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The map label for this gene is xorIIM [H]

Identifier: 160873497

GI number: 160873497

Start: 425538

End: 426695

Strand: Reverse

Name: xorIIM [H]

Synonym: Sbal195_0372

Alternate gene names: 160873497

Gene position: 426695-425538 (Counterclockwise)

Preceding gene: 160873498

Following gene: 160873496

Centisome position: 7.98

GC content: 42.83

Gene sequence:

>1158_bases
ATGAAAGCGATAGATCTATTTTCAGGTGCTGGCGGCTTATCCCTTGCCGCACATCAATGTGGCATTGATGTTATCGCAGC
AATCGAACTAGATACGGCCGCTTCCATTACTTATCGAGCGAACTTAATTGAACAGCTAAAAGCACCAACAAAACTCATTA
ATGGTGACATTAATGAAGTCGATCTCCCAGCCTTGATGAAAGAGCTAAAGCTCAAATCCGGTGAGTTAGAATTATTGCTT
GGTGGTCCTCCATGCCAAGGCTTCTCGACGCATCGCATCAATAATGCTGGCATTGACGACCCTAGAAATCAGTTGCTGTT
AAAGTACTTCGATTTTGTCGATGGTCTGCAACCAAAAGCGTTCTTGATTGAAAACGTGGCGGGACTTTTATGGAAACGCC
ATGAAAACTATCTCAATCAGCTTCTAGCTCTCGCTGAAACTCACGGCTACACCATTCATTTTTGCGGAATACTAAACGCT
AAAGACTATGGCGTGCCACAAAACCGTAAACGTGTGTTTATTTTTGGTACACGTAACGATCTTAAGATTAACAATCCAGC
ATTTCCGCCTGATGCGACTCATTTTGCGCCAACATCTAAAAATGGGCCTAAATGGAAAACCGCGTCTAGCGTGTTTGAAA
AGCTCACTTCAGAATTAATAGACTTTTATATCGAAGATTATTTCCGTCCCAAAACGAAAATGACCGATGAAAATGCAAGA
TTACTATTAGCATCTTTAGAACACGGCGAACCAGTTAACCCGACTGACGTATGCAACATCAATATGCAGCCAACACCTAA
GATGATTATCCGATTCGAAAATACGCCTCTTAATGGGGGGCGAGAAGATTCAGGGTACACTCTAAAATGTCATTCGAATG
GCTATAAAGGCCATAAAGATGTGTATGGCCGGATCATGATCCACCTACCTGGCAACACCATAACTACGGGCTGTAACAAC
CCTTCAAAAGGCCGTTTTGTTCACCCCTGGAAGAACCATGGCATGACGCTACGCCATGCTGCTCGCTTCCAAACCTTTCC
TGACAGCTTTAACTTTATAGGCACTTCGACTCAACAAGGTAAACAGATAGGTAACGCTGTTCCAGTTGAATTAGGTAAAG
TGTTAATCAACACTATCAAGAGAATCATCACATCATAG

Upstream 100 bases:

>100_bases
ATCACAATTACAAACTCCTCAATCACAAACTAAAAGCTAGCGGAATAGTGCTTGCCATGTATAATTTGCGGTTCGAAATT
GGTGTGTGGGTTGATGATTA

Downstream 100 bases:

>100_bases
TCTAAAAGACTATTTATTATGACGTGAAAAAAGCATATTATCCTGACTAATAAGGAATTTTAGTTAGGGAAGCCAAATGC
TCACGTCAGTATCATTTCAA

Product: DNA-cytosine methyltransferase

Products: NA

Alternate protein names: M.XorII; Cytosine-specific methyltransferase XorII [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MKAIDLFSGAGGLSLAAHQCGIDVIAAIELDTAASITYRANLIEQLKAPTKLINGDINEVDLPALMKELKLKSGELELLL
GGPPCQGFSTHRINNAGIDDPRNQLLLKYFDFVDGLQPKAFLIENVAGLLWKRHENYLNQLLALAETHGYTIHFCGILNA
KDYGVPQNRKRVFIFGTRNDLKINNPAFPPDATHFAPTSKNGPKWKTASSVFEKLTSELIDFYIEDYFRPKTKMTDENAR
LLLASLEHGEPVNPTDVCNINMQPTPKMIIRFENTPLNGGREDSGYTLKCHSNGYKGHKDVYGRIMIHLPGNTITTGCNN
PSKGRFVHPWKNHGMTLRHAARFQTFPDSFNFIGTSTQQGKQIGNAVPVELGKVLINTIKRIITS

Sequences:

