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The map label for this gene is gcp

Identifier: 160874344

GI number: 160874344

Start: 1460860

End: 1461876

Strand: Direct

Name: gcp

Synonym: Sbal195_1225

Alternate gene names: 160874344

Gene position: 1460860-1461876 (Clockwise)

Preceding gene: 160874339

Following gene: 160874346

Centisome position: 27.32

GC content: 51.23

Gene sequence:

>1017_bases
ATGCGGGTTCTAGGTATTGAAACATCTTGTGACGAGACAGGTATCGCCGTCTATGACGATGAACTGGGCTTATTATCGCA
CACTTTATACAGTCAAGTTAAGCTGCATGCTGACTATGGTGGTGTGGTGCCTGAGTTGGCGTCGCGTGACCATGTACGCA
AAATTGTGCCGCTTATTCGTCAAGCGCTGAAAGATGCGAATACTGAAATGGCTGATCTCGACGGGATTGCCTACACCAAG
GGCCCAGGTTTGATTGGTGCTTTGCTTGTTGGTGCCTGTGTGGGGCGTTCACTGGCTTTTGCTTGGGACAAGCCTGCAAT
CGGTGTGCACCATATGGAAGGGCACCTGCTGGCGCCTATGCTCGAAGATGACGCGCCTGAGTTCCCCTTTGTGGCCTTAT
TAGTTTCCGGTGGCCATTCAATGTTGGTTAAAGTCGATGGGATTGGCCGCTATGAAGTGTTAGGTGAGTCGGTTGACGAT
GCCGCGGGTGAAGCATTCGATAAAACGGCCAAGTTGATGGGGCTGGATTATCCCGGTGGTCCGCGCTTAGCTAAACTGGC
TGCTAAAGGCTTACCCGCAGGTTATAAGTTCCCGCGGCCTATGACCGACAGACCTGGACTCGATTTTAGCTTTTCGGGTT
TAAAAACTTTTACCGCCAATACTATTGCCGCTGAACCTGACGATGAGCAAACGCGCGCCAATATTGCCCGTGCCTTTGAA
GAAGCCGTGGTTGATACGCTGGCGATTAAATGTCGTCGTGCGCTGAAGCAAACTGGCTATAACCGCTTAGTGATTGCCGG
TGGCGTGAGTGCGAATACGCGCTTAAGGGAAACCTTGGCCGAAATGATGAACTCGCTAGGTGGACAAGTGTTTTATCCCC
GCGGTGAGTTTTGTACCGATAACGGCGCAATGATTGCCTTTGCGGGATTGCAGCGTTTAAAGGCGGGACAACACGAAGAT
TTAGCGGTAAAAGGTCAACCTCGATGGCCATTAGATACCTTGCCACCTGTGGCATAA

Upstream 100 bases:

>100_bases
GCTCAGTCCTATAGTGGACTCAATATGGCCTGTGCGACTGGAGTAATCGAGCGCTTGCAGGTAGAATTAGCGCCCTTTTG
TTAGCAATTGATGAGACACC

Downstream 100 bases:

>100_bases
CACGCCTTTGATGCCGATGTATTGATGCTGAAATAAAAAACTGCGCTTTTAGCGCAGTTTTTTATTGGGGTAATTTTATT
GGGCGTAATGTCATCTCAAG

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MRVLGIETSCDETGIAVYDDELGLLSHTLYSQVKLHADYGGVVPELASRDHVRKIVPLIRQALKDANTEMADLDGIAYTK
GPGLIGALLVGACVGRSLAFAWDKPAIGVHHMEGHLLAPMLEDDAPEFPFVALLVSGGHSMLVKVDGIGRYEVLGESVDD
AAGEAFDKTAKLMGLDYPGGPRLAKLAAKGLPAGYKFPRPMTDRPGLDFSFSGLKTFTANTIAAEPDDEQTRANIARAFE
EAVVDTLAIKCRRALKQTGYNRLVIAGGVSANTRLRETLAEMMNSLGGQVFYPRGEFCTDNGAMIAFAGLQRLKAGQHED
LAVKGQPRWPLDTLPPVA

Sequences:

>Translated_338_residues
MRVLGIETSCDETGIAVYDDELGLLSHTLYSQVKLHADYGGVVPELASRDHVRKIVPLIRQALKDANTEMADLDGIAYTK
GPGLIGALLVGACVGRSLAFAWDKPAIGVHHMEGHLLAPMLEDDAPEFPFVALLVSGGHSMLVKVDGIGRYEVLGESVDD
AAGEAFDKTAKLMGLDYPGGPRLAKLAAKGLPAGYKFPRPMTDRPGLDFSFSGLKTFTANTIAAEPDDEQTRANIARAFE
EAVVDTLAIKCRRALKQTGYNRLVIAGGVSANTRLRETLAEMMNSLGGQVFYPRGEFCTDNGAMIAFAGLQRLKAGQHED
LAVKGQPRWPLDTLPPVA
>Mature_338_residues
MRVLGIETSCDETGIAVYDDELGLLSHTLYSQVKLHADYGGVVPELASRDHVRKIVPLIRQALKDANTEMADLDGIAYTK
GPGLIGALLVGACVGRSLAFAWDKPAIGVHHMEGHLLAPMLEDDAPEFPFVALLVSGGHSMLVKVDGIGRYEVLGESVDD
AAGEAFDKTAKLMGLDYPGGPRLAKLAAKGLPAGYKFPRPMTDRPGLDFSFSGLKTFTANTIAAEPDDEQTRANIARAFE
EAVVDTLAIKCRRALKQTGYNRLVIAGGVSANTRLRETLAEMMNSLGGQVFYPRGEFCTDNGAMIAFAGLQRLKAGQHED
LAVKGQPRWPLDTLPPVA

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=355, Percent_Identity=34.3661971830986, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI8923380, Length=333, Percent_Identity=33.033033033033, Blast_Score=145, Evalue=4e-35,
Organism=Escherichia coli, GI1789445, Length=335, Percent_Identity=75.2238805970149, Blast_Score=517, Evalue=1e-148,
Organism=Caenorhabditis elegans, GI17557464, Length=329, Percent_Identity=30.0911854103343, Blast_Score=151, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI71995670, Length=330, Percent_Identity=34.2424242424242, Blast_Score=146, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6320099, Length=376, Percent_Identity=33.5106382978723, Blast_Score=173, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6322891, Length=348, Percent_Identity=28.735632183908, Blast_Score=122, Evalue=7e-29,
Organism=Drosophila melanogaster, GI20129063, Length=342, Percent_Identity=34.5029239766082, Blast_Score=181, Evalue=7e-46,
Organism=Drosophila melanogaster, GI21357207, Length=332, Percent_Identity=31.6265060240964, Blast_Score=154, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_SHEB2 (B8EBV5)

Other databases:

- EMBL:   CP001252
- RefSeq:   YP_002359073.1
- ProteinModelPortal:   B8EBV5
- SMR:   B8EBV5
- MEROPS:   M22.001
- GeneID:   7085778
- GenomeReviews:   CP001252_GR
- KEGG:   sbp:Sbal223_3165
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- ProtClustDB:   PRK09604
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 36246; Mature: 36246

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLGIETSCDETGIAVYDDELGLLSHTLYSQVKLHADYGGVVPELASRDHVRKIVPLIR
CEEEECCCCCCCCCCEEEECCHHHHHHHHHHHEEEECCCCCCCHHHHCHHHHHHHHHHHH
QALKDANTEMADLDGIAYTKGPGLIGALLVGACVGRSLAFAWDKPAIGVHHMEGHLLAPM
HHHHHCCCCHHHCCCEEEECCCCHHHHHHHHHHHCCCCEEECCCCCCCEEECCCCEECCH
LEDDAPEFPFVALLVSGGHSMLVKVDGIGRYEVLGESVDDAAGEAFDKTAKLMGLDYPGG
HCCCCCCCCEEEEEEECCCEEEEEECCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
PRLAKLAAKGLPAGYKFPRPMTDRPGLDFSFSGLKTFTANTIAAEPDDEQTRANIARAFE
CHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCCEEEECCEEECCCCCHHHHHHHHHHHH
EAVVDTLAIKCRRALKQTGYNRLVIAGGVSANTRLRETLAEMMNSLGGQVFYPRGEFCTD
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCEEEECCCCEECC
NGAMIAFAGLQRLKAGQHEDLAVKGQPRWPLDTLPPVA
CCCEEEHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MRVLGIETSCDETGIAVYDDELGLLSHTLYSQVKLHADYGGVVPELASRDHVRKIVPLIR
CEEEECCCCCCCCCCEEEECCHHHHHHHHHHHEEEECCCCCCCHHHHCHHHHHHHHHHHH
QALKDANTEMADLDGIAYTKGPGLIGALLVGACVGRSLAFAWDKPAIGVHHMEGHLLAPM
HHHHHCCCCHHHCCCEEEECCCCHHHHHHHHHHHCCCCEEECCCCCCCEEECCCCEECCH
LEDDAPEFPFVALLVSGGHSMLVKVDGIGRYEVLGESVDDAAGEAFDKTAKLMGLDYPGG
HCCCCCCCCEEEEEEECCCEEEEEECCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
PRLAKLAAKGLPAGYKFPRPMTDRPGLDFSFSGLKTFTANTIAAEPDDEQTRANIARAFE
CHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCCEEEECCEEECCCCCHHHHHHHHHHHH
EAVVDTLAIKCRRALKQTGYNRLVIAGGVSANTRLRETLAEMMNSLGGQVFYPRGEFCTD
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCEEEECCCCEECC
NGAMIAFAGLQRLKAGQHEDLAVKGQPRWPLDTLPPVA
CCCEEEHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA