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The map label for this gene is aer [H]

Identifier: 160874436

GI number: 160874436

Start: 1565764

End: 1567332

Strand: Direct

Name: aer [H]

Synonym: Sbal195_1317

Alternate gene names: 160874436

Gene position: 1565764-1567332 (Clockwise)

Preceding gene: 160874435

Following gene: 160874437

Centisome position: 29.28

GC content: 49.01

Gene sequence:

>1569_bases
ATGCATAAAAATTCTAAGAATGGTGAAACACACCTGTCAGATAATGCGATTCTACTATCCACGACGGATTTGAAGGGAAA
CATTAAATATGTGAATCAGACTTTTTCGCAGATCAGCGAGTTTAGCGCTGCTGAGTTACAAGGGAATCCCCATAACATAG
TGCGTCATCAAGATATGCCAGCGGCTGCGTTTAAGATCCTTTGGGAGCGAATTAAGCTGGGTAAACCTTGGATGGGTATC
GTTAAAAATCGCACTAAAAATGGCGGTTATTACTGGGTAAATGCCTATGTTGCCCCTGTGTATGAAGACGGTAAAATTCA
CGAATATCAATCTGTTCGCCGCCAAGCCACTCCAGAGCAGATCAAAGCCGCCGAGAGTATTTACAGCGATATTAATCAGG
GTAAGCAACCTAAAGTATTGCGCAAAGACAGGTTAGGTTTCAGTGGCAAGATACTGCTGGCCATGCTGATGTCGATTATG
ACTACGGCAATGATTGCCAGTTATTCTCCCATTGTTGCCGCGATTGCGGGGATGACGGTAGCGTGCCTAGCATGGTATTA
CCTGATGCAGCCGCTGCAAAAGCTCGTGTCTATGGCAACAAACATTATTGACGATCCTGTGGCGACGGGCGTGTATACCG
GCCGCCAAGATGAGATTGGAAAATTGGATCTTGCCTTGCGCTTTTTGATCACCGAAATCGGTGGCGTTGTTGGCCGTATG
GCGGATTCGGCCAGTGAAATCCAATCTCAGAGTGTCAGCCTTAAACAAACCATTACCAACACTTGGGAACATGCCGATAG
TCAGAGCGAGCAAACGACGCAGGCTGCAACTGCGATGGAGCAGATGAGCGCCAGTTTTGCCGAAGTGACGGGCAACATTC
ATCGCACGGCCTCTGAAATGGTGTCGAACCATGAGGCGGCGCAACGCGGTCATTCACGCTTAGAAACAGTGATAGAGGCG
ATACATCAGCTGAGTGTGCAAGTGAGCCACTTTTCCGATGTAGTTCAAACGATTGAAGAAGATAGCCGTGCTATTCATCA
AGTGCTTGAAGTGATACGTGCCATCGCTGACCAAACCAACTTGTTAGCTTTAAATGCGGCAATCGAAGCGGCGCGGGCTG
GGGATAGTGGTCGCGGTTTTGCAGTGGTGGCCGATGAGGTCAGACAATTATCGAGTCGTACTAGCCAATCCACCTCGCAA
ATCGAGTTAATCGTTAGCCGCTTTAGGGAAAGTACCCAAAGGGCGACTTCGACTATGGTGGCGGGACAAGAGCAGGTTAA
ACGTTCAGTAGGCTTAGCGCAGGAAGCCAGTGTCGCTTTTGGCGAGTTGCTTTCATCTATAACAAGAATTAACTCCTTAA
GTGATGATAATGCCGCGGCGATGACCCAGCAGACTTCTGTGGCCGCTGAAATTAGCCGTGCCATCCATGTGATCAGCGAT
TTGGCTCAACAGAGTTTAGAGCAGACGCTCGATGCGGCGGCGCGGGGCGATCAAGTGTCGCGGTTATCGACCAAGACGCA
TCATCTGTCCCAGCAGTTTTGGCAGCAGAGCGTGCAACGTAAATATTAA

Upstream 100 bases:

>100_bases
AATTTTTATGCTGCCAATGTGAGCTTTATCAATTTTGATGTACTGAGGTTTTGGCAGAATGCTCGTTATCTTTTTTACCG
AGACCTAGCCTGATAACCCT

Downstream 100 bases:

>100_bases
GCGTATTTACCTTATGTCGTATTGGATTTTGTGATTGATTTATTATTAATGCCTGTATATAAATCAATCACTTAATCGCA
TTTTTCTGGCGGTTTTATTT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 522; Mature: 522

Protein sequence:

>522_residues
MHKNSKNGETHLSDNAILLSTTDLKGNIKYVNQTFSQISEFSAAELQGNPHNIVRHQDMPAAAFKILWERIKLGKPWMGI
VKNRTKNGGYYWVNAYVAPVYEDGKIHEYQSVRRQATPEQIKAAESIYSDINQGKQPKVLRKDRLGFSGKILLAMLMSIM
TTAMIASYSPIVAAIAGMTVACLAWYYLMQPLQKLVSMATNIIDDPVATGVYTGRQDEIGKLDLALRFLITEIGGVVGRM
ADSASEIQSQSVSLKQTITNTWEHADSQSEQTTQAATAMEQMSASFAEVTGNIHRTASEMVSNHEAAQRGHSRLETVIEA
IHQLSVQVSHFSDVVQTIEEDSRAIHQVLEVIRAIADQTNLLALNAAIEAARAGDSGRGFAVVADEVRQLSSRTSQSTSQ
IELIVSRFRESTQRATSTMVAGQEQVKRSVGLAQEASVAFGELLSSITRINSLSDDNAAAMTQQTSVAAEISRAIHVISD
LAQQSLEQTLDAAARGDQVSRLSTKTHHLSQQFWQQSVQRKY

