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The map label for this gene is hlyB [H]

Identifier: 160874339

GI number: 160874339

Start: 1453506

End: 1455626

Strand: Direct

Name: hlyB [H]

Synonym: Sbal195_1220

Alternate gene names: 160874339

Gene position: 1453506-1455626 (Clockwise)

Preceding gene: 160874338

Following gene: 160874344

Centisome position: 27.18

GC content: 46.86

Gene sequence:

>2121_bases
ATGAAGCATTTGTCCATCAGTACTAAGTTGTTGTGGATTACATCAGCATTATTTTTATCGATAGTGGCTATTTTATCTAT
CAGTTTATGGTGGACGCTGTCGGCTCAAAACGCACAATTGTCGGATCAAGTTCAAAATACCCTACAAACGGAAACGCGGG
ATAAACTCGAAGCCCGCGCCGGTGAATATGGTGAAATGGTCGCCGGATTTATCAATGAAGCCTACCGAATTCCTTTCTCT
TTTGCGGGTATGCTTGAAAGTACTGCCGAGGAATTACCCTTAAAACGTGACCGCTTAGAACTCGCAGTAGCGGCAGTGCT
GAAGAAGAATGCGCAAGTCTCTTCCATGTATGCCCAGTTCGAACCTAATGGTTATGATGGGCTCGACAGTGAGTTTTTGA
ATGTTAATGTCAGTCACAGTGTGGCGACATCTGGCGCTCTAGAGGTCTATTACACCCGTAACGACGATGGCACTGTGGAG
CATAACCAAGTTGAAGATTCGGCAGAAAAGTACCTCACTAGCTTAAATGAGTTTGGGATCCGTGATGCTGAATGGTATTT
ATGTGGTAAAGAAACCTTAAAGCCCTGTTTAATGGAGCCGTACTTATACGAGATCACTCCAGGCAACAAAGCATTAATGA
CCTCGTTGACTGTGCCCGTGCTTAAACATAAGCAATTTATCGGTATAGTCGGTGTAGATGTAAACTTGCCAGTTTTTCAA
ACCCTTATCGATAAGTTATCCAAAAGCCTCTACGATGGACAAGCGAAAGTGACTTTGCTGAGCACCCGCGGTTTAGTGGT
CGCGGCCAGTCATTACAGTAAAAAGGCGCGTCCATTAGCTGAGTCGATAAATCCTACTCTCGCTTCGCAAATCATCTCCC
TGCACAAGAATTCCGGCTACATGGTTAACGATGATGAAATTATTGTTGCCTATCCCATTAAGATCCCGCTAGCGAATGCC
GAGTGGTCCTTGGTTATCCAAGTGCCGACTGCACAGGCATATAAGAGCTCGATTGAGCTAAATAATGATATGGATGAGAT
GGCGACTTCCTTAGGCAGTTTGCTGCTGATCGTGGGTATTGTGGTATCGATTGCCGCTGTGATTACCATTAGCTTAGTGA
TCCGTAGCATTATCTCACCATTGAGGATGATCCAGGGCCGTGTAGAGCATCTTGCGAGTGCCGATGGCGATTTAACGCAA
TCGATTGAGGTTGATTCCCATGCTGAATTGATTGCGTTAGCAAAAGGTTTCAACTCCTTTATTTATAAACTTAAAAATCT
GATTGCCGAGCTTAAAACGCTTGCGAGCCGCTCTCAGGAGGAAAGCCAAGCCTCTGCGAAAATTGCGCAGCTCACCCGTG
ACAGTGTGAATCGCCAGTACGGTGAAATTGAGAGTGTGGTAACGGCTGTGAATCAAATGAGTGCTACTGCACTAGAAGTT
GCTAAGGCGTCTGAGCAAACAGCGGCAGAAACTGAAGCTATGTCGCGCAATATTCGTCATAGCGAAGAGAGCCTGACTAA
AGCAATGGGTTTTGTCGCGACTATGTCTCAGGAGTCTATGGAGGCTAAGCTGGCGGTGAGTAAAGTGGCTGAGAGCAGTA
TGAACATCAGTCGTATCCTTGAGGTGATAAGCTCCATTGCCGCACAGACTAACCTGTTGGCACTCAATGCGGCGATTGAA
GCTGCAAGGGCGGGTGAGCAGGGACGAGGCTTTGCTGTGGTTGCTGACGAAGTCCGCGCGCTAGCATCTAAGACTCAGAG
CTCGACGAACGACATTAGTACCCTTATCGACGCACTGCAAAAAGAGGTCCAAAGCGCTTCTGGCATCATAGATAAAGGTG
CTGAGCGGGCACAAATGGCCGTATCTCAAACTGAGCAAGCGTTAAACTCATTAAATTCAATGGTGAGTCAGATTGGGGAG
ATTTCGGGCCAAGTGACTCATATTGCCGCCGCCGCAGAAGAGCAGAGTGCGGTGACTGAAGAGGTTAACCGCAATATCAC
CGGGATTTCTGACTCAGCTTCTGAACTTGCACGTCTTGCGGGTGAAGCACAGCAAAGCAGTGTAGTTTTAGCAAACTTAG
TGAAGCAGCAGCATGAGCAGTTAGGTAAGTTAAAAACCTAG

