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The map label for this gene is yjcE [H]

Identifier: 160874415

GI number: 160874415

Start: 1533877

End: 1535181

Strand: Direct

Name: yjcE [H]

Synonym: Sbal195_1296

Alternate gene names: 160874415

Gene position: 1533877-1535181 (Clockwise)

Preceding gene: 160874414

Following gene: 160874418

Centisome position: 28.69

GC content: 44.37

Gene sequence:

>1305_bases
ATGTCCAGTTACCAAATTCTGTGTATCCTCTGCGCCTTGGCGCTAGTCACTTCAGTTGTCTCTTCACGCGTCCATAAATT
GCAGGAAACTGTGGCCATTACGGCTATCGCCCTAGGTATGAGTTTGTTATTGCTCCTAGGGGGAAAGGCCTTAGGCGGAC
ATGTTTATTTGTATTTTGTCTCAGGCTTAGAGAAGCTCGATTTTCAAGCCTTGCTGCTCAATGGCATGTTAGGTTTTTTA
CTCTTTGCCGGCGCATTGCAGATCCGTTTAAAAATACTAAGGCATCAGAAGTGGGAGATTTTAATTCTCGCCTTTGTCAG
CACTTTATTATCGACCTTTATCATAGGTGGACTGTTATTTTGGGTCGCACCTATGTTGGGTCTACCGCTACAACTAAGCC
ACTGCTTGCTGTTTGGCGCCTTGATTTCTCCCACCGATCCCATCGCCGTTTTGGCTATTTTAAAGAAAATGGGTGCACCG
GAAGATATTGCTATCCAAGTGGAGGGTGAGTCTTTATTTAACGATGGTATAGGGTTAGTGATTTTTGTGGCGATATCGCA
AGTTGCTTTTTCCACTGAACCACTAACATTTATCCATGTCTCTGAGTTATTTATTCGTGAAGCGGTAGGTGGGGTTATTT
ATGGCGGCATACTTGGCTTTTTATTGCATCATTTTTTCCGCTACTGTGAGGAAGAAACGCAATTGATGCTGGTTACACTG
TTGATCCCAACCGCGGGTTATGTGATGGCGGAAGTGTTTGGAGTTTCTGGGCCTTTAGCTATGGTGAGTGCTGGTATCAT
CATAGGTAATTTCAGTGTGCCTAAATTTTTTGCTCGCAACGAGCGAGTGAAGTTACTGACATTTTGGTCGCTGATTGAAT
CCTTCTTCAATGCTTTACTCTTCCTACTGCTCGGCTTACTGCTTTTGTTAGTTACTTTTAAAGCACCATTGTGGTGGTTT
ATGTTTGTGGCGATTCCATTGGTATTATTGGCGCGTGCCGTGAGCGTGTTATTACCTTATTTGGGCTTTAGGTTGTTTAA
GTCTTACAACCCCTATGCAGAGACGATTCTGATTTGGGGTGGTTTAAGGGGAGGATTAGCACTCGCGATGGCGATGAGTT
TACCTGAGGGGATTGTCATAGATGCTATTGGTGGTGTGGAGCTACGGGAACTATTGTTAGTAATGACCTATGCCGTCATC
GTATTCTCTATTCTAGTACAAGGTTCGACTATGACAGGGCTTATTCGCAGGAGTAATGCTGTTACCGAACCATCGAGGGC
TGTCGGCGCTTCTGAAAAAGCATAA

Upstream 100 bases:

>100_bases
TTTTGCCACAGGATCATTAAAGGGTGGTTAAGTCTATTGGATGGTTTAGAAATCTAAACTTGTGCTAGAGTCTCTAAATT
GATGATTTTTAGAGGCTCGT

Downstream 100 bases:

>100_bases
AGGATGATTGCGCTACGATAGTAAACAATATTAAGCCTGTTAGTCATCACGCTGACTAGCAGGCTTATTTCAGTCAATCA
GGGATAAAATAAGTGCCTTT

Product: sodium/hydrogen exchanger

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MSSYQILCILCALALVTSVVSSRVHKLQETVAITAIALGMSLLLLLGGKALGGHVYLYFVSGLEKLDFQALLLNGMLGFL
LFAGALQIRLKILRHQKWEILILAFVSTLLSTFIIGGLLFWVAPMLGLPLQLSHCLLFGALISPTDPIAVLAILKKMGAP
EDIAIQVEGESLFNDGIGLVIFVAISQVAFSTEPLTFIHVSELFIREAVGGVIYGGILGFLLHHFFRYCEEETQLMLVTL
LIPTAGYVMAEVFGVSGPLAMVSAGIIIGNFSVPKFFARNERVKLLTFWSLIESFFNALLFLLLGLLLLLVTFKAPLWWF
MFVAIPLVLLARAVSVLLPYLGFRLFKSYNPYAETILIWGGLRGGLALAMAMSLPEGIVIDAIGGVELRELLLVMTYAVI
VFSILVQGSTMTGLIRRSNAVTEPSRAVGASEKA

Sequences:

>Translated_434_residues
MSSYQILCILCALALVTSVVSSRVHKLQETVAITAIALGMSLLLLLGGKALGGHVYLYFVSGLEKLDFQALLLNGMLGFL
LFAGALQIRLKILRHQKWEILILAFVSTLLSTFIIGGLLFWVAPMLGLPLQLSHCLLFGALISPTDPIAVLAILKKMGAP
EDIAIQVEGESLFNDGIGLVIFVAISQVAFSTEPLTFIHVSELFIREAVGGVIYGGILGFLLHHFFRYCEEETQLMLVTL
LIPTAGYVMAEVFGVSGPLAMVSAGIIIGNFSVPKFFARNERVKLLTFWSLIESFFNALLFLLLGLLLLLVTFKAPLWWF
MFVAIPLVLLARAVSVLLPYLGFRLFKSYNPYAETILIWGGLRGGLALAMAMSLPEGIVIDAIGGVELRELLLVMTYAVI
VFSILVQGSTMTGLIRRSNAVTEPSRAVGASEKA
>Mature_433_residues
SSYQILCILCALALVTSVVSSRVHKLQETVAITAIALGMSLLLLLGGKALGGHVYLYFVSGLEKLDFQALLLNGMLGFLL
FAGALQIRLKILRHQKWEILILAFVSTLLSTFIIGGLLFWVAPMLGLPLQLSHCLLFGALISPTDPIAVLAILKKMGAPE
DIAIQVEGESLFNDGIGLVIFVAISQVAFSTEPLTFIHVSELFIREAVGGVIYGGILGFLLHHFFRYCEEETQLMLVTLL
IPTAGYVMAEVFGVSGPLAMVSAGIIIGNFSVPKFFARNERVKLLTFWSLIESFFNALLFLLLGLLLLLVTFKAPLWWFM
FVAIPLVLLARAVSVLLPYLGFRLFKSYNPYAETILIWGGLRGGLALAMAMSLPEGIVIDAIGGVELRELLLVMTYAVIV
FSILVQGSTMTGLIRRSNAVTEPSRAVGASEKA

Specific function: Unknown

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Homo sapiens, GI148727259, Length=292, Percent_Identity=24.6575342465753, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI27734935, Length=378, Percent_Identity=23.015873015873, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI15529998, Length=344, Percent_Identity=26.453488372093, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI14211919, Length=449, Percent_Identity=24.2761692650334, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI27777632, Length=341, Percent_Identity=28.1524926686217, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI294997330, Length=380, Percent_Identity=24.4736842105263, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI110227626, Length=380, Percent_Identity=24.4736842105263, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI5454070, Length=362, Percent_Identity=25.1381215469613, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI41872703, Length=335, Percent_Identity=25.3731343283582, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI194239733, Length=335, Percent_Identity=25.9701492537313, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1790501, Length=200, Percent_Identity=35.5, Blast_Score=93, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71999819, Length=329, Percent_Identity=25.8358662613982, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71999817, Length=329, Percent_Identity=25.8358662613982, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71980847, Length=334, Percent_Identity=27.5449101796407, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71999821, Length=329, Percent_Identity=25.8358662613982, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71987535, Length=350, Percent_Identity=26, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71987537, Length=350, Percent_Identity=26, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71990924, Length=328, Percent_Identity=27.4390243902439, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71990932, Length=328, Percent_Identity=27.4390243902439, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71992107, Length=354, Percent_Identity=21.1864406779661, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71992101, Length=354, Percent_Identity=21.1864406779661, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI25147678, Length=315, Percent_Identity=23.8095238095238, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI25150332, Length=331, Percent_Identity=23.5649546827795, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI221510740, Length=351, Percent_Identity=27.0655270655271, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI221510734, Length=350, Percent_Identity=26.8571428571429, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI221510738, Length=350, Percent_Identity=26.8571428571429, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI281360447, Length=370, Percent_Identity=28.6486486486486, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221510732, Length=341, Percent_Identity=26.9794721407625, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI221510736, Length=341, Percent_Identity=26.9794721407625, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24585580, Length=341, Percent_Identity=26.9794721407625, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24585578, Length=341, Percent_Identity=26.9794721407625, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI221473212, Length=367, Percent_Identity=23.7057220708447, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221473222, Length=367, Percent_Identity=23.7057220708447, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221473215, Length=367, Percent_Identity=23.7057220708447, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281364513, Length=367, Percent_Identity=23.7057220708447, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR004705 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 47199; Mature: 47067

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSYQILCILCALALVTSVVSSRVHKLQETVAITAIALGMSLLLLLGGKALGGHVYLYFV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEH
SGLEKLDFQALLLNGMLGFLLFAGALQIRLKILRHQKWEILILAFVSTLLSTFIIGGLLF
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
WVAPMLGLPLQLSHCLLFGALISPTDPIAVLAILKKMGAPEDIAIQVEGESLFNDGIGLV
HHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEEECCHHHHCCHHHH
IFVAISQVAFSTEPLTFIHVSELFIREAVGGVIYGGILGFLLHHFFRYCEEETQLMLVTL
HHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
LIPTAGYVMAEVFGVSGPLAMVSAGIIIGNFSVPKFFARNERVKLLTFWSLIESFFNALL
HHHCCHHHHHHHHCCCCCHHHHHCCCEEECCCCCHHHHCCCCCHHHHHHHHHHHHHHHHH
FLLLGLLLLLVTFKAPLWWFMFVAIPLVLLARAVSVLLPYLGFRLFKSYNPYAETILIWG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEC
GLRGGLALAMAMSLPEGIVIDAIGGVELRELLLVMTYAVIVFSILVQGSTMTGLIRRSNA
CCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
VTEPSRAVGASEKA
CCCCHHHCCCCCCC
>Mature Secondary Structure 
SSYQILCILCALALVTSVVSSRVHKLQETVAITAIALGMSLLLLLGGKALGGHVYLYFV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEH
SGLEKLDFQALLLNGMLGFLLFAGALQIRLKILRHQKWEILILAFVSTLLSTFIIGGLLF
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
WVAPMLGLPLQLSHCLLFGALISPTDPIAVLAILKKMGAPEDIAIQVEGESLFNDGIGLV
HHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEEECCHHHHCCHHHH
IFVAISQVAFSTEPLTFIHVSELFIREAVGGVIYGGILGFLLHHFFRYCEEETQLMLVTL
HHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
LIPTAGYVMAEVFGVSGPLAMVSAGIIIGNFSVPKFFARNERVKLLTFWSLIESFFNALL
HHHCCHHHHHHHHCCCCCHHHHHCCCEEECCCCCHHHHCCCCCHHHHHHHHHHHHHHHHH
FLLLGLLLLLVTFKAPLWWFMFVAIPLVLLARAVSVLLPYLGFRLFKSYNPYAETILIWG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEC
GLRGGLALAMAMSLPEGIVIDAIGGVELRELLLVMTYAVIVFSILVQGSTMTGLIRRSNA
CCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
VTEPSRAVGASEKA
CCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]