Sequences:

>Translated_522_residues
MHKNSKNGETHLSDNAILLSTTDLKGNIKYVNQTFSQISEFSAAELQGNPHNIVRHQDMPAAAFKILWERIKLGKPWMGI
VKNRTKNGGYYWVNAYVAPVYEDGKIHEYQSVRRQATPEQIKAAESIYSDINQGKQPKVLRKDRLGFSGKILLAMLMSIM
TTAMIASYSPIVAAIAGMTVACLAWYYLMQPLQKLVSMATNIIDDPVATGVYTGRQDEIGKLDLALRFLITEIGGVVGRM
ADSASEIQSQSVSLKQTITNTWEHADSQSEQTTQAATAMEQMSASFAEVTGNIHRTASEMVSNHEAAQRGHSRLETVIEA
IHQLSVQVSHFSDVVQTIEEDSRAIHQVLEVIRAIADQTNLLALNAAIEAARAGDSGRGFAVVADEVRQLSSRTSQSTSQ
IELIVSRFRESTQRATSTMVAGQEQVKRSVGLAQEASVAFGELLSSITRINSLSDDNAAAMTQQTSVAAEISRAIHVISD
LAQQSLEQTLDAAARGDQVSRLSTKTHHLSQQFWQQSVQRKY
>Mature_522_residues
MHKNSKNGETHLSDNAILLSTTDLKGNIKYVNQTFSQISEFSAAELQGNPHNIVRHQDMPAAAFKILWERIKLGKPWMGI
VKNRTKNGGYYWVNAYVAPVYEDGKIHEYQSVRRQATPEQIKAAESIYSDINQGKQPKVLRKDRLGFSGKILLAMLMSIM
TTAMIASYSPIVAAIAGMTVACLAWYYLMQPLQKLVSMATNIIDDPVATGVYTGRQDEIGKLDLALRFLITEIGGVVGRM
ADSASEIQSQSVSLKQTITNTWEHADSQSEQTTQAATAMEQMSASFAEVTGNIHRTASEMVSNHEAAQRGHSRLETVIEA
IHQLSVQVSHFSDVVQTIEEDSRAIHQVLEVIRAIADQTNLLALNAAIEAARAGDSGRGFAVVADEVRQLSSRTSQSTSQ
IELIVSRFRESTQRATSTMVAGQEQVKRSVGLAQEASVAFGELLSSITRINSLSDDNAAAMTQQTSVAAEISRAIHVISD
LAQQSLEQTLDAAARGDQVSRLSTKTHHLSQQFWQQSVQRKY

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=502, Percent_Identity=32.0717131474104, Blast_Score=234, Evalue=8e-63,
Organism=Escherichia coli, GI2367378, Length=332, Percent_Identity=27.1084337349398, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1788194, Length=344, Percent_Identity=29.6511627906977, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787690, Length=410, Percent_Identity=28.5365853658537, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788195, Length=305, Percent_Identity=25.5737704918033, Blast_Score=99, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 57350; Mature: 57350

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKNSKNGETHLSDNAILLSTTDLKGNIKYVNQTFSQISEFSAAELQGNPHNIVRHQDMP
CCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCC
AAAFKILWERIKLGKPWMGIVKNRTKNGGYYWVNAYVAPVYEDGKIHEYQSVRRQATPEQ
HHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEEEEEEEEECCCCHHHHHHHHHHCCHHH
IKAAESIYSDINQGKQPKVLRKDRLGFSGKILLAMLMSIMTTAMIASYSPIVAAIAGMTV
HHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ACLAWYYLMQPLQKLVSMATNIIDDPVATGVYTGRQDEIGKLDLALRFLITEIGGVVGRM
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ADSASEIQSQSVSLKQTITNTWEHADSQSEQTTQAATAMEQMSASFAEVTGNIHRTASEM
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSNHEAAQRGHSRLETVIEAIHQLSVQVSHFSDVVQTIEEDSRAIHQVLEVIRAIADQTN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LLALNAAIEAARAGDSGRGFAVVADEVRQLSSRTSQSTSQIELIVSRFRESTQRATSTMV
EEEHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
AGQEQVKRSVGLAQEASVAFGELLSSITRINSLSDDNAAAMTQQTSVAAEISRAIHVISD
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LAQQSLEQTLDAAARGDQVSRLSTKTHHLSQQFWQQSVQRKY
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHKNSKNGETHLSDNAILLSTTDLKGNIKYVNQTFSQISEFSAAELQGNPHNIVRHQDMP
CCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCC
AAAFKILWERIKLGKPWMGIVKNRTKNGGYYWVNAYVAPVYEDGKIHEYQSVRRQATPEQ
HHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEEEEEEEEECCCCHHHHHHHHHHCCHHH
IKAAESIYSDINQGKQPKVLRKDRLGFSGKILLAMLMSIMTTAMIASYSPIVAAIAGMTV
HHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ACLAWYYLMQPLQKLVSMATNIIDDPVATGVYTGRQDEIGKLDLALRFLITEIGGVVGRM
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ADSASEIQSQSVSLKQTITNTWEHADSQSEQTTQAATAMEQMSASFAEVTGNIHRTASEM
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSNHEAAQRGHSRLETVIEAIHQLSVQVSHFSDVVQTIEEDSRAIHQVLEVIRAIADQTN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LLALNAAIEAARAGDSGRGFAVVADEVRQLSSRTSQSTSQIELIVSRFRESTQRATSTMV
EEEHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
AGQEQVKRSVGLAQEASVAFGELLSSITRINSLSDDNAAAMTQQTSVAAEISRAIHVISD
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LAQQSLEQTLDAAARGDQVSRLSTKTHHLSQQFWQQSVQRKY
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]