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The map label for this gene is yjjG [H]

Identifier: 160873500

GI number: 160873500

Start: 429122

End: 429859

Strand: Direct

Name: yjjG [H]

Synonym: Sbal195_0375

Alternate gene names: 160873500

Gene position: 429122-429859 (Clockwise)

Preceding gene: 160873494

Following gene: 160873502

Centisome position: 8.03

GC content: 46.48

Gene sequence:

>738_bases
ATGCCACTGAACGGCATGGGGATGGGTCTTAGCTATTTTGTCAGAAAGAGAGTTCCTATGTCCTTGCCTTACCAATGGAT
TTTGTTCGATGCCGATGAAACCCTATTTTATTTCGATGCTTTAAAAGGGCTTAAGTTGATGTTTAGTGAGTTTGGGGTCG
ATTTTACCCAAGCCGATTTTGACGAGTATCAGTTAGTTAACAAACCACTTTGGGTTGATTATCAAGATGGCAAGATAACT
GCCGCCGAGTTGCAAACCATACGTTTCGAACCTTGGGCTGCCAAATTATCTGTCACGGCCATGACGCTCAATAGTGCCTT
TTTATCAGCAATGGCCGAAATTTGTTCGCCGCTACCCGGTGCCCGCGAGTTATTAGCCGCGCTCCAAGGCAAAGCCAAAT
TAGGTATCATCACTAACGGTTTCACTGAGCTACAAACCGTGCGATTAGAGCGTACAGGATTACAGCATCATTTTGATATT
TTAGTGATTTCAGAAAAAGTCGGCATAGCCAAACCTGATGTGGGTATCTTCGAACATGCTTTCGAACTCATGGGCCATCC
TGAGCGCGATGCTGTGCTCATGGTCGGTGATAACCCGCATTCAGATATCCAAGGCGGCATCAATGCCGGTATTCATACTT
GCTGGTATAACGTCCACGGCCACGATGTACCCGCCGGTATCGCCCCGCACTATCAAGTGAGCTCGCACCAAGAGCTATAT
AGTTTATTGTTCGGGTAA

Upstream 100 bases:

>100_bases
CTAGTTATTTTCGGGCTCATCGCTCATGTTTATCGCTTATCTTGATTACTGCTAGGCAGCTAGCCACAGCATTGCCGCAA
TCGCCGATGTACCATTCTCG

Downstream 100 bases:

>100_bases
GTCAACAGGCACTCAGCTTATGCTGTGAAGTCACTTAGCGAGTCAGCACTTCACGGATCTTACTTGCTTTATTTTTACCT
ATACCACCCACTTGCATCAA

Product: nucleotidase

Products: NA

Alternate protein names: House-cleaning nucleotidase; Non-canonical pyrimidine nucleotide phosphatase; Nucleoside 5'-monophosphate phosphohydrolase; dUMP phosphatase [H]

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MPLNGMGMGLSYFVRKRVPMSLPYQWILFDADETLFYFDALKGLKLMFSEFGVDFTQADFDEYQLVNKPLWVDYQDGKIT
AAELQTIRFEPWAAKLSVTAMTLNSAFLSAMAEICSPLPGARELLAALQGKAKLGIITNGFTELQTVRLERTGLQHHFDI
LVISEKVGIAKPDVGIFEHAFELMGHPERDAVLMVGDNPHSDIQGGINAGIHTCWYNVHGHDVPAGIAPHYQVSSHQELY
SLLFG

Sequences:

>Translated_245_residues
MPLNGMGMGLSYFVRKRVPMSLPYQWILFDADETLFYFDALKGLKLMFSEFGVDFTQADFDEYQLVNKPLWVDYQDGKIT
AAELQTIRFEPWAAKLSVTAMTLNSAFLSAMAEICSPLPGARELLAALQGKAKLGIITNGFTELQTVRLERTGLQHHFDI
LVISEKVGIAKPDVGIFEHAFELMGHPERDAVLMVGDNPHSDIQGGINAGIHTCWYNVHGHDVPAGIAPHYQVSSHQELY
SLLFG
>Mature_244_residues
PLNGMGMGLSYFVRKRVPMSLPYQWILFDADETLFYFDALKGLKLMFSEFGVDFTQADFDEYQLVNKPLWVDYQDGKITA
AELQTIRFEPWAAKLSVTAMTLNSAFLSAMAEICSPLPGARELLAALQGKAKLGIITNGFTELQTVRLERTGLQHHFDIL
VISEKVGIAKPDVGIFEHAFELMGHPERDAVLMVGDNPHSDIQGGINAGIHTCWYNVHGHDVPAGIAPHYQVSSHQELYS
LLFG

Specific function: Nucleotidase that shows high phosphatase activity toward non-canonical pyrimidine nucleotides and three canonical nucleoside 5'-monophosphates (UMP, dUMP, and dTMP), and very low activity against TDP, IMP, UDP, GMP, dGMP, AMP, dAMP, and 6- phosphogluconat

COG id: COG1011

COG function: function code R; Predicted hydrolase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. YjjG family [H]

Homologues:

Organism=Homo sapiens, GI23308749, Length=125, Percent_Identity=38.4, Blast_Score=75, Evalue=7e-14,
Organism=Escherichia coli, GI1790833, Length=222, Percent_Identity=60.3603603603604, Blast_Score=281, Evalue=2e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR011951 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.5 [H]

Molecular weight: Translated: 27290; Mature: 27158

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLNGMGMGLSYFVRKRVPMSLPYQWILFDADETLFYFDALKGLKLMFSEFGVDFTQADF
CCCCCCCCCHHHHHHHCCCCCCCEEEEEEECCCCEEHHHHHHHHHHHHHHHCCCCHHCCC
DEYQLVNKPLWVDYQDGKITAAELQTIRFEPWAAKLSVTAMTLNSAFLSAMAEICSPLPG
HHHHHHCCCEEEEECCCEEEHHHHEEEEECCCEEEEEEEEEHHHHHHHHHHHHHHCCCCC
ARELLAALQGKAKLGIITNGFTELQTVRLERTGLQHHFDILVISEKVGIAKPDVGIFEHA
HHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCHHHHHH
FELMGHPERDAVLMVGDNPHSDIQGGINAGIHTCWYNVHGHDVPAGIAPHYQVSSHQELY
HHHHCCCCCCEEEEECCCCCCHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHH
SLLFG
HHHCC
>Mature Secondary Structure 
PLNGMGMGLSYFVRKRVPMSLPYQWILFDADETLFYFDALKGLKLMFSEFGVDFTQADF
CCCCCCCCHHHHHHHCCCCCCCEEEEEEECCCCEEHHHHHHHHHHHHHHHCCCCHHCCC
DEYQLVNKPLWVDYQDGKITAAELQTIRFEPWAAKLSVTAMTLNSAFLSAMAEICSPLPG
HHHHHHCCCEEEEECCCEEEHHHHEEEEECCCEEEEEEEEEHHHHHHHHHHHHHHCCCCC
ARELLAALQGKAKLGIITNGFTELQTVRLERTGLQHHFDILVISEKVGIAKPDVGIFEHA
HHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCHHHHHH
FELMGHPERDAVLMVGDNPHSDIQGGINAGIHTCWYNVHGHDVPAGIAPHYQVSSHQELY
HHHHCCCCCCEEEEECCCCCCHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHH
SLLFG
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]