Click here to switch to the map view.

The map label for this gene is hlyB [H]

Identifier: 160874296

GI number: 160874296

Start: 1393005

End: 1394492

Strand: Direct

Name: hlyB [H]

Synonym: Sbal195_1176

Alternate gene names: 160874296

Gene position: 1393005-1394492 (Clockwise)

Preceding gene: 160874295

Following gene: 160874297

Centisome position: 26.05

GC content: 48.39

Gene sequence:

>1488_bases
ATGAAAACATTAGCCTTAAAAGTACAGATTGGGTTAGCGGCAGCGATTTTTATGATAGTCAGCGTTTTGTTCGGTGCATC
TTACTGGTTGGCGAGCGATAAATTGGCCGCCAGTGAAACTGAGTTTGAAGACAATACCGTCGCCAATTTGCAAGTCACTA
TGGCGCAGCCCATCTTCACCTACGATTATGAACAAATCCAAGCCGTGTTGTCTGTCATGCTTAAATCTGCGCAGATTTAT
CATATCGTGGTGAGCGACCATCGCGGTAAAGTGTTAGCCGAGAGTCAACAGGCTCAAACGGTGGCCGATGAGTATCTGGT
AAAACGTGAAATTCACTTTGCTGACCAAGGCAATCCGACGGGCCAATTGGCCATTCAGTTTTCTATGTTGCCAATTCGCG
CTCAGTTGTCAGATTTACTCTTAGGTTATTTCTTGCAGGCGTTGTTAATTCTCGGTGGCAGTTTATTTGTTATCTTCATT
ATTCTTAAACGTTTAGTGATTAATCCACTTGAGAATGTGGTTCGCGCCATGGAAGAAATTGCCAGCGGTGACGGTGATTT
ATGCCACAGATTACCGGTTGAGAGTCAGGATGAGATTGGTCAGCTTGCCAAGGCATTTAATGGTTTTGTAGAGCAAATTC
ACGGCACGATTTCCAGAGTGCACGAAACCTCAGGGCAATTACTGGGCGATGCCAAAGCGCTTGGTTCACTGTCGCAAACC
AACAATGATCGCGTGCAAACCCAACTAAAAGAAACCGAGGCAGCAGTAACGGCTGTGACTCAGCTGAGCGCCAGTGCTAA
CGAAGTTGCGATTAACGCCAAGCGCACCGCGGATGCGGCGAGTCAGGCCGATAAAGCGGTCGATGACAGTCAGCGTCAGT
TTGATTCGGGATTAGATATTACCCGCAAGCTGGCATCTGAATTAGCTCGCTCGGCATTGTCCGTCTCACAGTTACAGCAA
GAAACCCAAAAGATTGATGAAGTGGTCGTAGTGATCAACAGTATTGCCGAACAGACCAACTTACTGGCGCTTAATGCTGC
TATTGAAGCGGCAAGGGCGGGTGAACAAGGGCGCGGTTTTGCTGTGGTGGCCGACGAAGTGCGCACGCTGGCGAGCCGAA
CCCAACAAGCCACAGGTGAAATACAGAAAATGATCCAGCAGGTTCAGAGCCGTGTGGCAGAAACGGTCACTGTGATGCAA
GCGAGTCAAGCCCTCTCGACTCAGGGCGTAAACCGCTCGGAAGAAATTAAGTTAGTACTCACTAAAGTGACTGATTTAGT
CTCAAATATCAGTAATATGAACATCGAAGTTTCCCATGCGGCGCAGGAGCAAACCTGCGTCACCGAAGCGATTTCTCGTA
CGTTAAATGATCTTGCCAATGTCTCAGGTTCAGCCTCACTCGATAGCGAGCACTTAGCGCACTCGAGCGAGCGACTGTTT
CACCAAGGGGAAAGACTGCGGACGTTAGTAACTTCCTTCAGATTGTAG

Upstream 100 bases:

>100_bases
GGGTCATTATCCGCCTCGATACGCCTGATTTAAGTCCGTTAACGCCAATAGATCGCAAAGAATTATGGTTAGATCTCTTT
AGTATGCAAGGTGCAAAATA

Downstream 100 bases:

>100_bases
CCATTTCTGGAGCTAGATAAGGATAATCATGAATAAAACACTCTCAGCAAGCGCCATTTTACTGGCTTTAGGATTAGCGG
CCTGTTCCGAGGCGCCAGTG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 495

Protein sequence:

>495_residues
MKTLALKVQIGLAAAIFMIVSVLFGASYWLASDKLAASETEFEDNTVANLQVTMAQPIFTYDYEQIQAVLSVMLKSAQIY
HIVVSDHRGKVLAESQQAQTVADEYLVKREIHFADQGNPTGQLAIQFSMLPIRAQLSDLLLGYFLQALLILGGSLFVIFI
ILKRLVINPLENVVRAMEEIASGDGDLCHRLPVESQDEIGQLAKAFNGFVEQIHGTISRVHETSGQLLGDAKALGSLSQT
NNDRVQTQLKETEAAVTAVTQLSASANEVAINAKRTADAASQADKAVDDSQRQFDSGLDITRKLASELARSALSVSQLQQ
ETQKIDEVVVVINSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQQATGEIQKMIQQVQSRVAETVTVMQ
ASQALSTQGVNRSEEIKLVLTKVTDLVSNISNMNIEVSHAAQEQTCVTEAISRTLNDLANVSGSASLDSEHLAHSSERLF
HQGERLRTLVTSFRL

