| Definition | Shewanella baltica OS195 chromosome, complete genome. |
|---|---|
| Accession | NC_009997 |
| Length | 5,347,283 |
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The map label for this gene is thrA [H]
Identifier: 160874423
GI number: 160874423
Start: 1543486
End: 1545954
Strand: Direct
Name: thrA [H]
Synonym: Sbal195_1304
Alternate gene names: 160874423
Gene position: 1543486-1545954 (Clockwise)
Preceding gene: 160874420
Following gene: 160874424
Centisome position: 28.86
GC content: 49.13
Gene sequence:
>2469_bases ATGAAAGTAATGAAATTTGGTGGTACCTCGCTTGCAAATTGGCAGCGATTCTCGATGGCAGCGGATATCGTTGCTCAGTC ATCTAAGCTTGAACCCATAGCCACTGTGCTATCGGCCCCTGCAACTGTGACGAATGCTTTATTAGAAATGGTCGACGTAG CCGTTAAAGGTGAAGATTATTTACCTGTGCTGCAGCACGTTGAGCGGGTATTTACTTCGCTGTACCAAGACGCCGTTAAC TCAGTGTTGTCGAGTGAGCAAAGCGAACAGCTTTTTTCTGGACTTAATGCCCAGCTGGTGATCTGGCAGGATAGATTACG TGGTATCGGATTACTGCAAGAATGTCCCGATGGTATCCGCGCCGAAATCGTGGTTGCAGGTGAGCGTTTATCTGCAGCCT TGATGGAACAAGTGATGATTTCTAAGGGGATCACTTCGGCTCAGCTCGACCCACGCGCCTTATTTTTAGGTCGTGGTCGT CCGTTAGAATCTGTCGTTGATATCGCTGTGAGTAAGCCAAGGTTTCGCGCGTTGGCGCTAGGTGAAAAACGCGTATGGGT GATGCCGGGATTCACCGCCGCCGATGAACAGGGCAAAGTGGTGACGTTAGGCCGTAATGGTTCTGACTATTCTGCTGCCG TGCTCGCCGCCTGTTTGGATGCTTCGAGCTGCGAAATCTGGACCGATGTTGACGGTGTTTATAATACCGACCCACGTGTG GTTGCCGATGCTAAGTTGTTGTCACAACTGAGCTATCAAGAGGCAATGGAGCTCTCCTATTTTGGTGCTAAGGTGTTGCA TCCTAAGACTATTGCACCTATCGCCCAGTTCCATATTCCCTGTTATATCAAAAACAGTTTTAACCCTGATGCGCCCGGTA CTCTGGTATCAAACCAAGCCGATGAAACTGGCTTACAGGTTAAAGCTATCTCCAATTTAGATAACCAGACCATGTTCGAT ATTTCAGGCCCAGGCATGAAAGGTATGGTTGGCATGGCGAGCCGTACTTTAGCGGCGATTTCCCGCAGCGGCGTGTCTGT GTCTTTAATCACCCAAAGTTCTTCTGAATACAGCATTAGCTTCTGTGTGGCCACATCTGATTCGGCCAAAGTGAAATGGG CTTTAGAGCAAGAGTTTGAATTAGAAATAAAAAGTGATTTGCTTGAGCCTATCGCTATGCGCCATGAGCTGGCCATTGTG TCCTTGATTGGTGATGGAATGCGCACCCACAAAGGGGTTGCGGCGCGTTTCTTCCAAGCGTTAGCGCAGGCTAGTGTGAA CATTATCGCCATCGCCCAAGGTTCGTCCGAGCGCTCGATTTCGACTGTGATCGAGCAGCGTAAGACTAAGCATGCGGTGG CGGCGTGTCATCAAGGCTTTTTCGATGTGCAGCAATATTTAGATGTGTTTTTAGTGGGATGCGGCAACGTGGGTGCTGGT CTGCTCGAGCAGATAAAACAACAGTCCGCCATGCTCAAAGAGCAGCACATCAGTATCCGTGTTTGCGGCATAGTGAATTC GAACAAGATGTTACTCGACAGTGCGGGCATCGATTTAAGCAACTGGTCTAGCTTGCTTGCCGATAGTCAGCAAGCTTGTG ATATCCCAGCGTTACTCGCATGGGCGAAAGAGCAACAATTACTAAACCCTGTGCTGGTGGATTGTACTTCGAGCGAGCAA GTGTCGGATCTGTATTTGGATGTGATGAACTCAGGTTTGCATGTGGTCACGCCGAACAAAAAGTCGAACACTCGCGATTA TGCTTATTACCAAGCACTTCGCCAAACAGCCTTAAAACAGCGTCGCCAATTTTTATACGAAACCACAGTCGGCGCGGGTT TACCTGTTATCGATAACCTGAAAAAACTATTATTTGCGGGCGATAAGCTGCATAAGTTTAACGGTATTTTATCGGGCTCT TTATCCTTTATCTTCGGCATGCTCGATGAAGGCATGACTCTTTCTGAAGCGACTGGTCTGGCGCGGGAAAAATGTTTTAC TGAGCCCGATCCCCGTGATGATTTGAGTGGTATGGATGTGGCGCGTAAGGTGCTCATTCTTGCCCGTGAAGTGGGACTAA AGCTAGAACTCAGTGACGTGCAGGTTGAATCTGTATTGCCAGCGGAGTTTGATGATTCAGGCGATGTTGAGAGCTTTATG GCGCGTTTGCCGCAGGTTGATGCGGCGATTGCCGCTAAAGTGGCGCAGGCCAAAGCCCAAAGTAAAGTGCTGCGTTATGT GGGACAAATTGAAGACGGTGTGTGCCGAGTGCGTATCGCCGAAGTCGATGCACAGGATCCCCTTTATAGTGTTAAAGGCG GTGAAAATGCCTTGGCATTCTACAGCCGTTATTATCAGCCCATTCCGTTTGTGCTGCGCGGTTATGGCGCGGGAACGGAA GTGACTGCCGCTGGCGCTTTTGCCGATGTATTAAGAACCTTGAATTGGACTCGTGAGGTGAGTGTATGA
Upstream 100 bases:
>100_bases ACCCTAAAGAATTTTAACAATGAGCCCGCTTCCCACAAAGAAGCGGGCTTTTTTGTTTCTAGCTCTTATTTCTAAGTCGG GCGCGGTACAGGAGAACAAG
Downstream 100 bases:
>100_bases GTTTGACCGTTTACGCTCCAGCCTCTATGGGTAACGTGGGAGTCGGATTTGATTTACTGGGCGCCGCTTTGGCGCCTATC GATGGCAGTTTACTCGGCGA
Product: bifunctional aspartokinase I/homoserine dehydrogenase I
Products: NA
Alternate protein names: Aspartokinase I/homoserine dehydrogenase I; AKI-HDI; Aspartokinase; Homoserine dehydrogenase [H]
Number of amino acids: Translated: 822; Mature: 822
Protein sequence:
>822_residues MKVMKFGGTSLANWQRFSMAADIVAQSSKLEPIATVLSAPATVTNALLEMVDVAVKGEDYLPVLQHVERVFTSLYQDAVN SVLSSEQSEQLFSGLNAQLVIWQDRLRGIGLLQECPDGIRAEIVVAGERLSAALMEQVMISKGITSAQLDPRALFLGRGR PLESVVDIAVSKPRFRALALGEKRVWVMPGFTAADEQGKVVTLGRNGSDYSAAVLAACLDASSCEIWTDVDGVYNTDPRV VADAKLLSQLSYQEAMELSYFGAKVLHPKTIAPIAQFHIPCYIKNSFNPDAPGTLVSNQADETGLQVKAISNLDNQTMFD ISGPGMKGMVGMASRTLAAISRSGVSVSLITQSSSEYSISFCVATSDSAKVKWALEQEFELEIKSDLLEPIAMRHELAIV SLIGDGMRTHKGVAARFFQALAQASVNIIAIAQGSSERSISTVIEQRKTKHAVAACHQGFFDVQQYLDVFLVGCGNVGAG LLEQIKQQSAMLKEQHISIRVCGIVNSNKMLLDSAGIDLSNWSSLLADSQQACDIPALLAWAKEQQLLNPVLVDCTSSEQ VSDLYLDVMNSGLHVVTPNKKSNTRDYAYYQALRQTALKQRRQFLYETTVGAGLPVIDNLKKLLFAGDKLHKFNGILSGS LSFIFGMLDEGMTLSEATGLAREKCFTEPDPRDDLSGMDVARKVLILAREVGLKLELSDVQVESVLPAEFDDSGDVESFM ARLPQVDAAIAAKVAQAKAQSKVLRYVGQIEDGVCRVRIAEVDAQDPLYSVKGGENALAFYSRYYQPIPFVLRGYGAGTE VTAAGAFADVLRTLNWTREVSV
Sequences:
>Translated_822_residues MKVMKFGGTSLANWQRFSMAADIVAQSSKLEPIATVLSAPATVTNALLEMVDVAVKGEDYLPVLQHVERVFTSLYQDAVN SVLSSEQSEQLFSGLNAQLVIWQDRLRGIGLLQECPDGIRAEIVVAGERLSAALMEQVMISKGITSAQLDPRALFLGRGR PLESVVDIAVSKPRFRALALGEKRVWVMPGFTAADEQGKVVTLGRNGSDYSAAVLAACLDASSCEIWTDVDGVYNTDPRV VADAKLLSQLSYQEAMELSYFGAKVLHPKTIAPIAQFHIPCYIKNSFNPDAPGTLVSNQADETGLQVKAISNLDNQTMFD ISGPGMKGMVGMASRTLAAISRSGVSVSLITQSSSEYSISFCVATSDSAKVKWALEQEFELEIKSDLLEPIAMRHELAIV SLIGDGMRTHKGVAARFFQALAQASVNIIAIAQGSSERSISTVIEQRKTKHAVAACHQGFFDVQQYLDVFLVGCGNVGAG LLEQIKQQSAMLKEQHISIRVCGIVNSNKMLLDSAGIDLSNWSSLLADSQQACDIPALLAWAKEQQLLNPVLVDCTSSEQ VSDLYLDVMNSGLHVVTPNKKSNTRDYAYYQALRQTALKQRRQFLYETTVGAGLPVIDNLKKLLFAGDKLHKFNGILSGS LSFIFGMLDEGMTLSEATGLAREKCFTEPDPRDDLSGMDVARKVLILAREVGLKLELSDVQVESVLPAEFDDSGDVESFM ARLPQVDAAIAAKVAQAKAQSKVLRYVGQIEDGVCRVRIAEVDAQDPLYSVKGGENALAFYSRYYQPIPFVLRGYGAGTE VTAAGAFADVLRTLNWTREVSV >Mature_822_residues MKVMKFGGTSLANWQRFSMAADIVAQSSKLEPIATVLSAPATVTNALLEMVDVAVKGEDYLPVLQHVERVFTSLYQDAVN SVLSSEQSEQLFSGLNAQLVIWQDRLRGIGLLQECPDGIRAEIVVAGERLSAALMEQVMISKGITSAQLDPRALFLGRGR PLESVVDIAVSKPRFRALALGEKRVWVMPGFTAADEQGKVVTLGRNGSDYSAAVLAACLDASSCEIWTDVDGVYNTDPRV VADAKLLSQLSYQEAMELSYFGAKVLHPKTIAPIAQFHIPCYIKNSFNPDAPGTLVSNQADETGLQVKAISNLDNQTMFD ISGPGMKGMVGMASRTLAAISRSGVSVSLITQSSSEYSISFCVATSDSAKVKWALEQEFELEIKSDLLEPIAMRHELAIV SLIGDGMRTHKGVAARFFQALAQASVNIIAIAQGSSERSISTVIEQRKTKHAVAACHQGFFDVQQYLDVFLVGCGNVGAG LLEQIKQQSAMLKEQHISIRVCGIVNSNKMLLDSAGIDLSNWSSLLADSQQACDIPALLAWAKEQQLLNPVLVDCTSSEQ VSDLYLDVMNSGLHVVTPNKKSNTRDYAYYQALRQTALKQRRQFLYETTVGAGLPVIDNLKKLLFAGDKLHKFNGILSGS LSFIFGMLDEGMTLSEATGLAREKCFTEPDPRDDLSGMDVARKVLILAREVGLKLELSDVQVESVLPAEFDDSGDVESFM ARLPQVDAAIAAKVAQAKAQSKVLRYVGQIEDGVCRVRIAEVDAQDPLYSVKGGENALAFYSRYYQPIPFVLRGYGAGTE VTAAGAFADVLRTLNWTREVSV
Specific function: Catalyzes 2 nonconsecutive reactions in the common biosynthetic pathway leading from Asp to diaminopimelate and Lys, to Met, and to Thr and Ile. [C]
COG id: COG0527
COG function: function code E; Aspartokinases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 ACT domains [H]
Homologues:
Organism=Escherichia coli, GI1786183, Length=821, Percent_Identity=57.3690621193666, Blast_Score=940, Evalue=0.0, Organism=Escherichia coli, GI1790376, Length=817, Percent_Identity=31.0893512851897, Blast_Score=361, Evalue=1e-100, Organism=Escherichia coli, GI1790455, Length=471, Percent_Identity=30.5732484076433, Blast_Score=170, Evalue=4e-43, Organism=Saccharomyces