Click here to switch to the map view.

The map label for this gene is udp [H]

Identifier: 160873610

GI number: 160873610

Start: 558809

End: 559567

Strand: Direct

Name: udp [H]

Synonym: Sbal195_0488

Alternate gene names: 160873610

Gene position: 558809-559567 (Clockwise)

Preceding gene: 160873608

Following gene: 160873612

Centisome position: 10.45

GC content: 48.35

Gene sequence:

>759_bases
ATGGCTGATGTATTTCATTTAGGTTTGACCAAAGCAATGCTCGATGGTGCAACTTTGGCAATCGTTCCTGGTGATCCAGA
GCGCGTAAAACGTATTGCCGAACTAATGGACAATGCGACGTTTCTTGCTAGCCACCGCGAGTATACAAGCTATTTAGCTT
ATGCCGATGGCAAGCCAGTAGTCGTGTGTTCAACCGGTATCGGTGGTCCATCGACTTCTATCGCAGTAGAAGAACTTGCA
CAGTTAGGTGTGAATACCTTCCTGCGCGTTGGTACTACAGGTGCAATTCAACCCCATGTGAATGTGGGCGATGTGATTGT
GACTCAAGCTTCAGTGCGTTTAGATGGCGCGAGCTTACACTTTGCACCTATGGAGTTCCCTGCGGTTGCAAACTTTGAAT
GTACCACTGCTATGGTTGCAGCGTGTCGCGATGCAGGCGTAGAGCCACACATTGGCGTAACGGCTTCTTCTGATACTTTC
TACCCAGGCCAAGAGCGTTATGACACTGTCACTGGCCGTGTAACGCGTCGTTTCGCGGGTTCAATGAAAGAATGGCAAGA
TATGGGTGTACTGAACTATGAGATGGAATCTTCCACTTTGTTCACTATGTGTGCCACTCAAGGCTGGCGTGCAGCCTGTG
TTGCTGGTGTGATTGTAAACCGCACCCAACAAGAAATTCCTGATGAAGCTACAATGAAGAAAACCGAAGTAAGCGCGGTT
TCTATCGTGGTTGCAGCAGCGAAAAAACTGTTAGCCTAA

Upstream 100 bases:

>100_bases
GCCGATAATTCTGTGATCAAGTTAACCTTCACCGCTTCGATACTAGGTTAAAGTCGATTTTATAAGAATTTAATTATCAA
AAATGAAAGGGGTTTTCACA

Downstream 100 bases:

>100_bases
TTTTTATTACGCTAAGCGACACTCCCCTGCAAAGTGAGTGACCAAACTAAAAAAGGTGCCAATGGCACCTTTTTTGTTAC
TTCAAAATTGTGTCTATACC

Product: uridine phosphorylase

Products: NA

Alternate protein names: UPase; UrdPase [H]

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MADVFHLGLTKAMLDGATLAIVPGDPERVKRIAELMDNATFLASHREYTSYLAYADGKPVVVCSTGIGGPSTSIAVEELA
QLGVNTFLRVGTTGAIQPHVNVGDVIVTQASVRLDGASLHFAPMEFPAVANFECTTAMVAACRDAGVEPHIGVTASSDTF
YPGQERYDTVTGRVTRRFAGSMKEWQDMGVLNYEMESSTLFTMCATQGWRAACVAGVIVNRTQQEIPDEATMKKTEVSAV
SIVVAAAKKLLA

Sequences:

>Translated_252_residues
MADVFHLGLTKAMLDGATLAIVPGDPERVKRIAELMDNATFLASHREYTSYLAYADGKPVVVCSTGIGGPSTSIAVEELA
QLGVNTFLRVGTTGAIQPHVNVGDVIVTQASVRLDGASLHFAPMEFPAVANFECTTAMVAACRDAGVEPHIGVTASSDTF
YPGQERYDTVTGRVTRRFAGSMKEWQDMGVLNYEMESSTLFTMCATQGWRAACVAGVIVNRTQQEIPDEATMKKTEVSAV
SIVVAAAKKLLA
>Mature_251_residues
ADVFHLGLTKAMLDGATLAIVPGDPERVKRIAELMDNATFLASHREYTSYLAYADGKPVVVCSTGIGGPSTSIAVEELAQ
LGVNTFLRVGTTGAIQPHVNVGDVIVTQASVRLDGASLHFAPMEFPAVANFECTTAMVAACRDAGVEPHIGVTASSDTFY
PGQERYDTVTGRVTRRFAGSMKEWQDMGVLNYEMESSTLFTMCATQGWRAACVAGVIVNRTQQEIPDEATMKKTEVSAVS
IVVAAAKKLLA

Specific function: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synth

COG id: COG2820

COG function: function code F; Uridine phosphorylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790265, Length=250, Percent_Identity=75.6, Blast_Score=399, Evalue=1e-112,
Organism=Escherichia coli, GI1790844, Length=214, Percent_Identity=30.3738317757009, Blast_Score=91, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845
- InterPro:   IPR010058 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.3 [H]

Molecular weight: Translated: 26855; Mature: 26724

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADVFHLGLTKAMLDGATLAIVPGDPERVKRIAELMDNATFLASHREYTSYLAYADGKPV
CCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCEECCCHHHHHEEEECCCCEE
VVCSTGIGGPSTSIAVEELAQLGVNTFLRVGTTGAIQPHVNVGDVIVTQASVRLDGASLH
EEEECCCCCCCHHHHHHHHHHHCHHHHHHCCCCCCCCCCCCCCCEEEEEEEEEECCCEEE
FAPMEFPAVANFECTTAMVAACRDAGVEPHIGVTASSDTFYPGQERYDTVTGRVTRRFAG
ECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHC
SMKEWQDMGVLNYEMESSTLFTMCATQGWRAACVAGVIVNRTQQEIPDEATMKKTEVSAV
CHHHHHHCCCEEEEECCCEEEEEECCCCCHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHH
SIVVAAAKKLLA
HHHHHHHHHHCC
>Mature Secondary Structure 
ADVFHLGLTKAMLDGATLAIVPGDPERVKRIAELMDNATFLASHREYTSYLAYADGKPV
CCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCEECCCHHHHHEEEECCCCEE
VVCSTGIGGPSTSIAVEELAQLGVNTFLRVGTTGAIQPHVNVGDVIVTQASVRLDGASLH
EEEECCCCCCCHHHHHHHHHHHCHHHHHHCCCCCCCCCCCCCCCEEEEEEEEEECCCEEE
FAPMEFPAVANFECTTAMVAACRDAGVEPHIGVTASSDTFYPGQERYDTVTGRVTRRFAG
ECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHC
SMKEWQDMGVLNYEMESSTLFTMCATQGWRAACVAGVIVNRTQQEIPDEATMKKTEVSAV
CHHHHHHCCCEEEEECCCEEEEEECCCCCHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHH
SIVVAAAKKLLA
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2674901; 1379743; 9278503; 8506346; 8899705; 9661793; 7796917; 12499542 [H]