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The map label for this gene is phoR [H]

Identifier: 160874522

GI number: 160874522

Start: 1682323

End: 1683621

Strand: Direct

Name: phoR [H]

Synonym: Sbal195_1404

Alternate gene names: 160874522

Gene position: 1682323-1683621 (Clockwise)

Preceding gene: 160874521

Following gene: 160874523

Centisome position: 31.46

GC content: 48.19

Gene sequence:

>1299_bases
ATGTCTGACTCTTATTCAGGGTACCGGTTGTTTACGCGCTTAGCCTTATATCTACTGCTTTGCGCGCTAATAGGTTTATT
GGTAGGGAAACTTCTCTGGATACTCTTTTTCGGCATGCTAGGCCTGGTTTGCTGGCATTACCGACAATTATCACGGCTTA
ACTTTTGGTTATGGCGCGATAGAAAACTCACGCCGCCGCAGGGCAGTGGGAGTTGGGAAGGGGTGTTTAACGGTATTTAT
CGCCTCCAAGGTAAGAATCGTCGACGTGTCGGTCAATTGGCCGCATTGCTGGCGCGATTTCGCCAAGGTGCAGAAGCGTT
ACCCGATGCCGCTGTGGTGCTCGATTCAGAGCATAATATTTTATGGTGCAACAAGTTAGCGCAGCTTATTCTCGGTTTTG
TTTGGCCGCAGGATAATGGCCAGCGTATTGATAACTTGATCCGCCATCCTGATTTTTCCGCTTATATTAAATCCGCACAA
TACAAAGAGCCGCTGGAGTTACCATCGCCGGTATCGGATAGGCGTTTGCTTGAGATCCGTATCATGGCCTACGGTGATAG
GCAGCTACTATTAATTGCGCGGGATATCACTCGTATACGTCAGCTCGAGGGCATGCGTAAAGAGTTTGTCGCCAATGTGT
CACATGAATTAAAAACGCCGCTCACTGTGTTGCAGGGTTATCTCGAAATGATGCAAAGCATGGCTGAGCCCGATTCGATG
AACGTCAAACCGCTGGCCTTAATGCAGCAGCAGACGCGGCGAATGCAATCTATGGTCGAACAGCTATTAATGTTATCGCG
GATTGAAGATGCGGCCGATATCAACCTCGAACATACAGTGAACATGACGCAGCTGATGGAAGTGCTCAAGGAGGAAGCTA
AAGCGCTGGCACAAGATAGATACGAGCTGAGCTTCTATTGCGAACCAGGGCTTGATTCCCACGGTAATGAATTACAGCTA
AGAAGTGCTTGTTCAAACTTGATTTCTAACGCGATTCGTTACACTGAACCCGGCGGTAAAATCACAGTGCAGTGGCGCAG
TATGGCAACGGGAGCCATCTTTAGCGTAACGGATACGGGCGAAGGCATTGCACCTCAGCACATAGGTCGATTAACTGAAC
GTTTCTATCGGGTAGACAGTGCGCGCTCAAGGCAAACCGGTGGCAGTGGTCTAGGTCTTGCGATAGTAAAGCATGCGCTT
AACCATCATCACAGTGAGCTTAAAATCAGCAGTGAAGTGGGTAAAGGCAGTACGTTTAGCTTTGTTATTCCTTTACATCT
TATCGAGCGTAAGAAATAA

Upstream 100 bases:

>100_bases
GTTTCTCTACACGCATTTAGTGCCGAATAAGTGTTAGGCACAAGTTAGCTTTTAGGCTATCTTGTGCTCCTCTTATTTAG
CCTGATGTTTGGGTTTATCT

Downstream 100 bases:

>100_bases
ATTGCTTAAGTGAAATATTCGCAATTAATAATAAAAACAGGCCATTATGGCCTGTTTTTGTTTCTAGGTTCAGAGAGTTG
TTTATTAGTGACAGAAAAAA

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MSDSYSGYRLFTRLALYLLLCALIGLLVGKLLWILFFGMLGLVCWHYRQLSRLNFWLWRDRKLTPPQGSGSWEGVFNGIY
RLQGKNRRRVGQLAALLARFRQGAEALPDAAVVLDSEHNILWCNKLAQLILGFVWPQDNGQRIDNLIRHPDFSAYIKSAQ
YKEPLELPSPVSDRRLLEIRIMAYGDRQLLLIARDITRIRQLEGMRKEFVANVSHELKTPLTVLQGYLEMMQSMAEPDSM
NVKPLALMQQQTRRMQSMVEQLLMLSRIEDAADINLEHTVNMTQLMEVLKEEAKALAQDRYELSFYCEPGLDSHGNELQL
RSACSNLISNAIRYTEPGGKITVQWRSMATGAIFSVTDTGEGIAPQHIGRLTERFYRVDSARSRQTGGSGLGLAIVKHAL
NHHHSELKISSEVGKGSTFSFVIPLHLIERKK

Sequences:

>Translated_432_residues
MSDSYSGYRLFTRLALYLLLCALIGLLVGKLLWILFFGMLGLVCWHYRQLSRLNFWLWRDRKLTPPQGSGSWEGVFNGIY
RLQGKNRRRVGQLAALLARFRQGAEALPDAAVVLDSEHNILWCNKLAQLILGFVWPQDNGQRIDNLIRHPDFSAYIKSAQ
YKEPLELPSPVSDRRLLEIRIMAYGDRQLLLIARDITRIRQLEGMRKEFVANVSHELKTPLTVLQGYLEMMQSMAEPDSM
NVKPLALMQQQTRRMQSMVEQLLMLSRIEDAADINLEHTVNMTQLMEVLKEEAKALAQDRYELSFYCEPGLDSHGNELQL
RSACSNLISNAIRYTEPGGKITVQWRSMATGAIFSVTDTGEGIAPQHIGRLTERFYRVDSARSRQTGGSGLGLAIVKHAL
NHHHSELKISSEVGKGSTFSFVIPLHLIERKK
>Mature_431_residues
SDSYSGYRLFTRLALYLLLCALIGLLVGKLLWILFFGMLGLVCWHYRQLSRLNFWLWRDRKLTPPQGSGSWEGVFNGIYR
LQGKNRRRVGQLAALLARFRQGAEALPDAAVVLDSEHNILWCNKLAQLILGFVWPQDNGQRIDNLIRHPDFSAYIKSAQY
KEPLELPSPVSDRRLLEIRIMAYGDRQLLLIARDITRIRQLEGMRKEFVANVSHELKTPLTVLQGYLEMMQSMAEPDSMN
VKPLALMQQQTRRMQSMVEQLLMLSRIEDAADINLEHTVNMTQLMEVLKEEAKALAQDRYELSFYCEPGLDSHGNELQLR
SACSNLISNAIRYTEPGGKITVQWRSMATGAIFSVTDTGEGIAPQHIGRLTERFYRVDSARSRQTGGSGLGLAIVKHALN
HHHSELKISSEVGKGSTFSFVIPLHLIERKK

Specific function: Member of the two-component regulatory system phoR/phoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates phoB in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=409, Percent_Identity=52.8117359413203, Blast_Score=439, Evalue=1e-124,
Organism=Escherichia coli, GI1786783, Length=235, Percent_Identity=33.6170212765957, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1788393, Length=252, Percent_Identity=26.984126984127, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1790346, Length=233, Percent_Identity=31.3304721030043, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI145693157, Length=223, Percent_Identity=30.4932735426009, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1789149, Length=249, Percent_Identity=29.718875502008, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1790861, Length=314, Percent_Identity=27.0700636942675, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1789808, Length=228, Percent_Identity=29.8245614035088, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1787894, Length=241, Percent_Identity=30.2904564315353, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1790551, Length=217, Percent_Identity=29.9539170506912, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1788549, Length=351, Percent_Identity=23.3618233618234, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788713, Length=233, Percent_Identity=24.4635193133047, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI48994928, Length=384, Percent_Identity=24.7395833333333, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87082128, Length=239, Percent_Identity=27.6150627615063, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1790436, Length=251, Percent_Identity=26.6932270916335, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789403, Length=203, Percent_Identity=30.0492610837438, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788279, Length=217, Percent_Identity=24.8847926267281, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR021766
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR014310 [H]

Pfam domain/function: PF11808 DUF3329; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49167; Mature: 49036

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS50109 HIS_KIN ; PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSYSGYRLFTRLALYLLLCALIGLLVGKLLWILFFGMLGLVCWHYRQLSRLNFWLWRD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEC
RKLTPPQGSGSWEGVFNGIYRLQGKNRRRVGQLAALLARFRQGAEALPDAAVVLDSEHNI
CCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHCCCCEEEEECCCCE
LWCNKLAQLILGFVWPQDNGQRIDNLIRHPDFSAYIKSAQYKEPLELPSPVSDRRLLEIR
EHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEEE
IMAYGDRQLLLIARDITRIRQLEGMRKEFVANVSHELKTPLTVLQGYLEMMQSMAEPDSM
EEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCC
NVKPLALMQQQTRRMQSMVEQLLMLSRIEDAADINLEHTVNMTQLMEVLKEEAKALAQDR
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHCCCHHHHHHHHHHHHHHHHHCC
YELSFYCEPGLDSHGNELQLRSACSNLISNAIRYTEPGGKITVQWRSMATGAIFSVTDTG
CEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEECCC
EGIAPQHIGRLTERFYRVDSARSRQTGGSGLGLAIVKHALNHHHSELKISSEVGKGSTFS
CCCCHHHHHHHHHHHHHHHCHHCCCCCCCCHHHHHHHHHHHCCHHHEEEECCCCCCCEEE
FVIPLHLIERKK
EEEEHHHHCCCC
>Mature Secondary Structure 
SDSYSGYRLFTRLALYLLLCALIGLLVGKLLWILFFGMLGLVCWHYRQLSRLNFWLWRD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEC
RKLTPPQGSGSWEGVFNGIYRLQGKNRRRVGQLAALLARFRQGAEALPDAAVVLDSEHNI
CCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHCCCCEEEEECCCCE
LWCNKLAQLILGFVWPQDNGQRIDNLIRHPDFSAYIKSAQYKEPLELPSPVSDRRLLEIR
EHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEEE
IMAYGDRQLLLIARDITRIRQLEGMRKEFVANVSHELKTPLTVLQGYLEMMQSMAEPDSM
EEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCC
NVKPLALMQQQTRRMQSMVEQLLMLSRIEDAADINLEHTVNMTQLMEVLKEEAKALAQDR
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHCCCHHHHHHHHHHHHHHHHHCC
YELSFYCEPGLDSHGNELQLRSACSNLISNAIRYTEPGGKITVQWRSMATGAIFSVTDTG
CEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEECCC
EGIAPQHIGRLTERFYRVDSARSRQTGGSGLGLAIVKHALNHHHSELKISSEVGKGSTFS
CCCCHHHHHHHHHHHHHHHCHHCCCCCCCCHHHHHHHHHHHCCHHHEEEECCCCCCCEEE
FVIPLHLIERKK
EEEEHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2556368 [H]