cerevisiae, GI6322599, Length=338, Percent_Identity=31.0650887573964, Blast_Score=162, Evalue=3e-40, Organism=Saccharomyces cerevisiae, GI6320893, Length=505, Percent_Identity=26.1386138613861, Blast_Score=142, Evalue=2e-34,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002912 - InterPro: IPR001048 - InterPro: IPR005106 - InterPro: IPR001341 - InterPro: IPR018042 - InterPro: IPR011147 - InterPro: IPR001342 - InterPro: IPR019811 - InterPro: IPR016040 [H]
Pfam domain/function: PF00696 AA_kinase; PF01842 ACT; PF00742 Homoserine_dh; PF03447 NAD_binding_3 [H]
EC number: =2.7.2.4; =1.1.1.3 [H]
Molecular weight: Translated: 89200; Mature: 89200
Theoretical pI: Translated: 5.07; Mature: 5.07
Prosite motif: PS00324 ASPARTOKINASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.5 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 4.0 %Cys+Met (Translated Protein) 1.5 %Cys (Mature Protein) 2.6 %Met (Mature Protein) 4.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKVMKFGGTSLANWQRFSMAADIVAQSSKLEPIATVLSAPATVTNALLEMVDVAVKGEDY CCEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCC LPVLQHVERVFTSLYQDAVNSVLSSEQSEQLFSGLNAQLVIWQDRLRGIGLLQECPDGIR HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEEEHHHCCCCHHHHCCCCCE AEIVVAGERLSAALMEQVMISKGITSAQLDPRALFLGRGRPLESVVDIAVSKPRFRALAL EEEEEECHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCCCEEEEEE GEKRVWVMPGFTAADEQGKVVTLGRNGSDYSAAVLAACLDASSCEIWTDVDGVYNTDPRV CCCEEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCE VADAKLLSQLSYQEAMELSYFGAKVLHPKTIAPIAQFHIPCYIKNSFNPDAPGTLVSNQA EHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHCCCEEEECCCCCCCCCCEECCCC DETGLQVKAISNLDNQTMFDISGPGMKGMVGMASRTLAAISRSGVSVSLITQSSSEYSIS CCCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEE FCVATSDSAKVKWALEQEFELEIKSDLLEPIAMRHELAIVSLIGDGMRTHKGVAARFFQA EEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH LAQASVNIIAIAQGSSERSISTVIEQRKTKHAVAACHQGFFDVQQYLDVFLVGCGNVGAG HHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHH LLEQIKQQSAMLKEQHISIRVCGIVNSNKMLLDSAGIDLSNWSSLLADSQQACDIPALLA HHHHHHHHHHHHHHHCCEEEEEEEECCCEEEEEECCCCHHHHHHHHHCCHHHCCCHHHHH WAKEQQLLNPVLVDCTSSEQVSDLYLDVMNSGLHVVTPNKKSNTRDYAYYQALRQTALKQ HHHHHHHCCCCEEECCCCHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHH RRQFLYETTVGAGLPVIDNLKKLLFAGDKLHKFNGILSGSLSFIFGMLDEGMTLSEATGL HHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH AREKCFTEPDPRDDLSGMDVARKVLILAREVGLKLELSDVQVESVLPAEFDDSGDVESFM HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCEEEECCCCCCCCCCCCHHHHH ARLPQVDAAIAAKVAQAKAQSKVLRYVGQIEDGVCRVRIAEVDAQDPLYSVKGGENALAF HHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCEEECCCCHHHHH YSRYYQPIPFVLRGYGAGTEVTAAGAFADVLRTLNWTREVSV HHHHCCCCCHHHCCCCCCCCEEHHHHHHHHHHHHCCHHCCCC >Mature Secondary Structure MKVMKFGGTSLANWQRFSMAADIVAQSSKLEPIATVLSAPATVTNALLEMVDVAVKGEDY CCEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCC LPVLQHVERVFTSLYQDAVNSVLSSEQSEQLFSGLNAQLVIWQDRLRGIGLLQECPDGIR HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEEEHHHCCCCHHHHCCCCCE AEIVVAGERLSAALMEQVMISKGITSAQLDPRALFLGRGRPLESVVDIAVSKPRFRALAL EEEEEECHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCCCEEEEEE GEKRVWVMPGFTAADEQGKVVTLGRNGSDYSAAVLAACLDASSCEIWTDVDGVYNTDPRV CCCEEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCE VADAKLLSQLSYQEAMELSYFGAKVLHPKTIAPIAQFHIPCYIKNSFNPDAPGTLVSNQA EHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHCCCEEEECCCCCCCCCCEECCCC DETGLQVKAISNLDNQTMFDISGPGMKGMVGMASRTLAAISRSGVSVSLITQSSSEYSIS CCCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEE FCVATSDSAKVKWALEQEFELEIKSDLLEPIAMRHELAIVSLIGDGMRTHKGVAARFFQA EEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH LAQASVNIIAIAQGSSERSISTVIEQRKTKHAVAACHQGFFDVQQYLDVFLVGCGNVGAG HHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHH LLEQIKQQSAMLKEQHISIRVCGIVNSNKMLLDSAGIDLSNWSSLLADSQQACDIPALLA HHHHHHHHHHHHHHHCCEEEEEEEECCCEEEEEECCCCHHHHHHHHHCCHHHCCCHHHHH WAKEQQLLNPVLVDCTSSEQVSDLYLDVMNSGLHVVTPNKKSNTRDYAYYQALRQTALKQ HHHHHHHCCCCEEECCCCHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHH RRQFLYETTVGAGLPVIDNLKKLLFAGDKLHKFNGILSGSLSFIFGMLDEGMTLSEATGL HHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH AREKCFTEPDPRDDLSGMDVARKVLILAREVGLKLELSDVQVESVLPAEFDDSGDVESFM HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCEEEECCCCCCCCCCCCHHHHH ARLPQVDAAIAAKVAQAKAQSKVLRYVGQIEDGVCRVRIAEVDAQDPLYSVKGGENALAF HHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCEEECCCCHHHHH YSRYYQPIPFVLRGYGAGTEVTAAGAFADVLRTLNWTREVSV HHHHCCCCCHHHCCCCCCCCEEHHHHHHHHHHHHCCHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 7003595; 1630901; 7610040; 9278503; 6277952; 2410621; 387092; 6298218; 390305 [H]