Upstream 100 bases:

>100_bases
ATTCTTACGCTAAGTGCTATTTTTAATGCTGGGTAGAAAGTATAAAAATGAATTAGATCATAATAATTACGCTATTGTCG
TTCTCTTGGGAGTTTACTAG

Downstream 100 bases:

>100_bases
CACGCAGAGGTTTACTGAATTAGCGCATTGATTTTAAATAGGCTCTTTAATTGTGTTGTTGGTTAAGCACTGATCAAAGG
GCCTATTTTTATGGTAATTG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 706; Mature: 706

Protein sequence:

>706_residues
MKHLSISTKLLWITSALFLSIVAILSISLWWTLSAQNAQLSDQVQNTLQTETRDKLEARAGEYGEMVAGFINEAYRIPFS
FAGMLESTAEELPLKRDRLELAVAAVLKKNAQVSSMYAQFEPNGYDGLDSEFLNVNVSHSVATSGALEVYYTRNDDGTVE
HNQVEDSAEKYLTSLNEFGIRDAEWYLCGKETLKPCLMEPYLYEITPGNKALMTSLTVPVLKHKQFIGIVGVDVNLPVFQ
TLIDKLSKSLYDGQAKVTLLSTRGLVVAASHYSKKARPLAESINPTLASQIISLHKNSGYMVNDDEIIVAYPIKIPLANA
EWSLVIQVPTAQAYKSSIELNNDMDEMATSLGSLLLIVGIVVSIAAVITISLVIRSIISPLRMIQGRVEHLASADGDLTQ
SIEVDSHAELIALAKGFNSFIYKLKNLIAELKTLASRSQEESQASAKIAQLTRDSVNRQYGEIESVVTAVNQMSATALEV
AKASEQTAAETEAMSRNIRHSEESLTKAMGFVATMSQESMEAKLAVSKVAESSMNISRILEVISSIAAQTNLLALNAAIE
AARAGEQGRGFAVVADEVRALASKTQSSTNDISTLIDALQKEVQSASGIIDKGAERAQMAVSQTEQALNSLNSMVSQIGE
ISGQVTHIAAAAEEQSAVTEEVNRNITGISDSASELARLAGEAQQSSVVLANLVKQQHEQLGKLKT

Sequences:

>Translated_706_residues
MKHLSISTKLLWITSALFLSIVAILSISLWWTLSAQNAQLSDQVQNTLQTETRDKLEARAGEYGEMVAGFINEAYRIPFS
FAGMLESTAEELPLKRDRLELAVAAVLKKNAQVSSMYAQFEPNGYDGLDSEFLNVNVSHSVATSGALEVYYTRNDDGTVE
HNQVEDSAEKYLTSLNEFGIRDAEWYLCGKETLKPCLMEPYLYEITPGNKALMTSLTVPVLKHKQFIGIVGVDVNLPVFQ
TLIDKLSKSLYDGQAKVTLLSTRGLVVAASHYSKKARPLAESINPTLASQIISLHKNSGYMVNDDEIIVAYPIKIPLANA
EWSLVIQVPTAQAYKSSIELNNDMDEMATSLGSLLLIVGIVVSIAAVITISLVIRSIISPLRMIQGRVEHLASADGDLTQ
SIEVDSHAELIALAKGFNSFIYKLKNLIAELKTLASRSQEESQASAKIAQLTRDSVNRQYGEIESVVTAVNQMSATALEV
AKASEQTAAETEAMSRNIRHSEESLTKAMGFVATMSQESMEAKLAVSKVAESSMNISRILEVISSIAAQTNLLALNAAIE
AARAGEQGRGFAVVADEVRALASKTQSSTNDISTLIDALQKEVQSASGIIDKGAERAQMAVSQTEQALNSLNSMVSQIGE
ISGQVTHIAAAAEEQSAVTEEVNRNITGISDSASELARLAGEAQQSSVVLANLVKQQHEQLGKLKT
>Mature_706_residues
MKHLSISTKLLWITSALFLSIVAILSISLWWTLSAQNAQLSDQVQNTLQTETRDKLEARAGEYGEMVAGFINEAYRIPFS
FAGMLESTAEELPLKRDRLELAVAAVLKKNAQVSSMYAQFEPNGYDGLDSEFLNVNVSHSVATSGALEVYYTRNDDGTVE
HNQVEDSAEKYLTSLNEFGIRDAEWYLCGKETLKPCLMEPYLYEITPGNKALMTSLTVPVLKHKQFIGIVGVDVNLPVFQ
TLIDKLSKSLYDGQAKVTLLSTRGLVVAASHYSKKARPLAESINPTLASQIISLHKNSGYMVNDDEIIVAYPIKIPLANA
EWSLVIQVPTAQAYKSSIELNNDMDEMATSLGSLLLIVGIVVSIAAVITISLVIRSIISPLRMIQGRVEHLASADGDLTQ
SIEVDSHAELIALAKGFNSFIYKLKNLIAELKTLASRSQEESQASAKIAQLTRDSVNRQYGEIESVVTAVNQMSATALEV
AKASEQTAAETEAMSRNIRHSEESLTKAMGFVATMSQESMEAKLAVSKVAESSMNISRILEVISSIAAQTNLLALNAAIE
AARAGEQGRGFAVVADEVRALASKTQSSTNDISTLIDALQKEVQSASGIIDKGAERAQMAVSQTEQALNSLNSMVSQIGE
ISGQVTHIAAAAEEQSAVTEEVNRNITGISDSASELARLAGEAQQSSVVLANLVKQQHEQLGKLKT

