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The map label for this gene is nhaR [H]

Identifier: 160874387

GI number: 160874387

Start: 1507895

End: 1508830

Strand: Direct

Name: nhaR [H]

Synonym: Sbal195_1268

Alternate gene names: 160874387

Gene position: 1507895-1508830 (Clockwise)

Preceding gene: 160874386

Following gene: 160874388

Centisome position: 28.2

GC content: 46.37

Gene sequence:

>936_bases
ATGAGGGACGATTCACAACGGATGAGCATGCTGCACTTGAATTACAACCACCTGTATTATTTTTGGATGATTAAGAAAAA
GGGCTCGGTTGCTAAGGCTGCCGAAGCCCTCTGTTTAACGCCGCAAACGATAACGGGGCAAATCCGTGCCCTAGAAGACA
GGTTGAATGGCAGTTTATTCAAGCGAGTAGGGCGGACACTGGAAGCTACTGAGTTAGGTGAGTTGGTATTTCGCTACGCA
GATAAGATGTTTAGTCTTAGCTATGAAATGCTCGATTTACTTAACTATCAAAAAGATGATGCCATGCTTTTTGAAGTGGG
CATTGCTGATGCCTTGTCTAAAGCCTTAGTTAGCCGTGTCCTGTTATCCGTCGTCCCCAATGACAGTTCTATGCATTTAG
CTTGTTATGAGGCGACCCACGAAAGCCTGATGGCGCGTTTGCGTGAGCATAAACTGGATATGATCCTCTCCGATTGCGCC
GGTGAATCACTGAAGTATCCCGAAATCTTATCTAAAAAGTTGGGCGAGTGTGGTGTGAGTTTTTTCTCCGCTGATACTTA
TAGTGCTGATTTCCCCGCCTGTTTAGAGCAAGGCCAGCTATTAATTCCCGGCCGCAGAACCTCACTTGGACAGCAGTTAT
ATCGCTGGTTTGACGAACAAAATCTTAAAGTCAGTATCTTGGGTGAGTTCGACGATGCGGCCATGATGAAGGCCTTTGGT
TACCTTAAACGGGGGATTTTTGTCACGCCGTCGATTTATCGCCAAGAAGTGATTTCCCATGGGATGAATTTGCTCGGTGA
AACCACGGATGTGAAAGAGGAATACCATGTGATGTTTGCCGAACGTATGATCCAACATCCTGCGGTAAAGCGCTTGTTGG
ACACAGATTTCAGCGATCTCTTTGCGGGACGCGATATGCAAGTCCAACAATGCTAA

Upstream 100 bases:

>100_bases
GGAGCAATTACAAGGCATAGTCACTAACTTGCTTGATTGCCAGCGTTTGCAATAAACTGATTTATAACAATAGGTTTTAA
TCCCTCTGCGCCTTGGGCGT

Downstream 100 bases:

>100_bases
TTTTGTGAGCCAATGTGAAGGGTTAATCGACACTTTAGTCACTGAACTGATAGACTAATGCCAAATCTGTGTTGGGAGAA
ATACCTTGGAATTAATGAAC

Product: transcriptional activator NhaR

Products: NA

Alternate protein names: Na(+)/H(+) antiporter regulatory protein [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MRDDSQRMSMLHLNYNHLYYFWMIKKKGSVAKAAEALCLTPQTITGQIRALEDRLNGSLFKRVGRTLEATELGELVFRYA
DKMFSLSYEMLDLLNYQKDDAMLFEVGIADALSKALVSRVLLSVVPNDSSMHLACYEATHESLMARLREHKLDMILSDCA
GESLKYPEILSKKLGECGVSFFSADTYSADFPACLEQGQLLIPGRRTSLGQQLYRWFDEQNLKVSILGEFDDAAMMKAFG
YLKRGIFVTPSIYRQEVISHGMNLLGETTDVKEEYHVMFAERMIQHPAVKRLLDTDFSDLFAGRDMQVQQC

Sequences:

>Translated_311_residues
MRDDSQRMSMLHLNYNHLYYFWMIKKKGSVAKAAEALCLTPQTITGQIRALEDRLNGSLFKRVGRTLEATELGELVFRYA
DKMFSLSYEMLDLLNYQKDDAMLFEVGIADALSKALVSRVLLSVVPNDSSMHLACYEATHESLMARLREHKLDMILSDCA
GESLKYPEILSKKLGECGVSFFSADTYSADFPACLEQGQLLIPGRRTSLGQQLYRWFDEQNLKVSILGEFDDAAMMKAFG
YLKRGIFVTPSIYRQEVISHGMNLLGETTDVKEEYHVMFAERMIQHPAVKRLLDTDFSDLFAGRDMQVQQC
>Mature_311_residues
MRDDSQRMSMLHLNYNHLYYFWMIKKKGSVAKAAEALCLTPQTITGQIRALEDRLNGSLFKRVGRTLEATELGELVFRYA
DKMFSLSYEMLDLLNYQKDDAMLFEVGIADALSKALVSRVLLSVVPNDSSMHLACYEATHESLMARLREHKLDMILSDCA
GESLKYPEILSKKLGECGVSFFSADTYSADFPACLEQGQLLIPGRRTSLGQQLYRWFDEQNLKVSILGEFDDAAMMKAFG
YLKRGIFVTPSIYRQEVISHGMNLLGETTDVKEEYHVMFAERMIQHPAVKRLLDTDFSDLFAGRDMQVQQC

Specific function: Plays a role in the positive regulation of nhaA (Probable) [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786202, Length=297, Percent_Identity=58.9225589225589, Blast_Score=363, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35458; Mature: 35458

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDDSQRMSMLHLNYNHLYYFWMIKKKGSVAKAAEALCLTPQTITGQIRALEDRLNGSLF
CCCCHHHHHEEEECCCEEEEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHH
KRVGRTLEATELGELVFRYADKMFSLSYEMLDLLNYQKDDAMLFEVGIADALSKALVSRV
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHH
LLSVVPNDSSMHLACYEATHESLMARLREHKLDMILSDCAGESLKYPEILSKKLGECGVS
HHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCH
FFSADTYSADFPACLEQGQLLIPGRRTSLGQQLYRWFDEQNLKVSILGEFDDAAMMKAFG
HHCCCCCCCCCHHHHHCCCEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHH
YLKRGIFVTPSIYRQEVISHGMNLLGETTDVKEEYHVMFAERMIQHPAVKRLLDTDFSDL
HHHCCEEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
FAGRDMQVQQC
HCCCCCCCCCC
>Mature Secondary Structure
MRDDSQRMSMLHLNYNHLYYFWMIKKKGSVAKAAEALCLTPQTITGQIRALEDRLNGSLF
CCCCHHHHHEEEECCCEEEEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHH
KRVGRTLEATELGELVFRYADKMFSLSYEMLDLLNYQKDDAMLFEVGIADALSKALVSRV
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHH
LLSVVPNDSSMHLACYEATHESLMARLREHKLDMILSDCAGESLKYPEILSKKLGECGVS
HHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCH
FFSADTYSADFPACLEQGQLLIPGRRTSLGQQLYRWFDEQNLKVSILGEFDDAAMMKAFG
HHCCCCCCCCCHHHHHCCCEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHH
YLKRGIFVTPSIYRQEVISHGMNLLGETTDVKEEYHVMFAERMIQHPAVKRLLDTDFSDL
HHHCCEEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
FAGRDMQVQQC
HCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8231807; 9457888; 10952301 [H]