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The map label for this gene is ldc [H]

Identifier: 160873608

GI number: 160873608

Start: 556943

End: 558118

Strand: Direct

Name: ldc [H]

Synonym: Sbal195_0486

Alternate gene names: 160873608

Gene position: 556943-558118 (Clockwise)

Preceding gene: 160873607

Following gene: 160873610

Centisome position: 10.42

GC content: 45.32

Gene sequence:

>1176_bases
ATGAGCCAATTTCAATCTATTGATGTTGCTGACTATTATGACGTGGATACATTCAAGCGTATTGAAGCGTTTGCCAAAGA
CAAAGCAACCCCGTTCGTAGTGATTGATACCAGTATCATAGCGAAACAATACGATGACATGGTTAATAGTTTTCCTTACG
CCAACGTTTATTATGCAGTTAAGGCAAACCCCGCGGCCGAGATCTTATCTTTACTTAAAGATAAAGGGTCAAACTTTGAT
ATTGCCTCGATTTATGAGCTAGATATGGTTATGAATGTCGGCGTGACAACCGACCGAGTCAGCTACGGCAATACCATTAA
AAAGCGTCAAGATGTACGTGCATTTTATGAGCGTGGTGTGCGTATGTATGCATCCGACTCAGAAGCCGATCTGCGAATGA
TCGCCGAAGAAGCTCCGGGATCGCGTATTTACGTGCGCATTTTGACCGAAGGTACAGATACGGCTGATTGGCCGTTATCG
CGTAAATTCGGCTGCCAAAACGAAATGGCCTATGAGCTATTAGTATTGGCGCAGGAATTGGGTTTAGAACCTTTTGGTAT
TTCGTTTCACGTCGGTTCACAGCAACGTGACATCGGTGCTTGGGATTCTGCCATAGGTAAAGTGAAAAGCATTTTTGACC
GTCTGCGTGATGAGCACAATATCACCCTGAAGATGATCAACATGGGCGGCGGTTTCCCTGCTAACTATATTGATAAAACC
AATCAATTGGGTGTGTATGCCGAGCAGATCACTCACTTCCTGAAGGAAGATTTCGGTGACGATTTACCGCAAATTATTCT
GGAGCCGGGTCGTTCGTTGATTTCTAACGCGGGGATTTTAGTGTCTGAAGTGGTACTGATCAGCAAAAAATCCTACACAG
CGTTAGAGCGTTGGGTGTTTACCGATGTGGGTAAATTCTCTGGCTTAATTGAAACGATGGACGAGGCGATTAAGTTCCCG
ATTTATACCGATCGTCAAGGCGAGCTGGATAAATGCGTGATTGCCGGCCCAACCTGCGACAGTGCCGATATCATGTATGA
GCACTACAGCTACGGTTTACCGAATGACTTAGCTATTGGTGACCGCATGTATTGGTTAACCGCTGGCGCTTATACGACGA
CGTATTCGGCAGTGTGCTTTAACGGTTTCCCACCGCTGAAAGATTACTATCTGTAA

Upstream 100 bases:

>100_bases
AAATTCGTTGCGTAAAGCAAAAAAATATCGTTTACTGCGCACGTTTTTTAAGACATTACACTCACTTTTTTCTACTTGAC
CCAAAGGAGACTCTGGCCCA

Downstream 100 bases:

>100_bases
GCGATTGTGGTGACATGAATAAGGGCGCTTAGGCGCCCTTGTTGTTCGCTAAAGAAGTTTGGGATTACTCGTGGGATTTG
AGGATCTGATAAATCTCTTC

Product: diaminopimelate decarboxylase

Products: NA

Alternate protein names: LDC [H]

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MSQFQSIDVADYYDVDTFKRIEAFAKDKATPFVVIDTSIIAKQYDDMVNSFPYANVYYAVKANPAAEILSLLKDKGSNFD
IASIYELDMVMNVGVTTDRVSYGNTIKKRQDVRAFYERGVRMYASDSEADLRMIAEEAPGSRIYVRILTEGTDTADWPLS
RKFGCQNEMAYELLVLAQELGLEPFGISFHVGSQQRDIGAWDSAIGKVKSIFDRLRDEHNITLKMINMGGGFPANYIDKT
NQLGVYAEQITHFLKEDFGDDLPQIILEPGRSLISNAGILVSEVVLISKKSYTALERWVFTDVGKFSGLIETMDEAIKFP
IYTDRQGELDKCVIAGPTCDSADIMYEHYSYGLPNDLAIGDRMYWLTAGAYTTTYSAVCFNGFPPLKDYYL

Sequences:

>Translated_391_residues
MSQFQSIDVADYYDVDTFKRIEAFAKDKATPFVVIDTSIIAKQYDDMVNSFPYANVYYAVKANPAAEILSLLKDKGSNFD
IASIYELDMVMNVGVTTDRVSYGNTIKKRQDVRAFYERGVRMYASDSEADLRMIAEEAPGSRIYVRILTEGTDTADWPLS
RKFGCQNEMAYELLVLAQELGLEPFGISFHVGSQQRDIGAWDSAIGKVKSIFDRLRDEHNITLKMINMGGGFPANYIDKT
NQLGVYAEQITHFLKEDFGDDLPQIILEPGRSLISNAGILVSEVVLISKKSYTALERWVFTDVGKFSGLIETMDEAIKFP
IYTDRQGELDKCVIAGPTCDSADIMYEHYSYGLPNDLAIGDRMYWLTAGAYTTTYSAVCFNGFPPLKDYYL
>Mature_390_residues
SQFQSIDVADYYDVDTFKRIEAFAKDKATPFVVIDTSIIAKQYDDMVNSFPYANVYYAVKANPAAEILSLLKDKGSNFDI
ASIYELDMVMNVGVTTDRVSYGNTIKKRQDVRAFYERGVRMYASDSEADLRMIAEEAPGSRIYVRILTEGTDTADWPLSR
KFGCQNEMAYELLVLAQELGLEPFGISFHVGSQQRDIGAWDSAIGKVKSIFDRLRDEHNITLKMINMGGGFPANYIDKTN
QLGVYAEQITHFLKEDFGDDLPQIILEPGRSLISNAGILVSEVVLISKKSYTALERWVFTDVGKFSGLIETMDEAIKFPI
YTDRQGELDKCVIAGPTCDSADIMYEHYSYGLPNDLAIGDRMYWLTAGAYTTTYSAVCFNGFPPLKDYYL

Specific function: Decarboxylates both L-lysine and L-ornithine with similar catalytic efficiency [H]

COG id: COG0019

COG function: function code E; Diaminopimelate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family [H]

Homologues:

Organism=Homo sapiens, GI4505489, Length=392, Percent_Identity=29.8469387755102, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI22538418, Length=381, Percent_Identity=24.6719160104987, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI21361583, Length=381, Percent_Identity=24.6719160104987, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI16506287, Length=372, Percent_Identity=24.1935483870968, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17562780, Length=372, Percent_Identity=29.3010752688172, Blast_Score=146, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6322664, Length=383, Percent_Identity=30.5483028720627, Blast_Score=160, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24586472, Length=375, Percent_Identity=28, Blast_Score=128, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24586474, Length=359, Percent_Identity=29.2479108635098, Blast_Score=113, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183
- InterPro:   IPR002433 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.17; =4.1.1.18 [H]

Molecular weight: Translated: 43989; Mature: 43858

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS00878 ODR_DC_2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQFQSIDVADYYDVDTFKRIEAFAKDKATPFVVIDTSIIAKQYDDMVNSFPYANVYYAV
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCCEEEEEE
KANPAAEILSLLKDKGSNFDIASIYELDMVMNVGVTTDRVSYGNTIKKRQDVRAFYERGV
ECCCHHHHHHHHHCCCCCCCHHHHEEEEHHEECCCCCCCCCCCCHHHHHHHHHHHHHCCC
RMYASDSEADLRMIAEEAPGSRIYVRILTEGTDTADWPLSRKFGCQNEMAYELLVLAQEL
EEEECCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
GLEPFGISFHVGSQQRDIGAWDSAIGKVKSIFDRLRDEHNITLKMINMGGGFPANYIDKT
CCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHCCC
NQLGVYAEQITHFLKEDFGDDLPQIILEPGRSLISNAGILVSEVVLISKKSYTALERWVF
CCCCHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHCCCHHHHHHHHHCCCCHHHHHHHHH
TDVGKFSGLIETMDEAIKFPIYTDRQGELDKCVIAGPTCDSADIMYEHYSYGLPNDLAIG
HHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCEEC
DRMYWLTAGAYTTTYSAVCFNGFPPLKDYYL
CEEEEEEECCHHHEEHEEEECCCCCHHHCCC
>Mature Secondary Structure 
SQFQSIDVADYYDVDTFKRIEAFAKDKATPFVVIDTSIIAKQYDDMVNSFPYANVYYAV
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCCEEEEEE
KANPAAEILSLLKDKGSNFDIASIYELDMVMNVGVTTDRVSYGNTIKKRQDVRAFYERGV
ECCCHHHHHHHHHCCCCCCCHHHHEEEEHHEECCCCCCCCCCCCHHHHHHHHHHHHHCCC
RMYASDSEADLRMIAEEAPGSRIYVRILTEGTDTADWPLSRKFGCQNEMAYELLVLAQEL
EEEECCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
GLEPFGISFHVGSQQRDIGAWDSAIGKVKSIFDRLRDEHNITLKMINMGGGFPANYIDKT
CCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHCCC
NQLGVYAEQITHFLKEDFGDDLPQIILEPGRSLISNAGILVSEVVLISKKSYTALERWVF
CCCCHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHCCCHHHHHHHHHCCCCHHHHHHHHH
TDVGKFSGLIETMDEAIKFPIYTDRQGELDKCVIAGPTCDSADIMYEHYSYGLPNDLAIG
HHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCEEC
DRMYWLTAGAYTTTYSAVCFNGFPPLKDYYL
CEEEEEEECCHHHEEHEEEECCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11073919 [H]