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=345, Percent_Identity=29.2753623188406, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1787690, Length=350, Percent_Identity=31.1428571428571, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI1788195, Length=311, Percent_Identity=28.2958199356913, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1788194, Length=347, Percent_Identity=30.2593659942363, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1789453, Length=179, Percent_Identity=35.7541899441341, Blast_Score=96, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 76379; Mature: 76379

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHLSISTKLLWITSALFLSIVAILSISLWWTLSAQNAQLSDQVQNTLQTETRDKLEARA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHC
GEYGEMVAGFINEAYRIPFSFAGMLESTAEELPLKRDRLELAVAAVLKKNAQVSSMYAQF
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHC
EPNGYDGLDSEFLNVNVSHSVATSGALEVYYTRNDDGTVEHNQVEDSAEKYLTSLNEFGI
CCCCCCCCCCCCEEEEECHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCC
RDAEWYLCGKETLKPCLMEPYLYEITPGNKALMTSLTVPVLKHKQFIGIVGVDVNLPVFQ
CCCCEEEECHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCEEEEEEECCCCHHHH
TLIDKLSKSLYDGQAKVTLLSTRGLVVAASHYSKKARPLAESINPTLASQIISLHKNSGY
HHHHHHHHHHHCCCCEEEEEEECCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCE
MVNDDEIIVAYPIKIPLANAEWSLVIQVPTAQAYKSSIELNNDMDEMATSLGSLLLIVGI
EECCCCEEEEEEEEEEECCCCEEEEEECCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
VVSIAAVITISLVIRSIISPLRMIQGRVEHLASADGDLTQSIEVDSHAELIALAKGFNSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
IYKLKNLIAELKTLASRSQEESQASAKIAQLTRDSVNRQYGEIESVVTAVNQMSATALEV
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKASEQTAAETEAMSRNIRHSEESLTKAMGFVATMSQESMEAKLAVSKVAESSMNISRIL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
EVISSIAAQTNLLALNAAIEAARAGEQGRGFAVVADEVRALASKTQSSTNDISTLIDALQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHCCCHHHHHHHHHHHH
KEVQSASGIIDKGAERAQMAVSQTEQALNSLNSMVSQIGEISGQVTHIAAAAEEQSAVTE
HHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
EVNRNITGISDSASELARLAGEAQQSSVVLANLVKQQHEQLGKLKT
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKHLSISTKLLWITSALFLSIVAILSISLWWTLSAQNAQLSDQVQNTLQTETRDKLEARA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHC
GEYGEMVAGFINEAYRIPFSFAGMLESTAEELPLKRDRLELAVAAVLKKNAQVSSMYAQF
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHC
EPNGYDGLDSEFLNVNVSHSVATSGALEVYYTRNDDGTVEHNQVEDSAEKYLTSLNEFGI
CCCCCCCCCCCCEEEEECHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCC
RDAEWYLCGKETLKPCLMEPYLYEITPGNKALMTSLTVPVLKHKQFIGIVGVDVNLPVFQ
CCCCEEEECHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCEEEEEEECCCCHHHH
TLIDKLSKSLYDGQAKVTLLSTRGLVVAASHYSKKARPLAESINPTLASQIISLHKNSGY
HHHHHHHHHHHCCCCEEEEEEECCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCE
MVNDDEIIVAYPIKIPLANAEWSLVIQVPTAQAYKSSIELNNDMDEMATSLGSLLLIVGI
EECCCCEEEEEEEEEEECCCCEEEEEECCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
VVSIAAVITISLVIRSIISPLRMIQGRVEHLASADGDLTQSIEVDSHAELIALAKGFNSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
IYKLKNLIAELKTLASRSQEESQASAKIAQLTRDSVNRQYGEIESVVTAVNQMSATALEV
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKASEQTAAETEAMSRNIRHSEESLTKAMGFVATMSQESMEAKLAVSKVAESSMNISRIL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
EVISSIAAQTNLLALNAAIEAARAGEQGRGFAVVADEVRALASKTQSSTNDISTLIDALQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHCCCHHHHHHHHHHHH
KEVQSASGIIDKGAERAQMAVSQTEQALNSLNSMVSQIGEISGQVTHIAAAAEEQSAVTE
HHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
EVNRNITGISDSASELARLAGEAQQSSVVLANLVKQQHEQLGKLKT
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]