCCCCCH
DDIKDALVRQLYCPVRWSETVELMAQKGITQLVECGPGKVLTGLAKRINKSLSAQAVNDV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ASLAALTE
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]