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The map label for this gene is glpK [H]

Identifier: 160873527

GI number: 160873527

Start: 457856

End: 459340

Strand: Direct

Name: glpK [H]

Synonym: Sbal195_0402

Alternate gene names: 160873527

Gene position: 457856-459340 (Clockwise)

Preceding gene: 160873526

Following gene: 160873529

Centisome position: 8.56

GC content: 50.37

Gene sequence:

>1485_bases
GTGCAGAAAAAATACGTGGTGGCTTTAGATCAAGGCACGACCAGCTCAAGGGCGATAGTGTTCGATCACGATGCAAACAT
TGTCAGCGTGTCCCAGCGGGAATTCACCCAGTTGTATCCGAATCCGGGTTGGGTCGAGCATGATCCCATGGAGATCTGGG
CAAGCCAAAGTTCAGTATTAATTGAAGTGCTGGCGCGCGCGGGGATCCACAGCGATGAAGTGGCCGCGATTGGCATTACC
AATCAGCGGGAAACTACAGTCATTTGGGAGAAAGCCACAGGTAAACCTATCTATAACGCGATTGTGTGGCAGTGCCGTCG
TAGCTCTGAAATTTGTGAGCAACTCAAAGCTCAAGGATTAGAAGAGTATGTCCGTGAAAACACAGGCCTGTTACTCGACC
CTTATTTTTCAGGCACTAAGATCAAGTGGATTCTAGATAATGTGCCCAATGCCCGTGCGCAAGCCGAGCGCGGTGAGTTG
TTGTTCGGCACTATCGATACTTGGCTAGTGTGGAAGTTAACCGAGGGCAAAGTGCATGTCACCGATCCCACCAATGCCGC
CCGTACTCTGCTGTTTAATATCCATAGTCTGACTTGGGATAACAAGTTACTTGAAGCTTTAAACATTCCCTTGTCTTTAT
TGCCCGAAGTTAAGCCTTCCTGCAGTGTCTATGGCACCACACGGATTGCCGGTGAAGGCAGTGAAATCCAAGTTGCAGGA
ATGGCGGGCGACCAACAGGCTGCGCTTTTTGGTCAGTTGTGTGTCGAGCCTGGCATGGCGAAGAATACCTATGGCACTGG
CTGTTTTTTATTGATGAATACCGGGACCAAAGCGGTGCGCTCTAACCATGGGTTACTGACCACAGTTGCCGTGGGACCGA
AGGGCGAAGTGAACTATGCCCTCGAAGGTTCAGTCTTCATGGGTGGCGCGACTATTCAATGGCTGCGCGATGAACTTGGG
CTTATTCGTGACGCCAGTGATACTGAGTATTTTGCCTCTAAGGTTGCTGATACCAATGGCGTGTATTTAGTGCCCGCTTT
TGTTGGACTCGGGGCGCCCTATTGGGATCCCAATGCCCGTGGCGCAATCTTTGGTTTAACCCGTGGCGCCAACCGTAATC
ATATTATTCGGGCGGCGTTAGAATCCATTGCTTATCAGAGTAAAGATTTACTCGATGCCATGACCAAAGACAGTGGCGTT
AGCCTTAAGCGTTTGAAGGTGGATGGCGGCGCGGTCGCCAATGATTTTTTGATGCAGTTTCAAGCCGATATCACCGATGT
CGAAGTACTAAGGCCGAGTGTTTGTGAGACAACGGCTTTGGGCGCGGCATTTTTAGCTGGGTTGGCTGTGGGCTTTTGGG
AGAGTGTCATAGAGCTTGAACATAAAGCTTGTATCGATAAGCATTTTATCCCCAATATTGATGCCGAGACTCGGGTGCGG
TTATACGCAGGTTGGCAAGATGCCGTCGCCAGAACTCGCGCCTAA

Upstream 100 bases:

>100_bases
CACGGCAGAAAATTGCGAATATATTCATTGCATAAGTAGTGGATCATGTTAACTCTCACCGGCATAAAAAGGCGGCGGAG
AGTTCAGATAGGATAGTAGC

Downstream 100 bases:

>100_bases
GCTATTCGACTTAAGCTATTCAACTCAAGTCGTTGGACTTGAGACATGCTTAAATTTGATATTGAGTTGGTTTGAAATGT
GACTCGATTGTGGTGAATAA

Product: glycerol kinase

Products: NA

Alternate protein names: ATP:glycerol 3-phosphotransferase; Glycerokinase; GK [H]

Number of amino acids: Translated: 494; Mature: 494

Protein sequence:

>494_residues
MQKKYVVALDQGTTSSRAIVFDHDANIVSVSQREFTQLYPNPGWVEHDPMEIWASQSSVLIEVLARAGIHSDEVAAIGIT
NQRETTVIWEKATGKPIYNAIVWQCRRSSEICEQLKAQGLEEYVRENTGLLLDPYFSGTKIKWILDNVPNARAQAERGEL
LFGTIDTWLVWKLTEGKVHVTDPTNAARTLLFNIHSLTWDNKLLEALNIPLSLLPEVKPSCSVYGTTRIAGEGSEIQVAG
MAGDQQAALFGQLCVEPGMAKNTYGTGCFLLMNTGTKAVRSNHGLLTTVAVGPKGEVNYALEGSVFMGGATIQWLRDELG
LIRDASDTEYFASKVADTNGVYLVPAFVGLGAPYWDPNARGAIFGLTRGANRNHIIRAALESIAYQSKDLLDAMTKDSGV
SLKRLKVDGGAVANDFLMQFQADITDVEVLRPSVCETTALGAAFLAGLAVGFWESVIELEHKACIDKHFIPNIDAETRVR
LYAGWQDAVARTRA

Sequences:

>Translated_494_residues
MQKKYVVALDQGTTSSRAIVFDHDANIVSVSQREFTQLYPNPGWVEHDPMEIWASQSSVLIEVLARAGIHSDEVAAIGIT
NQRETTVIWEKATGKPIYNAIVWQCRRSSEICEQLKAQGLEEYVRENTGLLLDPYFSGTKIKWILDNVPNARAQAERGEL
LFGTIDTWLVWKLTEGKVHVTDPTNAARTLLFNIHSLTWDNKLLEALNIPLSLLPEVKPSCSVYGTTRIAGEGSEIQVAG
MAGDQQAALFGQLCVEPGMAKNTYGTGCFLLMNTGTKAVRSNHGLLTTVAVGPKGEVNYALEGSVFMGGATIQWLRDELG
LIRDASDTEYFASKVADTNGVYLVPAFVGLGAPYWDPNARGAIFGLTRGANRNHIIRAALESIAYQSKDLLDAMTKDSGV
SLKRLKVDGGAVANDFLMQFQADITDVEVLRPSVCETTALGAAFLAGLAVGFWESVIELEHKACIDKHFIPNIDAETRVR
LYAGWQDAVARTRA
>Mature_494_residues
MQKKYVVALDQGTTSSRAIVFDHDANIVSVSQREFTQLYPNPGWVEHDPMEIWASQSSVLIEVLARAGIHSDEVAAIGIT
NQRETTVIWEKATGKPIYNAIVWQCRRSSEICEQLKAQGLEEYVRENTGLLLDPYFSGTKIKWILDNVPNARAQAERGEL
LFGTIDTWLVWKLTEGKVHVTDPTNAARTLLFNIHSLTWDNKLLEALNIPLSLLPEVKPSCSVYGTTRIAGEGSEIQVAG
MAGDQQAALFGQLCVEPGMAKNTYGTGCFLLMNTGTKAVRSNHGLLTTVAVGPKGEVNYALEGSVFMGGATIQWLRDELG
LIRDASDTEYFASKVADTNGVYLVPAFVGLGAPYWDPNARGAIFGLTRGANRNHIIRAALESIAYQSKDLLDAMTKDSGV
SLKRLKVDGGAVANDFLMQFQADITDVEVLRPSVCETTALGAAFLAGLAVGFWESVIELEHKACIDKHFIPNIDAETRVR
LYAGWQDAVARTRA

Specific function: Key enzyme in the regulation of glycerol uptake and metabolism [H]

COG id: COG0554

COG function: function code C; Glycerol kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=504, Percent_Identity=48.2142857142857, Blast_Score=442, Evalue=1e-124,
Organism=Homo sapiens, GI189409120, Length=499, Percent_Identity=48.4969939879759, Blast_Score=442, Evalue=1e-124,
Organism=Homo sapiens, GI4504007, Length=499, Percent_Identity=48.4969939879759, Blast_Score=442, Evalue=1e-124,
Organism=Homo sapiens, GI41393575, Length=507, Percent_Identity=46.9428007889546, Blast_Score=432, Evalue=1e-121,
Organism=Homo sapiens, GI88196792, Length=504, Percent_Identity=33.7301587301587, Blast_Score=298, Evalue=5e-81,
Organism=Escherichia coli, GI1790361, Length=494, Percent_Identity=71.2550607287449, Blast_Score=763, Evalue=0.0,
Organism=Escherichia coli, GI1787789, Length=492, Percent_Identity=27.6422764227642, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1789987, Length=501, Percent_Identity=24.1516966067864, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1790005, Length=507, Percent_Identity=23.0769230769231, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1789138, Length=485, Percent_Identity=22.8865979381443, Blast_Score=95, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17535599, Length=498, Percent_Identity=42.3694779116466, Blast_Score=393, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI71986140, Length=516, Percent_Identity=24.031007751938, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI71986147, Length=262, Percent_Identity=29.7709923664122, Blast_Score=115, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6321755, Length=553, Percent_Identity=37.7938517179023, Blast_Score=309, Evalue=5e-85,
Organism=Drosophila melanogaster, GI17864214, Length=506, Percent_Identity=43.8735177865613, Blast_Score=402, Evalue=1e-112,
Organism=Drosophila melanogaster, GI24655555, Length=501, Percent_Identity=40.9181636726547, Blast_Score=391, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24655560, Length=501, Percent_Identity=40.9181636726547, Blast_Score=391, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24655570, Length=501, Percent_Identity=40.9181636726547, Blast_Score=391, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24655574, Length=501, Percent_Identity=40.9181636726547, Blast_Score=391, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24655565, Length=501, Percent_Identity=40.9181636726547, Blast_Score=391, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24654573, Length=443, Percent_Identity=45.372460496614, Blast_Score=372, Evalue=1e-103,
Organism=Drosophila melanogaster, GI19922058, Length=525, Percent_Identity=32.9523809523809, Blast_Score=274, Evalue=9e-74,
Organism=Drosophila melanogaster, GI24652871, Length=492, Percent_Identity=33.739837398374, Blast_Score=262, Evalue=3e-70,
Organism=Drosophila melanogaster, GI24656367, Length=510, Percent_Identity=28.4313725490196, Blast_Score=204, Evalue=9e-53,
Organism=Drosophila melanogaster, GI21357867, Length=525, Percent_Identity=28.1904761904762, Blast_Score=201, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24656372, Length=345, Percent_Identity=30.7246376811594, Blast_Score=156, Evalue=3e-38,
Organism=Drosophila melanogaster, GI45552909, Length=290, Percent_Identity=27.2413793103448, Blast_Score=108, Evalue=1e-23,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR005999 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.30 [H]

Molecular weight: Translated: 54039; Mature: 54039

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKKYVVALDQGTTSSRAIVFDHDANIVSVSQREFTQLYPNPGWVEHDPMEIWASQSSVL
CCCCEEEEEECCCCCCEEEEEECCCCEEEECHHHHHHHCCCCCCCCCCHHHHHCCCHHHH
IEVLARAGIHSDEVAAIGITNQRETTVIWEKATGKPIYNAIVWQCRRSSEICEQLKAQGL
HHHHHHCCCCCCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHCCH
EEYVRENTGLLLDPYFSGTKIKWILDNVPNARAQAERGELLFGTIDTWLVWKLTEGKVHV
HHHHHCCCCEEEECCCCCCEEEEEECCCCCCHHHCCCCCEEEEEECEEEEEEEECCEEEE
TDPTNAARTLLFNIHSLTWDNKLLEALNIPLSLLPEVKPSCSVYGTTRIAGEGSEIQVAG
ECCCCHHHEEEEEHHHCCCCHHHHHHHCCCHHHCCCCCCCCEEEEEEEEECCCCEEEEEE
MAGDQQAALFGQLCVEPGMAKNTYGTGCFLLMNTGTKAVRSNHGLLTTVAVGPKGEVNYA
CCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCHHHHCCCCEEEEEEECCCCCEEEE
LEGSVFMGGATIQWLRDELGLIRDASDTEYFASKVADTNGVYLVPAFVGLGAPYWDPNAR
EECCEEECCCHHHHHHHHHHHEECCCCHHHHHHHHCCCCCEEEEEEHHHCCCCCCCCCCC
GAIFGLTRGANRNHIIRAALESIAYQSKDLLDAMTKDSGVSLKRLKVDGGAVANDFLMQF
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHH
QADITDVEVLRPSVCETTALGAAFLAGLAVGFWESVIELEHKACIDKHFIPNIDAETRVR
HCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
LYAGWQDAVARTRA
EEECCHHHHHHCCC
>Mature Secondary Structure
MQKKYVVALDQGTTSSRAIVFDHDANIVSVSQREFTQLYPNPGWVEHDPMEIWASQSSVL
CCCCEEEEEECCCCCCEEEEEECCCCEEEECHHHHHHHCCCCCCCCCCHHHHHCCCHHHH
IEVLARAGIHSDEVAAIGITNQRETTVIWEKATGKPIYNAIVWQCRRSSEICEQLKAQGL
HHHHHHCCCCCCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHCCH
EEYVRENTGLLLDPYFSGTKIKWILDNVPNARAQAERGELLFGTIDTWLVWKLTEGKVHV
HHHHHCCCCEEEECCCCCCEEEEEECCCCCCHHHCCCCCEEEEEECEEEEEEEECCEEEE
TDPTNAARTLLFNIHSLTWDNKLLEALNIPLSLLPEVKPSCSVYGTTRIAGEGSEIQVAG
ECCCCHHHEEEEEHHHCCCCHHHHHHHCCCHHHCCCCCCCCEEEEEEEEECCCCEEEEEE
MAGDQQAALFGQLCVEPGMAKNTYGTGCFLLMNTGTKAVRSNHGLLTTVAVGPKGEVNYA
CCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCHHHHCCCCEEEEEEECCCCCEEEE
LEGSVFMGGATIQWLRDELGLIRDASDTEYFASKVADTNGVYLVPAFVGLGAPYWDPNAR
EECCEEECCCHHHHHHHHHHHEECCCCHHHHHHHHCCCCCEEEEEEHHHCCCCCCCCCCC
GAIFGLTRGANRNHIIRAALESIAYQSKDLLDAMTKDSGVSLKRLKVDGGAVANDFLMQF
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHH
QADITDVEVLRPSVCETTALGAAFLAGLAVGFWESVIELEHKACIDKHFIPNIDAETRVR
HCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
LYAGWQDAVARTRA
EEECCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA