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The map label for this gene is mreB [H]

Identifier: 160873640

GI number: 160873640

Start: 593337

End: 594386

Strand: Direct

Name: mreB [H]

Synonym: Sbal195_0518

Alternate gene names: 160873640

Gene position: 593337-594386 (Clockwise)

Preceding gene: 160873639

Following gene: 160873641

Centisome position: 11.1

GC content: 48.76

Gene sequence:

>1050_bases
ATGTTTAAGAAGCTACGCGGCATTTTTTCTAATGATCTATCGATCGATTTGGGTACAGCTAACACATTAATTTATGTTCG
TGGCGAAGGCATAGTGCTCAATGAGCCTTCTGTTGTTGCTATACGTGGTGAGCGTGGTGGCTCCGGTCAGAAATCTGTTG
CCGCGGTCGGCACAGAAGCTAAACAAATGCTCGGCAGAACGCCTGGCAATATCCAAGCTATCCGCCCAATGAAGGACGGT
GTAATCGCTGACTTTTATGTGACTGAGAAAATGCTGCAGCACTTTATCAAACAAGTGCACAACAATAGCTTTTTTCGTCC
AAGTCCACGGGTTCTAGTGTGTGTGCCAGTTGGCGCCACTCAAGTTGAACGCCGTGCGATCCGTGAATCAGCCATGGGCG
CTGGTGCTCGCGAAGTGTATTTGATTGAAGAACCTATGGCTGCTGCGATTGGTGCGGGTTTACCTGTATCTGAAGCGACG
GGTTCTATGGTAGTGGACATCGGTGGTGGTACCACTGAAGTCGCGATTATTTCGCTGAATGGCGTAGTGTATTCGTCTTC
CGTCCGTATCGGTGGTGACAAGTTTGATGATGCGATCATCAACTATGTTCGCCGTAACTACGGTAGCTTAATTGGTGAAG
CCACGGCTGAGCGTATCAAGCACACTATCGGTACTGCTTATCCTGGCGATGAAGTGCTAGAGATCGAAGTCCGCGGCCGT
AACTTGGCTGAAGGTGTACCTCGTAGCTTTACACTGAACAGCAACGAAATTTTAGAGGCCTTACAAGAGCCATTATCTGG
CATCGTAAGTGCTGTGATGGTGGCGTTAGAACAATCTCCACCAGAATTAGCTTCAGATATTTCTGAGCGCGGTATGGTGT
TAACTGGCGGTGGTGCGTTATTGCGTGATTTAGACCGTTTATTAATGCAAGAAACCGGCATTCCAGTAATGGTGGCGGAC
GATCCATTGACCTGCGTAGCACGTGGCGGTGGTAAAGCCCTCGAAATGATTGATATGCACGGCGGCGATCTGTTCTCCGA
AGAAACCTAA

Upstream 100 bases:

>100_bases
AGCGATTGTTAACCTCCTCGGTCTTGTGGAATCAGGGTGGCATTGATAAAGTTAGCTGATTTTTCTTTTCTTCTGACTCC
ACAGAATACAGGCTAGTTAC

Downstream 100 bases:

>100_bases
TTTAACTTCGGTATAGGGCGGTTAATCACCGCCTTAGCTTTCCTATGAAGCCAATTTTTGTTCGTGGTATTTCAAACCAA
TTCCGTCTGACACTGGCAAT

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MFKKLRGIFSNDLSIDLGTANTLIYVRGEGIVLNEPSVVAIRGERGGSGQKSVAAVGTEAKQMLGRTPGNIQAIRPMKDG
VIADFYVTEKMLQHFIKQVHNNSFFRPSPRVLVCVPVGATQVERRAIRESAMGAGAREVYLIEEPMAAAIGAGLPVSEAT
GSMVVDIGGGTTEVAIISLNGVVYSSSVRIGGDKFDDAIINYVRRNYGSLIGEATAERIKHTIGTAYPGDEVLEIEVRGR
NLAEGVPRSFTLNSNEILEALQEPLSGIVSAVMVALEQSPPELASDISERGMVLTGGGALLRDLDRLLMQETGIPVMVAD
DPLTCVARGGGKALEMIDMHGGDLFSEET

Sequences:

>Translated_349_residues
MFKKLRGIFSNDLSIDLGTANTLIYVRGEGIVLNEPSVVAIRGERGGSGQKSVAAVGTEAKQMLGRTPGNIQAIRPMKDG
VIADFYVTEKMLQHFIKQVHNNSFFRPSPRVLVCVPVGATQVERRAIRESAMGAGAREVYLIEEPMAAAIGAGLPVSEAT
GSMVVDIGGGTTEVAIISLNGVVYSSSVRIGGDKFDDAIINYVRRNYGSLIGEATAERIKHTIGTAYPGDEVLEIEVRGR
NLAEGVPRSFTLNSNEILEALQEPLSGIVSAVMVALEQSPPELASDISERGMVLTGGGALLRDLDRLLMQETGIPVMVAD
DPLTCVARGGGKALEMIDMHGGDLFSEET
>Mature_349_residues
MFKKLRGIFSNDLSIDLGTANTLIYVRGEGIVLNEPSVVAIRGERGGSGQKSVAAVGTEAKQMLGRTPGNIQAIRPMKDG
VIADFYVTEKMLQHFIKQVHNNSFFRPSPRVLVCVPVGATQVERRAIRESAMGAGAREVYLIEEPMAAAIGAGLPVSEAT
GSMVVDIGGGTTEVAIISLNGVVYSSSVRIGGDKFDDAIINYVRRNYGSLIGEATAERIKHTIGTAYPGDEVLEIEVRGR
NLAEGVPRSFTLNSNEILEALQEPLSGIVSAVMVALEQSPPELASDISERGMVLTGGGALLRDLDRLLMQETGIPVMVAD
DPLTCVARGGGKALEMIDMHGGDLFSEET

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=348, Percent_Identity=91.0919540229885, Blast_Score=635, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319972, Length=360, Percent_Identity=22.7777777777778, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 37128; Mature: 37128

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKKLRGIFSNDLSIDLGTANTLIYVRGEGIVLNEPSVVAIRGERGGSGQKSVAAVGTEA
CCHHHHHHHCCCCEEEECCCCEEEEEECCEEEECCCCEEEEECCCCCCCCCHHHHHCHHH
KQMLGRTPGNIQAIRPMKDGVIADFYVTEKMLQHFIKQVHNNSFFRPSPRVLVCVPVGAT
HHHHCCCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHH
QVERRAIRESAMGAGAREVYLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAIISLN
HHHHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEEEEC
GVVYSSSVRIGGDKFDDAIINYVRRNYGSLIGEATAERIKHTIGTAYPGDEVLEIEVRGR
CEEEECEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCC
NLAEGVPRSFTLNSNEILEALQEPLSGIVSAVMVALEQSPPELASDISERGMVLTGGGAL
CHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEECCCHH
LRDLDRLLMQETGIPVMVADDPLTCVARGGGKALEMIDMHGGDLFSEET
HHHHHHHHHHHCCCEEEEECCCEEEEECCCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MFKKLRGIFSNDLSIDLGTANTLIYVRGEGIVLNEPSVVAIRGERGGSGQKSVAAVGTEA
CCHHHHHHHCCCCEEEECCCCEEEEEECCEEEECCCCEEEEECCCCCCCCCHHHHHCHHH
KQMLGRTPGNIQAIRPMKDGVIADFYVTEKMLQHFIKQVHNNSFFRPSPRVLVCVPVGAT
HHHHCCCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHH
QVERRAIRESAMGAGAREVYLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAIISLN
HHHHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEEEEC
GVVYSSSVRIGGDKFDDAIINYVRRNYGSLIGEATAERIKHTIGTAYPGDEVLEIEVRGR
CEEEECEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCC
NLAEGVPRSFTLNSNEILEALQEPLSGIVSAVMVALEQSPPELASDISERGMVLTGGGAL
CHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEECCCHH
LRDLDRLLMQETGIPVMVADDPLTCVARGGGKALEMIDMHGGDLFSEET
HHHHHHHHHHHCCCEEEEECCCEEEEECCCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]