Sequences:

>Translated_495_residues
MKTLALKVQIGLAAAIFMIVSVLFGASYWLASDKLAASETEFEDNTVANLQVTMAQPIFTYDYEQIQAVLSVMLKSAQIY
HIVVSDHRGKVLAESQQAQTVADEYLVKREIHFADQGNPTGQLAIQFSMLPIRAQLSDLLLGYFLQALLILGGSLFVIFI
ILKRLVINPLENVVRAMEEIASGDGDLCHRLPVESQDEIGQLAKAFNGFVEQIHGTISRVHETSGQLLGDAKALGSLSQT
NNDRVQTQLKETEAAVTAVTQLSASANEVAINAKRTADAASQADKAVDDSQRQFDSGLDITRKLASELARSALSVSQLQQ
ETQKIDEVVVVINSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQQATGEIQKMIQQVQSRVAETVTVMQ
ASQALSTQGVNRSEEIKLVLTKVTDLVSNISNMNIEVSHAAQEQTCVTEAISRTLNDLANVSGSASLDSEHLAHSSERLF
HQGERLRTLVTSFRL
>Mature_495_residues
MKTLALKVQIGLAAAIFMIVSVLFGASYWLASDKLAASETEFEDNTVANLQVTMAQPIFTYDYEQIQAVLSVMLKSAQIY
HIVVSDHRGKVLAESQQAQTVADEYLVKREIHFADQGNPTGQLAIQFSMLPIRAQLSDLLLGYFLQALLILGGSLFVIFI
ILKRLVINPLENVVRAMEEIASGDGDLCHRLPVESQDEIGQLAKAFNGFVEQIHGTISRVHETSGQLLGDAKALGSLSQT
NNDRVQTQLKETEAAVTAVTQLSASANEVAINAKRTADAASQADKAVDDSQRQFDSGLDITRKLASELARSALSVSQLQQ
ETQKIDEVVVVINSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQQATGEIQKMIQQVQSRVAETVTVMQ
ASQALSTQGVNRSEEIKLVLTKVTDLVSNISNMNIEVSHAAQEQTCVTEAISRTLNDLANVSGSASLDSEHLAHSSERLF
HQGERLRTLVTSFRL

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=359, Percent_Identity=32.033426183844, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1788195, Length=279, Percent_Identity=32.258064516129, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI2367378, Length=305, Percent_Identity=29.5081967213115, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788194, Length=337, Percent_Identity=29.080118694362, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1789453, Length=387, Percent_Identity=28.1653746770026, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 53728; Mature: 53728

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLALKVQIGLAAAIFMIVSVLFGASYWLASDKLAASETEFEDNTVANLQVTMAQPIFT
CCCEEEEEHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCEEEEEEEEECCHHH
YDYEQIQAVLSVMLKSAQIYHIVVSDHRGKVLAESQQAQTVADEYLVKREIHFADQGNPT
CCHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHCHHHHHHHHHHHHHHHHHHCCCCCCCC
GQLAIQFSMLPIRAQLSDLLLGYFLQALLILGGSLFVIFIILKRLVINPLENVVRAMEEI
CEEEEEEEECHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASGDGDLCHRLPVESQDEIGQLAKAFNGFVEQIHGTISRVHETSGQLLGDAKALGSLSQT
HCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCC
NNDRVQTQLKETEAAVTAVTQLSASANEVAINAKRTADAASQADKAVDDSQRQFDSGLDI
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCHHHHHHHCCCHH
TRKLASELARSALSVSQLQQETQKIDEVVVVINSIAEQTNLLALNAAIEAARAGEQGRGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
AVVADEVRTLASRTQQATGEIQKMIQQVQSRVAETVTVMQASQALSTQGVNRSEEIKLVL
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
TKVTDLVSNISNMNIEVSHAAQEQTCVTEAISRTLNDLANVSGSASLDSEHLAHSSERLF
HHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
HQGERLRTLVTSFRL
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTLALKVQIGLAAAIFMIVSVLFGASYWLASDKLAASETEFEDNTVANLQVTMAQPIFT
CCCEEEEEHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCEEEEEEEEECCHHH
YDYEQIQAVLSVMLKSAQIYHIVVSDHRGKVLAESQQAQTVADEYLVKREIHFADQGNPT
CCHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHCHHHHHHHHHHHHHHHHHHCCCCCCCC
GQLAIQFSMLPIRAQLSDLLLGYFLQALLILGGSLFVIFIILKRLVINPLENVVRAMEEI
CEEEEEEEECHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASGDGDLCHRLPVESQDEIGQLAKAFNGFVEQIHGTISRVHETSGQLLGDAKALGSLSQT
HCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCC
NNDRVQTQLKETEAAVTAVTQLSASANEVAINAKRTADAASQADKAVDDSQRQFDSGLDI
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCHHHHHHHCCCHH
TRKLASELARSALSVSQLQQETQKIDEVVVVINSIAEQTNLLALNAAIEAARAGEQGRGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
AVVADEVRTLASRTQQATGEIQKMIQQVQSRVAETVTVMQASQALSTQGVNRSEEIKLVL
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
TKVTDLVSNISNMNIEVSHAAQEQTCVTEAISRTLNDLANVSGSASLDSEHLAHSSERLF
HHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
HQGERLRTLVTSFRL
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]