>Translated_385_residues
MKAIDLFSGAGGLSLAAHQCGIDVIAAIELDTAASITYRANLIEQLKAPTKLINGDINEVDLPALMKELKLKSGELELLL
GGPPCQGFSTHRINNAGIDDPRNQLLLKYFDFVDGLQPKAFLIENVAGLLWKRHENYLNQLLALAETHGYTIHFCGILNA
KDYGVPQNRKRVFIFGTRNDLKINNPAFPPDATHFAPTSKNGPKWKTASSVFEKLTSELIDFYIEDYFRPKTKMTDENAR
LLLASLEHGEPVNPTDVCNINMQPTPKMIIRFENTPLNGGREDSGYTLKCHSNGYKGHKDVYGRIMIHLPGNTITTGCNN
PSKGRFVHPWKNHGMTLRHAARFQTFPDSFNFIGTSTQQGKQIGNAVPVELGKVLINTIKRIITS
>Mature_385_residues
MKAIDLFSGAGGLSLAAHQCGIDVIAAIELDTAASITYRANLIEQLKAPTKLINGDINEVDLPALMKELKLKSGELELLL
GGPPCQGFSTHRINNAGIDDPRNQLLLKYFDFVDGLQPKAFLIENVAGLLWKRHENYLNQLLALAETHGYTIHFCGILNA
KDYGVPQNRKRVFIFGTRNDLKINNPAFPPDATHFAPTSKNGPKWKTASSVFEKLTSELIDFYIEDYFRPKTKMTDENAR
LLLASLEHGEPVNPTDVCNINMQPTPKMIIRFENTPLNGGREDSGYTLKCHSNGYKGHKDVYGRIMIHLPGNTITTGCNN
PSKGRFVHPWKNHGMTLRHAARFQTFPDSFNFIGTSTQQGKQIGNAVPVELGKVLINTIKRIITS

Specific function: This methylase recognizes the double-stranded sequence CGATCG, causes specific methylation on C-? on both strands and protects the DNA from cleavage by the XorII endonuclease [H]

COG id: COG0270

COG function: function code L; Site-specific DNA methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C5-methyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI195927037, Length=208, Percent_Identity=33.1730769230769, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4503351, Length=208, Percent_Identity=33.1730769230769, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018117
- InterPro:   IPR001525 [H]

Pfam domain/function: PF00145 DNA_methylase [H]

EC number: =2.1.1.37 [H]

Molecular weight: Translated: 42768; Mature: 42768

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: PS00094 C5_MTASE_1 ; PS00095 C5_MTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIDLFSGAGGLSLAAHQCGIDVIAAIELDTAASITYRANLIEQLKAPTKLINGDINEV
CCCEECCCCCCCCCHHHHHCCCEEEEEEEECCCCEEHHHHHHHHHHCCCHHHHCCCCCCC
DLPALMKELKLKSGELELLLGGPPCQGFSTHRINNAGIDDPRNQLLLKYFDFVDGLQPKA
CHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHH
FLIENVAGLLWKRHENYLNQLLALAETHGYTIHFCGILNAKDYGVPQNRKRVFIFGTRND
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCEEEEEECCCC
LKINNPAFPPDATHFAPTSKNGPKWKTASSVFEKLTSELIDFYIEDYFRPKTKMTDENAR
EEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCE
LLLASLEHGEPVNPTDVCNINMQPTPKMIIRFENTPLNGGREDSGYTLKCHSNGYKGHKD
EEEEECCCCCCCCCCCEEEECCCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCC
VYGRIMIHLPGNTITTGCNNPSKGRFVHPWKNHGMTLRHAARFQTFPDSFNFIGTSTQQG
CEEEEEEEECCCEEECCCCCCCCCCEECCHHHCCEEEEHHHHHCCCCCCCCCCCCCCHHH
KQIGNAVPVELGKVLINTIKRIITS
HHHCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKAIDLFSGAGGLSLAAHQCGIDVIAAIELDTAASITYRANLIEQLKAPTKLINGDINEV
CCCEECCCCCCCCCHHHHHCCCEEEEEEEECCCCEEHHHHHHHHHHCCCHHHHCCCCCCC
DLPALMKELKLKSGELELLLGGPPCQGFSTHRINNAGIDDPRNQLLLKYFDFVDGLQPKA
CHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHH
FLIENVAGLLWKRHENYLNQLLALAETHGYTIHFCGILNAKDYGVPQNRKRVFIFGTRND
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCEEEEEECCCC
LKINNPAFPPDATHFAPTSKNGPKWKTASSVFEKLTSELIDFYIEDYFRPKTKMTDENAR
EEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCE
LLLASLEHGEPVNPTDVCNINMQPTPKMIIRFENTPLNGGREDSGYTLKCHSNGYKGHKD
EEEEECCCCCCCCCCCEEEECCCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCC
VYGRIMIHLPGNTITTGCNNPSKGRFVHPWKNHGMTLRHAARFQTFPDSFNFIGTSTQQG
CEEEEEEEECCCEEECCCCCCCCCCEECCHHHCCEEEEHHHHHCCCCCCCCCCCCCCHHH
KQIGNAVPVELGKVLINTIKRIITS
HHHCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8078464 [H]